Oligonucleotides are commonly used as primers for polymerase chain reaction (PCR), PCR assays, and panels for biologically related genes. Antisense oligonucleotides are used to reduce levels of protein synthesis by inhibiting mRNA processing or translation. Other uses of oligonucleotides include DNA sequencing, DNA microarrays, fluorescence in situ hybridization (FISH), and nucleic acid aptamers. Moreover, many pharmaceutical companies are focusing on developing nucleic acid-based therapeutics due to which the demand of oligonucleotide is increasing. Hence, market players are focusing on expanding their manufacturing facilities, which is expected to boost the market growth over the forecast period. For instance, in August 2020, Agilent Technologies Inc., announced the expansion of its state-of-the-art production facility in Frederick, Colorado, which develops manufactures oligos that hold potential to be used as treatments for diseases such as COVID-19, cardiovascular disease, cancer, rare and infectious diseases, and other conditions.
Market Dynamics:
Key players are focusing on various inorganic growth strategies such as collaborations, partnerships and agreements, which is expected to propel the growth of the global oligonucleotide synthesis market during the forecast period. For instance, on August 05, 2020, Evotec SE, a drug discovery and development company entered into a strategic partnership with Secarna Pharmaceuticals GmbH & Co. KG, a drug discovery company, for the development of antisense oligonucleotide therapies.
Moreover, in November 2019, CSBio, a peptide and instrumentation manufacturing company entered into a collaboration with Sunresin, a supplier of ion exchange resin and absorption & separation resin for the development of an optimized polystyrene resin for commercial scale oligonucleotide synthesis.
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