Global Single Injection Hyaluronic Acid Viscosupplement Market Research Report 2025(Status and Outlook)

Report Overview

Single injection hyaluronic acid (HA) viscosupplements are intra-articular treatments designed to alleviate pain and improve joint function in patients with osteoarthritis (OA), particularly in the knee. These products consist of cross-linked or high-molecular-weight HA formulations that provide lubrication, shock absorption, and anti-inflammatory effects with just one administration, offering convenience over traditional multi-injection therapies. Marketed as a minimally invasive alternative to surgery, they cater to patients seeking long-lasting relief with fewer clinic visits. The global market is driven by rising OA prevalence, aging populations, and demand for non-opioid pain management solutions. However, reimbursement challenges, competition from generic HA products, and emerging regenerative therapies (e.g., platelet-rich plasma, stem cells) pose constraints. Key players differentiate through proprietary HA technologies, duration of efficacy claims, and expansion into emerging markets with unmet medical needs. Regulatory approvals and clinical outcomes emphasizing patient-reported pain reduction remain critical for adoption.

The global Single Injection Hyaluronic Acid Viscosupplement market size was estimated at USD 226.62 million in 2024, exhibiting a CAGR of 8.20% during the forecast period.

This report provides a deep insight into the global Single Injection Hyaluronic Acid Viscosupplement market covering all its essential aspects. This ranges from a macro overview of the market to micro details of the market size, competitive landscape, development trend, niche market, key market drivers and challenges, SWOT analysis, value chain analysis, etc.

The analysis helps the reader to shape the competition within the industries and strategies for the competitive environment to enhance the potential profit. Furthermore, it provides a simple framework for evaluating and accessing the position of the business organization. The report structure also focuses on the competitive landscape of the Global Single Injection Hyaluronic Acid Viscosupplement Market, this report introduces in detail the market share, market performance, product situation, operation situation, etc. of the main players, which helps the readers in the industry to identify the main competitors and deeply understand the competition pattern of the market.

In a word, this report is a must-read for industry players, investors, researchers, consultants, business strategists, and all those who have any kind of stake or are planning to foray into the Single Injection Hyaluronic Acid Viscosupplement market in any manner.

Global Single Injection Hyaluronic Acid Viscosupplement Market: Market Segmentation Analysis

The research report includes specific segments by region (country), manufacturers, Type, and Application. Market segmentation creates subsets of a market based on product type, end-user or application, Geographic, and other factors. By understanding the market segments, the decision-maker can leverage this targeting in the product, sales, and marketing strategies. Market segments can power your product development cycles by informing how you create product offerings for different segments.

Key Company

Anika Therapeutics

Sanofi Genzyme

Bioventus

Fidia Farmaceutici SpA

Zimmer Biomet

Orthovisc

Croma-Pharma

TRB Chemedica

Market Segmentation (by Type)

Cross-Linked Hyaluronic Acid Viscosupplement

Non-cross-linked Hyaluronic Acid Viscosupplement

Market Segmentation (by Application)

Hospital

Clinic

Other

Geographic Segmentation

North America (USA, Canada, Mexico)

Europe (Germany, UK, France, Russia, Italy, Rest of Europe)

Asia-Pacific (China, Japan, South Korea, India, Southeast Asia, Rest of Asia-Pacific)

South America (Brazil, Argentina, Columbia, Rest of South America)

The Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria, South Africa, Rest of MEA)

Key Benefits of This Market Research:

Industry drivers, restraints, and opportunities covered in the study

Neutral perspective on the market performance

Recent industry trends and developments

Competitive landscape & strategies of key players

Potential & niche segments and regions exhibiting promising growth covered

Historical, current, and projected market size, in terms of value

In-depth analysis of the Single Injection Hyaluronic Acid Viscosupplement Market

Overview of the regional outlook of the Single Injection Hyaluronic Acid Viscosupplement Market:

Chapter Outline

Chapter 1 mainly introduces the statistical scope of the report, market division standards, and market research methods.

Chapter 2 is an executive summary of different market segments (by region, product type, application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the Single Injection Hyaluronic Acid Viscosupplement Market and its likely evolution in the short to mid-term, and long term.

Chapter 3 makes a detailed analysis of the market's competitive landscape of the market and provides the market share, capacity, output, price, latest development plan, merger, and acquisition information of the main manufacturers in the market.

Chapter 4 is the analysis of the whole market industrial chain, including the upstream and downstream of the industry, as well as Porter's five forces analysis.

Chapter 5 introduces the latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.

Chapter 6 provides the analysis of various market segments according to product types, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.

Chapter 7 provides the analysis of various market segments according to application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.

Chapter 8 provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and capacity of each country in the world.

Chapter 9 shares the main producing countries of Single Injection Hyaluronic Acid Viscosupplement, their output value, profit level, regional supply, production capacity layout, etc. from the supply side.

Chapter 10 introduces the basic situation of the main companies in the market in detail, including product sales revenue, sales volume, price, gross profit margin, market share, product introduction, recent development, etc.

Chapter 11 provides a quantitative analysis of the market size and development potential of each region in the next five years.

Chapter 12 provides a quantitative analysis of the market size and development potential of each market segment in the next five years.

Chapter 13 is the main points and conclusions of the report.

Key Reasons to Buy this Report:

Access to date statistics compiled by our researchers. These provide you with historical and forecast data, which is analyzed to tell you why your market is set to change

This enables you to anticipate market changes to remain ahead of your competitors

You will be able to copy data from the Excel spreadsheet straight into your marketing plans, business presentations, or other strategic documents

The concise analysis, clear graph, and table format will enable you to pinpoint the information you require quickly

Provision of market value data for each segment and sub-segment

Indicates the region and segment that is expected to witness the fastest growth as well as to dominate the market

Analysis by geography highlighting the consumption of the product/service in the region as well as indicating the factors that are affecting the market within each region

Competitive landscape which incorporates the market ranking of the major players, along with new service/product launches, partnerships, business expansions, and acquisitions in the past five years of companies profiled

Extensive company profiles comprising of company overview, company insights, product benchmarking, and SWOT analysis for the major market players

The current as well as the future market outlook of the industry concerning recent developments which involve growth opportunities and drivers as well as challenges and restraints of both emerging as well as developed regions

Includes in-depth analysis of the market from various perspectives through Porter’s five forces analysis

Provides insight into the market through Value Chain

Market dynamics scenario, along with growth opportunities of the market in the years to come


1 Research Methodology and Statistical Scope
1.1 Market Definition and Statistical Scope of Single Injection Hyaluronic Acid Viscosupplement
1.2 Key Market Segments
1.2.1 Single Injection Hyaluronic Acid Viscosupplement Segment by Type
1.2.2 Single Injection Hyaluronic Acid Viscosupplement Segment by Application
1.3 Methodology & Sources of Information
1.3.1 Research Methodology
1.3.2 Research Process
1.3.3 Market Breakdown and Data Triangulation
1.3.4 Base Year
1.3.5 Report Assumptions & Caveats
2 Single Injection Hyaluronic Acid Viscosupplement Market Overview
2.1 Global Market Overview
2.1.1 Global Single Injection Hyaluronic Acid Viscosupplement Market Size (M USD) Estimates and Forecasts (2020-2033)
2.1.2 Global Single Injection Hyaluronic Acid Viscosupplement Sales Estimates and Forecasts (2020-2033)
2.2 Market Segment Executive Summary
2.3 Global Market Size by Region
3 Single Injection Hyaluronic Acid Viscosupplement Market Competitive Landscape
3.1 Company Assessment Quadrant
3.2 Global Single Injection Hyaluronic Acid Viscosupplement Product Life Cycle
3.3 Global Single Injection Hyaluronic Acid Viscosupplement Sales by Manufacturers (2020-2025)
3.4 Global Single Injection Hyaluronic Acid Viscosupplement Revenue Market Share by Manufacturers (2020-2025)
3.5 Single Injection Hyaluronic Acid Viscosupplement Market Share by Company Type (Tier 1, Tier 2, and Tier 3)
3.6 Global Single Injection Hyaluronic Acid Viscosupplement Average Price by Manufacturers (2020-2025)
3.7 Manufacturers’ Manufacturing Sites, Areas Served, and Product Types
3.8 Single Injection Hyaluronic Acid Viscosupplement Market Competitive Situation and Trends
3.8.1 Single Injection Hyaluronic Acid Viscosupplement Market Concentration Rate
3.8.2 Global 5 and 10 Largest Single Injection Hyaluronic Acid Viscosupplement Players Market Share by Revenue
3.8.3 Mergers & Acquisitions, Expansion
4 Single Injection Hyaluronic Acid Viscosupplement Industry Chain Analysis
4.1 Single Injection Hyaluronic Acid Viscosupplement Industry Chain Analysis
4.2 Market Overview of Key Raw Materials
4.3 Midstream Market Analysis
4.4 Downstream Customer Analysis
5 The Development and Dynamics of Single Injection Hyaluronic Acid Viscosupplement Market
5.1 Key Development Trends
5.2 Driving Factors
5.3 Market Challenges
5.4 Industry News
5.4.1 New Product Developments
5.4.2 Mergers & Acquisitions
5.4.3 Expansions
5.4.4 Collaboration/Supply Contracts
5.5 PEST Analysis
5.5.1 Industry Policies Analysis
5.5.2 Economic Environment Analysis
5.5.3 Social Environment Analysis
5.5.4 Technological Environment Analysis
5.6 Global Single Injection Hyaluronic Acid Viscosupplement Market Porter's Five Forces Analysis
5.6.1 Global Trade Frictions
5.6.2 U.S. Tariff Policy – April 2025
5.6.3 Global Trade Frictions and Their Impacts to Single Injection Hyaluronic Acid Viscosupplement Market
5.7 ESG Ratings of Leading Companies
6 Single Injection Hyaluronic Acid Viscosupplement Market Segmentation by Type
6.1 Evaluation Matrix of Segment Market Development Potential (Type)
6.2 Global Single Injection Hyaluronic Acid Viscosupplement Sales Market Share by Type (2020-2025)
6.3 Global Single Injection Hyaluronic Acid Viscosupplement Market Size Market Share by Type (2020-2025)
6.4 Global Single Injection Hyaluronic Acid Viscosupplement Price by Type (2020-2025)
7 Single Injection Hyaluronic Acid Viscosupplement Market Segmentation by Application
7.1 Evaluation Matrix of Segment Market Development Potential (Application)
7.2 Global Single Injection Hyaluronic Acid Viscosupplement Market Sales by Application (2020-2025)
7.3 Global Single Injection Hyaluronic Acid Viscosupplement Market Size (M USD) by Application (2020-2025)
7.4 Global Single Injection Hyaluronic Acid Viscosupplement Sales Growth Rate by Application (2020-2025)
8 Single Injection Hyaluronic Acid Viscosupplement Market Sales by Region
8.1 Global Single Injection Hyaluronic Acid Viscosupplement Sales by Region
8.1.1 Global Single Injection Hyaluronic Acid Viscosupplement Sales by Region
8.1.2 Global Single Injection Hyaluronic Acid Viscosupplement Sales Market Share by Region
8.2 Global Single Injection Hyaluronic Acid Viscosupplement Market Size by Region
8.2.1 Global Single Injection Hyaluronic Acid Viscosupplement Market Size by Region
8.2.2 Global Single Injection Hyaluronic Acid Viscosupplement Market Size Market Share by Region
8.3 North America
8.3.1 North America Single Injection Hyaluronic Acid Viscosupplement Sales by Country
8.3.2 North America Single Injection Hyaluronic Acid Viscosupplement Market Size by Country
8.3.3 U.S. Market Overview
8.3.4 Canada Market Overview
8.3.5 Mexico Market Overview
8.4 Europe
8.4.1 Europe Single Injection Hyaluronic Acid Viscosupplement Sales by Country
8.4.2 Europe Single Injection Hyaluronic Acid Viscosupplement Market Size by Country
8.4.3 Germany Market Overview
8.4.4 France Market Overview
8.4.5 U.K. Market Overview
8.4.6 Italy Market Overview
8.4.7 Spain Market Overview
8.5 Asia Pacific
8.5.1 Asia Pacific Single Injection Hyaluronic Acid Viscosupplement Sales by Region
8.5.2 Asia Pacific Single Injection Hyaluronic Acid Viscosupplement Market Size by Region
8.5.3 China Market Overview
8.5.4 Japan Market Overview
8.5.5 South Korea Market Overview
8.5.6 India Market Overview
8.5.7 Southeast Asia Market Overview
8.6 South America
8.6.1 South America Single Injection Hyaluronic Acid Viscosupplement Sales by Country
8.6.2 South America Single Injection Hyaluronic Acid Viscosupplement Market Size by Country
8.6.3 Brazil Market Overview
8.6.4 Argentina Market Overview
8.6.5 Columbia Market Overview
8.7 Middle East and Africa
8.7.1 Middle East and Africa Single Injection Hyaluronic Acid Viscosupplement Sales by Region
8.7.2 Middle East and Africa Single Injection Hyaluronic Acid Viscosupplement Market Size by Region
8.7.3 Saudi Arabia Market Overview
8.7.4 UAE Market Overview
8.7.5 Egypt Market Overview
8.7.6 Nigeria Market Overview
8.7.7 South Africa Market Overview
9 Single Injection Hyaluronic Acid Viscosupplement Market Production by Region
9.1 Global Production of Single Injection Hyaluronic Acid Viscosupplement by Region(2020-2025)
9.2 Global Single Injection Hyaluronic Acid Viscosupplement Revenue Market Share by Region (2020-2025)
9.3 Global Single Injection Hyaluronic Acid Viscosupplement Production, Revenue, Price and Gross Margin (2020-2025)
9.4 North America Single Injection Hyaluronic Acid Viscosupplement Production
9.4.1 North America Single Injection Hyaluronic Acid Viscosupplement Production Growth Rate (2020-2025)
9.4.2 North America Single Injection Hyaluronic Acid Viscosupplement Production, Revenue, Price and Gross Margin (2020-2025)
9.5 Europe Single Injection Hyaluronic Acid Viscosupplement Production
9.5.1 Europe Single Injection Hyaluronic Acid Viscosupplement Production Growth Rate (2020-2025)
9.5.2 Europe Single Injection Hyaluronic Acid Viscosupplement Production, Revenue, Price and Gross Margin (2020-2025)
9.6 Japan Single Injection Hyaluronic Acid Viscosupplement Production (2020-2025)
9.6.1 Japan Single Injection Hyaluronic Acid Viscosupplement Production Growth Rate (2020-2025)
9.6.2 Japan Single Injection Hyaluronic Acid Viscosupplement Production, Revenue, Price and Gross Margin (2020-2025)
9.7 China Single Injection Hyaluronic Acid Viscosupplement Production (2020-2025)
9.7.1 China Single Injection Hyaluronic Acid Viscosupplement Production Growth Rate (2020-2025)
9.7.2 China Single Injection Hyaluronic Acid Viscosupplement Production, Revenue, Price and Gross Margin (2020-2025)
10 Key Companies Profile
10.1 Anika Therapeutics
10.1.1 Anika Therapeutics Basic Information
10.1.2 Anika Therapeutics Single Injection Hyaluronic Acid Viscosupplement Product Overview
10.1.3 Anika Therapeutics Single Injection Hyaluronic Acid Viscosupplement Product Market Performance
10.1.4 Anika Therapeutics Business Overview
10.1.5 Anika Therapeutics SWOT Analysis
10.1.6 Anika Therapeutics Recent Developments
10.2 Sanofi Genzyme
10.2.1 Sanofi Genzyme Basic Information
10.2.2 Sanofi Genzyme Single Injection Hyaluronic Acid Viscosupplement Product Overview
10.2.3 Sanofi Genzyme Single Injection Hyaluronic Acid Viscosupplement Product Market Performance
10.2.4 Sanofi Genzyme Business Overview
10.2.5 Sanofi Genzyme SWOT Analysis
10.2.6 Sanofi Genzyme Recent Developments
10.3 Bioventus
10.3.1 Bioventus Basic Information
10.3.2 Bioventus Single Injection Hyaluronic Acid Viscosupplement Product Overview
10.3.3 Bioventus Single Injection Hyaluronic Acid Viscosupplement Product Market Performance
10.3.4 Bioventus Business Overview
10.3.5 Bioventus SWOT Analysis
10.3.6 Bioventus Recent Developments
10.4 Fidia Farmaceutici SpA
10.4.1 Fidia Farmaceutici SpA Basic Information
10.4.2 Fidia Farmaceutici SpA Single Injection Hyaluronic Acid Viscosupplement Product Overview
10.4.3 Fidia Farmaceutici SpA Single Injection Hyaluronic Acid Viscosupplement Product Market Performance
10.4.4 Fidia Farmaceutici SpA Business Overview
10.4.5 Fidia Farmaceutici SpA Recent Developments
10.5 Zimmer Biomet
10.5.1 Zimmer Biomet Basic Information
10.5.2 Zimmer Biomet Single Injection Hyaluronic Acid Viscosupplement Product Overview
10.5.3 Zimmer Biomet Single Injection Hyaluronic Acid Viscosupplement Product Market Performance
10.5.4 Zimmer Biomet Business Overview
10.5.5 Zimmer Biomet Recent Developments
10.6 Orthovisc
10.6.1 Orthovisc Basic Information
10.6.2 Orthovisc Single Injection Hyaluronic Acid Viscosupplement Product Overview
10.6.3 Orthovisc Single Injection Hyaluronic Acid Viscosupplement Product Market Performance
10.6.4 Orthovisc Business Overview
10.6.5 Orthovisc Recent Developments
10.7 Croma-Pharma
10.7.1 Croma-Pharma Basic Information
10.7.2 Croma-Pharma Single Injection Hyaluronic Acid Viscosupplement Product Overview
10.7.3 Croma-Pharma Single Injection Hyaluronic Acid Viscosupplement Product Market Performance
10.7.4 Croma-Pharma Business Overview
10.7.5 Croma-Pharma Recent Developments
10.8 TRB Chemedica
10.8.1 TRB Chemedica Basic Information
10.8.2 TRB Chemedica Single Injection Hyaluronic Acid Viscosupplement Product Overview
10.8.3 TRB Chemedica Single Injection Hyaluronic Acid Viscosupplement Product Market Performance
10.8.4 TRB Chemedica Business Overview
10.8.5 TRB Chemedica Recent Developments
11 Single Injection Hyaluronic Acid Viscosupplement Market Forecast by Region
11.1 Global Single Injection Hyaluronic Acid Viscosupplement Market Size Forecast
11.2 Global Single Injection Hyaluronic Acid Viscosupplement Market Forecast by Region
11.2.1 North America Market Size Forecast by Country
11.2.2 Europe Single Injection Hyaluronic Acid Viscosupplement Market Size Forecast by Country
11.2.3 Asia Pacific Single Injection Hyaluronic Acid Viscosupplement Market Size Forecast by Region
11.2.4 South America Single Injection Hyaluronic Acid Viscosupplement Market Size Forecast by Country
11.2.5 Middle East and Africa Forecasted Sales of Single Injection Hyaluronic Acid Viscosupplement by Country
12 Forecast Market by Type and by Application (2026-2033)
12.1 Global Single Injection Hyaluronic Acid Viscosupplement Market Forecast by Type (2026-2033)
12.1.1 Global Forecasted Sales of Single Injection Hyaluronic Acid Viscosupplement by Type (2026-2033)
12.1.2 Global Single Injection Hyaluronic Acid Viscosupplement Market Size Forecast by Type (2026-2033)
12.1.3 Global Forecasted Price of Single Injection Hyaluronic Acid Viscosupplement by Type (2026-2033)
12.2 Global Single Injection Hyaluronic Acid Viscosupplement Market Forecast by Application (2026-2033)
12.2.1 Global Single Injection Hyaluronic Acid Viscosupplement Sales (K Units) Forecast by Application
12.2.2 Global Single Injection Hyaluronic Acid Viscosupplement Market Size (M USD) Forecast by Application (2026-2033)
13 Conclusion and Key Findings

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