Bacteriophage therapy has played a significant role in research fields of molecular biology and biotechnology since a long time. Phage-based treatment therapy is expected to emerge as a new treatment for managing persistent bacterial infections. These factors are widening the potential scope for drug discovery. Increasing prevalence of drug-resistant infections is also expected to drive demand for bacteriophage therapy to help in overcoming an infection outbreak. For instance, as per the Centers for Disease Control and Prevention (CDC), in February 2019, around 129 people from 32 U.S. states were infected with the outbreak of strain Salmonella Infantis infection. Moreover, the CDC had conducted an antibiotic resistance testing on Salmonella bacteria isolated from infected patients, which showed that the outbreak strain was resistant to multiple antibiotics.
Increasing research and development of products is expected to propel the market growth. For instance, in September 2019, Armata Pharamceutical Inc. developed a new synthetic phage candidate targeting pathogen Pseudomonas aeruginosa for treatment of serious respiratory infections, with an emphasis on cystic fibrosis patients.
Market Dynamics
Increasing incidences of antibiotic resistance, rising adoption of inorganic growth strategies by key players, and increasing launches and approval of novel products is expected to drive the growth of global bacteriophage therapy market over the forecast period.
For instance, in February 2019, the U.S. Food and Drug Administration (FDA) accepted an Investigational New Drug (IND) application to conduct the first U.S. clinical trial of an intravenously administered bacteriophage-based therapy. The application for the clinical study was submitted by physician-scientists at the University Of California San Diego School Of Medicine. Following the U.S. FDA approval, the company plans to initiate phase I/II clinical trial study to test AB-SA01, an experimental bacteriophage combination for the treatment of participants with ventricular assist devices (VADs) infected by resistant Staphylococcus aureus (S. aureus).
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