Complicated Urinary Tract Infections - Epidemiology Forecast - 2034
Description
Key Highlights
cUTIs are severe infections of the urinary system that typically occur in individuals with underlying health conditions such as diabetes, kidney disease, or urinary tract abnormalities.
Unlike uncomplicated UTIs, which affect healthy individuals, cUTIs are associated with a higher risk of treatment failure, recurrent infections, and complications like sepsis. Common pathogens responsible for cUTIs include Uropathogenic Escherichia coli, Klebsiella pneumonia, and other multidrug-resistant bacteria.
In 2024, approximately 8.3 million individuals were diagnosed with incident cases of cUTI across the 7MM, reflecting a substantial burden and reflecting the need for effective infection control strategies.
Gender-specific analysis revealed a significant female predominance in cUTI diagnoses across the 7MM in 2024, with women accounting for roughly 70% of cases and men comprising around 30%—highlighting gender-based vulnerability to urinary infections.
DelveInsight’s analysis showed that Japan accounted for approximately 1.3 million diagnosed incident cases of cUTI in 2024, positioning it as a key contributor to the overall disease landscape within the 7MM.
In 2024, Germany reported the highest number of diagnosed incident cUTI cases among the EU4 and the UK, with approximately 880 thousand individuals affected, pointing to a prominent burden within the country’s healthcare system.
In summary, the epidemiological landscape of cUTI across the 7MM reveals a significant clinical burden, with notable gender disparity and country-specific variation—underscoring the urgent need for targeted prevention strategies, early diagnosis, and optimized treatment approaches.
DelveInsight’s “Complicated Urinary Tract Infection – Epidemiology Forecast – 2034” report delivers an in-depth understanding of cUTI historical and forecasted epidemiology in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.
Complicated Urinary Tract Infection: Disease Understanding
Complicated Urinary Tract Infection Overview,
cUTI poses a higher risk of treatment failure due to underlying factors such as structural abnormalities, resistant pathogens, or comorbidities like diabetes. Timely and accurate identification is essential, as these infections often demand prolonged therapy, tailored antibiotic selection, and thorough diagnostic workups. Failure to recognize and manage them appropriately can lead to persistent infection, renal damage, or even systemic complications—making early intervention critical for favorable outcomes.
cUTI leads to inflammation of the urinary tract lining, causing symptoms such as pelvic or abdominal pain, pressure in the lower pelvis, painful urination (dysuria), frequent or urgent urination, incontinence, and the need to urinate at night. Other signs include cloudy or foul-smelling urine, blood in the urine, pain during sex, penile or flank pain, fatigue, fever with chills, vomiting, and in some cases, mental confusion—especially in older adults..
cUTIs are typically caused by a broader spectrum of pathogens, including E. coli, Klebsiella, Pseudomonas, Enterococcus, and Staphylococcus species. In high-risk populations—such as diabetics, catheterized patients, and the immunocompromised—Candida may also be involved. The wide range of organisms and increasing multidrug resistance make pathogen-specific treatment essential in cUTIs.
Complicated Urinary Tract Infection Diagnosis
Diagnosis of a cUTI is based on three main features: the clinical picture, microbiological tests, and radiological investigations.
Clinical Picture: The most common clinical presentations of UTI include acute cystitis, pyelonephritis, and less commonly acute prostatitis, but patients with abnormal urinary tracts can present more atypically.
Laboratory Tests: Basic laboratory tests may reveal elevated inflammatory markers, and renal function should be recorded. The urine dipstick is a simple and cheap bedside test and is very useful in confirming a diagnosis of UTI.
Radiological Tests: All patients with cUTIs, including first-time pyelonephritis in healthy nonpregnant women, should undergo renal ultrasound to assess for obstruction or abnormalities, as these cannot be reliably excluded by clinical evaluation alone.
Complicated Urinary Tract Infection Epidemiology
The cUTI epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by total diagnosed incident cases of cUTI, age-specific cases of cUTI, gender-specific cases of cUTI, and pathogen-specific cases of cUTI, in the 7MM covering the United States, EU4 countries (Germany, France, Italy, and Spain), United Kingdom, and Japan from 2020 to 2034.
In 2024, the United Statdes recorded approximately 3.5 million diagnosed incident cases of cUTI, highlighting its position as the leading contributor to the overall cUTI burden within the 7MM.
In 2024, the highest number of cUTI cases in the US was observed in the 65–84 years age group, with approximately 1.7 million cases, followed by the =85 years group with around 730 thousand cases. In contrast, the lowest burden was reported in the 0–17 years age group, with just 40 thousand cases.
In 2024, females accounted for approximately 70% of diagnosed cUTI cases in the United States, while males made up around 30%—underscoring a significant gender disparity likely influenced by anatomical and hormonal factors that predispose women to urinary tract infections more frequently than men.
In 2024, Uropathogenic Escherichia coli (UPEC) was the leading cause of cUTI in the EU4 and the UK, accounting for approximately 2.2 million cases. This was followed by Klebsiella pneumoniae with around 275 thousand cases and Enterococcus spp. with nearly 380 thousand cases, highlighting their prominent role in the regional cUTI burden.
KOL Views
To gaze into the epidemiology insights of the real world, we take KOLs and SMEs’ opinions working in the domain through primary research to fill the data gaps and validate our secondary research on disease incidence.
DelveInsight’s analysts connected with 20+ KOLs to gather insights; however, interviews were conducted with 10+ KOLs in the 7MM. Centers such as the Johns Hopkins Hospital, USA, US; University Medicine Essen - Ruhrlandklinik, Germany; Institut Curi, France; Università Politecnica delle Marche Home, Italy; Arnau de Vilanova University Hospital, Spain; Royal Brompton and Harefield hospitals Trust, UK; National Center for Global Health and Medicine, Japan and others were contacted. Their opinion helps understand and validate current disease prevalence, gender involved with the disease, diagnosis rate, and diagnostic criteria.
Scope of the Report
The report covers a segment of an executive summary, and a descriptive overview cUTI explaining its causes, signs and symptoms, pathogenesis.
Comprehensive insight into the epidemiology segments and forecasts, the future growth potential of diagnosis rate, and disease progression have been provided.
A detailed review of current challenges in establishing diagnosis and diagnosis rate is provided.
Complicated Urinary Tract Infection Report Insights
Patient Population
Country-wise Epidemiology Distribution
Complicated Urinary Tract Infection Report Key Strengths
Ten-year Forecast
The 7MM Coverage
cUTI Epidemiology Segmentation
Complicated Urinary Tract Infection Report Assessment
Epidemiology Segmentation
Current Diagnostic Practices
FAQs
Epidemiology Insights
What are the disease risks, burdens, and unmet needs of cUTI? What will be the growth opportunities across the 7MM with respect to the patient population pertaining to cUTI
What is the historical and forecasted cUTI patient pool in the United States, EU4 (Germany, France, Italy, Spain) and the United Kingdom, and Japan?
What is the diagnostic pattern of cUTI?
Which clinical factors will affect cUTI?
Which factors will affect the increase in the diagnosis of cUTI?
Reasons to buy
Insights on disease burden, details regarding diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
To understand the change in cUTI cases in varying geographies over the coming years.
? A detailed overview of total diagnosed incident cases of cUTI, age-specific cases of cUTI, gender-specific cases of cUTI, and pathogen-specific cases of cUTI, is included.
Detailed insights on various factors hampering disease diagnosis and other existing diagnostic challenges.
cUTIs are severe infections of the urinary system that typically occur in individuals with underlying health conditions such as diabetes, kidney disease, or urinary tract abnormalities.
Unlike uncomplicated UTIs, which affect healthy individuals, cUTIs are associated with a higher risk of treatment failure, recurrent infections, and complications like sepsis. Common pathogens responsible for cUTIs include Uropathogenic Escherichia coli, Klebsiella pneumonia, and other multidrug-resistant bacteria.
In 2024, approximately 8.3 million individuals were diagnosed with incident cases of cUTI across the 7MM, reflecting a substantial burden and reflecting the need for effective infection control strategies.
Gender-specific analysis revealed a significant female predominance in cUTI diagnoses across the 7MM in 2024, with women accounting for roughly 70% of cases and men comprising around 30%—highlighting gender-based vulnerability to urinary infections.
DelveInsight’s analysis showed that Japan accounted for approximately 1.3 million diagnosed incident cases of cUTI in 2024, positioning it as a key contributor to the overall disease landscape within the 7MM.
In 2024, Germany reported the highest number of diagnosed incident cUTI cases among the EU4 and the UK, with approximately 880 thousand individuals affected, pointing to a prominent burden within the country’s healthcare system.
In summary, the epidemiological landscape of cUTI across the 7MM reveals a significant clinical burden, with notable gender disparity and country-specific variation—underscoring the urgent need for targeted prevention strategies, early diagnosis, and optimized treatment approaches.
DelveInsight’s “Complicated Urinary Tract Infection – Epidemiology Forecast – 2034” report delivers an in-depth understanding of cUTI historical and forecasted epidemiology in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.
Complicated Urinary Tract Infection: Disease Understanding
Complicated Urinary Tract Infection Overview,
cUTI poses a higher risk of treatment failure due to underlying factors such as structural abnormalities, resistant pathogens, or comorbidities like diabetes. Timely and accurate identification is essential, as these infections often demand prolonged therapy, tailored antibiotic selection, and thorough diagnostic workups. Failure to recognize and manage them appropriately can lead to persistent infection, renal damage, or even systemic complications—making early intervention critical for favorable outcomes.
cUTI leads to inflammation of the urinary tract lining, causing symptoms such as pelvic or abdominal pain, pressure in the lower pelvis, painful urination (dysuria), frequent or urgent urination, incontinence, and the need to urinate at night. Other signs include cloudy or foul-smelling urine, blood in the urine, pain during sex, penile or flank pain, fatigue, fever with chills, vomiting, and in some cases, mental confusion—especially in older adults..
cUTIs are typically caused by a broader spectrum of pathogens, including E. coli, Klebsiella, Pseudomonas, Enterococcus, and Staphylococcus species. In high-risk populations—such as diabetics, catheterized patients, and the immunocompromised—Candida may also be involved. The wide range of organisms and increasing multidrug resistance make pathogen-specific treatment essential in cUTIs.
Complicated Urinary Tract Infection Diagnosis
Diagnosis of a cUTI is based on three main features: the clinical picture, microbiological tests, and radiological investigations.
Clinical Picture: The most common clinical presentations of UTI include acute cystitis, pyelonephritis, and less commonly acute prostatitis, but patients with abnormal urinary tracts can present more atypically.
Laboratory Tests: Basic laboratory tests may reveal elevated inflammatory markers, and renal function should be recorded. The urine dipstick is a simple and cheap bedside test and is very useful in confirming a diagnosis of UTI.
Radiological Tests: All patients with cUTIs, including first-time pyelonephritis in healthy nonpregnant women, should undergo renal ultrasound to assess for obstruction or abnormalities, as these cannot be reliably excluded by clinical evaluation alone.
Complicated Urinary Tract Infection Epidemiology
The cUTI epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by total diagnosed incident cases of cUTI, age-specific cases of cUTI, gender-specific cases of cUTI, and pathogen-specific cases of cUTI, in the 7MM covering the United States, EU4 countries (Germany, France, Italy, and Spain), United Kingdom, and Japan from 2020 to 2034.
In 2024, the United Statdes recorded approximately 3.5 million diagnosed incident cases of cUTI, highlighting its position as the leading contributor to the overall cUTI burden within the 7MM.
In 2024, the highest number of cUTI cases in the US was observed in the 65–84 years age group, with approximately 1.7 million cases, followed by the =85 years group with around 730 thousand cases. In contrast, the lowest burden was reported in the 0–17 years age group, with just 40 thousand cases.
In 2024, females accounted for approximately 70% of diagnosed cUTI cases in the United States, while males made up around 30%—underscoring a significant gender disparity likely influenced by anatomical and hormonal factors that predispose women to urinary tract infections more frequently than men.
In 2024, Uropathogenic Escherichia coli (UPEC) was the leading cause of cUTI in the EU4 and the UK, accounting for approximately 2.2 million cases. This was followed by Klebsiella pneumoniae with around 275 thousand cases and Enterococcus spp. with nearly 380 thousand cases, highlighting their prominent role in the regional cUTI burden.
KOL Views
To gaze into the epidemiology insights of the real world, we take KOLs and SMEs’ opinions working in the domain through primary research to fill the data gaps and validate our secondary research on disease incidence.
DelveInsight’s analysts connected with 20+ KOLs to gather insights; however, interviews were conducted with 10+ KOLs in the 7MM. Centers such as the Johns Hopkins Hospital, USA, US; University Medicine Essen - Ruhrlandklinik, Germany; Institut Curi, France; Università Politecnica delle Marche Home, Italy; Arnau de Vilanova University Hospital, Spain; Royal Brompton and Harefield hospitals Trust, UK; National Center for Global Health and Medicine, Japan and others were contacted. Their opinion helps understand and validate current disease prevalence, gender involved with the disease, diagnosis rate, and diagnostic criteria.
Scope of the Report
The report covers a segment of an executive summary, and a descriptive overview cUTI explaining its causes, signs and symptoms, pathogenesis.
Comprehensive insight into the epidemiology segments and forecasts, the future growth potential of diagnosis rate, and disease progression have been provided.
A detailed review of current challenges in establishing diagnosis and diagnosis rate is provided.
Complicated Urinary Tract Infection Report Insights
Patient Population
Country-wise Epidemiology Distribution
Complicated Urinary Tract Infection Report Key Strengths
Ten-year Forecast
The 7MM Coverage
cUTI Epidemiology Segmentation
Complicated Urinary Tract Infection Report Assessment
Epidemiology Segmentation
Current Diagnostic Practices
FAQs
Epidemiology Insights
What are the disease risks, burdens, and unmet needs of cUTI? What will be the growth opportunities across the 7MM with respect to the patient population pertaining to cUTI
What is the historical and forecasted cUTI patient pool in the United States, EU4 (Germany, France, Italy, Spain) and the United Kingdom, and Japan?
What is the diagnostic pattern of cUTI?
Which clinical factors will affect cUTI?
Which factors will affect the increase in the diagnosis of cUTI?
Reasons to buy
Insights on disease burden, details regarding diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
To understand the change in cUTI cases in varying geographies over the coming years.
? A detailed overview of total diagnosed incident cases of cUTI, age-specific cases of cUTI, gender-specific cases of cUTI, and pathogen-specific cases of cUTI, is included.
Detailed insights on various factors hampering disease diagnosis and other existing diagnostic challenges.
Table of Contents
121 Pages
- 1. Key Insights
- 2. Report Introduction
- 3. Complicated Urinary Tract Infection (cUTI) Patient Overview at a Glance
- 3.1. Patient Share Distribution (%) in the 7MM in 2024
- 3.2. Patient Share Distribution (%) in the 7MM in 2034
- 4. Executive Summary
- 5. Epidemiology Forecast Methodology
- 6. Disease Background and Overview
- 6.1. Introduction
- 6.2. Signs and Symptoms
- 6.3. Causes
- 6.4. Diagnosis and Differential Diagnosis
- 6.4.1. Diagnostic Algorithm
- 6.4.2. Differential Diagnosis
- 6.4.3. Diagnostic Guidelines
- 7. Epidemiology and Patient Population
- 7.1. Key Findings
- 7.2. Assumptions and Rationale
- 7.3. Total Diagnosed Incident Cases of cUTI in the 7MM
- 7.5. The United States
- 7.5.1. Total Diagnosed Incident Cases of cUTI in the United States
- 7.5.2. Age-specific Cases of cUTI in the United States
- 7.5.3. Gender-specific Cases of cUTI in the United States
- 7.5.4. Pathogen-specific Cases of cUTI in the United States
- 7.6. EU4 and the UK
- 7.6.1. Total Diagnosed Incident Cases of cUTI in EU4 and the UK
- 7.6.2. Age-specific Cases of cUTI in EU4 and the UK
- 7.6.3. Gender-specific Cases of cUTI in EU4 and the UK
- 7.6.4. Pathogen-specific Cases of cUTI in EU4 and the UK
- 7.7. Japan
- 7.7.1. Total Diagnosed Incident Cases of cUTI in Japan
- 7.7.2. Age-specific Cases of cUTI in Japan
- 7.7.3. Gender-specific Cases of cUTI in Japan
- 7.7.4. Pathogen-specific Cases of cUTI in Japan
- 8. KOL Views
- 9. Appendix
- 9.1. Acronyms and Abbreviations
- 9.2. Bibliography
- 9.3. Report Methodology
- 11. DelveInsight Capabilities
- 12. Disclaimer
- 13. About DelveInsight
Pricing
Currency Rates
Questions or Comments?
Our team has the ability to search within reports to verify it suits your needs. We can also help maximize your budget by finding sections of reports you can purchase.
