
Alopecia Areata (AA)
Description
MarketVue®: Alopecia Areata
The MarketVue®: Alopecia Areata market landscape report combines primary (KOL interviews and survey data) and secondary market research to empower strategic decision-making and provide a complete view of the market.Every MarketVue® includes a disease overview, epidemiology (US and EU5), current treatment, unmet needs, pipeline and access and reimbursement chapter.
Topics covered in this report:
• Disease overview: Review the disease pathophysiology and potential druggable targets
• Epidemiology: Understand prevalence, diagnosed and drug-treated prevalence of the population and key market segments
• Current treatment: Understand the treatment decision tree and strengths and weaknesses of current on-label and off-label treatment
• Unmet needs: Identify opportunities to address treatment or disease management gaps
• Pipeline analysis: Compare current and emerging therapy clinical development strategy; their performance on efficacy, safety, and delivery metrics; and their potential to address unmet needs
• Value and access: Review the evidence needed to assess and communicate value to key stakeholders (e.g., providers, payers, regulators) and learn what competitors have done or are doing
Methodology:
Research for the MarketVue®: Alopecia Areata report is supported by 6 qualitative interviews with key opinion leaders, a quantitative survey with 25 U.S. physicians and secondary research.
Geographies covered:
United States plus epidemiology for EU5 (France, Germany, Italy, Spain, United Kingdom)
Key companies mentioned:
• Eli Lilly
• Incyte
• Pfizer
• Concert Pharmaceuticals
• AbbVie
• Suzhou Zelgen Biopharmaceuticals
• Legacy Healthcare
• Throne Biotechnologies
• Arena Pharmaceuticals
• Reistone Biopharma
• Bioniz Therapeutics / Equillium
Key drugs mentioned:
• Injectable and topical steroids
• Minoxidil (Rogaine)
• Methotrexate (Trexall, Rheumatrex)
• Diphencyprone (DPCP)
• Tacrolimus (Prograf , Protopic)
• Baricitinib (Olumiant)
• Tofacitinib (Xeljanz)
• Dupilumab (Dupixent)
• Ruxolitinib (Jakafi, Opzelura)
• Adalimumab (Humira)
• Upadacitinib (Rinvoq
• Ritlecitinib (Litfulo)
• Coacillium
• Stem Cell Educator (SCE) therapy
• Etrasimod (Velsipity)
• SHR0302
• BNZ-1
• Jaktinib
Please note: the online download version of this report is for a global site license.
Table of Contents
27 Pages
- 1. DISEASE OVERVIEW
- An autoimmune condition that causes hair to fall out
- Table 1.1. Types of alopecia areata
- 2. EPIDEMIOLOGY & PATIENT POPULATIONS
- Disease definition
- Figure 2.1. G6 prevalent cases of alopecia areata by region
- Table 2.1 Prevalent alopecia areata population in the US and EU5
- Patchy alopecia areata is the predominate form of the disease
- Figure 2.2. Alopecia areata population by severity
- Figure 2.3. Dermatologist-reported key population dynamics in alopecia areata
- 3. CURRENT TREATMENT
- Overview
- Figure 3.1. Treatment goals for alopecia areata
- Figure 3.2. U.S. dermatologist alopecia areata patient load
- Standard of care
- Figure 3.3. U.S. Dermatologist-reported patient share of current treatments in alopecia areata
- Table 3.1. Upsides and downsides of currently available treatment options
- Figure 3.4. Treatment algorithm for the management of alopecia areata
- In their own words: Dermatologists’ insights on alopecia areata treatments
- Dermatologists hope JAK inhibitors will become the first-approved class for alopecia area
- Table 3.2. Must-know alopecia areata treatment dynamics for now and the future
- The burden of disease in alopecia areata is not just cosmetic but also psychosocial in nature
- Figure 3.5. Dermatologists’ rating of the impact of alopecia areata on patients
- In their own words: More of dermatologists’ thoughts on the burden of alopecia areata
- Dermatologists are excited about JAK inhibitors but the pipeline is weak for other MOAs
- Figure 3.6. Timeline of alopecia areata market evolution
- 4. UNMET NEED
- Overview
- Figure 4.1. Top unmet needs in alopecia areata
- Figure 4.2. Dermatologist-reported unmet needs in alopecia areata
- In their own words: Dermatologists opinion on top unmet needs for alopecia areata
- Figure 4.3. Percentage of alopecia areata patients in which U.S. dermatologists are dissatisfied with current therapies
- Figure 4.4. U.S. dermatologists view on the need for new treatments in dermatology conditions
- Alopecia areata patient insights on unmet needs
- Figure 4.5. Key takeaways from the FDA’s “Voice of the Patient” on alopecia areata
- 5. PIPELINE ANALYSIS
- Clinical trials for alopecia areata are focused on promoting scalp hair regrowth
- Figure 5.1. Number of emerging therapies addressing unmet needs in alopecia areata
- Figure 5.2. Percentage of dermatologists rating target as “promising” for treating alopecia areata
- Dermatologists are cautious but not deterred over FDA warning for JAK inhibitors
- Summary of clinical-stage emerging alopecia areata therapies
- Figure 5.3. Phase 3 results for Eli Lilly/Incyte’s baricitnib in severe alopecia areata
- Table 5.1. Emerging alopecia areata therapies
- 6. VALUE & ACCESS
- Overview
- Table 6.1. Alopecia areata current therapy pricing, U.S.
- Reimbursement for alopecia areata drugs will be met with hurdles
- Table 6.2. ICD-10 diagnosis codes for alopecia areata
- Figure 6.1. Reimbursement and access considerations for emerging therapies in alopecia areata
- Figure 6.1. Alopecia areata patients by insurance type in the U.S.
- Figure 6.2. Alopecia areata patients by insurance type in the U.S.
- Figure 6.3. Key considerations for building a market access strategy in alopecia areata
- 7. METHODOLOGY
- Primary market research approach
- Epidemiology methodology
- Disease definition
- Prevalence estimates
Pricing
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