Angina Pectoris - Drug Pipeline Landscape, 2023
Angina also known as angina pectoris, is a type of chest pain or discomfort that occurs when a part of the heart doesn't get enough blood and oxygen, which is due to the spasm or obstruction of the arteries that supply the blood to the heart muscles. Angina is mainly of four types: stable angina, unstable angina, microvascular angina, and vasospastic or variant angina.
Angina is caused due to the built up of plaque in the arteries. The major risk factors that are concerned with angina are smoking, age, stress, lack of physical activity, family history of premature cardiovascular diseases. Medical conditions that exacerbate angina are diabetes, dyslipidaemia, hypertension, kidney disease, polycythaemia, and it is also concerned with the use of medications such as vasodilators.
Symptoms that are associated with angina are chest pain or discomfort. Pain around epigastrium, neck, shoulders and back. Autonomic symptoms include nausea, vomiting, pallor, shortness of breath, squeezing and fatigue.
Angina can be diagnosed with the primary complains including chest pain or discomfort, chest tightness and precipitated by cold weather or a meal. Electrocardiogram is recommended to determine the ST elevations. Non-invasive testing includes coronary angiogram. Imaging testing includes echocardiogram, CT and MRI.
Angina treatment is aimed at providing sufficient oxygen supply to the heart. Common treatment options include anticoagulants, nitrates or calcium channel blocker, beta-blockers and statins. Angioplasty and sometimes coronary artery bypass grafting are recommended in severe disease condition. Lifestyle changes promotes towards healthier condition.
Major pharmaceutical companies are involved in the development of potential drug candidates to improve the Angina Pectoris treatment such as Ad5FGF-4, AR36, ACP-01 and others. Key players involved in the development of therapies to treat Angina Pectoris are Azurity Pharmaceuticals, Gene Biotherapeutics, Hemostemix Inc, Milestone Pharmaceuticals Inc, XyloCor Therapeutics Inc, and others. Two drugs are under late-stage Phase III clinical trials and four drugs are in Phase II clinical trials and some other drugs are under Phase I, Preclinical and Discovery stages of development.
Global Insight Service's, Angina Pectoris - Drug Pipeline Landscape, 2023 report provides an overview of the Angina Pectoris pipeline drugs. This report covers detailed insights on Angina Pectoris drugs under development, assessment by target, mechanism of action, route of administration and molecule type. Product pipeline by companies, stage of development and key regulatory designations, deals and milestones have been presented to provide insights and thus help industry participants in their decision making. Angina Pectoris pipeline report helps gain insights on drugs which are under development stage of drug development process across globally.
The research process includes extensive secondary research on public domain and other authentic sources to add or update the pipeline products information. The secondary research sources include, but are not limited to company websites, annual reports, financial reports, company pipeline chart, investor presentations and SEC filings, journals and conferences, and clinical trials registries.
The pipeline landscape report provides analysis of pipeline products based on several stages of development ranging from Discovery to Pre-Registration. The report provides a review of pipeline therapeutics by companies based on information derived from company and industry-specific sources. The pipeline report covers assessment of therapeutics by mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. Comprehensive profiles of the pipeline products with details such as company overview, development stage; molecule type, target, mechanism of action, route of administration, dosage form, regulatory designations, key deals, clinical trials, and key upcoming milestones are included.
Reasons to Buy
Helps to find and recognize significant therapeutics under development. Thorough understanding of pipeline structure and helps in developing corrective measures for pipeline projects.
Effective R&D strategies can be developed with deep knowledge of competitor information, analysis, and insights.
Plan collaborations with various industry partners that have role in some or the other stage of drug development such as contract manufacturing, co-development, contract research organization and commercialization etc.
Helps to create in-licensing and out-licensing opportunities by identifying prospective partners with attractive projects to expand business potential and scope.
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