Global Solid-phase Oligonucleotide Synthesis Market Research Report 2025(Status and Outlook)

Report Overview

Solid-phase oligonucleotide synthesis is a process used to chemically synthesize DNA or RNA molecules on a solid support. This method involves building nucleotide sequences step by step, starting from the 3' end to the 5' end. Solid-phase synthesis allows for the production of custom oligonucleotides with precise sequences, lengths, and modifications. The process typically involves the use of nucleotide phosphoramidites, which are added sequentially, followed by deprotection and cleavage from the solid support. Solid-phase oligonucleotide synthesis is widely used in various applications such as molecular biology research, diagnostics, therapeutics, and biotechnology.

The market for solid-phase oligonucleotide synthesis is experiencing significant growth driven by several key factors. One of the primary drivers is the increasing demand for custom oligonucleotides in research and development activities across various industries. Custom oligos are essential tools in molecular biology research, including PCR, sequencing, gene editing, and gene synthesis. Additionally, the rising adoption of oligonucleotides in diagnostics and therapeutics, such as antisense oligonucleotide drugs and RNA-based therapies, is fueling market growth. Moreover, advancements in synthesis technologies, automation, and high-throughput methods are enhancing the efficiency and scalability of solid-phase oligonucleotide synthesis, further driving market expansion. At the same time, the growing focus on personalized medicine and precision healthcare is creating opportunities for the development of novel oligonucleotide-based diagnostics and therapeutics, contributing to the overall market growth trend.

The global Solid-phase Oligonucleotide Synthesis market size was estimated at USD 491.73 million in 2024 and is projected to reach USD 1703.21 million by 2033, exhibiting a CAGR of 16.80% during the forecast period.

This report provides a deep insight into the global Solid-phase Oligonucleotide Synthesis market covering all its essential aspects. This ranges from a macro overview of the market to micro details of the market size, competitive landscape, development trend, niche market, key market drivers and challenges, SWOT analysis, Porter's five forces analysis, value chain analysis, PEST analysis, etc. In terms of regional markets, the report details the market space and development potential of each market segment in North America, Europe, Asia Pacific, South America, the Middle East and Africa, as well as the competitive landscape of major players, etc

The analysis helps the reader to shape the competition within the industries and strategies for the competitive environment to enhance the potential profit. Furthermore, it provides a simple framework for evaluating and accessing the position of the business organization. The report structure also focuses on the competitive landscape of the Global Solid-phase Oligonucleotide Synthesis Market, this report introduces in detail the market share, market performance, product situation, operation situation, etc. of the main players, which helps the readers in the industry to identify the main competitors and deeply understand the competition pattern of the market.

In a word, this report is a must-read for industry players, investors, researchers, consultants, business strategists, and all those who have any kind of stake or are planning to foray into the Solid-phase Oligonucleotide Synthesis market in any manner.

Global Solid-phase Oligonucleotide Synthesis Market: Market Segmentation Analysis

The research report includes specific segments by region (country), manufacturers, Type, and Application. Market segmentation creates subsets of a market based on product type, end-user or application, Geographic, and other factors. By understanding the market segments, the decision-maker can leverage this targeting in the product, sales, and marketing strategies. Market segments can power your product development cycles by informing how you create product offerings for different segments.

Key Company

Genescript

GeneArt (Thermofischer)

Renesas Electronics Corporation

DNA 2.0 (ATUM)

OriGene

BBI

Genewiz

Eurofins Genomics

Gene Oracle

SBS Genetech

Bio Basic

Market Segmentation (by Type)

Primers

Probes

Intermediate-scale Synthesis Oligos

Large-scale Synthesis Oligos

Linkers and Adaptors

Market Segmentation (by Application)

Commercial

Academic Research

Geographic Segmentation

North America (USA, Canada, Mexico)

Europe (Germany, UK, France, Russia, Italy, Rest of Europe)

Asia-Pacific (China, Japan, South Korea, India, Southeast Asia, Rest of Asia-Pacific)

South America (Brazil, Argentina, Columbia, Rest of South America)

The Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria, South Africa, Rest of MEA)

Key Benefits of This Market Research:

Industry drivers, restraints, and opportunities covered in the study

Neutral perspective on the market performance

Recent industry trends and developments

Competitive landscape & strategies of key players

Potential & niche segments and regions exhibiting promising growth covered

Historical, current, and projected market size, in terms of value

In-depth analysis of the Solid-phase Oligonucleotide Synthesis Market

Overview of the regional outlook of the Solid-phase Oligonucleotide Synthesis Market:

Chapter Outline

Chapter 1 mainly introduces the statistical scope of the report, market division standards, and market research methods.

Chapter 2 is an executive summary of different market segments (by region, product type, application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the Solid-phase Oligonucleotide Synthesis Market and its likely evolution in the short to mid-term, and long term.

Chapter 3 makes a detailed analysis of the market's competitive landscape of the market and provides the market share, capacity, output, price, latest development plan, merger, and acquisition information of the main manufacturers in the market.

Chapter 4 is the analysis of the whole market industrial chain, including the upstream and downstream of the industry, as well as Porter's five forces analysis.

Chapter 5 introduces the latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.

Chapter 6 provides the analysis of various market segments according to product types, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.

Chapter 7 provides the analysis of various market segments according to application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.

Chapter 8 provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and capacity of each country in the world.

Chapter 9 shares the main producing countries of Solid-phase Oligonucleotide Synthesis, their output value, profit level, regional supply, production capacity layout, etc. from the supply side.

Chapter 10 introduces the basic situation of the main companies in the market in detail, including product sales revenue, sales volume, price, gross profit margin, market share, product introduction, recent development, etc.

Chapter 11 provides a quantitative analysis of the market size and development potential of each region in the next five years.

Chapter 12 provides a quantitative analysis of the market size and development potential of each market segment in the next five years.

Chapter 13 is the main points and conclusions of the report.

Key Reasons to Buy this Report:

Access to date statistics compiled by our researchers. These provide you with historical and forecast data, which is analyzed to tell you why your market is set to change

This enables you to anticipate market changes to remain ahead of your competitors

You will be able to copy data from the Excel spreadsheet straight into your marketing plans, business presentations, or other strategic documents

The concise analysis, clear graph, and table format will enable you to pinpoint the information you require quickly

Provision of market value data for each segment and sub-segment

Indicates the region and segment that is expected to witness the fastest growth as well as to dominate the market

Analysis by geography highlighting the consumption of the product/service in the region as well as indicating the factors that are affecting the market within each region

Competitive landscape which incorporates the market ranking of the major players, along with new service/product launches, partnerships, business expansions, and acquisitions in the past five years of companies profiled

Extensive company profiles comprising of company overview, company insights, product benchmarking, and SWOT analysis for the major market players

The current as well as the future market outlook of the industry concerning recent developments which involve growth opportunities and drivers as well as challenges and restraints of both emerging as well as developed regions

Includes in-depth analysis of the market from various perspectives through Porter’s five forces analysis

Provides insight into the market through Value Chain

Market dynamics scenario, along with growth opportunities of the market in the years to come


1 Research Methodology and Statistical Scope
1.1 Market Definition and Statistical Scope of Solid-phase Oligonucleotide Synthesis
1.2 Key Market Segments
1.2.1 Solid-phase Oligonucleotide Synthesis Segment by Type
1.2.2 Solid-phase Oligonucleotide Synthesis Segment by Application
1.3 Methodology & Sources of Information
1.3.1 Research Methodology
1.3.2 Research Process
1.3.3 Market Breakdown and Data Triangulation
1.3.4 Base Year
1.3.5 Report Assumptions & Caveats
2 Solid-phase Oligonucleotide Synthesis Market Overview
2.1 Global Market Overview
2.1.1 Global Solid-phase Oligonucleotide Synthesis Market Size (M USD) Estimates and Forecasts (2020-2033)
2.1.2 Global Solid-phase Oligonucleotide Synthesis Sales Estimates and Forecasts (2020-2033)
2.2 Market Segment Executive Summary
2.3 Global Market Size by Region
3 Solid-phase Oligonucleotide Synthesis Market Competitive Landscape
3.1 Company Assessment Quadrant
3.2 Global Solid-phase Oligonucleotide Synthesis Product Life Cycle
3.3 Global Solid-phase Oligonucleotide Synthesis Sales by Manufacturers (2020-2025)
3.4 Global Solid-phase Oligonucleotide Synthesis Revenue Market Share by Manufacturers (2020-2025)
3.5 Solid-phase Oligonucleotide Synthesis Market Share by Company Type (Tier 1, Tier 2, and Tier 3)
3.6 Global Solid-phase Oligonucleotide Synthesis Average Price by Manufacturers (2020-2025)
3.7 Manufacturers Solid-phase Oligonucleotide Synthesis Manufacturing Sites, Area Served, Product Type
3.8 Solid-phase Oligonucleotide Synthesis Market Competitive Situation and Trends
3.8.1 Solid-phase Oligonucleotide Synthesis Market Concentration Rate
3.8.2 Global 5 and 10 Largest Solid-phase Oligonucleotide Synthesis Players Market Share by Revenue
3.8.3 Mergers & Acquisitions, Expansion
4 Solid-phase Oligonucleotide Synthesis Industry Chain Analysis
4.1 Solid-phase Oligonucleotide Synthesis Industry Chain Analysis
4.2 Market Overview of Key Raw Materials
4.3 Midstream Market Analysis
4.4 Downstream Customer Analysis
5 The Development and Dynamics of Solid-phase Oligonucleotide Synthesis Market
5.1 Key Development Trends
5.2 Driving Factors
5.3 Market Challenges
5.4 Industry News
5.4.1 New Product Developments
5.4.2 Mergers & Acquisitions
5.4.3 Expansions
5.4.4 Collaboration/Supply Contracts
5.5 PEST Analysis
5.5.1 Industry Policies Analysis
5.5.2 Economic Environment Analysis
5.5.3 Social Environment Analysis
5.5.4 Technological Environment Analysis
5.6 Global Solid-phase Oligonucleotide Synthesis Market Porter's Five Forces Analysis
5.6.1 Global Trade Frictions
5.6.2 Global Trade Frictions and Their Impacts to Solid-phase Oligonucleotide Synthesis Market
5.7 ESG Ratings of Leading Companies
6 Solid-phase Oligonucleotide Synthesis Market Segmentation by Type
6.1 Evaluation Matrix of Segment Market Development Potential (Type)
6.2 Global Solid-phase Oligonucleotide Synthesis Sales Market Share by Type (2020-2025)
6.3 Global Solid-phase Oligonucleotide Synthesis Market Size Market Share by Type (2020-2025)
6.4 Global Solid-phase Oligonucleotide Synthesis Price by Type (2020-2025)
7 Solid-phase Oligonucleotide Synthesis Market Segmentation by Application
7.1 Evaluation Matrix of Segment Market Development Potential (Application)
7.2 Global Solid-phase Oligonucleotide Synthesis Market Sales by Application (2020-2025)
7.3 Global Solid-phase Oligonucleotide Synthesis Market Size (M USD) by Application (2020-2025)
7.4 Global Solid-phase Oligonucleotide Synthesis Sales Growth Rate by Application (2020-2025)
8 Solid-phase Oligonucleotide Synthesis Market Sales by Region
8.1 Global Solid-phase Oligonucleotide Synthesis Sales by Region
8.1.1 Global Solid-phase Oligonucleotide Synthesis Sales by Region
8.1.2 Global Solid-phase Oligonucleotide Synthesis Sales Market Share by Region
8.2 Global Solid-phase Oligonucleotide Synthesis Market Size by Region
8.2.1 Global Solid-phase Oligonucleotide Synthesis Market Size by Region
8.2.2 Global Solid-phase Oligonucleotide Synthesis Market Size Market Share by Region
8.3 North America
8.3.1 North America Solid-phase Oligonucleotide Synthesis Sales by Country
8.3.2 North America Solid-phase Oligonucleotide Synthesis Market Size by Country
8.3.3 U.S. Market Overview
8.3.4 Canada Market Overview
8.3.5 Mexico Market Overview
8.4 Europe
8.4.1 Europe Solid-phase Oligonucleotide Synthesis Sales by Country
8.4.2 Europe Solid-phase Oligonucleotide Synthesis Market Size by Country
8.4.3 Germany Market Overview
8.4.4 France Market Overview
8.4.5 U.K. Market Overview
8.4.6 Italy Market Overview
8.4.7 Spain Market Overview
8.5 Asia Pacific
8.5.1 Asia Pacific Solid-phase Oligonucleotide Synthesis Sales by Region
8.5.2 Asia Pacific Solid-phase Oligonucleotide Synthesis Market Size by Region
8.5.3 China Market Overview
8.5.4 Japan Market Overview
8.5.5 South Korea Market Overview
8.5.6 India Market Overview
8.5.7 Southeast Asia Market Overview
8.6 South America
8.6.1 South America Solid-phase Oligonucleotide Synthesis Sales by Country
8.6.2 South America Solid-phase Oligonucleotide Synthesis Market Size by Country
8.6.3 Brazil Market Overview
8.6.4 Argentina Market Overview
8.6.5 Columbia Market Overview
8.7 Middle East and Africa
8.7.1 Middle East and Africa Solid-phase Oligonucleotide Synthesis Sales by Region
8.7.2 Middle East and Africa Solid-phase Oligonucleotide Synthesis Market Size by Region
8.7.3 Saudi Arabia Market Overview
8.7.4 UAE Market Overview
8.7.5 Egypt Market Overview
8.7.6 Nigeria Market Overview
8.7.7 South Africa Market Overview
9 Solid-phase Oligonucleotide Synthesis Market Production by Region
9.1 Global Production of Solid-phase Oligonucleotide Synthesis by Region(2020-2025)
9.2 Global Solid-phase Oligonucleotide Synthesis Revenue Market Share by Region (2020-2025)
9.3 Global Solid-phase Oligonucleotide Synthesis Production, Revenue, Price and Gross Margin (2020-2025)
9.4 North America Solid-phase Oligonucleotide Synthesis Production
9.4.1 North America Solid-phase Oligonucleotide Synthesis Production Growth Rate (2020-2025)
9.4.2 North America Solid-phase Oligonucleotide Synthesis Production, Revenue, Price and Gross Margin (2020-2025)
9.5 Europe Solid-phase Oligonucleotide Synthesis Production
9.5.1 Europe Solid-phase Oligonucleotide Synthesis Production Growth Rate (2020-2025)
9.5.2 Europe Solid-phase Oligonucleotide Synthesis Production, Revenue, Price and Gross Margin (2020-2025)
9.6 Japan Solid-phase Oligonucleotide Synthesis Production (2020-2025)
9.6.1 Japan Solid-phase Oligonucleotide Synthesis Production Growth Rate (2020-2025)
9.6.2 Japan Solid-phase Oligonucleotide Synthesis Production, Revenue, Price and Gross Margin (2020-2025)
9.7 China Solid-phase Oligonucleotide Synthesis Production (2020-2025)
9.7.1 China Solid-phase Oligonucleotide Synthesis Production Growth Rate (2020-2025)
9.7.2 China Solid-phase Oligonucleotide Synthesis Production, Revenue, Price and Gross Margin (2020-2025)
10 Key Companies Profile
10.1 Genescript
10.1.1 Genescript Basic Information
10.1.2 Genescript Solid-phase Oligonucleotide Synthesis Product Overview
10.1.3 Genescript Solid-phase Oligonucleotide Synthesis Product Market Performance
10.1.4 Genescript Business Overview
10.1.5 Genescript SWOT Analysis
10.1.6 Genescript Recent Developments
10.2 GeneArt (Thermofischer)
10.2.1 GeneArt (Thermofischer) Basic Information
10.2.2 GeneArt (Thermofischer) Solid-phase Oligonucleotide Synthesis Product Overview
10.2.3 GeneArt (Thermofischer) Solid-phase Oligonucleotide Synthesis Product Market Performance
10.2.4 GeneArt (Thermofischer) Business Overview
10.2.5 GeneArt (Thermofischer) SWOT Analysis
10.2.6 GeneArt (Thermofischer) Recent Developments
10.3 Renesas Electronics Corporation
10.3.1 Renesas Electronics Corporation Basic Information
10.3.2 Renesas Electronics Corporation Solid-phase Oligonucleotide Synthesis Product Overview
10.3.3 Renesas Electronics Corporation Solid-phase Oligonucleotide Synthesis Product Market Performance
10.3.4 Renesas Electronics Corporation Business Overview
10.3.5 Renesas Electronics Corporation SWOT Analysis
10.3.6 Renesas Electronics Corporation Recent Developments
10.4 DNA 2.0 (ATUM)
10.4.1 DNA 2.0 (ATUM) Basic Information
10.4.2 DNA 2.0 (ATUM) Solid-phase Oligonucleotide Synthesis Product Overview
10.4.3 DNA 2.0 (ATUM) Solid-phase Oligonucleotide Synthesis Product Market Performance
10.4.4 DNA 2.0 (ATUM) Business Overview
10.4.5 DNA 2.0 (ATUM) Recent Developments
10.5 OriGene
10.5.1 OriGene Basic Information
10.5.2 OriGene Solid-phase Oligonucleotide Synthesis Product Overview
10.5.3 OriGene Solid-phase Oligonucleotide Synthesis Product Market Performance
10.5.4 OriGene Business Overview
10.5.5 OriGene Recent Developments
10.6 BBI
10.6.1 BBI Basic Information
10.6.2 BBI Solid-phase Oligonucleotide Synthesis Product Overview
10.6.3 BBI Solid-phase Oligonucleotide Synthesis Product Market Performance
10.6.4 BBI Business Overview
10.6.5 BBI Recent Developments
10.7 Genewiz
10.7.1 Genewiz Basic Information
10.7.2 Genewiz Solid-phase Oligonucleotide Synthesis Product Overview
10.7.3 Genewiz Solid-phase Oligonucleotide Synthesis Product Market Performance
10.7.4 Genewiz Business Overview
10.7.5 Genewiz Recent Developments
10.8 Eurofins Genomics
10.8.1 Eurofins Genomics Basic Information
10.8.2 Eurofins Genomics Solid-phase Oligonucleotide Synthesis Product Overview
10.8.3 Eurofins Genomics Solid-phase Oligonucleotide Synthesis Product Market Performance
10.8.4 Eurofins Genomics Business Overview
10.8.5 Eurofins Genomics Recent Developments
10.9 Gene Oracle
10.9.1 Gene Oracle Basic Information
10.9.2 Gene Oracle Solid-phase Oligonucleotide Synthesis Product Overview
10.9.3 Gene Oracle Solid-phase Oligonucleotide Synthesis Product Market Performance
10.9.4 Gene Oracle Business Overview
10.9.5 Gene Oracle Recent Developments
10.10 SBS Genetech
10.10.1 SBS Genetech Basic Information
10.10.2 SBS Genetech Solid-phase Oligonucleotide Synthesis Product Overview
10.10.3 SBS Genetech Solid-phase Oligonucleotide Synthesis Product Market Performance
10.10.4 SBS Genetech Business Overview
10.10.5 SBS Genetech Recent Developments
10.11 Bio Basic
10.11.1 Bio Basic Basic Information
10.11.2 Bio Basic Solid-phase Oligonucleotide Synthesis Product Overview
10.11.3 Bio Basic Solid-phase Oligonucleotide Synthesis Product Market Performance
10.11.4 Bio Basic Business Overview
10.11.5 Bio Basic Recent Developments
11 Solid-phase Oligonucleotide Synthesis Market Forecast by Region
11.1 Global Solid-phase Oligonucleotide Synthesis Market Size Forecast
11.2 Global Solid-phase Oligonucleotide Synthesis Market Forecast by Region
11.2.1 North America Market Size Forecast by Country
11.2.2 Europe Solid-phase Oligonucleotide Synthesis Market Size Forecast by Country
11.2.3 Asia Pacific Solid-phase Oligonucleotide Synthesis Market Size Forecast by Region
11.2.4 South America Solid-phase Oligonucleotide Synthesis Market Size Forecast by Country
11.2.5 Middle East and Africa Forecasted Sales of Solid-phase Oligonucleotide Synthesis by Country
12 Forecast Market by Type and by Application (2026-2033)
12.1 Global Solid-phase Oligonucleotide Synthesis Market Forecast by Type (2026-2033)
12.1.1 Global Forecasted Sales of Solid-phase Oligonucleotide Synthesis by Type (2026-2033)
12.1.2 Global Solid-phase Oligonucleotide Synthesis Market Size Forecast by Type (2026-2033)
12.1.3 Global Forecasted Price of Solid-phase Oligonucleotide Synthesis by Type (2026-2033)
12.2 Global Solid-phase Oligonucleotide Synthesis Market Forecast by Application (2026-2033)
12.2.1 Global Solid-phase Oligonucleotide Synthesis Sales (K Units) Forecast by Application
12.2.2 Global Solid-phase Oligonucleotide Synthesis Market Size (M USD) Forecast by Application (2026-2033)
13 Conclusion and Key Findings

Download our eBook: How to Succeed Using Market Research

Learn how to effectively navigate the market research process to help guide your organization on the journey to success.

Download eBook
Cookie Settings