Precision Medicine Global Market Opportunities And Strategies To 2030: COVID-19 Growth And Change

Best Price Guarantee	Length	Publisher	Published Date	SKU
from $5,000	260 Pages	The Business Research Company	June, 2022	BRC17251669

Best Price Guarantee
Price	from $5,000
Length	260 Pages
Publisher	The Business Research Company
Published Date	June, 2022
SKU	BRC17251669

Precision Medicine Global Market Opportunities And Strategies To 2030: COVID-19 Growth And Change

Precision Medicine Global Market Opportunities And Strategies To 2030: COVID-19 Growth And Change from The Business Research Company provides the strategists; marketers and senior management with the critical information they need to assess the global precision medicine market as it emerges from the COVID 19 shut down.

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Description:

Where is the largest and fastest growing market for the precision medicine? How does the market relate to the overall economy; demography and other similar markets? What forces will shape the market going forward? The precision medicine market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics; size and growth; segmentation; regional and country breakdowns; competitive landscape; market shares; trends and strategies for this market. It traces the market’s historic and forecast market growth by geography. It places the market within the context of the wider precision medicine market; and compares it with other markets.

The report covers the following chapters

Executive Summary – The executive summary section of the report gives a brief overview and summary of the report

Report Structure – This section gives the structure of the report and the information covered in the various sections.

Introduction – The introduction section of the report gives brief introduction about segmentation by geography, segmentation by technology, segmentation by application and segmentation by end-use.

Market Characteristics – The market characteristics section of the report defines and explains the precision medicine market. This chapter also defines and describes goods and related services covered in the report.

Trends And Strategies – This chapter describes the major trends shaping the global precision medicine market. This section highlights likely future developments in the market and suggests approaches companies can take to exploit these opportunities.

Impact Of COVID-19 – This chapter discusses the impact of COVID-19 on the precision medicine market.

Global Market Size And Growth – This section contains the global historic (2015-2020) and forecast (2020-2025), and (2025-2030) market values, and drivers and restraints that support and control the growth of the market in the historic and forecast periods.

Regional Analysis – This section contains the historic (2015-2020) and forecast (2020-2025), and (2025-2030) market values and growth and market share comparison by region.

Segmentation – This section contains the market values (2015-2030) and analysis for different segments.

Regional Market Size and Growth – This section contains the region’s market size (2020), historic (2015-2020) and forecast (2020-2025), and (2025-2030) market values, and growth and market share comparison of countries within the region. This report includes information on all the regions Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa and major countries within each region. The market overview sections of the report describe the current size of the market, background information, government initiatives, regulations, regulatory bodies, associations, corporate tax structure, investments, and major companies.

Competitive Landscape – This section covers details on the competitive landscape of the global precision medicine market, estimated market shares and company profiles for the leading players.

Key Mergers And Acquisitions – This chapter gives the information on recent mergers and acquisitions in the market covered in the report. This section gives key financial details of mergers and acquisitions which have shaped the market in recent years.

Opportunities And Strategies – This section gives information on growth opportunities across countries, segments and strategies to be followed in those markets. It gives an understanding of where there is significant business to be gained by competitors in the next five years.

Conclusions And Recommendations – This section includes conclusions and recommendations based on findings of the research. This section also gives recommendations for precision medicine manufacturing companies in terms of product offerings, geographic expansion, price offerings, and target groups.

Appendix – This section includes details on the NAICS codes covered, abbreviations and currencies codes used in this report.

Scope

Markets Covered: 1) By Technology: Big Data Analytics; Bioinformatics; Gene Sequencing; Drug Discovery; Companion Diagnostics; Other Technology

2) By Application: Oncology; Respiratory Diseases; Central Nervous System Disorders; Immunology; Genetic Diseases; Other Applications

3) By End-Use: Pharmaceutical Companies; Diagnostic Companies; Healthcare And IT Firms; Others

Companies Mentioned: Quest Diagnostics; Thermo Fisher Scientific Inc.; Roche Holding AG; Medtronic plc.; Novartis AG

Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Russia; South Korea; UK; USA

Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa

Time series: Five years historic and ten years forecast.

Data: Ratios of market size and growth to related markets; GDP proportions; expenditure per capita; precision medicine indicators comparison.

Data segmentations: country and regional historic and forecast data; market share of competitors; market segments.

Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.

1. Precision Medicine Market Executive Summary
2. Table of Contents
3. List of Figures
4. List of Tables
5. Report Structure
6. Introduction: 6.1. Segmentation By Geography; 6.2. Segmentation By Technology; 6.3. Segmentation By Application; 6.4. Segmentation By End-Use
7. Precision Medicine Market Characteristics: 7.1. Market Definition; 7.2. Segmentation By Technology; 7.2.1. Big Data Analytics; 7.2.2. Bioinformatics; 7.2.3. Gene Sequencing; 7.2.4. Drug Discovery; 7.2.5. Companion Diagnostics; 7.2.6. Other Technology; 7.3. Segmentation By Application; 7.3.1. Oncology; 7.3.2. Respiratory Diseases; 7.3.3. Central Nervous System Disorders; 7.3.4. Immunology; 7.3.5. Genetic Diseases; 7.3.6. Other Applications; 7.4. Segmentation By End-Use; 7.4.1. Pharmaceutical Companies; 7.4.2. Diagnostic Companies; 7.4.3. Healthcare And IT Firms; 7.4.4. Others
8. Precision Medicine Market Trends And Strategies: 8.1. Use Of Artificial Intelligence Technology In Precision Medicine; 8.2. Expansion Of Precision Medicine To Immune-Mediated Diseases; 8.3. New Research And Development Initiatives; 8.4. Increasing Collaborations And Partnerships
9. Impact Of COVID-19 On The Precision Medicine Market: 9.1. Introduction; 9.2. Use Of Precision Medicine For COVID-19 Treatment; 9.3. Impact On Companies; 9.4. Future Outlook
10. Global Precision Medicine Market Size And Growth: 10.1. Market Size; 10.2. Historic Market Growth, 2015 – 2020, Value ($ Million); 10.2.1. Drivers Of The Market 2015 – 2020; 10.2.2. Restraints On The Market 2015 – 2020; 10.3. Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 10.3.1. Drivers Of The Market 2020 – 2025; 10.3.2. Restraints On The Market 2020 – 2025
11. Global Precision Medicine Market Segmentation: 11.1. Global Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 11.2. Global Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 11.3. Global Precision Medicine Market, Segmentation By Application, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million)
12. Precision Medicine Market, Regional And Country Analysis: 12.1. Global Precision Medicine Market, By Region, Historic and Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 12.2. Global Precision Medicine Market, By Country, Historic and Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million)
13. Asia-Pacific Precision Medicine Market: 13.1. Asia-Pacific Precision Medicine Market Overview; 13.1.1. Region Information; 13.1.2. Market Information; 13.1.3. Background Information; 13.1.4. Government Initiatives; 13.1.5. Regulations; 13.1.6. Regulatory Bodies; 13.1.7. Major Associations; 13.1.8. Taxes Levied; 13.1.9. Corporate Tax Structure; 13.1.10. Investments; 13.1.11. Major Companies; 13.2. Asia-Pacific Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 13.3. Asia-Pacific Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 13.4. Asia-Pacific Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 13.5. Asia-Pacific Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 13.6. Asia-Pacific Precision Medicine Market: Country Analysis; 13.7. China Precision Medicine Market; 13.8. China Precision Medicine Market Overview; 13.8.1. Country Information; 13.8.2. Market Information; 13.8.3. Background Information; 13.8.4. Government Initiatives; 13.8.5. Regulations; 13.8.6. Regulatory Bodies; 13.8.7. Major Associations; 13.8.8. Taxes Levied; 13.8.9. Corporate Tax Structure; 13.8.10. Investments; 13.8.11. Major Companies; 13.9. China Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 13.10. China Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 13.11. China Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 13.12. China Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 13.13. India Precision Medicine Market; 13.14. India Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 13.15. India Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 13.16. India Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 13.17. India Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 13.18. Japan Precision Medicine Market; 13.19. Japan Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 13.20. Japan Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 13.21. Japan Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 13.22. Japan Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 13.23. Australia Precision Medicine Market; 13.24. Australia Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 13.25. Australia Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 13.26. Australia Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 13.27. Australia Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 13.28. Indonesia Precision Medicine Market; 13.29. Indonesia Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 13.30. Indonesia Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 13.31. Indonesia Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 13.32. Indonesia Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 13.33. South Korea Precision Medicine Market; 13.34. South Korea Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 13.35. South Korea Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 13.36. South Korea Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 13.37. South Korea Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million)
14. Western Europe Precision Medicine Market: 14.1. Western Europe Precision Medicine Market Overview; 14.1.1. Region Information; 14.1.2. Market Information; 14.1.3. Background Information; 14.1.4. Government Initiatives; 14.1.5. Regulations; 14.1.6. Regulatory Bodies; 14.1.7. Associations; 14.1.8. Taxes Levied; 14.1.9. Corporate Tax Structure; 14.1.10. Investments; 14.1.11. Major Companies; 14.2. Western Europe Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 14.3. Western Europe Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 14.4. Western Europe Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 14.5. Western Europe Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 14.6. Western Europe Precision Medicine Market: Country Analysis; 14.7. UK Precision Medicine Market; 14.8. UK Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 14.9. UK Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 14.10. UK Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 14.11. UK Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 14.12. Germany Precision Medicine Market; 14.13. Germany Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 14.14. Germany Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 14.15. Germany Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 14.16. Germany Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 14.17. France Precision Medicine Market; 14.18. France Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 14.19. France Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 14.20. France Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 14.21. France Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million)
15. Eastern Europe Precision Medicine Market: 15.1. Eastern Europe Precision Medicine Market Overview; 15.1.1. Region Information; 15.1.2. Market Information; 15.1.3. Background Information; 15.1.4. Government Initiatives; 15.1.5. Regulations; 15.1.6. Regulatory Bodies; 15.1.7. Major Associations; 15.1.8. Taxes Levied; 15.1.9. Corporate Tax Structure; 15.1.10. Investments; 15.1.11. Major Companies; 15.2. Eastern Europe Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 15.3. Eastern Europe Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 15.4. Eastern Europe Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 15.5. Eastern Europe Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 15.6. Eastern Europe Precision Medicine Market: Country Analysis; 15.7. Russia Precision Medicine Market; 15.8. Russia Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 15.9. Russia Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 15.10. Russia Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 15.11. Russia Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million)
16. North America Precision Medicine Market: 16.1. North America Precision Medicine Market Overview; 16.1.1. Region Information; 16.1.2. Market Information; 16.1.3. Background Information; 16.1.4. Government Initiatives; 16.1.5. Regulations; 16.1.6. Regulatory Bodies; 16.1.7. Major Associations; 16.1.8. Taxes Levied; 16.1.9. Corporate Tax Structure; 16.1.10. Investments; 16.1.11. Major Companies; 16.2. North America Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 16.3. North America Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 16.4. North America Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 16.5. North America Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 16.6. North America Precision Medicine Market: Country Analysis; 16.7. USA Precision Medicine Market; 16.8. USA Precision Medicine Market Overview; 16.8.1. Country Information; 16.8.2. Market Information; 16.8.3. Background Information; 16.8.4. Government Initiatives; 16.8.5. Regulations; 16.8.6. Regulatory Bodies; 16.8.7. Major Associations; 16.8.8. Taxes levied; 16.8.9. Corporate Tax Structure; 16.8.10. Investments; 16.8.11. Major Companies; 16.9. USA Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 16.10. USA Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 16.11. USA Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 16.12. USA Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million)
17. South America Precision Medicine Market: 17.1. South America Precision Medicine Market Overview; 17.1.1. Region Information; 17.1.2. Market Information; 17.1.3. Background Information; 17.1.4. Government Initiatives; 17.1.5. Regulations; 17.1.6. Regulatory Bodies; 17.1.7. Major Associations; 17.1.8. Taxes Levied; 17.1.9. Corporate Tax Structure; 17.1.10. Major Companies; 17.2. South America Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 17.3. South America Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 17.4. South America Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 17.5. South America Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 17.6. South America Precision Medicine Market: Country Analysis; 17.7. Brazil Precision Medicine Market; 17.8. Brazil Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 17.9. Brazil Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 17.10. Brazil Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 17.11. Brazil Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million)
18. Middle East Precision Medicine Market: 18.1. Middle East Precision Medicine Market Overview; 18.1.1. Region Information; 18.1.2. Market Information; 18.1.3. Background Information; 18.1.4. Government Initiatives; 18.1.5. Regulations; 18.1.6. Regulatory Bodies; 18.1.7. Major Associations; 18.1.8. Taxes levied; 18.1.9. Corporate Tax Structure; 18.1.10. Investments; 18.1.11. Major Companies; 18.2. Middle East Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 18.3. Middle East Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 18.4. Middle East Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 18.5. Middle East Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million)
19. Africa Precision Medicine Market: 19.1. Africa Precision Medicine Market Overview; 19.1.1. Region Information; 19.1.2. Market Information; 19.1.3. Background Information; 19.1.4. Government Initiatives; 19.1.5. Regulations; 19.1.6. Regulatory Bodies; 19.1.7. Major Associations; 19.1.8. Taxes Levied; 19.1.9. Corporate Tax Structure; 19.1.10. Investments; 19.1.11. Major Companies; 19.2. Africa Precision Medicine Market, Historic Market Growth, 2015 – 2020, Value ($ Million); 19.3. Africa Precision Medicine Market, Forecast Market Growth, 2020 – 2025, 2030F Value ($ Million); 19.4. Africa Precision Medicine Market, Segmentation By Technology, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million); 19.5. Africa Precision Medicine Market, Segmentation By End-Use, Historic And Forecast, 2015 – 2020, 2025F, 2030F, Value ($ Million)
20. Precision Medicine Global Market Competitive Landscape And Company Profiles: 20.1. Company Profiles; 20.2. Quest Diagnostics; 20.2.1. Company Overview; 20.2.2. Products And Services; 20.2.3. Business Strategy; 20.2.4. Financial Overview; 20.3. Thermo Fisher Scientific Inc.; 20.3.1. Company Overview; 20.3.2. Products And Services; 20.3.3. Business Strategy; 20.3.4. Financial Overview; 20.4. Roche Holding AG; 20.4.1. Company Overview; 20.4.2. Products And Services; 20.4.3. Business Strategy; 20.4.4. Financial Overview; 20.5. Medtronic plc; 20.5.1. Company Overview; 20.5.2. Products And Services; 20.5.3. Business Strategy; 20.5.4. Financial Overview; 20.6. Novartis AG; 20.6.1. Company Overview; 20.6.2. Products And Services; 20.6.3. Business Strategy; 20.6.4. Financial Overview
21. Key Mergers And Acquisitions In The Precision Medicine Market: 21.1. 2bPrecise Acquired By AccessDX; 21.2. GE Healthcare Acquired Zionexa; 21.3. Servier Laboratories Acquired Agios Pharmaceuticals; 21.4. Agilent Technologies Acquired Resolution Bioscience; 21.5. Precision Medicine Group Acquired Project Farma; 21.6. Blackstone Acquires Precision Medicine Group; 21.7. Roche Acquired Foundation Medicine; 21.8. Konica Minolta Acquired Invicro
22. Precision Medicine Market Opportunities & Strategies: 22.1. Global Precision Medicine Market In 2025 – Countries Offering Most New Opportunities; 22.2. Global Precision Medicine Market In 2025 – Segments Offering Most New Opportunities; 22.3. Global Precision Medicine Market In 2025 – Growth Strategies; 22.3.1. Market Trend Based Strategies; 22.3.2. Competitor Strategies
23. Precision Medicine Market, Conclusions And Recommendations: 23.1. Conclusions; 23.2. Recommendations; 23.2.1. Product; 23.2.2. Place; 23.2.3. Price; 23.2.4. Promotion; 23.2.5. People
24. Appendix: 24.1. Market Data Sources; 24.2. Research Methodology; 24.3. Currencies; 24.4. Research Inquiries; 24.5. The Business Research Company; 24.6. Copyright and Disclaimer