
Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Description
Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Summary
Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) pipeline Target constitutes close to 6 molecules. The latest report Alpha 2C Adrenergic Receptor - Drugs In Development, 2022, outlays comprehensive information on the Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) - Alpha-2C adrenergic receptor or ADRA2C is an alpha-2 adrenergic receptor. It mediates the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. This receptor plays a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The molecules developed by companies in Phase III, Phase II, Phase I and Preclinical stages are 2, 1, 2 and 1 respectively. Report covers products from therapy areas Central Nervous System and Undisclosed which include indications Dementia Associated With Alzheimer's Disease, Major Depressive Disorder, Schizophrenia, Alzheimer's Disease, Bipolar Disorder (Manic Depression), Cognitive Disorders, Depression, Generalized Anxiety Disorder (GAD), Pervasive Developmental Disorder (PDD), Post-Traumatic Stress Disorder (PTSD) and Unspecified.
Furthermore, this report also reviews key players involved in Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.
Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.
Scope
Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Summary
Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) pipeline Target constitutes close to 6 molecules. The latest report Alpha 2C Adrenergic Receptor - Drugs In Development, 2022, outlays comprehensive information on the Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) - Alpha-2C adrenergic receptor or ADRA2C is an alpha-2 adrenergic receptor. It mediates the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. This receptor plays a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The molecules developed by companies in Phase III, Phase II, Phase I and Preclinical stages are 2, 1, 2 and 1 respectively. Report covers products from therapy areas Central Nervous System and Undisclosed which include indications Dementia Associated With Alzheimer's Disease, Major Depressive Disorder, Schizophrenia, Alzheimer's Disease, Bipolar Disorder (Manic Depression), Cognitive Disorders, Depression, Generalized Anxiety Disorder (GAD), Pervasive Developmental Disorder (PDD), Post-Traumatic Stress Disorder (PTSD) and Unspecified.
Furthermore, this report also reviews key players involved in Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.
Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.
Scope
- The report provides a snapshot of the global therapeutic landscape for Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C)
- The report reviews Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) targeted therapeutics and enlists all their major and minor projects
- The report assesses Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) targeted therapeutics
- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C)Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
Table of Contents
51 Pages
- Introduction
- Global Markets Direct Report Coverage
- Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) – Overview
- Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) – Therapeutics Development
- Products under Development by Stage of Development
- Products under Development by Therapy Area
- Products under Development by Indication
- Products under Development by Companies
- Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) – Therapeutics Assessment
- Assessment by Mechanism of Action
- Assessment by Route of Administration
- Assessment by Molecule Type
- Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) – Companies Involved in Therapeutics Development
- Avineuro Pharmaceuticals Inc
- Bayer AG
- Denovo Biopharma LLC
- Midatech Pharma Plc
- Otsuka Pharmaceutical Co Ltd
- SK Life Science Inc
- Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) – Drug Profiles
- apomorphine hydrochloride – Drug Profile
- AVN-101 – Drug Profile
- BAY-2925976 – Drug Profile
- brexpiprazole – Drug Profile
- brexpiprazole SR – Drug Profile
- DB-105 – Drug Profile
- SKL-PSY – Drug Profile
- Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) – Dormant Products
- Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) – Discontinued Products
- Alpha 2C Adrenergic Receptor (Alpha 2 Adrenergic Receptor Subtype C4 or Alpha 2C Adrenoreceptor or ADRA2C) – Product Development Milestones
- Featured News & Press Releases
- Dec 01, 2022: Otsuka Pharmaceutical & Lundbeck present positive data from multiple phase 3 studies showing Brexpiprazole significantly improved symptoms of agitation in patients with Alzheimer’s dementia at the 2022 Clinical Trials for Alzheimer’s Disease Congress
- Sep 12, 2022: Otsuka Pharmaceutical announces positive results of phase III trial in Japan for brexpiprazole in the treatment of major depressive disorder
- Aug 04, 2022: Otsuka Pharmaceutical and Lundbeck present positive results showing reduced agitation in patients with Alzheimer's dementia treated with brexpiprazole at the 2022 Alzheimer's Association International Conference
- Aug 02, 2022: Otsuka Pharmaceutical and Lundbeck to present phase 3 data for brexpiprazole in patients with Alzheimer’s Dementia at AAIC 2022
- Jun 27, 2022: Otsuka, Lundbeck report positive data from Phase III Alzheimer's trial
- Jan 06, 2022: Otsuka and Lundbeck announce FDA approval of supplemental new drug application for REXULTI (brexpiprazole) to treat schizophrenia in pediatric patients ages 13-17
- Oct 13, 2021: Otsuka and Lundbeck announce FDA acceptance of supplemental new drug application; receive priority review for treatment of Schizophrenia in adolescents
- Aug 18, 2021: Results of phase 2 study of antipsychotic drug brexpiprazole for borderline personality disorder (BPD)
- Aug 18, 2021: Addition of new antipsychotic dosage form Lexarti OD Tablets obtained domestic manufacturing and marketing approval
- Aug 18, 2021: Otsuka obtains approval in Japan for orally-disintegrating-dose form of REXULTI tablets
- Aug 18, 2021: Rexulti misses mark in PII BPD trial: Otsuka
- Apr 13, 2021: Antipsychotic drug Brexpiprazole interim analysis results of a global phase 3 study for behavioral disorders (agitation) associated with Alzheimer's disease
- Apr 13, 2021: Otsuka and Lundbeck announce decision to continue phase III clinical trial evaluating brexpiprazole for treatment of agitation in patients with Alzheimer's-type dementia
- Nov 27, 2020: The Danish Business Authority (“Erhvervsstyrelsen”) requires Lundbeck to conduct a new impairment test for 2017 leading to a reversal of an impairment loss on Rexulti (brexpiprazole)
- Oct 09, 2019: ChemRar Group of Companies announces the successful completion of the second phase of clinical trials of an innovative drug for the treatment of generalized anxiety disorder
- Appendix
- Methodology
- Coverage
- Secondary Research
- Primary Research
- Expert Panel Validation
- Contact Us
- Disclaimer
- List of Tables
- Table 1: Number of Products under Development by Stage of Development, 2022
- Table 2: Number of Products under Development by Therapy Areas, 2022
- Table 3: Number of Products under Development by Indication, 2022
- Table 4: Number of Products under Development by Companies, 2022
- Table 5: Products under Development by Companies, 2022
- Table 6: Number of Products by Stage and Mechanism of Actions, 2022
- Table 7: Number of Products by Stage and Route of Administration, 2022
- Table 8: Number of Products by Stage and Molecule Type, 2022
- Table 9: Pipeline by Avineuro Pharmaceuticals Inc, 2022
- Table 10: Pipeline by Bayer AG, 2022
- Table 11: Pipeline by Denovo Biopharma LLC, 2022
- Table 12: Pipeline by Midatech Pharma Plc, 2022
- Table 13: Pipeline by Otsuka Pharmaceutical Co Ltd, 2022
- Table 14: Pipeline by SK Life Science Inc, 2022
- Table 15: Dormant Projects, 2022
- Table 16: Discontinued Products, 2022
- List of Figures
- Figure 1: Number of Products under Development by Stage of Development, 2022
- Figure 2: Number of Products under Development by Therapy Areas, 2022
- Figure 3: Number of Products under Development by Top 10 Indications, 2022
- Figure 4: Number of Products by Mechanism of Actions, 2022
- Figure 5: Number of Products by Stage and Mechanism of Actions, 2022
- Figure 6: Number of Products by Routes of Administration, 2022
- Figure 7: Number of Products by Stage and Routes of Administration, 2022
- Figure 8: Number of Products by Molecule Type, 2022
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