Market Research Logo

Global Cell Free DNA Isolation and Extraction Market- Focus on 25 country Analysis, Competitive Landscape, Applications (NIPT, Oncology, etc.), Product and Platform- Analysis and Forecast, 2018-2026

Global Cell Free DNA Isolation and Extraction Market- Focus on 25 country Analysis, Competitive Landscape, Applications (NIPT, Oncology, etc.), Product and Platform- Analysis and Forecast, 2018-2026

Cell-free DNA are non-encapsulated DNA that enters the bloodstream during apoptosis or necrosis. This cell-free DNA is cleared by macrophages during normal body functioning, but overproduction of cells during cancer produces extra cfDNA in the blood. The CfDNA are found in blood, plasma, serum, or other body fluids and holds clinical significance in diagnosis, monitoring, and detection of various non-invasive diseases. The cfDNA is a screening method for tumors and other fetal DNA studies, they are challenging to extract as they are found in small quantities, and so reliable and consistent methods are required to isolate the less abundant cell-free DNA with higher sensitivity as they have a half-life of about two hours. The global cfDNA extraction and isolation industry is a multi-billion-dollar market which consists of multitudinous companies involved in the development of cfDNA extraction/isolation kits and automated instruments based on various sequencing platforms such as NGS and PCR to bolster the increasing demand for non-invasive screening tests and procedures.

cfDNA extraction and isolation products include extraction/isolation kit, automated instruments, and other consumables to improve the overall non-invasive screening process efficiency. Cell-free DNA testing is a new and efficient technology in which free-flowing DNA fragments from a liquid sample such as saliva, urine, and blood from patients are analyzed to screen a condition or disease. Cell-free DNA testing is essential solutions for the medical diagnostic companies that are facing increasing level of demand for high productivity and cost reduction. The recent advances in Cell-free DNA testing have paved the way for the development of multiple advanced technologies to aid in the battle against cancer and various other diseases including genetic and infectious diseases. The advent of screening procedures such as NIPT and liquid biopsy with improved efficiency of screening results are the most prominent factors facilitating the growth of Cell-free DNA testing in the medical diagnostic industry. Furthermore, these advanced testing procedures have also enabled the companies in the medical diagnostic industry to meet the regulatory compliance as well as manage their profit margins and remain competitive in the market.

The purpose of this study is to gain a holistic view of the Cell-free DNA testing market in terms of various influencing factors, such as recent trends and technological advancements. The scope of this report constitutes an in-depth study of the global Cell-free DNA testing market, including a thorough analysis of the products across different regions. The market has been segmented into ‘product’, ‘platform’, ‘application ‘and ‘regions’. The report presents the reader with an opportunity to unlock comprehensive insights concerning the market and helps in forming well informed strategic decisions. The research uncovers some of the substantial parameters that must be taken into consideration before entering the market.

This research report aims at answering various aspects of the global Cell-free DNA testing market with the help of the key factors driving the market, restraints that can inhibit the overall market growth, and the current growth opportunities that are going to shape the future trajectory of the market expansion. The report includes an in-depth examination of the key ecosystem players and key strategies and developments taking place in this market. Moreover, the report includes chapters on market dynamics (market drivers, opportunities and challenges) and industry analysis as well.

The research study considers the market share analysis for a comprehensive understanding of the global Cell-free DNA testing market and assesses the factors governing the same. Growth share matrix and detailed pricing analysis have been included in the report. The market by region has been further sub-segmented into various countries, and in each sub-segment, the key market trends, list of the key players, and the recent developments that have taken place have been discussed.

The answers to the following key questions can be derived from this report:

  • What are the major market drivers, challenges and opportunities in the Cell-free DNA testing market?
  • What was the market value of the leading segments and sub-segments of the global Cell-free DNA testing in 2016?
  • How will each segment of the global Cell-free DNA testing market grow during the forecast period and what will be the revenue generated by each of the segments by the end of 2026?
  • What are the influencing factors that may affect the market share of the key players in Cell-free DNA testing market?
  • How will the Cell-free DNA testing industry evolve during the forecast period 2018- 2026?
  • What are the key developmental strategies that are being implemented by the key players to sustain in this market?
  • What is the market share of each of the companies by NIPT test providers?
  • What is the growth-share matrix of each of the companies by NIPT test providers?
  • Who are the key players in the Cell-free DNA extraction/isolation kits market and what are their contributions?
  • What are the major benefits of the implementation of Cell-free DNA testing in the different field of applications including cancer diagnosis, prenatal testing, and several other chronic diseases?
  • What is the scope of Cell-free DNA testing in the emerging economies of the Asia Pacific and Latin America?
  • What is the scope for expansion by the key players of the Cell-free DNA testing market in the Asia Pacific and Latin America?
The key players who have been contributing significantly to the Cell-free DNA testing market include Agilent Technologies, Inc., Berry Genomics, BGI Diagnostics, BioCAT GmbH, F. Hoffmann-La Roche AG, GATC Biotech AG., Illumina, Inc., Laboratory Corporation of America, LifeCodexx AG, Merck KGaA, Natera Inc., NIPD Genetics, Norgen Biotek Corp., PreAnalytiX GmbH, Premaitha Health Plc, QIAGEN, Quest Diagnostics, SeraCare Life Sciences, Inc., STRATEC Biomedical AG, Thermo Fisher Scientific, AccuBioMed, Aline Biosciences, BioChain, Bioo Scientific Corporation, COVARIS, INC., Epigentek Group Inc., NeoGenStar LLC, Omega Bio-tek, Inc, Promega Corporation, System Biosciences, LLC., and STRECK, INC., among others.


Executive Summary
1 Market Overview
1.1 Introduction
1.2 Early Discovery and Applications of cfDNA
1.3 Properties of cfDNA
1.4 Biological Role of cfDNA
1.5 Extraction of Circulating cfDNA
1.6 Application of Circulating cfDNA
1.7 Addressable Market Size and Growth Potential
1.8 Recent Historical Trends 2013-2016 (Parent Market: Genomics)
1.9 Recent Historical Trends 2013-2016 (cfDNA)
2 Market Dynamics
2.1 Promoting and Inhibiting Factors of cfDNA Market Growth
2.2 Market Drivers
2.3 Market Restraints
2.4 Market Opportunities
3 Competitive Landscape
3.1 Key Develoments and Stratgies
3.2 Market Share Analysis by Company (2015 and 2016)
3.3 Value Chain Analysis
4 Pricing Analysis
4.1 cfDNA Extraction Kits Pricing Analysis
5 Global Cell Free DNA Extraction and Isolation Market, by Product
5.1 Analysis
5.2 Cell Free DNA Extraction and Isolation Kits
5.3 Cell Free DNA Automated Instruments
5.4 Consumables
6 Global Cell Free DNA Extraction and Isolation Market, by Platform
6.1 Introduction
6.2 Next Generation Sequencing
6.3 Polymerase Chain Reaction (PCR)
6.4 Others
7 Global Cell Free DNA Extraction and Isolation Market, by Applications
7.1 Overview
7.2 Non-Invasive Prenatal Testing (NIPT)
7.3 Oncology
7.4 Transplant Rejection and Other Disease Condition
7.5 Others
8 Global Cell Free DNA Extraction and Isolation Market, by Region
8.1 Overview
8.2 North America
8.2.1 U.S.
8.2.2 Canada
8.3 Europe
8.3.1 Germany
8.3.2 France
8.3.3 U.K.
8.3.4 Italy
8.3.5 Spain
8.3.6 Denmarrk
8.3.7 Others
8.4 Asia Pacific
8.4.1 China
8.4.2 India
8.4.3 Singapore
8.4.4 Japan
8.4.5 Others
8.5 Latin America
8.5.1 Brazil
8.5.2 Mexico
8.5.3 Others
8.6 Rest of the World
9 Company Profiles
9.1 Overview
9.2 Agilent Technologies, Inc.
9.3 AccuBioMed
9.4 Aline Biosciences
9.5 Berry Genomics
9.6 BioChain
9.7 Bioo Scientific Corporation
9.8 BGI Diagnostics
9.9 BioCAT GmbH
9.1 Epigentek Group Inc.
9.11 F. Hoffmann-La Roche AG
9.12 GATC Biotech AG.
9.13 Illumina, Inc.
9.14 Laboratory Corporation of America
9.15 LifeCodexx AG
9.16 Merck KGaA
9.17 Natera Inc.
9.18 NIPD Genetics
9.19 Norgen Biotek Corp
9.2 PreAnalytiX GmbH
9.21 Premaitha Health Plc
9.22 GATC Biotech AG.
9.23 Illumina, Inc.
9.24 Laboratory Corporation of America
9.25 QIAGEN
9.26 Quest Diagnostics
9.27 SeraCare Life Sciences, Inc.
9.28 STRATEC Biomedical AG
9.29 Thermo Fisher Scientific
9.3 NeoGenStar LLC
9.31 Omega Bio-tek, Inc
9.32 Promega Corporation
9.33 System Biosciences, LLC.
9.34 STRECK, INC.
10 Report Scope & Methodology
10.1 Scope of the Report
10.2 Global Cell Free DNA Extraction and Isolation Market Segmentation
10.3 Research Methodology
10.3.1 Primary Research
10.3.2 Secondary Research
10.3.3 Key Data Points from Primary Sources
10.3.4 Key Data Points from Secondary Sources
10.3.5 Data Triangulation
10.3.6 Top-Down Approach (Segment wise Analysis)
10.3.7 Bottom-Up Approach (Segmental Analysis)
10.4 Assumptions and Limitations
10.5 Data and Prediction Modelling
List of Tables
Global cfDNA Extraction/Isolation Market
Advanced Technologies Employed for Circulating cell-free DNA
Market Share Analysis
cfDNA Extraction Kits Pricing Analysis
Global cfDNA Extraction/Isolation Market by Product ($Million)
By Product : Extraction/Isolation Kits: Key Players
List of Some Commercially Available Isolation Kits
Sales of Key Isolation Kits ($Million)
cfDNA Extraction/Isolation Kits Market by Method ($Million)
cfDNA Extraction/Isolation Kits Market by Method (Sample Processed, In Thousand Units)
By Product : Automated Instruments: Key Players
By Product : Consumables: Key Players
Product Analysis
Global cfDNA Extraction/Isolation Market by Platform ($Million)
Global cfDNA Extraction/Isolation Market by Platform (Sample Volume in Thousand)
Comparison between Next Generation Sequencing (NGS) and Polymerase Chain Reaction (dPCR)
Global cfDNA Extraction/Isolation Market by Application ($Million)
Global cfDNA Extraction/Isolation Market by Application (Sample Volume in Thousand)
Growth Share Matrix by cfDNA NIPT Test Providers
Global cfDNA Extraction/Isolation Market by Region ($Million)
Global cfDNA Extraction/Isolation Market by Region (Sample Volume in Thousand)
Key Players of North America
Key Players of Europe
Key Players of Asia Pacific
Key Players of Latin America and RoW
Latin America and RoW Market
List of Qiagen products for cfDNA
Thermo Fisher Scientific: Product Portfolio
List of Figures
Global cfDNA Extraction and Isolation Market, 2016 and 2026
Global cfDNA Extraction and Isolation Market Value & Forecast, 2016–2026 (US$ Million)
Global cfDNA Extraction/Isolation Market Segmentation (Value)
Global cfDNA Extraction/Isolation Volume by Extraction Technology
Global cfDNA Extraction/Isolation Share by Extraction Technology, 2016
Global cfDNA Extraction/Isolation Share by Extraction Technology, 2026
Market Penetration of Automation Systems (Area Represent the Penetration Share), 2016
Global cfDNA Extraction/Isolation Market by Application (US$ Mn), 2016-2026
Global cfDNA Extraction/Isolation Market by Application, 2016
Global cfDNA Extraction/Isolation Market by Application, 2026
Global cfDNA Extraction/Isolation Market by Application (US$ Mn)
Global cfDNA Extraction/Isolation Market by End-User, 2016
Global cfDNA Extraction/Isolation Market by End-User, 2026
Global cfDNA Extraction/Isolation Market by Platform/technique (US$ Mn)
Global cfDNA Extraction/Isolation Market by Platform/technique, 2016
Global cfDNA Extraction/Isolation Market by Platform/technique (US$ Mn), 2026
Global cfDNA Extraction/Isolation Market by region, 2016
Global cfDNA Extraction/Isolation Market, by Region 2023
Global cfDNA Extraction/Isolation Market Growth Rate by Region
Global cfDNA Extraction/Isolation Market, 2016-2026 (US$ Mn)
Global cfDNA Extraction/Isolation Market, 2016-2026 (Sample processed Volume)
Global cfDNA Extraction/Isolation Market by Application ($Million)
Global cfDNA Extraction/Isolation Market by Application (Test Volume, Units)
Global cfDNA Extraction/Isolation Market ($Million)
Total cfDNA Isolation Volume by Major Countries ($Million), 2016 & 2026
Global cfDNA Extraction/Isolation Market by Region 2016
Global cfDNA Extraction/Isolation Market by Region 2023
North America cfDNA Extraction/Isolation Market Growth Pattern, 2016-2026
Europe cfDNA Extraction/Isolation Market Growth Pattern, 2016-2027
Asia Pacific cfDNA Extraction/Isolation Market Growth Pattern, 2016-2026
Latin America cfDNA Extraction/Isolation Market Growth Pattern, 2016-2026
Global Research Genomics Market, 2016 (US$ Bn)
Global Clinical Genomics Market, 2016 (US$ Bn)
Recent Historical Trends 2013-2016 (cfDNA): Prenatal Testing
Company/Laboratory Offering cfDNA Test (NIPT and Cancer)
cfDNA Based Test Volume, 2011-2026
Market Share Analysis, 2015
Market Share Analysis, 2016
Value Chain
Global cfDNA extraction/isolation market: By Product
Global cfDNA extraction/Isolation Market by Products ($Million)
Global cfDNA Extraction/Isolation Market Share by Product 2016
Global cfDNA Extraction/Isolation Market Share by Product 2026
Global cfDNA Extraction/Isolation Kits Market ($Million)
Global cfDNA Automated Extraction System Market ($Million)
Global cfDNA Other Consumables Market ($Million)
Global Magnetic bead-based cfDNA Extraction Kits Market ($Million)
Global Magnetic bead-based cfDNA Extraction Kits Market (In Thousand Units)
Global Column based cfDNA Extraction Kits Market (US$ Mn)
Global Column based cfDNA Extraction Kits Market (In Thousand Units)
Global Other cfDNA Extraction Kits Market (US$ Mn)
Global Other cfDNA Extraction Kits Market (In Thousand Units)
Global Automated Instruments cfDNA Extraction System Market ($Million)
Global Consumables cfDNA Extraction Market ($Million)
Global cfDNA Extraction/Isolation Market ($Million)
Global cfDNA Extraction/Isolation Market (Sample Volume, Thousand Units)
Global cfDNA Extraction Isolation Market Growth Rate by Revenue
Global cfDNA Extraction Isolation Market Growth Rate by Volume
Growth Share Matrix by Platform, 2016
cfDNA NGS Market, 2016-2026 ($Million)
cfDNA NGS Market, 2016-2026 (Test Volume, in Thousand Units)
rPCR and Multiplexed PCR Based cfDNA Processing Volume (Thousand Units)
rPCR and Multiplexed PCR Based cfDNA Processing Revenue
qPCR Based cfDNA Processing Revenue
qPCR Based cfDNA Processing Volume (Thousand Units)
dPCR Based cfDNA Processing Volume (Thousand Units)
dPCR Based cfDNA Processing Revenue
cfDNA Quantification Breakdown by Type of PCR, 2016
cfDNA Quantification Breakdown by Type of PCR, 2026
Global cfDNA Extraction/Isolation Market by Application ($Million)
Global cfDNA Extraction/Isolation Market by Application, 2016
Global cfDNA Extraction/Isolation Market by Application, 2026
Global Oncology cfDNA Extraction/Isolation Market ($Million)
Global Oncology cfDNA Extraction/Isolation Market (Test Volume, Thousand Units)
Cobas EGFR Mutation Test v2 Volume Growth Projection
Global NIPT cfDNA Extraction/Isolation Market ($Million)
Global NIPT cfDNA Extraction/Isolation Market (Test Volume, Thousand Units)
Global NIPT cfDNA Market Share Analysis (by Test Volume), 2016
Global NIPT cfDNA Market Share Analysis (by Test Volume), 2026
Growth Share Matrix by cfDNA NIPT Test Providers
Global NIPT Market Revenue by Region ($Million)
Global NIPT Test Volume by Region (Units)
Global Other cfDNA Extraction/Isolation Market ($Million)
Global Other cfDNA Extraction/Isolation Market (Test Volume, Thousand Units)
Global cfDNA Extraction/Isolation Market by Region, 2016
Global cfDNA Extraction/Isolation Market by Region, 2026
North America cfDNA Extraction/Isolation Market ($Million)
North America cfDNA Extraction/Isolation Market
U.S. cfDNA Extraction Kits Market (US$ Mn)
U.S. cfDNA Extraction Kits Market (In Thousand Units)
Canada cfDNA Extraction Kits Market (US$ Mn)
Canada cfDNA Extraction Kits Market (In Thousand Units)
U.K. cfDNA Extraction Kits Market ($Million)
U.K. cfDNA Extraction Kits Market (In Thousand Units)
Germany cfDNA Extraction Kits Market ($Million)
Germany cfDNA Extraction Kits Market (In Thousand Units)
France cfDNA Extraction Kits Market ($Million)
France cfDNA Extraction Kits Market (In Thousand Units)
Rest of Europe cfDNA Extraction Kits Market ($Million)
Rest of Europe cfDNA Extraction Kits Market (In Thousand Units)
Asia Pacific cfDNA Extraction/Isolation Market ($Million)
China cfDNA Extraction Kits Market ($Million)
China cfDNA Extraction Kits Market (In Thousand Units)
Japan cfDNA Extraction Kits Market ($Million)
Japan cfDNA Extraction Kits Market (In Thousand Units)
India cfDNA Extraction Kits Market ($Million)
India cfDNA Extraction Kits Market (In Thousand Units)
Agilent Technologies, Inc.: Product Portfolio
Agilent Technologies, Inc.: Overall Financials (2014-2016)
Agilent Technologies, Inc.: Revenue by Business Segment (2014-2016)
Agilent Technologies, Inc.: Revenue by Region (2014-2016)
Agilent Technologies, Inc.: SWOT Analysis
Berry Genomics: Product Portfolio
Berry Genomics: SWOT Analysis
BGI Diagnostics: Product Portfolio
BGI Diagnostics: SWOT Analysis
BioCAT GmbH: Product Portfolio
BioCat GmbH: SWOT Analysis
F. Hoffmann-La Roche AG: Product/Service Mapping
F. Hoffmann-La Roche AG: Net Revenue (2014-2016)
F. Hoffmann-La Roche AG: Revenue by Region (2014-2016)
F. Hoffmann-La Roche AG: Revenue by Divisions (2014-2016)
F. Hoffmann-La Roche AG: : Revenue By Diagnostics Sub-division (2014-2016)
F. Hoffmann-La Roche AG: SWOT Analysis
GATC Biotech AG: Product Portfolio
GATC Biotech AG: SWOT Analysis
Illumina, Inc.: Product Portfolio
Illumina, Inc.: Overall Financials (2014-2016)
Illumina, Inc.: Net revenue, Product revenue and Service revenue (2014-2016)
Illumina, Inc.: Revenue by Region, (2014-2016)
Illumina, Inc.: SWOT Analysis
Laboratory Corporation of America: Product/Service Portfolio
Laboratory Corporation of America: Overall Financials (2014-2016)
Laboratory Corporation of America: Revenue by Business Segment (2014-2016)
Laboratory Corporation of America: Geographic Distribution of Net Revenues (2016)
Laboratory Corporation of America: SWOT Analysis
LifeCodexx AG: Product Portfolio
LifeCodexx AG: SWOT Analysis
Merck KGaA: Product/Service Portfolio (Sigma-Aldrich, a Subsidiary of Merck)
Merck KGaA: Overall Financials (2014-2016)
Merck KGaA: Net Revenue by Business Segments, (2014-2016)
Merck KGaA: Revenue by Region (2014-2016)
Merck KGaA: SWOT Analysis
Natera Inc.: Product/Service Portfolio
Natera Inc.: Overall Financials (2014-2016)
Natera Inc.: Revenue by Region (2014-2016)
Natera Inc.: SWOT Analysis
NIPD Genetics: Product Portfolio
NIPD Genetics: SWOT Analysis
Norgen Biotek Corp.: Product Portfolio
Norgen Biotek Corp.: SWOT Analysis
PreAnalytiX GmbH: Product Portfolio
PreAnalytiX GmbH: SWOT Analysis
Premaitha Health Plc: Product Portfolio
Premaitha Health Plc: Overall Financials (2014-2016)
Premaitha Health Plc: Revenue by Region (2014-2016)
Premaitha Health Plc: SWOT Analysis
QIAGEN: Product and Service Portfolio
QIAGEN: Overall Financials (2014-2016)
QIAGEN: Net Revenue by Business Segment (2014-2016)
QIAGEN: Net Revenue by Region (2014-2016)
QIAGEN: SWOT Analysis
Quest Diagnostics: Product Portfolio
Quest Diagnostics: Overall Financials (2014-2016)
Quest Diagnostics: Revenue by Business Segment (2014-2016)
Quest Diagnostics: Revenue by DIS segment (2014-2016)
Quest Diagnostics: SWOT Analysis
SeraCare Life Sciences, Inc.: Product Portfolio
SeraCare Life Sciences, Inc.: SWOT Analysis
STRATEC Biomedical AG: Product Portfolio (Stratec Molecular GmbH, a subsidiary of Stratec Biomedical AG)
Stratec Biomedical AG: Overall Financials (2014-2016)
Stratec Biomedical AG: Revenue by Region (2014-2016)
Stratec Biomedical AG: Revenue by Business Segment (2014-2016)
Stratec Biomedical AG: Revenue by Business Segment 2014
STRATEC Biomedical AG: SWOT Analysis
Thermo Fisher Scientific: Overall Financials (2014-2016)
Thermo Fisher Scientific: Net Revenue by Business Segment (2014-2016)
Thermo Fisher Scientific: Net Revenue by Region (2014-2016)
Thermo Fisher Scientific: SWOT Analysis
AccuBioMed: Product Portfolio
Aline Biosciences: Product Portfolio
BioChain: Product Portfolio
Bioo Scientific Corporation: Product Portfolio
Covaris, Inc.: Product Portfolio
Epigentek Group Inc.: Product Portfolio
NeoGenStar LLC: Product Portfolio
Omega Bio-tek, Inc.: Product Portfolio
Promega Corporation: Product Portfolio
System Biosciences, LLC: Product Portfolio

Download our eBook: How to Succeed Using Market Research

Learn how to effectively navigate the market research process to help guide your organization on the journey to success.

Download eBook

Share this report