
Amyotrophic Lateral Sclerosis Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Description
Amyotrophic Lateral Sclerosis Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Summary
Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Amyotrophic Lateral Sclerosis - Drugs In Development, 2022, provides an overview of the Amyotrophic Lateral Sclerosis (Central Nervous System) pipeline landscape.
Amyotrophic lateral sclerosis (ALS) is the most common degenerative disease of the motor neuron system. The disorder is named for its underlying pathophysiology, with amyotrophy referring to the atrophy of muscle fibers, which are denervated as their corresponding anterior horn cells degenerate. Lateral sclerosis refers to the changes seen in the lateral columns of the spinal cord as upper motor neuron (UMN) axons in these areas degenerate and are replaced by fibrous astrocytes (gliosis). Symptoms include difficulty breathing, difficulty swallowing, head drop due to weakness of the neck muscles, muscle cramps, speech problems, such as a slow or abnormal speech pattern (slurring of words), voice changes, hoarseness, weight loss.
Report Highlights
Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Amyotrophic Lateral Sclerosis - Drugs In Development, 2022, provides comprehensive information on the therapeutics under development for Amyotrophic Lateral Sclerosis (Central Nervous System), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.
The Amyotrophic Lateral Sclerosis (Central Nervous System) pipeline guide also reviews of key players involved in therapeutic development for Amyotrophic Lateral Sclerosis and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Filing rejected/Withdrawn, Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical, Discovery and Unknown stages are 4, 1, 17, 46, 29, 5, 178, 80 and 4 respectively. Similarly, the Universities portfolio in Phase II, Preclinical and Discovery stages comprises 2, 38 and 14 molecules, respectively.
Amyotrophic Lateral Sclerosis (Central Nervous System) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.
Scope
Summary
Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Amyotrophic Lateral Sclerosis - Drugs In Development, 2022, provides an overview of the Amyotrophic Lateral Sclerosis (Central Nervous System) pipeline landscape.
Amyotrophic lateral sclerosis (ALS) is the most common degenerative disease of the motor neuron system. The disorder is named for its underlying pathophysiology, with amyotrophy referring to the atrophy of muscle fibers, which are denervated as their corresponding anterior horn cells degenerate. Lateral sclerosis refers to the changes seen in the lateral columns of the spinal cord as upper motor neuron (UMN) axons in these areas degenerate and are replaced by fibrous astrocytes (gliosis). Symptoms include difficulty breathing, difficulty swallowing, head drop due to weakness of the neck muscles, muscle cramps, speech problems, such as a slow or abnormal speech pattern (slurring of words), voice changes, hoarseness, weight loss.
Report Highlights
Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Amyotrophic Lateral Sclerosis - Drugs In Development, 2022, provides comprehensive information on the therapeutics under development for Amyotrophic Lateral Sclerosis (Central Nervous System), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.
The Amyotrophic Lateral Sclerosis (Central Nervous System) pipeline guide also reviews of key players involved in therapeutic development for Amyotrophic Lateral Sclerosis and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Filing rejected/Withdrawn, Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical, Discovery and Unknown stages are 4, 1, 17, 46, 29, 5, 178, 80 and 4 respectively. Similarly, the Universities portfolio in Phase II, Preclinical and Discovery stages comprises 2, 38 and 14 molecules, respectively.
Amyotrophic Lateral Sclerosis (Central Nervous System) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.
Scope
- The pipeline guide provides a snapshot of the global therapeutic landscape of Amyotrophic Lateral Sclerosis (Central Nervous System).
- The pipeline guide reviews pipeline therapeutics for Amyotrophic Lateral Sclerosis (Central Nervous System) by companies and universities/research institutes based on information derived from company and industry-specific sources.
- The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
- The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
- The pipeline guide reviews key companies involved in Amyotrophic Lateral Sclerosis (Central Nervous System) therapeutics and enlists all their major and minor projects.
- The pipeline guide evaluates Amyotrophic Lateral Sclerosis (Central Nervous System) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
- The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
- The pipeline guide reviews latest news related to pipeline therapeutics for Amyotrophic Lateral Sclerosis (Central Nervous System)
- Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
- Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
- Find and recognize significant and varied types of therapeutics under development for Amyotrophic Lateral Sclerosis (Central Nervous System).
- Classify potential new clients or partners in the target demographic.
- Develop tactical initiatives by understanding the focus areas of leading companies.
- Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
- Formulate corrective measures for pipeline projects by understanding Amyotrophic Lateral Sclerosis (Central Nervous System) pipeline depth and focus of Indication therapeutics.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
- Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.
Table of Contents
637 Pages
- Introduction
- Global Markets Direct Report Coverage
- Amyotrophic Lateral Sclerosis – Overview
- Amyotrophic Lateral Sclerosis – Therapeutics Development
- Pipeline Overview
- Pipeline by Companies
- Pipeline by Universities/Institutes
- Products under Development by Companies
- Products under Development by Universities/Institutes
- Amyotrophic Lateral Sclerosis – Therapeutics Assessment
- Assessment by Target
- Assessment by Mechanism of Action
- Assessment by Route of Administration
- Assessment by Molecule Type
- Amyotrophic Lateral Sclerosis – Companies Involved in Therapeutics Development
- 1st Bio Therapeutics Inc
- 2N Pharma ApS
- 4B Technologies (Suzhou) Co Ltd
- 4P-Pharma SAS
- AB Science SA
- Abbisko Cayman Limited
- Above and Beyond Concierge Therapeutics LLC
- AC Immune SA
- Aclipse One Inc
- Aclipse Therapeutics LLC
- Actimed Therapeutics Ltd
- AcuraStem Inc
- Adare Pharma Solutions
- Aeterna Zentaris Inc
- AgoneX Biopharmaceuticals Inc
- AI Therapeutics Inc
- AL-S Pharma AG
- Alector Inc
- Alexion Pharmaceuticals Inc
- Allife Medical Science and Technology Co Ltd
- Alnylam Pharmaceuticals Inc
- AlphaCognition Inc
- Alsonex Pty Ltd
- Amarna Therapeutics BV
- Amicogen Inc
- Amplo Biotechnology Inc
- Amylyx Pharmaceuticals Inc
- Anima Biotech Inc
- Ankar Pharma SL
- ANLBio Co Ltd
- Annexon Inc
- Apellis Pharmaceuticals Inc
- Apic Bio Inc
- Apogenix AG
- Applied Genetic Technologies Corp
- Aquilus Pharmaceuticals Inc
- Aquinnah Pharmaceuticals Inc
- AriBio
- ArmaGen Inc
- ArunA Bio Inc
- Asahi Kasei Pharma Corp
- Asdera LLC
- Asha Therapeutics LLC
- Ashvattha Therapeutics LLC
- Astellas Pharma Inc
- Astrogen Ltd
- Athira Pharma Inc
- Autotac Bio Inc
- Avanir Pharmaceuticals Inc
- AviadoBio Ltd
- Avrion Therapeutics AG
- BenevolentAI Ltd
- BioArctic AB
- Bioasis Technologies Inc
- Biogen Inc
- Biohaven Pharmaceutical Holding Company Ltd
- Bioleaders Corp
- Biolexis Therapeutics Inc
- Biorchestra Co Ltd
- Bisichem Co Ltd
- Bloom Science Inc
- BrainEver SAS
- BrainStorm Cell Therapeutics Inc
- Bruschettini Srl
- Calico Life Sciences LLC
- Capsida Biotherapeutics Inc
- CavoGene LifeSciences
- CellCure
- Cellenkos Inc
- Ceptur Therapeutics Inc
- Cerion LLC
- Chaperone Therapeutics Inc
- Chemigen LLC
- Chiesi Farmaceutici SpA
- CholesteniX Ltd
- Chronos Therapeutics Ltd
- Clene Inc
- Clevexel Pharma SA
- Clinigen Ltd
- Coave Therapeutics
- Codiak BioSciences Inc
- Cogentis Therapeutics Inc
- Collaborative Medicinal Development LLC
- Constant Therapeutics LLC
- Corcept Therapeutics Inc
- Corestem Inc
- Coya Therapeutics Inc
- Curatis AG
- CuroNZ Ltd
- Cytokinetics Inc
- Daiichi Sankyo Co Ltd
- Deargen Inc
- Denali Therapeutics Inc
- Dewpoint Therapeutics Inc
- Disarm Therapeutics Inc
- DR.Noah Biotech Inc
- Eikonizo Therapeutics Inc
- Eikonoklastes Therapeutics Inc
- Eisai Co Ltd
- Eledon Pharmaceuticals Inc
- Eli Lilly and Co
- Elixiron Immunotherapeutics Inc
- Elysium Health Inc
- EmendoBio Inc
- Emerald Health Sciences Inc
- ENCEFA
- Enveda Biosciences Inc
- Enzerna Biosciences LLC
- Eolo Pharma
- Everfront Biotech Inc
- Exicure Inc
- Expansion Therapeutics Inc
- Expesicor Inc
- Faze medicines
- Foshan Rexie Biotechnology Co Ltd
- Gene Therapy Research Institution Co Ltd
- Generoath Co Ltd
- Genervon Biopharmaceuticals LLC
- Genetic Intelligence Inc
- GeNeuro SA
- Genuv Inc
- Glialogix Inc
- GlyTag LLC
- GNT Pharma Co Ltd
- Grifols SA
- Grupo Ferrer Internacional SA
- Guangzhou Magpie Pharmaceutical Co Ltd
- Helixmith Co Ltd
- Hemostemix Inc
- Herantis Pharma Plc
- Hope Biosciences LLC
- Hopstem Biotechnology LLC
- Iltoo Pharma
- Immunity Pharma Ltd
- ImmunoBrain Checkpoint Inc
- ImmunoForge Co Ltd
- Implicit Bioscience Ltd
- ImStar Therapeutics Inc
- InFlectis BioScience SAS
- Inmune Bio Inc
- InnoMedica Holding AG
- InnoPharmaScreen Inc
- Io Therapeutics Inc
- Ionis Pharmaceuticals Inc
- Iron Horse Therapeutics Inc
- Jiangsu Ouwei Pharmaceutical Co Ltd
- Junaxo Inc
- Jupiter Neurosciences Inc
- K Pharma Inc
- K-Pax Pharmaceuticals Inc
- Kadimastem Ltd
- Keapstone Therapeutics Ltd
- KeifeRx LLC
- Klogene Therapeutics Inc
- Knopp Biosciences LLC
- Kringle Pharma Inc
- Kyorin Pharmaceutical Co Ltd
- Lascco SA
- Lauren Sciences LLC
- LifeSplice Pharma LLC
- Locanabio Inc
- Longboard Pharmaceuticals Inc
- Maas Biolab
- Maze Therapeutics Inc
- MD Healthcare Inc
- MedDay SA
- MeiraGTx Holdings Plc
- Merck & Co Inc
- MetrioPharm AG
- MetVital Inc
- MimeTech Srl
- Mitochon Pharmaceuticals Inc
- Mitochondria In Motion Inc
- Mitoconix Bio Ltd
- MitoDys Therapeutics Ltd
- Mitsubishi Tanabe Pharma Corp
- NeuExcell Therapeutics Inc
- Neugen Pharma Inc
- Neuracle Genetics Inc
- Neuracle Science Co Ltd
- Neurevo GmbH
- Neurimmune Holding AG
- Neurodegeneration Therapeutics Inc
- NeuroGenesis Ltd
- Neuromagen Pharma Ltd
- Neuropath Therapeutics Ltd
- Neuroplast BV
- Neuropore Therapies Inc
- NeuroSense Therapeutics Ltd
- Neurotune AG
- Neuvivo Inc
- Nevrox Ltd
- New Biotic Inc
- Newron Pharmaceuticals SpA
- Nine Square Therapeutics Inc
- Nobelpharma Co Ltd
- Novartis AG
- Novartis Gene Therapies
- NovelMed Therapeutics Inc
- NuNerve Pty Ltd
- NysnoBio LLC
- Oncocross Co Ltd
- OptiKira LLC
- Orchard Therapeutics Plc
- Origami Therapeutics Inc
- Orpheris Inc
- Palisade Bio, Inc
- Parnia Stem Cell Knowledge-Based Co
- Pasithea Therapeutics Corp
- Passage Bio Inc
- Pfizer Inc
- PharmaTher Holdings Ltd
- PharmAust Ltd
- PharmEnable Ltd
- Pharnext SA
- Plex Pharmaceuticals Inc
- PRG S&Tech Inc
- Priavoid GmbH
- Prilenia Therapeutics Development Ltd
- Projenx Inc
- ProMIS Neurosciences Inc
- Prosetta Biosciences Inc
- Prothena Corp Plc
- Prous Institute for Biomedical Research SA
- PTC Therapeutics Inc
- PurMinds NeuroPharma Inc
- Q Therapeutics Inc
- Q-State Biosciences Inc
- QurAlis Corporation
- Ra Pharmaceuticals Inc
- Rapa Therapeutics LLC
- RASRx LLC
- Reata Pharmaceuticals Inc
- ReceptoPharm Inc
- Regulus Therapeutics Inc
- reMYND NV
- ReoStem LLC
- ResQ Biotech
- Retrotope Inc
- Revalesio Corp
- Sangamo Therapeutics Inc
- SciNeuro Pharmaceuticals
- Seelos Therapeutics, Inc.
- Shanghai Pharmaceuticals Holding Co Ltd
- Shanghai Zhimeng Biopharma Inc
- Shinkei Therapeutics LLC
- Sio Gene Therapies Inc
- SOLA Biosciences LLC
- Spedding Research Solutions SAS
- Spinogenix Inc
- Stealth BioTherapeutics Corp
- Suzhou Auzone Biological Technology Co Ltd
- Symbinas Pharmaceuticals Inc
- Takara Bio Inc
- Talon Pharmaceutical Services Inc
- Tasly Biopharmaceuticals Co Ltd
- Tempero Bio
- Thera Neuropharma Inc
- Theragen Etex Co Ltd
- Theratome Bio Inc
- TikoMed AB
- Tranquis Therapeutics Inc
- Transposon Therapeutics Inc
- Treeway BV
- Treventis Corp
- Triplet Therapeutics Inc
- Ultragenyx Pharmaceutical Inc
- UniQure NV
- Unity Biotechnology Inc
- Vanqua Bio Inc
- Vaxxinity Inc
- VectorY Therapeutics Inc
- Velvio GmbH
- Verge Genomics
- Viridian Therapeutics Inc
- Voronoi Group
- Voyager Therapeutics Inc
- Wave Life Sciences Ltd
- Wren Therapeutics Ltd
- Xalud Therapeutics Inc
- XellSmart Biomedical (Shanghai) Co Ltd
- Xonovo Inc
- Yantai YenePharma Co Ltd
- Yumanity Therapeutics Inc
- Zhittya Genesis Medicine Inc
- ZZ Biotech LLC
- Amyotrophic Lateral Sclerosis – Drug Profiles
- (acamprosate calcium + baclofen) – Drug Profile
- (borneol + edaravone) – Drug Profile
- (celecoxib + ciprofloxacin) – Drug Profile
- (dextromethorphan + quinidine sulfate) – Drug Profile
- (sodium phenylbutyrate + taurursodiol) – Drug Profile
- 123C-4 – Drug Profile
- 1ST-102 – Drug Profile
- 1ST-103 – Drug Profile
- 1ST-104 – Drug Profile
- 3K3A-APC – Drug Profile
- 4P-019 – Drug Profile
- AAD-2004 – Drug Profile
- AAV-UPF1 – Drug Profile
- AB-200 – Drug Profile
- ABBVCLS-7262 – Drug Profile
- ABSK-021 – Drug Profile
- ACI-5891 – Drug Profile
- ACM-002 – Drug Profile
- AGS-499 – Drug Profile
- AGT-110 – Drug Profile
- AGTC-801 – Drug Profile
- albumin (human) – Drug Profile
- aldesleukin – Drug Profile
- ALN-SOD – Drug Profile
- ALPHA-0602 – Drug Profile
- ALPHA-0603 – Drug Profile
- ALS – Drug Profile
- ALS PIKFYVE – Drug Profile
- ALS Target (Small Molecule/ASO) – Drug Profile
- ALS Vaccine – Drug Profile
- ALS-205 – Drug Profile
- ALS/FTD – Drug Profile
- AMA-007 – Drug Profile
- ambroxol hydrochloride – Drug Profile
- AMP-101 – Drug Profile
- AMT-161 – Drug Profile
- Amyotrophic Lateral Sclerosis (ALS) – Drug Profile
- AMYOTROPHIC LATERAL SCLEROSIS (C9ORF72) – Drug Profile
- Amyotrophic lateral sclerosis 2 – Drug Profile
- Anhydrous enol oxaloacetate – Drug Profile
- ANL-303 – Drug Profile
- Antibodies to Inhibit TARDBP for Amyotrophic Lateral Sclerosis – Drug Profile
- Antisense Oligonucleotide for Neurodegenerative Diseases – Drug Profile
- Antisense Oligonucleotide to Inhibit Tau Protein for Neurodegenerative Disorders – Drug Profile
- Antisense Oligonucleotides for Amyotrophic Lateral Sclerosis – Drug Profile
- ANX-005 – Drug Profile
- AP-101 – Drug Profile
- APB-102 – Drug Profile
- APB-104 – Drug Profile
- APB-105 – Drug Profile
- apilimod mesylate – Drug Profile
- apomorphine hydrochloride – Drug Profile
- AQU-118 – Drug Profile
- AR-1001 – Drug Profile
- AS-1 – Drug Profile
- AS-201 – Drug Profile
- AS-202 – Drug Profile
- AS-203 – Drug Profile
- ASD-005 – Drug Profile
- ASHA-624 – Drug Profile
- ASR-149 – Drug Profile
- AST-011 – Drug Profile
- AstroRx – Drug Profile
- asunercept – Drug Profile
- Ataxin2 – Drug Profile
- ATC-104 – Drug Profile
- AVR-001 – Drug Profile
- AVXS-301 – Drug Profile
- B-2069 – Drug Profile
- baricitinib – Drug Profile
- BEN-9160 – Drug Profile
- BEN-XX1 – Drug Profile
- BHV-TBD 1 – Drug Profile
- BIIB-100 – Drug Profile
- biotin – Drug Profile
- BL-001 – Drug Profile
- BLSM-22 – Drug Profile
- BLX-0200 – Drug Profile
- BMD-001 – Drug Profile
- BMD-002 – Drug Profile
- BNN-27 – Drug Profile
- bosutinib – Drug Profile
- BREN-01 – Drug Profile
- BREN-02 – Drug Profile
- BSC-3301 – Drug Profile
- CALS-01 – Drug Profile
- CB-003 – Drug Profile
- CC-100 – Drug Profile
- Cell Therapy for Autoimmune Disorders, Cardiovascular Disorders, CNS Disorders, Infectious Disease, Musculoskeletal Disorders and Oncology – Drug Profile
- Cell Therapy for Central Nervous System and Neurodegenerative Diseases – Drug Profile
- censavudine – Drug Profile
- Cerium dioxide – Drug Profile
- CH1 – Drug Profile
- CHEC-9 – Drug Profile
- CHX-100xD – Drug Profile
- CK-0802 – Drug Profile
- CK-0803 – Drug Profile
- CL-2020 – Drug Profile
- CNMAU-8 – Drug Profile
- COYA-101 – Drug Profile
- CT-526 – Drug Profile
- CTx-FUS – Drug Profile
- Cu(II)ATSM – Drug Profile
- CVXL-0301 – Drug Profile
- cyclosporine – Drug Profile
- DAR-004 – Drug Profile
- dazucorilant – Drug Profile
- debamestrocel – Drug Profile
- deferiprone – Drug Profile
- deulinoleate ethyl – Drug Profile
- DGALST-1 – Drug Profile
- DNL-343 – Drug Profile
- DNL-788 – Drug Profile
- donaperminogene seltoplasmid – Drug Profile
- Drug Candidates – Drug Profile
- Drug for Alzheimer's Disease and Amyotrophic Lateral Sclerosis (ALS) – Drug Profile
- Drug for Amyotrophic Lateral Sclerosis – Drug Profile
- Drug for Amyotrophic Lateral Sclerosis (ALS) – Drug Profile
- Drug for Neurological Disorders – Drug Profile
- Drugs for Amyotrophic Lateral Sclerosis – Drug Profile
- Early compounds – Drug Profile
- edaravone – Drug Profile
- EH-301 – Drug Profile
- EHP-102 – Drug Profile
- EI-1071 – Drug Profile
- EKZ-001 – Drug Profile
- EMD-402 – Drug Profile
- ENZ-002 – Drug Profile
- EOLO-10 – Drug Profile
- EPI-589 – Drug Profile
- ET-101 – Drug Profile
- Exosome Vaccine – Drug Profile
- EXP-200 – Drug Profile
- fasudil – Drug Profile
- FB-1002 – Drug Profile
- FB-1006 – Drug Profile
- FB-418 – Drug Profile
- FGF-1 – Drug Profile
- Fusion Protein to Antagonize EPHA4 for CNS Disorders, Cardiovascular Diseases and Sepsis – Drug Profile
- GB-1 – Drug Profile
- Gene Therapies for Amyotrophic Lateral Sclerosis – Drug Profile
- Gene Therapies to Inhibit C9ORF72 for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia – Drug Profile
- Gene Therapy 1 for Amyotrophic Lateral Sclerosis (AML) and Frontotemporal Dementia (FTD) – Drug Profile
- Gene Therapy for Amyotrophic Lateral Sclerosis – Drug Profile
- Gene Therapy for Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) – Drug Profile
- Gene Therapy for Amyotrophic Lateral Sclerosis and Dementia – Drug Profile
- Gene Therapy for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia – Drug Profile
- Gene Therapy for Central Nervous System Disorders – Drug Profile
- Gene Therapy for Diabetic Retinopathy, Neurodegenerative Diseases and Wet Macular Degeneration – Drug Profile
- Gene Therapy for Genetic Disorders, Neurology, Musculoskeletal and Ophthalmology – Drug Profile
- Gene Therapy to Activate GDNF for Amyotrophic Lateral Sclerosis and Retinitis Pigmentosa – Drug Profile
- Gene Therapy to Activate Interleukin-10 for ALS – Drug Profile
- Gene Therapy to Activate SYT13 for Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy – Drug Profile
- Gene Therapy To Target ATXN2 for Amyotrophic Lateral Sclerosis – Drug Profile
- Genetic Form of ALS – Drug Profile
- GlyB-4 – Drug Profile
- Glycolic acid + D-lactic acid – Drug Profile
- GM-6 – Drug Profile
- GNK-301 – Drug Profile
- GO-102 – Drug Profile
- GT-0001X – Drug Profile
- histamine dihydrochloride – Drug Profile
- HK-001 – Drug Profile
- hNPC-02 – Drug Profile
- HTL-0014242 – Drug Profile
- HYNR-CS-Allo – Drug Profile
- ibudilast – Drug Profile
- IC-14 – Drug Profile
- icerguastat – Drug Profile
- IMS-088 – Drug Profile
- ION-541 – Drug Profile
- IPL-344 – Drug Profile
- IPS-07004 – Drug Profile
- IRX-4204 – Drug Profile
- JAK-4D – Drug Profile
- JMF-3464 – Drug Profile
- JNS-109 – Drug Profile
- JRP-655 – Drug Profile
- JRP-900 – Drug Profile
- ketamine – Drug Profile
- KFRX-03 – Drug Profile
- KPAX-002 – Drug Profile
- latozinemab – Drug Profile
- LAUR-301 – Drug Profile
- Library of Oligonucleotides – Drug Profile
- LP-143 – Drug Profile
- LSPGR-1 – Drug Profile
- LSPGR-3 – Drug Profile
- M-102 – Drug Profile
- macimorelin acetate – Drug Profile
- masitinib – Drug Profile
- MDH-001 – Drug Profile
- MDH-204 – Drug Profile
- MDN-0005 – Drug Profile
- mecobalamin – Drug Profile
- MiM-111 – Drug Profile
- Mitometin – Drug Profile
- monepantel – Drug Profile
- MP-101 – Drug Profile
- MP-1032 – Drug Profile
- MP-201 – Drug Profile
- MR-401 – Drug Profile
- MRG-107 – Drug Profile
- MT-2 – Drug Profile
- MTC-1203 – Drug Profile
- NB-001 – Drug Profile
- NCB-8 – Drug Profile
- NCP-01 – Drug Profile
- ND-3014 – Drug Profile
- NDBT-3814 – Drug Profile
- NDC-011 – Drug Profile
- Neuronata-R – Drug Profile
- NG-1 – Drug Profile
- NG-2 – Drug Profile
- NG-201ALS – Drug Profile
- NI-205 – Drug Profile
- NI-308 – Drug Profile
- NP-001 – Drug Profile
- NPT-1220312 – Drug Profile
- NPT-1220478 – Drug Profile
- NPT-52034 – Drug Profile
- NRP-2945 – Drug Profile
- NSI-566 – Drug Profile
- NT-1654 – Drug Profile
- NU-9 – Drug Profile
- NVP-13 – Drug Profile
- NXL-003 – Drug Profile
- OC-514 – Drug Profile
- Oligonucleotides for Amyotrophic Lateral Sclerosis and Spinocerebellar Ataxia – Drug Profile
- omaveloxolone – Drug Profile
- OP-101 – Drug Profile
- OP-329 – Drug Profile
- OP-330 – Drug Profile
- OP-401 – Drug Profile
- oremepermin alfa – Drug Profile
- OTL-205 – Drug Profile
- P7-C3A20 – Drug Profile
- PAT-103 – Drug Profile
- PBAL-05 – Drug Profile
- pegcetacoplan – Drug Profile
- pegipanermin – Drug Profile
- Peptide to Activate GLP1R for CNS Disorders, and Head Trauma – Drug Profile
- Peptide to Agonize NTRK2 for Amyotrophic Lateral Sclerosis, Depression and Parkinson's Disease – Drug Profile
- Peptides to Activate GLP-1 Receptor for CNS Disorders, Cardiac Diseases and Head Trauma – Drug Profile
- perampanel – Drug Profile
- PF-1802 – Drug Profile
- PRG-CNS-1 – Drug Profile
- PRI-003 – Drug Profile
- PRI-500 – Drug Profile
- pridopidine hydrochloride – Drug Profile
- prosetin – Drug Profile
- Protein for Amyotrophic Lateral Sclerosis – Drug Profile
- Proteins for Immunology and Metabolic Disorders – Drug Profile
- PTC-857 – Drug Profile
- Q-Cells – Drug Profile
- QRA-244 – Drug Profile
- QRL-201 – Drug Profile
- RACK1 – Drug Profile
- RAPA-501 – Drug Profile
- RaphaLX – Drug Profile
- RASRx-1902 – Drug Profile
- RDC-5 – Drug Profile
- Recombinant Glutamate Oxaloacetate Transaminase for Brain Stroke, Amyotrophic Lateral Sclerosis, Spinal Cord Injury and Glioblastoma – Drug Profile
- Recombinant Peptide for Parkinson's Disease and Amyotrophic Lateral Sclerosis – Drug Profile
- Recombinant Peptides to Inhibit Superoxide Dismutase (SOD1) for Amyotrophic Lateral Sclerosis – Drug Profile
- Recombinant Peptides to Inhibit TDP-43 for Amyotrophic Lateral Sclerosis – Drug Profile
- Recombinant Protein for Amyotrophic Lateral Sclerosis – Drug Profile
- Recombinant Protein to Activate TFAM for Ageing and Neurodegenerative Diseases – Drug Profile
- reldesemtiv – Drug Profile
- riluzole – Drug Profile
- RNAi Gene Therapy to Inhibit SOD1 for Amyotrophic Lateral Sclerosis – Drug Profile
- RNS-60 – Drug Profile
- rolipram – Drug Profile
- ropinirole hydrochloride ER – Drug Profile
- RPI-78M – Drug Profile
- RY-103 – Drug Profile
- safinamide mesylate – Drug Profile
- SBT-272 – Drug Profile
- Scleron – Drug Profile
- scopolamine – Drug Profile
- Senolytics – Drug Profile
- sirolimus – Drug Profile
- Small Molecule 2 for Amyotrophic Lateral Sclerosis – Drug Profile
- Small Molecule for Amyotrophic Lateral Sclerosis – Drug Profile
- Small Molecule for Neurodegenerative Diseases – Drug Profile
- Small Molecule to Activate KvLQT2 , KvLQT3 and KvLQT4 for Amyotrophic Lateral Sclerosis – Drug Profile
- Small Molecule to Block Cav1.3 and Free Radicals for Central Nervous System, Metabolic Disorders and Cardiovascular Diseases – Drug Profile
- Small Molecule to Inhibit Glutamine Synthetase for Amyotrophic Lateral Sclerosis – Drug Profile
- Small Molecule to Inhibit HSP90 and FK506 for Amyotrophic Lateral Sclerosis – Drug Profile
- Small Molecule to Inhibit Protein Disulfide Isomerase for Amyotrophic Lateral Sclerosis and Huntington Disease – Drug Profile
- Small Molecule to Inhibit Rho kinase for Amyotrophic Lateral Sclerosis – Drug Profile
- Small Molecules for Alzheimer's Disease and Multiple Sclerosis – Drug Profile
- Small Molecules for Amyotrophic Lateral Sclerosis – Drug Profile
- Small Molecules for Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Lobar Dementia (FTLD) – Drug Profile
- Small Molecules for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia – Drug Profile
- Small Molecules for Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Dementia (FTLD) – Drug Profile
- Small Molecules for Amyotrophic Lateral Sclerosis and Parkinson's Disease – Drug Profile
- Small Molecules for Central Nervous System Disorders – Drug Profile
- Small Molecules for Mitochondrial and Central Nervous System Disorders – Drug Profile
- Small Molecules for Neurodegenerative Disease – Drug Profile
- Small Molecules for Neurodegenerative Diseases – Drug Profile
- Small Molecules for Neurology – Drug Profile
- Small Molecules to Activate HSF-1 for Amyotrophic Lateral Sclerosis – Drug Profile
- Small Molecules to Inhibit C9ORF72 for Amyotrophic Lateral Sclerosis – Drug Profile
- Small Molecules to Inhibit Dbr1 for Amyotrophic Lateral Sclerosis – Drug Profile
- Small Molecules to Inhibit GSK3B for Amyotropic Lateral Sclerosis – Drug Profile
- Small Molecules to Inhibit Ire1-Alpha for Amyotrophic Lateral Sclerosis, Idiopathic Pulmonary Fibrosis, Retinitis Pigmentosa and Type 2 Diabetes – Drug Profile
- Small Molecules to Inhibit KEAP1 for Amyotrophic Lateral Sclerosis and Parkinson’s Disease – Drug Profile
- Small Molecules to Inhibit SARM1 for Neurology and Glaucoma – Drug Profile
- Small Molecules to Inhibit SOD1 for Amyotrophic Lateral Sclerosis – Drug Profile
- Small Molecules to Inhibit TANA for Amyotrophic Lateral Sclerosis, Alzheimer's Disease and Dementia – Drug Profile
- Small Molecules to Inhibit TDP43 for Amyotrophic Lateral Sclerosis – Drug Profile
- Small-Molecule Therapeutics – Drug Profile
- SMB-001 – Drug Profile
- smilagenin – Drug Profile
- SNP-203 – Drug Profile
- SNP-206 – Drug Profile
- SNP-210 – Drug Profile
- SOD1 – Drug Profile
- SOL-257 – Drug Profile
- SOL-258 – Drug Profile
- sotuletinib – Drug Profile
- SRD-4512 – Drug Profile
- Stem Cell Therapy for Amyotrophic Lateral Sclerosis – Drug Profile
- Stem Cell Therapy for Amyotrophic Lateral Sclerosis and Duchenne Muscular Dystrophy – Drug Profile
- Stem Cell Therapy for Central Nervous System Disorders – Drug Profile
- Stem Cell Therapy for Parkinson's Disease – Drug Profile
- sulfasalazine – Drug Profile
- SYN-1 – Drug Profile
- SYN-2 – Drug Profile
- SYNCAV-1 – Drug Profile
- Synthetic Peptide Agonize TrkA and TrkB Alzheimer's Disease and Amyotrophic Lateral Sclerosis – Drug Profile
- Synthetic Peptide for Neurological and Psychiatric Diseases – Drug Profile
- Synthetic Peptides for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia – Drug Profile
- Synthetic Peptides to Activate PACAP Receptor and Antagonize VPAC1, VPAC2 for Neurological Disorders – Drug Profile
- tauroursodeoxycholic acid – Drug Profile
- TDI-104 – Drug Profile
- TDI-106 – Drug Profile
- TDI-142 – Drug Profile
- TDI-158 – Drug Profile
- TDI-163 – Drug Profile
- TDI-168 – Drug Profile
- TDI-186 – Drug Profile
- TDI-197 – Drug Profile
- TDI-201 – Drug Profile
- TDI-202 – Drug Profile
- TDI-206 – Drug Profile
- TDI-207 – Drug Profile
- TDI-208 – Drug Profile
- TDI-209 – Drug Profile
- TDI-210 – Drug Profile
- TDI-211 – Drug Profile
- TDI-28 – Drug Profile
- TDI-53 – Drug Profile
- TDP-43 – Drug Profile
- tegoprubart – Drug Profile
- Thera-101 – Drug Profile
- THN-1 – Drug Profile
- tiomolibdate choline – Drug Profile
- TLSG-1 – Drug Profile
- TM-700 – Drug Profile
- tofersen sodium – Drug Profile
- TQS-168 – Drug Profile
- trametinib – Drug Profile
- trehalose – Drug Profile
- triheptanoin – Drug Profile
- TTX-3360 – Drug Profile
- TW-002 – Drug Profile
- TXA-127 – Drug Profile
- ulefnersen sodium – Drug Profile
- Undisclosed Target – Drug Profile
- Vaccine for Neurodegenerative Diseases – Drug Profile
- verdiperstat – Drug Profile
- VM-301 – Drug Profile
- VRN-042 – Drug Profile
- VTx-001 – Drug Profile
- VTx-002 – Drug Profile
- VYSOD-101 – Drug Profile
- VYSOD-102 – Drug Profile
- WN-1316 – Drug Profile
- WVE-004 – Drug Profile
- xB3-Progranulin – Drug Profile
- XN-001 – Drug Profile
- XS-002 – Drug Profile
- XT-101 – Drug Profile
- XT-150 – Drug Profile
- YSB-201 – Drug Profile
- zilucoplan – Drug Profile
- Amyotrophic Lateral Sclerosis – Dormant Projects
- Amyotrophic Lateral Sclerosis – Discontinued Products
- Amyotrophic Lateral Sclerosis – Product Development Milestones
- Featured News & Press Releases
- Oct 11, 2022: NeuroSense Therapeutics to present at upcoming U.S. and European ALS Conferences
- Sep 24, 2022: Clene Nanomedicine presents updated long-term survival data from RESCUE-ALS participants at 2022 AANEM Scientific Conference
- Sep 22, 2022: Biogen’s tofersen lowers molecular signs of ALS in Phase III trial
- Sep 21, 2022: Cellenkos receives FDA clearance of Investigational New Drug (IND) application for CK0803 for the treatment of Amyotrophic Lateral Sclerosis (ALS)
- Sep 20, 2022: NeuroSense announces positive PrimeC toxicology data supportive of current phase IIb PARADIGM ALS Clinical Trial
- Sep 19, 2022: NeuroSense announces peer-reviewed publication of PrimeC phase IIa ALS study in amyotrophic lateral sclerosis and frontotemporal degeneration
- Sep 15, 2022: BioJiva reports results of pilot phase 2 clinical trial of RT001 in patients with amyotrophic lateral sclerosis (ALS)
- Sep 14, 2022: Amylyx Pharmaceuticals announces donated CENTAUR clinical trial data now available to help advance science in ALS for future treatments and discoveries
- Sep 12, 2022: Amylyx Pharmaceuticals announces publication of preclinical data showing potential synergistic effect of AMX0035 compared to individual compounds
- Sep 07, 2022: Helixmith reports Phase IIA data for Engensis to treat ALS
- Sep 07, 2022: Amylyx Pharmaceuticals announces FDA advisory committee supports approval of AMX0035 for the treatment of ALS
- Sep 07, 2022: Amylyx Pharmaceuticals announces FDA plan to reconvene Advisory Committee to review AMX0035 NDA for the treatment of ALS
- Sep 02, 2022: Tranquis Therapeutics to present preclinical data on TQS-168 at ARDD 2022
- Sep 02, 2022: Amylyx Pharmaceuticals announces posting of briefing documents for second FDA Advisory Committee Meeting on AMX0035
- Sep 01, 2022: Coya Therapeutics announces peer-reviewed publication of phase 2a clinical trial data for COYA 101 in Amyotrophic Lateral Sclerosis (ALS)
- Appendix
- Methodology
- Coverage
- Secondary Research
- Primary Research
- Expert Panel Validation
- Contact Us
- Disclaimer
- List of Tables
- Table 1: Number of Products under Development for Amyotrophic Lateral Sclerosis, 2022
- Table 2: Number of Products under Development by Companies, 2022
- Table 3: Number of Products under Development by Companies, 2022 (Contd..1)
- Table 4: Number of Products under Development by Companies, 2022 (Contd..2)
- Table 5: Number of Products under Development by Companies, 2022 (Contd..3)
- Table 6: Number of Products under Development by Companies, 2022 (Contd..4)
- Table 7: Number of Products under Development by Companies, 2022 (Contd..5)
- Table 8: Number of Products under Development by Companies, 2022 (Contd..6)
- Table 9: Number of Products under Development by Companies, 2022 (Contd..7)
- Table 10: Number of Products under Development by Companies, 2022 (Contd..8)
- Table 11: Number of Products under Development by Companies, 2022 (Contd..9)
- Table 12: Number of Products under Development by Companies, 2022 (Contd..10)
- Table 13: Number of Products under Development by Companies, 2022 (Contd..11)
- Table 14: Number of Products under Development by Companies, 2022 (Contd..12)
- Table 15: Number of Products under Development by Companies, 2022 (Contd..13)
- Table 16: Number of Products under Development by Companies, 2022 (Contd..14)
- Table 17: Number of Products under Development by Universities/Institutes, 2022
- Table 18: Number of Products under Development by Universities/Institutes, 2022 (Contd..1)
- Table 19: Products under Development by Companies, 2022
- Table 20: Products under Development by Companies, 2022 (Contd..1)
- Table 21: Products under Development by Companies, 2022 (Contd..2)
- Table 22: Products under Development by Companies, 2022 (Contd..3)
- Table 23: Products under Development by Companies, 2022 (Contd..4)
- Table 24: Products under Development by Companies, 2022 (Contd..5)
- Table 25: Products under Development by Companies, 2022 (Contd..6)
- Table 26: Products under Development by Companies, 2022 (Contd..7)
- Table 27: Products under Development by Companies, 2022 (Contd..8)
- Table 28: Products under Development by Companies, 2022 (Contd..9)
- Table 29: Products under Development by Companies, 2022 (Contd..10)
- Table 30: Products under Development by Companies, 2022 (Contd..11)
- Table 31: Products under Development by Companies, 2022 (Contd..12)
- Table 32: Products under Development by Companies, 2022 (Contd..13)
- Table 33: Products under Development by Companies, 2022 (Contd..14)
- Table 34: Products under Development by Companies, 2022 (Contd..15)
- Table 35: Products under Development by Companies, 2022 (Contd..16)
- Table 36: Products under Development by Companies, 2022 (Contd..17)
- Table 37: Products under Development by Companies, 2022 (Contd..18)
- Table 38: Products under Development by Companies, 2022 (Contd..19)
- Table 39: Products under Development by Companies, 2022 (Contd..20)
- Table 40: Products under Development by Companies, 2022 (Contd..21)
- Table 41: Products under Development by Universities/Institutes, 2022
- Table 42: Products under Development by Universities/Institutes, 2022 (Contd..1)
- Table 43: Products under Development by Universities/Institutes, 2022 (Contd..2)
- Table 44: Number of Products by Stage and Target, 2022
- Table 45: Number o
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