Fabry Disease - Epidemiology Forecast - 2032
Description
Fabry Disease - Epidemiology Forecast - 2032
DelveInsight's ‘Fabry Disease—Epidemiology Forecast—2032' report delivers an in-depth understanding of the historical and forecasted epidemiology of Fabry Disease in the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.
Fabry Disease: Disease Understanding
Fabry Disease Overview
Fabry disease is an inherited lysosomal storage disease caused by a nonfunctional or only partially functional enzyme, alpha-galactosidase A (α-gal A). Decreased activity of alpha-gal A in lysosomes results in the accumulation of enzyme substrates (Gb3 and lyso-Gb3) which cause cellular damage in tissues throughout the body.
Symptoms include pain that spreads through the body (a Fabry crisis), gastrointestinal complications, headaches, impaired sweating, vertigo, and hearing impairment.
It was once thought that Fabry disease only affected males. Females were considered only “carriers”; however, now it is known that both men and women can get Fabry disease, although it may manifest differently depending on gender. Despite being X-linked, heterozygous women may experience all the signs and symptoms of Fabry disease seen in men; although compared with hemizygous males, signs and symptoms of Fabry disease in women typically emerge at an older age and with less severity.
Fabry Disease: Epidemiology
The Fabry Disease epidemiology division provides insights into the historical and current patient pool and the forecasted trend for every seven major countries. It helps recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the report also provides the diagnosed patient pool and their trends, along with assumptions undertaken.
Key Findings
The disease epidemiology covered in the report provides historical and forecasted Fabry Disease epidemiology segmented as the prevalent cases of Fabry Disease, Gender-specific cases of Fabry Disease, Phenotype-specific cases of Fabry Disease, and Age-specific cases of Fabry Disease. The report includes the prevalent scenario of Fabry Disease in the 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom), and Japan from 2019 to 2032.
Country-wise Fabry Disease Epidemiology
The epidemiology segment also provides the Fabry Disease epidemiology data and findings across the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
The total prevalent population of Fabry Disease in the 7MM countries was estimated to be more than 13,000 cases in 2020.
As per the estimates, the United States had the highest prevalent population of Fabry Disease in 2022. Among the EU5 countries, the Germany had the highest prevalent population of Fabry Disease with approximately 1,150 cases, followed by the UK in 2020. On the other hand, Spain had the lowest, nearly 650 cases in 2020.
Scope of the Report
Fabry Disease report covers a detailed overview explaining its causes, symptoms, classification, pathophysiology, diagnosis, and treatment patterns. Fabry Disease Epidemiology Report and Model provide an overview of the risk factors and global trends of Fabry Disease in the seven major markets (7MM: US, France, Germany, Italy, Spain, UK, and Japan). The report provides insight into the historical and forecasted patient pool of Fabry Disease in seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan. The report helps recognize the growth opportunities in the 7MM concerning the patient population. The report assesses the disease risk and burden and highlights the unmet needs of Fabry Disease. The report provides the segmentation of the Fabry Disease epidemiology by prevalent cases of Fabry Disease in the 7MM. The report provides the segmentation of the Fabry Disease epidemiology by gender-specific cases of Fabry Disease in the 7MM. The report provides the segmentation of the Fabry Disease epidemiology by phenotype-specific cases of Fabry Disease in the 7MM. The report provides the Fabry Disease epidemiology segmentation by age-specific Fabry Disease cases in the 7MM.
Report Highlights
11-year Forecast of Fabry Disease epidemiology 7MM Coverage Prevalent Cases of Fabry Disease Gender-specific Cases of Fabry Disease Phenotype-specific Cases of Fabry Disease Age-specific Cases of Fabry Disease
KOL Views
We interview KOLs and obtain SME's opinions through primary research to fill the data gaps and validate our secondary research. The opinion helps understand the total patient population and current treatment pattern. This will support the clients in potential upcoming novel treatments by identifying the overall scenario of the indications.
Key Questions Answered
What major factors will drive the change in the patient population in Fabry Disease during the forecast period (2019–2032)? What are the key findings of the Fabry Disease epidemiology across 7MM, and which country will have the highest number of patients during the forecast period (2019–2032)? What would be the total number of patients with Fabry Disease across the 7MM during the forecast period (2019–2032)? Among the EU5 countries, which country will have the highest number of patients during the forecast period (2019–2032)? At what CAGR is the patient population expected to grow in the 7MM forecast period (2019–2032)? What are the disease risk, burdens, and unmet needs of Fabry Disease? What are the currently available treatments for Fabry Disease?
Reasons to buy
Fabry Disease Epidemiology report will allow the user to:
Develop business strategies by understanding the trends shaping and driving the global Fabry Disease market. Quantify patient populations in the global Fabry Disease market to improve product design, pricing, and launch plans. Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for Fabry Disease therapeutics in each market covered. Understand the magnitude of the Fabry Disease population by its prevalent cases. Understand the magnitude of the Fabry Disease population by its gender-specific cases. Understand the magnitude of the Fabry Disease population by its phenotype-specific cases. Understand the magnitude of the Fabry Disease population by its age-specific cases. The Fabry Disease epidemiology report and model were written and developed by Masters and PhD level epidemiologists. The Fabry Disease Epidemiology Model developed by DelveInsight is easy to navigate, interactive with dashboards, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports the data presented in the report and showcases disease trends over an 11-year forecast period using reputable sources.
Key Assessments
Patient Segmentation Disease Risk and Burden Risk of disease by the segmentation Factors driving growth in a specific patient population
Geographies Covered
The United States EU5 (Germany, France, Italy, Spain, and the United Kingdom) Japan
Study Period: 2019–2032
DelveInsight's ‘Fabry Disease—Epidemiology Forecast—2032' report delivers an in-depth understanding of the historical and forecasted epidemiology of Fabry Disease in the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.
Fabry Disease: Disease Understanding
Fabry Disease Overview
Fabry disease is an inherited lysosomal storage disease caused by a nonfunctional or only partially functional enzyme, alpha-galactosidase A (α-gal A). Decreased activity of alpha-gal A in lysosomes results in the accumulation of enzyme substrates (Gb3 and lyso-Gb3) which cause cellular damage in tissues throughout the body.
Symptoms include pain that spreads through the body (a Fabry crisis), gastrointestinal complications, headaches, impaired sweating, vertigo, and hearing impairment.
It was once thought that Fabry disease only affected males. Females were considered only “carriers”; however, now it is known that both men and women can get Fabry disease, although it may manifest differently depending on gender. Despite being X-linked, heterozygous women may experience all the signs and symptoms of Fabry disease seen in men; although compared with hemizygous males, signs and symptoms of Fabry disease in women typically emerge at an older age and with less severity.
Fabry Disease: Epidemiology
The Fabry Disease epidemiology division provides insights into the historical and current patient pool and the forecasted trend for every seven major countries. It helps recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the report also provides the diagnosed patient pool and their trends, along with assumptions undertaken.
Key Findings
The disease epidemiology covered in the report provides historical and forecasted Fabry Disease epidemiology segmented as the prevalent cases of Fabry Disease, Gender-specific cases of Fabry Disease, Phenotype-specific cases of Fabry Disease, and Age-specific cases of Fabry Disease. The report includes the prevalent scenario of Fabry Disease in the 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom), and Japan from 2019 to 2032.
Country-wise Fabry Disease Epidemiology
The epidemiology segment also provides the Fabry Disease epidemiology data and findings across the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
The total prevalent population of Fabry Disease in the 7MM countries was estimated to be more than 13,000 cases in 2020.
As per the estimates, the United States had the highest prevalent population of Fabry Disease in 2022. Among the EU5 countries, the Germany had the highest prevalent population of Fabry Disease with approximately 1,150 cases, followed by the UK in 2020. On the other hand, Spain had the lowest, nearly 650 cases in 2020.
Scope of the Report
Report Highlights
KOL Views
We interview KOLs and obtain SME's opinions through primary research to fill the data gaps and validate our secondary research. The opinion helps understand the total patient population and current treatment pattern. This will support the clients in potential upcoming novel treatments by identifying the overall scenario of the indications.
Key Questions Answered
Reasons to buy
Fabry Disease Epidemiology report will allow the user to:
Key Assessments
Geographies Covered
Study Period: 2019–2032
Table of Contents
90 Pages
- 1. Key Insights
- 2. Report Introduction
- 3. Executive Summary of Fabry Disease
- 4. Disease Background and Overview
- 4.1. Introduction
- 4.2. Classification
- 4.3. Signs and Symptoms
- 4.4. Etiology
- 4.5. Inheritance Pattern
- 4.6. Genetics
- 4.7. Molecular Basis
- 4.8. Pathogenesis
- 4.9. Diagnosis
- 4.9.1. European Fabry Working Group (EFWG): Diagnostic criteria
- 4.9.2. Challenges in Diagnosis
- 4.10. Treatment and Management of Fabry Disease
- 4.10.1. Guidelines for the Management of Fabry Disease
- 4.10.2. Croatian Society: Recommendation for the treatment of Fabry Disease
- 4.10.3. Treatment Practices
- 4.10.4. Consensus recommendations for diagnosis, management, and treatment of Fabry disease in pediatric patients
- 5. Epidemiology and Patient Population
- 5.1. Key Findings
- 5.2. 7MM Total Prevalence of Fabry Disease
- 5.3. Epidemiology of Fabry Disease
- 5.4. The United States
- 5.4.1. Prevalence of Fabry Disease in the United States
- 5.4.2. Gender-specific cases of Fabry Disease in the United States
- 5.4.3. Phenotype-specific cases of Fabry Disease in the United States
- 5.4.4. Age-specific cases of Fabry Disease in the United States
- 5.5. EU5
- 5.5.1. Total Prevalence of Fabry Disease in EU5
- 5.5.2. Germany
- 5.5.2.1. Gender-specific cases of Fabry Disease in Germany
- 5.5.2.2. Phenotype-specific cases of Fabry Disease in Germany
- 5.5.2.3. Age-specific cases of Fabry Disease in Germany
- 5.5.3. France
- 5.5.3.1. Gender-specific cases of Fabry Disease in France
- 5.5.3.2. Phenotype-specific cases of Fabry Disease in France
- 5.5.3.3. Age-specific cases of Fabry Disease in France
- 5.5.4. Italy
- 5.5.4.1. Gender-specific cases of Fabry Disease in Italy
- 5.5.4.2. Phenotype-specific cases of Fabry Disease in Italy
- 5.5.4.3. Age-specific cases of Fabry Disease in Italy
- 5.5.5. Spain
- 5.5.5.1. Gender-specific cases of Fabry Disease in Spain
- 5.5.5.2. Phenotype-specific cases of Fabry Disease in Spain
- 5.5.5.3. Age-specific cases of Fabry Disease in Spain
- 5.5.6. The United Kingdom
- 5.5.6.1. Gender-specific cases of Fabry Disease in the United Kingdom
- 5.5.6.2. Phenotype-specific cases of Fabry Disease in the United Kingdom
- 5.5.6.3. Age-specific cases of Fabry Disease in the United Kingdom
- 5.5.7. Japan
- 5.5.7.1. Prevalence of Fabry Disease in Japan
- 5.5.7.2. Gender-specific cases of Fabry Disease in Japan
- 5.5.7.3. Phenotype-specific cases of Fabry Disease in Japan
- 5.5.7.4. Age-specific cases of Fabry Disease in Japan
- 6. Patient Journey
- 7. KOL Views
- 8. Unmet Needs
- 9. Appendix
- 9.1. Bibliography
- 9.2. Report Methodology
- 10. DelveInsight Capabilities
- 11. Disclaimer
- 12. About DelveInsight
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