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Gene Expression Profiling Markets

Parts of the gene expression analysis market continue to develop in a somewhat predictable manner, whereas other segments are becoming increasingly complex and volatile. The main products—microarrays and RT-PCR—continue to gain widespread acceptance and to see revenues grow rapidly. However, different products and applications are increasingly being introduced, making the market more fragmented as well as unpredictable. In terms of application, too, the landscape is shifting. Although life-science research is still the dominant application, the clinical diagnostics and prognostics market is also becoming a reality.

This new study on the gene expression analysis market reviews the major technologies being employed, including:

  • Alternative Splicing; Splice Variant Microarrays
  • Cap Analysis of Gene Expression (CAGE)
  • Comparative Genomic Hybridization (CGH)
  • ChIP-on-chip
  • DNA Microarrays
  • Gene Trapping
  • Methylation, Other Epigenetic Analysis
  • MicroRNA
  • Real-time PCR (RT-PCR)
  • RNAse Protection Assays
  • Serial Analysis of Gene Expression (SAGE)
  • Tissue Arrays / Microarrays
  • Transcript Analysis with Affinity Capture (TRAC)

In addition to comprehensive review of the products on the market from the major suppliers, each of the main applications of gene expression technologies is also reviewed, including:

  • Biomarkers,
  • Pharmacogenetics / Pharmacogenomics,
  • Infectious Disease Research,
  • Cancer Diagnostics and Prognostics, and
  • Diagnosis and Prognosis of Other Diseases

The report provides a complete analysis of the market, including historical data on the market for RT-PCR and microarrays, instruments, and reagents. The report also forecasts revenues through 2012 in the segment and provides growth rates for each of the coming years, a complete regional breakdown of revenues, and revenue detail on the dominant player by region. A thorough competitive analysis includes revenue and market share of the top vendors. Detailed profiles of the following competitors are also included:

  • Affymetrix
  • Agilent Technologies
  • Applied Biosystems
  • Beckman Coulter
  • Combimatrix
  • Illumina
  • Roche Applied Science

Gene Expression Profiling Markets also details the business, regulatory, academic, and research trends in the market, providing comprehensive information on consortia, standardization efforts, and scores of recent deals in the sector.

License Note: Kalorama Information's listed default price on its information products reflects a single user license only. Purchasing a departmental license (up to 10 users at one location) or a global site license (entire company) permits multiple individuals in the company to benefit from this resource.


  • Executive Summary
    • INTRODUCTION AND SUMMARY
    • BACKGROUND AND DEFINITIONS
      • Alternative Splicing; Splice Variant Microarrays
      • Cap Analysis of Gene Expression (CAGE)
      • Comparative Genomic Hybridization (CGH)
      • ChIP-on-chip
      • DNA Microarrays
      • Gene Trapping
      • Methylation, Other Epigenetic Analysis
      • MicroRNA
      • Real-time PCR (RT-PCR)
      • RNAse Protection Assays
      • Serial Analysis of Gene Expression (SAGE)
      • Tissue Arrays / Microarrays
      • Transcript Analysis with Affinity Capture (TRAC)
  • Applications
    • BIOMARKERS
    • PHARMACOGENETICS /PHARMACOGENOMICS
    • CANCER DIAGNOSIS,PROGNOSIS,SUB-CLASSIFICATION
      • Breast Cancer
      • Esophageal Cancer
      • Head and Neck Cancer
      • Kidney Cancer
      • Leukemia
      • Lung Cancer
      • Lymphoma
      • Oral Cancer
      • Ovarian Cancer
      • Prostate Cancer
      • Pancreatic Cancer
      • Multiple, General
    • INFECTIOUS DISEASE RESEARCH
      • Table Areas Using Gene Expression Profiles in Infectious Disease Research
    • DIAGNOSTIC /PROGNOSTIC TECHNOLOGIES AND APPLICATIONS
      • Agendia
      • DakoCytomation
      • ChondroGene
      • Genomic Health
  • Industry, Technology, and Regulatory Trends
    • INDUSTRY TRENDS
      • Gene Expression Profiling Becoming Established Tool
      • Various Types of Small RNA Gaining Importance
      • Gene Expression Analysis Moves Gradually into Diagnostics
      • Quality Control of RNA Samples Becoming Standard Process
    • TECHNOLOGY TRENDS
      • New Technologies Entering Gene Expression Analysis Market
      • Questions Remain Regarding Housekeeping and Reference Genes
      • Probe Length Still Varying Greatly Between Vendors
      • Amplification Remains Key Aspect of Experiments
      • Sample Preparation Becoming High Priority
    • REGULATORY TRENDS
      • March 2004 - Critical Path Initiative
      • March 2005 - "Guidance for Industry - Pharmacogenomic Data Submissions"
      • April 2005 - "Drug-Diagnostic Co-Development Concept Paper"
      • March 2006 - Critical Path Opportunities List
        • Table Critical Path Opportunities List (March 2006)
      • November 2006 - "Recommendations for the Generation and Submission of Genomic Data"
      • August 2007 - "Pharmacogenomic Data Submissions - Companion Guidance"
  • Products and Services for Research Applications
    • RESEARCH PRODUCTS
      • Affymetrix
      • Agilent Technologies
      • Applied Biosystems
      • Ambion (an Applied Biosystems Business)
      • Beckman Coulter
      • Bio-Rad
      • Experion Automated Electrophoresis System
      • Biosearch Technologies
      • Combimatrix
      • Epicentre Biotechnologies
      • Exiqon
      • febit
      • Illumina
      • Kreatech Biotechnology
      • Marligen Biotechnologies
      • Panomics
      • Roche Applied Science
      • Stratagene (Agilent)
      • SideStep and SideStep II Products and Kits
    • PRODUCTS -SELECTED LIST
      • Table Selected Gene Expression Analysis Products
      • Next-Generation Sequencers
        • Table Selected List of Next-Generation Sequencer Products and Technologies
      • Diagnostic, Prognostic, Theranostic Products
        • Table Selected List of Next-Generation Sequencer Products and Technologies
    • SOFTWARE AND SERVICES
      • Althea Technologies
      • Gene Logic [Ocimum]
      • Genomatix Software GmbH
      • Iconix Biosciences
        • Table Selected List of Software Products Available for the Gene Expression Analysis Market
  • Consortia, Initiatives, Standardization, Deals
    • CRITICAL PATH INSTITUTE
    • EXTERNAL RNACONTROLS CONSORTIUM (ERCC)
    • MICROARRAY QUALITY CONTROL (MAQC) PROJECT
    • MINIMUM INFORMATION ABOUT A MICROARRAY EXPERIMENT (MIAME)
    • NIH ROADMAP FOR MEDICAL RESEARCH
    • INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARDS (CTSA'S)PROGRAM (OCTOBER 2005)
    • TOXICOGENOMICS RESEARCH CONSORTIUM
    • OTHER EXPERIMENTS TO ASSESS COMPARABILITY, REPRODUCIBILITY
      • Table Selected Deals Taking Place in the Gene Expression Analysis Market
  • Market Analysis
    • HISTORICAL
      • Affymetrix as Bellwether for Microarray Segment
      • Applied Biosystems as Bellwether for qRT-PCR Segment
        • Table Forcasted Revenues in the Gene Expression Market (2006-2012)
        • Table Growth Rates Forecast (2006-2012)
    • ASSUMPTIONS
      • Table Gene Expression Product Revenues Regional Breakdown and Trend 2006
      • Table Regional Shares of Affymetrix's Overall Revenues 2001-2006
    • COMPETITIVE ANALYSIS
      • Introduction
        • Table Estimated Revenues and Market Shares for the Top Vendors in the Gene Expression Analysis
    • CORPORATE PROFILES
      • Affymetrix
      • Agilent Technologies
      • Applied Biosystems
      • Beckman Coulter
      • Combimatrix
      • Illumina
      • Roche Applied Science
  • Challenges & Strategic Recommendations
    • CHALLENGES
      • Next-Generation Sequencers Create Wild Card
      • Affymetrix Dominance Decreasing But Still Significant
      • Market Complicated by New Gene Expression & Regulation Analysis Products
      • Pharmaceutical Industry Tightening Budgets, Scrutinizing Technologies
      • Regulations for Diagnostics Still Shaking Out
      • RT-PCR Competing Strongly With Microarrays
      • SNP Analysis and Copy Number Variation Easier and Popular
      • Growth Threatened by Industrialization, Commoditization
      • Resistance Towards Diagnostics Using Multiple Markers
      • Data Analysis and Management Still Hindering End-Users
      • Multiplexing Limitations of Real Time Quantitative PCR
      • Longer Term Prospects Threatened by Proteomics, Metabolomics
    • STRATEGIC RECOMMENDATIONS
      • Diversify Into Multiple Aspects, Applications
      • Partner With Market Leaders
      • Provide Software Tools for Comparison Across Platforms, Techniques
      • Investigate Intellectual Property and Licensing Possibilities

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