
Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) Drugs in Development by Therapy Areas and Indications, Stages, MoA, RoA, Molecule Type and Key Players, 2022 Update
Description
Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) Drugs in Development by Therapy Areas and Indications, Stages, MoA, RoA, Molecule Type and Key Players, 2022 Update
Summary
Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) pipeline Target constitutes close to 14 molecules. Out of which approximately 14 molecules are developed by Companies. The latest report Orexin Receptor Type 1 - Drugs In Development, 2022, outlays comprehensive information on the Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) - Orexin receptor type 1 (Ox1R or OX1) is a protein that is encoded by the HCRTR1 gene. The orexin 1 receptor (OX1) is a G-protein coupled receptor that is highly expressed in projections from the lateral hypothalamus and is involved in the regulation of feeding behavior. OX1 selectively binds the orexin-A neuropeptide. The molecules developed by companies in Pre-Registration, Phase III, Phase II, Phase I, Preclinical and Discovery stages are 2, 2, 2, 3, 4 and 1 respectively. Report covers products from therapy areas Central Nervous System, Respiratory and Gastrointestinal which include indications Insomnia, Binge Eating Disorder, Nicotine Addiction, Obstructive Sleep Apnea, Opium (Opioid) Addiction, Addiction, Alcohol Addiction, Chronic Obstructive Pulmonary Disease (COPD), Delirium, Dementia, Dementia Associated With Alzheimer's Disease, Major Depressive Disorder, Mild Cognitive Impairment, Narcolepsy, Panic Disorders, Parkinson's Disease, Reflux Esophagitis (Gastroesophageal Reflux Disease), Sleep Disorders, Smoking Cessation and Unspecified Psychiatric Disorders.
Furthermore, this report also reviews key players involved in Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.
Note:Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.
Scope
Summary
Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) pipeline Target constitutes close to 14 molecules. Out of which approximately 14 molecules are developed by Companies. The latest report Orexin Receptor Type 1 - Drugs In Development, 2022, outlays comprehensive information on the Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) - Orexin receptor type 1 (Ox1R or OX1) is a protein that is encoded by the HCRTR1 gene. The orexin 1 receptor (OX1) is a G-protein coupled receptor that is highly expressed in projections from the lateral hypothalamus and is involved in the regulation of feeding behavior. OX1 selectively binds the orexin-A neuropeptide. The molecules developed by companies in Pre-Registration, Phase III, Phase II, Phase I, Preclinical and Discovery stages are 2, 2, 2, 3, 4 and 1 respectively. Report covers products from therapy areas Central Nervous System, Respiratory and Gastrointestinal which include indications Insomnia, Binge Eating Disorder, Nicotine Addiction, Obstructive Sleep Apnea, Opium (Opioid) Addiction, Addiction, Alcohol Addiction, Chronic Obstructive Pulmonary Disease (COPD), Delirium, Dementia, Dementia Associated With Alzheimer's Disease, Major Depressive Disorder, Mild Cognitive Impairment, Narcolepsy, Panic Disorders, Parkinson's Disease, Reflux Esophagitis (Gastroesophageal Reflux Disease), Sleep Disorders, Smoking Cessation and Unspecified Psychiatric Disorders.
Furthermore, this report also reviews key players involved in Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.
Note:Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.
Scope
- The report provides a snapshot of the global therapeutic landscape for Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1)
- The report reviews Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) targeted therapeutics and enlists all their major and minor projects
- The report assesses Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) targeted therapeutics
- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
Table of Contents
77 Pages
- Introduction
- Global Markets Direct Report Coverage
- Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) – Overview
- Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) – Therapeutics Development
- Products under Development by Stage of Development
- Products under Development by Therapy Area
- Products under Development by Indication
- Products under Development by Companies
- Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) – Therapeutics Assessment
- Assessment by Mechanism of Action
- Assessment by Route of Administration
- Assessment by Molecule Type
- Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) – Companies Involved in Therapeutics Development
- Cerevance Inc
- Chronos Therapeutics Ltd
- Eisai Co Ltd
- Eolas Therapeutics Inc
- Idorsia Pharmaceutical Ltd
- Indivior Plc
- Inexia Ltd
- Johnson & Johnson
- Merck & Co Inc
- OXonium Therapeutics
- Taisho Pharmaceutical Holdings Co Ltd
- Yangtze River Pharmaceutical Group
- Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) – Drug Profiles
- CT-010018 – Drug Profile
- CTDP-002 – Drug Profile
- CVN-766 – Drug Profile
- daridorexant hydrochloride – Drug Profile
- Drugs to Antagonize Ox1 Receptor for Binge Eating Disorder – Drug Profile
- EORA-101 – Drug Profile
- INDV-2000 – Drug Profile
- JNJ-3215 – Drug Profile
- lemborexant – Drug Profile
- OPN-021 – Drug Profile
- Small Mollecules to Antagonize HCRTR1 for Addiction – Drug Profile
- suvorexant – Drug Profile
- TS-142 – Drug Profile
- YZJ-1139 – Drug Profile
- Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) – Dormant Products
- Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) – Discontinued Products
- Orexin Receptor Type 1 (Hypocretin Receptor Type 1 or HCRTR1) – Product Development Milestones
- Featured News & Press Releases
- Jul 19, 2022: Idorsia announces World Champion Skier, Philanthropist and Entrepreneur Lindsey Vonn as patient ambassador for QUVIVIQ (daridorexant), a Once Nightly Treatment for Insomnia
- Jun 03, 2022: Eisai to present latest data on lemborexant at the 36th Annual SLEEP 2022 Meeting
- May 13, 2022: Idorsia U.S. announces first wave of patients prescribed QUVIVIQ (daridorexant) through partnership with pharmacy services provider
- May 03, 2022: Europe’s first dual orexin receptor antagonist – QUVIVIQ (daridorexant) – granted approval to improve both nighttime symptoms and daytime functioning in adults with chronic insomnia disorder
- May 02, 2022: Idorsia’s new treatment QUVIVIQ (daridorexant) is now available in the US for adults living with insomnia
- Mar 10, 2022: New data for daridorexant in patients with insomnia disorder – including long-term safety and efficacy – to be presented at World Sleep 2022
- Feb 25, 2022: QUVIVIQ (daridorexant) recommended for approval in Europe as a new treatment for adults with insomnia disorder
- Jan 25, 2022: Cerevance doses first subjects in phase 1 clinical trial of CVN766
- Jan 20, 2022: The Lancet Neurology reports impact of daridorexant on both nighttime symptoms and daytime functioning in adults with insomnia
- Jan 10, 2022: Idorsia receives US FDA approval of QUVIVIQ (daridorexant) 25 and 50 mg for the treatment of adults with insomnia
- Jan 10, 2022: Idorsia presents at the 40th J.P. Morgan Healthcare Conference – Ready for first product launches – QUVIVIQ (daridorexant) approved by the US FDA
- Jun 30, 2021: Eisai launches in-house developed anti-insomnia drug Dayvigo (Lemborexant) in Hong Kong
- Jun 09, 2021: Idorsia to present new Phase 3 data on daridorexant in insomnia at SLEEP 2021
- Jun 09, 2021: Eisai to present latest data of Lemborexant at 35th Annual Sleep Meeting
- Mar 10, 2021: FDA accepts the new drug application for review of Idorsia’s daridorexant for the treatment of adult patients with insomnia
- Appendix
- Methodology
- Coverage
- Secondary Research
- Primary Research
- Expert Panel Validation
- Contact Us
- Disclaimer
- List of Tables
- Table 1: Number of Products under Development by Stage of Development, 2022
- Table 2: Number of Products under Development by Therapy Areas, 2022
- Table 3: Number of Products under Development by Indication, 2022
- Table 4: Number of Products under Development by Companies, 2022
- Table 5: Products under Development by Companies, 2022
- Table 6: Products under Development by Companies, 2022 (Contd..1)
- Table 7: Number of Products by Stage and Mechanism of Actions, 2022
- Table 8: Number of Products by Stage and Route of Administration, 2022
- Table 9: Number of Products by Stage and Molecule Type, 2022
- Table 10: Pipeline by Cerevance Inc, 2022
- Table 11: Pipeline by Chronos Therapeutics Ltd, 2022
- Table 12: Pipeline by Eisai Co Ltd, 2022
- Table 13: Pipeline by Eolas Therapeutics Inc, 2022
- Table 14: Pipeline by Idorsia Pharmaceutical Ltd, 2022
- Table 15: Pipeline by Indivior Plc, 2022
- Table 16: Pipeline by Inexia Ltd, 2022
- Table 17: Pipeline by Johnson & Johnson, 2022
- Table 18: Pipeline by Merck & Co Inc, 2022
- Table 19: Pipeline by OXonium Therapeutics, 2022
- Table 20: Pipeline by Taisho Pharmaceutical Holdings Co Ltd, 2022
- Table 21: Pipeline by Yangtze River Pharmaceutical Group, 2022
- Table 22: Dormant Products, 2022
- Table 23: Dormant Products, 2022 (Contd..1)
- Table 24: Discontinued Products, 2022
- List of Figures
- Figure 1: Number of Products under Development by Stage of Development, 2022
- Figure 2: Number of Products under Development by Therapy Areas, 2022
- Figure 3: Number of Products under Development by Top 10 Indications, 2022
- Figure 4: Number of Products by Stage and Mechanism of Actions, 2022
- Figure 5: Number of Products by Routes of Administration, 2022
- Figure 6: Number of Products by Stage and Routes of Administration, 2022
- Figure 7: Number of Products by Molecule Types, 2022
- Figure 8: Number of Products by Stage and Molecule Types, 2022
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