
Systemic Mastocytosis Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Description
Systemic Mastocytosis Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Summary
Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Systemic Mastocytosis - Drugs In Development, 2022, provides an overview of the Systemic Mastocytosis (Gastrointestinal) pipeline landscape.
Systemic mastocytosis is a disorder where mast cells are abnormally increased in multiple organs including the bone marrow. Symptoms include shortness of breath, low blood pressure, hives and swelling, itching, diarrhea, headache, flushing and musculoskeletal pain. Treatment includes antihistamines and more aggressive forms of Systemic mastocytosis require interferon or chemotherapeutic agents.
Report Highlights
Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Systemic Mastocytosis - Drugs In Development, 2022, provides comprehensive information on the therapeutics under development for Systemic Mastocytosis (Gastrointestinal), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.
The Systemic Mastocytosis (Gastrointestinal) pipeline guide also reviews of key players involved in therapeutic development for Systemic Mastocytosis and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Filing rejected/Withdrawn, Phase III, Phase II, Phase I and Preclinical stages are 1, 1, 4, 2 and 3 respectively.
Systemic Mastocytosis (Gastrointestinal) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.
Scope
Summary
Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Systemic Mastocytosis - Drugs In Development, 2022, provides an overview of the Systemic Mastocytosis (Gastrointestinal) pipeline landscape.
Systemic mastocytosis is a disorder where mast cells are abnormally increased in multiple organs including the bone marrow. Symptoms include shortness of breath, low blood pressure, hives and swelling, itching, diarrhea, headache, flushing and musculoskeletal pain. Treatment includes antihistamines and more aggressive forms of Systemic mastocytosis require interferon or chemotherapeutic agents.
Report Highlights
Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Systemic Mastocytosis - Drugs In Development, 2022, provides comprehensive information on the therapeutics under development for Systemic Mastocytosis (Gastrointestinal), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.
The Systemic Mastocytosis (Gastrointestinal) pipeline guide also reviews of key players involved in therapeutic development for Systemic Mastocytosis and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Filing rejected/Withdrawn, Phase III, Phase II, Phase I and Preclinical stages are 1, 1, 4, 2 and 3 respectively.
Systemic Mastocytosis (Gastrointestinal) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.
Scope
- The pipeline guide provides a snapshot of the global therapeutic landscape of Systemic Mastocytosis (Gastrointestinal).
- The pipeline guide reviews pipeline therapeutics for Systemic Mastocytosis (Gastrointestinal) by companies and universities/research institutes based on information derived from company and industry-specific sources.
- The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
- The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
- The pipeline guide reviews key companies involved in Systemic Mastocytosis (Gastrointestinal) therapeutics and enlists all their major and minor projects.
- The pipeline guide evaluates Systemic Mastocytosis (Gastrointestinal) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
- The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
- The pipeline guide reviews latest news related to pipeline therapeutics for Systemic Mastocytosis (Gastrointestinal)
- Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
- Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
- Find and recognize significant and varied types of therapeutics under development for Systemic Mastocytosis (Gastrointestinal).
- Classify potential new clients or partners in the target demographic.
- Develop tactical initiatives by understanding the focus areas of leading companies.
- Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
- Formulate corrective measures for pipeline projects by understanding Systemic Mastocytosis (Gastrointestinal) pipeline depth and focus of Indication therapeutics.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
- Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.
Table of Contents
51 Pages
- Introduction
- Global Markets Direct Report Coverage
- Systemic Mastocytosis – Overview
- Systemic Mastocytosis – Therapeutics Development
- Pipeline Overview
- Pipeline by Companies
- Products under Development by Companies
- Systemic Mastocytosis – Therapeutics Assessment
- Assessment by Target
- Assessment by Mechanism of Action
- Assessment by Route of Administration
- Assessment by Molecule Type
- Systemic Mastocytosis – Companies Involved in Therapeutics Development
- A. Menarini Industrie Farmaceutiche Riunite Srl
- AB Science SA
- Allakos Inc
- Arog Pharmaceuticals Inc
- Blueprint Medicines Corp
- Cogent Biosciences Inc
- Hoth Therapeutics Inc
- Invea Therapeutics Inc
- MacroGenics Inc
- Seagen Inc
- Systemic Mastocytosis – Drug Profiles
- avapritinib – Drug Profile
- Bezuclastinib – Drug Profile
- BLU-263 – Drug Profile
- brentuximab vedotin – Drug Profile
- crenolanib besylate – Drug Profile
- HT-KIT – Drug Profile
- INVA-8001 – Drug Profile
- lirentelimab – Drug Profile
- masitinib – Drug Profile
- MGD-024 – Drug Profile
- tagraxofusp – Drug Profile
- Systemic Mastocytosis – Dormant Projects
- Systemic Mastocytosis – Discontinued Products
- Systemic Mastocytosis – Product Development Milestones
- Featured News & Press Releases
- Aug 17, 2022: Analysis Group announces study using real-world evidence to support Blueprint Medicines' AYVAKYT (avapritinib) label expansion for advanced systemic mastocytosis in Europe
- Jun 10, 2022: Cogent Biosciences to host investor webcast on June 10, 2022 at 8:00am ET
- Jun 10, 2022: Cogent Biosciences announces positive initial clinical data from ongoing phase 2 apex trial evaluating bezuclastinib in patients with Advanced Systemic Mastocytosis (AdvSM)
- Jun 09, 2022: Blueprint Medicines reports continued progress toward goal of transforming treatment of systemic mastocytosis
- May 12, 2022: Cogent Biosciences announces presentation at European Hematology Association (EHA) Annual Congress
- Apr 11, 2022: Cogent Biosciences presents nonclinical data at AACR Annual Meeting and provides updates on portfolio expansion at R&D Investor Event
- Apr 11, 2022: Hoth Therapeutics mRNA frame-shifting therapeutic, HT-KIT, proves effective against aggressive cancer cells
- Mar 29, 2022: Cogent Biosciences to host Virtual R&D Investor Event
- Mar 25, 2022: Blueprint medicines' AYVAKYT (avapritinib) receives European Commission approval for the treatment of adults with advanced systemic mastocytosis
- Mar 11, 2022: Hoth Therapeutics announces Orphan Drug Designation granted to cancer therapeutic HT-KIT to treat Mastocytosis
- Mar 08, 2022: Cogent Biosciences announces upcoming presentations at AACR annual meeting 2022
- Feb 17, 2022: EMA recommends extension of therapeutic indications for avapritinib
- Jan 28, 2022: Blueprint Medicines' AYVAKYT (avapritinib) receives positive CHMP opinion for the treatment of adults with advanced systemic mastocytosis
- Jan 19, 2022: AB Science has been granted authorization to initiate Phase II study in patients with severe mast cell activation syndrome by the French Health Authority (ANSM)
- Dec 21, 2021: Hoth Therapeutics announces submission of Orphan Drug Designation Request for HT-KIT to treat Mastocytosis
- Appendix
- Methodology
- Coverage
- Secondary Research
- Primary Research
- Expert Panel Validation
- Contact Us
- Disclaimer
- List of Tables
- Table 1: Number of Products under Development for Systemic Mastocytosis, 2022
- Table 2: Number of Products under Development by Companies, 2022
- Table 3: Products under Development by Companies, 2022
- Table 4: Number of Products by Stage and Target, 2022
- Table 5: Number of Products by Stage and Mechanism of Action, 2022
- Table 6: Number of Products by Stage and Route of Administration, 2022
- Table 7: Number of Products by Stage and Molecule Type, 2022
- Table 8: Systemic Mastocytosis – Pipeline by A. Menarini Industrie Farmaceutiche Riunite Srl, 2022
- Table 9: Systemic Mastocytosis – Pipeline by AB Science SA, 2022
- Table 10: Systemic Mastocytosis – Pipeline by Allakos Inc, 2022
- Table 11: Systemic Mastocytosis – Pipeline by Arog Pharmaceuticals Inc, 2022
- Table 12: Systemic Mastocytosis – Pipeline by Blueprint Medicines Corp, 2022
- Table 13: Systemic Mastocytosis – Pipeline by Cogent Biosciences Inc, 2022
- Table 14: Systemic Mastocytosis – Pipeline by Hoth Therapeutics Inc, 2022
- Table 15: Systemic Mastocytosis – Pipeline by Invea Therapeutics Inc, 2022
- Table 16: Systemic Mastocytosis – Pipeline by MacroGenics Inc, 2022
- Table 17: Systemic Mastocytosis – Pipeline by Seagen Inc, 2022
- Table 18: Systemic Mastocytosis – Dormant Projects, 2022
- Table 19: Systemic Mastocytosis – Discontinued Products, 2022
- List of Figures
- Figure 1: Number of Products under Development for Systemic Mastocytosis, 2022
- Figure 2: Number of Products under Development by Companies, 2022
- Figure 3: Number of Products by Top 10 Targets, 2022
- Figure 4: Number of Products by Stage and Top 10 Targets, 2022
- Figure 5: Number of Products by Top 10 Mechanism of Actions, 2022
- Figure 6: Number of Products by Stage and Top 10 Mechanism of Actions, 2022
- Figure 7: Number of Products by Routes of Administration, 2022
- Figure 8: Number of Products by Stage and Routes of Administration, 2022
- Figure 9: Number of Products by Molecule Types, 2022
- Figure 10: Number of Products by Stage and Top 10 Molecule Types, 2022
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