MIS Pedicle Screw Market Size, Share and Trends Analysis - Global - 2025-2031
Description
Global MIS Pedicle Screw Market Report, 2025 Edition
Executive Summary
The global minimally invasive spinal (MIS) pedicle screw market was valued at over $1.3 billion in 2024. The market is expected to grow at a compound annual growth rate (CAGR) of 6.3 percent to exceed $2 billion by 2031.
This report covers percutaneous cannulated, retractor cannulated, and retractor non-cannulated pedicle screw systems. It quantifies unit sales, average selling prices (ASPs), market values, growth rates, and company shares, and analyzes market drivers, limiters, mergers and acquisitions, and technology trends. Historical data from 2021 to 2024 and forecasts to 2031 are provided.
The use of MIS pedicle screw systems continues to expand as healthcare providers seek surgical methods that minimize tissue disruption and accelerate recovery. These systems are designed for percutaneous or mini-open implantation, allowing surgeons to achieve spinal fixation through smaller incisions while maintaining comparable stability to traditional open techniques.
The MIS pedicle screw market benefits from increasing surgeon adoption of minimally invasive spinal fusion procedures, growing patient preference for less invasive treatments, and the ongoing shift toward shorter hospital stays and outpatient care models.
Market Overview
Pedicle screws are essential fixation devices used in spinal fusion procedures to stabilize vertebrae and support bone healing. In the minimally invasive segment, these devices are placed through smaller incisions using percutaneous or tubular retractor systems, reducing muscle dissection and blood loss.
MIS pedicle screw systems can be cannulated—allowing for guidewire-assisted placement—or non-cannulated, designed for specialized retractor systems. Retractor cannulated systems are commonly used in procedures requiring clear visualization of the surgical site, while percutaneous systems enable smaller incisions and shorter recovery times.
Minimally invasive techniques continue to gain traction because they offer clinical and economic advantages compared to open fusion. Hospitals and surgeons value the ability to treat patients effectively while minimizing complications and reducing the length of hospital stay. Patients benefit from faster recovery, reduced pain, and lower postoperative infection risks.
Globally, adoption is driven by the dual pressures of an aging population and patient demand for lower-impact surgical options. Health systems are increasingly aligning reimbursement models with these approaches due to their ability to reduce inpatient resource utilization. As training availability improves and new technologies simplify placement, MIS pedicle screws are becoming a standard component of advanced spinal fusion systems.
Market Drivers
Deformity Correction
While most MIS pedicle screw systems are not traditionally used for complex spinal deformity cases, innovations have broadened their clinical applications. The release of systems such as VIPER® 3D Correction by DePuy Synthes introduced enhanced alignment capabilities, expanding indications into deformity correction.
As more advanced correction systems enter the market, surgeon confidence in performing complex pathologies through MIS techniques is growing. This expansion of procedural indications is expected to drive sustained growth for the overall MIS pedicle screw segment.
360° MIS Fusion
The market benefits from the ongoing adoption of 360° fusion techniques, which allow full circumferential fusion using minimally invasive approaches. For instance, a lateral lumbar interbody fusion (LLIF) system may be used to insert an interbody cage, while pedicle screw fixation is performed percutaneously.
The ability to integrate pedicle screw systems into comprehensive MIS fusion procedures reinforces their importance within the spinal fusion ecosystem. As surgeons increasingly perform multistage fusions using all-MIS approaches, the demand for compatible pedicle screw systems continues to grow.
Minimally Invasive Surgery Preference
Patients and surgeons alike are increasingly choosing minimally invasive procedures over open fusion surgeries. MIS techniques reduce tissue trauma, decrease blood loss, and shorten operating and recovery times. Hospitals also benefit from shorter patient stays, which improves resource utilization and allows operating rooms to accommodate more procedures.
Clinical outcomes for MIS pedicle screw placement have been largely positive, reinforcing surgeon confidence. These advantages—combined with growing patient awareness and strong outcomes data—will continue to support market growth over the forecast period.
Market Limiters
Surgical Complexity
A key challenge in the MIS pedicle screw market is the technical complexity of these procedures. Retractor-based systems require precise alignment and advanced intraoperative imaging. The steep learning curve discourages some surgeons, particularly those trained exclusively in open techniques, from adopting MIS methods.
Training programs are expanding, but adoption is still limited in some regions by insufficient access to specialized education. The time and skill investment required to achieve proficiency remains one of the main barriers to widespread adoption.
Motion Preservation Technologies
Because MIS pedicle screws fall within the total spinal fusion market, growth is affected by motion preservation technologies, such as facet arthroplasty and nucleus replacement. These devices provide alternatives to fusion and allow preservation of motion in treated spinal segments.
As the number of motion-preserving systems increases, particularly in the lumbar spine, overall spinal fusion growth is expected to moderate. While MIS pedicle screw systems may gain share within fusion procedures, total fusion volumes could be constrained by these emerging technologies.
Import Prices and Reimbursement Pressure
Pricing challenges are more pronounced in emerging markets, where exchange rates and lower purchasing power limit adoption. The strength of the U.S. dollar has made premium imported technologies less accessible in several regions.
At the same time, reimbursement frameworks in many countries do not account for the higher cost of MIS instrumentation compared with traditional systems. Manufacturers have had to lower prices or introduce leasing models to remain competitive, putting downward pressure on average selling prices.
Market Coverage and Data Scope
Quantitative Coverage
Market size, market shares, market forecasts, growth rates, units sold, and average selling prices.
Qualitative Coverage
Market growth trends, limiters, competitive analysis and SWOT for top competitors, mergers and acquisitions, company profiles, product portfolios, FDA approvals and recalls, disruptive technologies, and procedure trends.
Time Frame
Historical data: 2021–2024
Base year: 2024
Forecast period: 2025–2031
Data Sources
Primary interviews with spine surgeons, hospital procurement leaders, and industry executives; regulatory and government data; import and export databases; and the iData Research internal MedTech database.
Markets Covered and Segmentation
Global MIS Pedicle Screw Market – Further Segmented Into:
Device Type:
Percutaneous Cannulated
Retractor Cannulated
Retractor Non-Cannulated
Competitive Analysis
Medtronic was the leading competitor in the global MIS pedicle screw market in 2024. The company’s dominance is attributed to its Minimal Access Spine Technologies (MAST) portfolio, which includes advanced percutaneous systems and navigation-compatible solutions. Medtronic led in North America, Western Europe, and the Rest of the World, supported by extensive distribution networks and strong surgeon training programs.
Globus Medical/NuVasive held the second-largest share in 2024. Following their 2023 merger, the combined company expanded its influence through an extensive MIS product lineup and procedural integration across its platforms. Globus/NuVasive maintained the second-highest share in North America and the Rest of the World and continues to strengthen its position through ongoing product innovation and training support.
Stryker ranked third globally in 2024. The company’s share was driven primarily by sales in North America and Western Europe, where its systems are widely used for percutaneous and retractor-based spinal fusion. Stryker’s acquisition strategy and focus on next-generation fixation systems have positioned it well for long-term growth.
Other participants, such as DePuy Synthes, Zimmer Biomet, and SeaSpine, remain active in regional markets or specific subsegments, often emphasizing integration with interbody devices and navigation technologies. Competition in this market is expected to intensify as companies introduce hybrid fixation systems and enhance compatibility with robotic platforms.
Technology and Practice Trends
Integration with surgical navigation and robotic systems is becoming standard, allowing more precise screw placement and reducing radiation exposure.
Expandable screws and modular systems are emerging to provide customizable fixation and simplified revision capabilities.
3D-printed and porous titanium implants are being adopted to promote osseointegration and long-term stability.
Single-position surgery techniques that allow both interbody and pedicle fixation without repositioning the patient are growing in popularity, reducing operating time.
Education and simulation-based training initiatives by manufacturers are improving procedural efficiency and driving adoption among younger surgeons.
Smaller, low-profile screw designs are being developed to minimize muscle irritation and facilitate outpatient spinal fusion procedures.
Geography
This report provides global coverage across North America, Europe, Asia-Pacific, Latin America, the Middle East, and Africa.
Why This Report
Where are the largest and fastest-growing opportunities in the MIS pedicle screw market?
How does adoption vary between percutaneous, retractor cannulated, and non-cannulated systems?
Which procedural and regional trends will drive growth through 2031?
How will integration with navigation and robotics influence system design and pricing?
What are the primary challenges associated with surgeon training and reimbursement?
Which competitors hold the strongest portfolios, and what recent mergers are shaping market dynamics?
How can suppliers align product innovation, pricing, and education to capture emerging demand in MIS fusion?
The Global MIS Pedicle Screw Market Report from iData Research answers these questions with device-level data, company share analysis, and long-term forecasts. Use it to identify growth opportunities, refine product strategies, and support competitive positioning across global spine markets.
About iData Research
iData Research is a premium market intelligence firm headquartered in Canada with offices across North America and Europe.
Over the last 20 years, the company has specialized in device-level sizing, procedure models, pricing trends, and competitive share across MedTech.
Since 2005, iData has supported global OEMs, mid-market innovators, and investors with triangulated data based on units and ASPs, with country-level forecasts and analyst access across Europe, North America, Latin America, the Middle East, Africa, and APAC.
Reports are available with flexible licensing to fit commercial, strategy, and investment workflows
Executive Summary
The global minimally invasive spinal (MIS) pedicle screw market was valued at over $1.3 billion in 2024. The market is expected to grow at a compound annual growth rate (CAGR) of 6.3 percent to exceed $2 billion by 2031.
This report covers percutaneous cannulated, retractor cannulated, and retractor non-cannulated pedicle screw systems. It quantifies unit sales, average selling prices (ASPs), market values, growth rates, and company shares, and analyzes market drivers, limiters, mergers and acquisitions, and technology trends. Historical data from 2021 to 2024 and forecasts to 2031 are provided.
The use of MIS pedicle screw systems continues to expand as healthcare providers seek surgical methods that minimize tissue disruption and accelerate recovery. These systems are designed for percutaneous or mini-open implantation, allowing surgeons to achieve spinal fixation through smaller incisions while maintaining comparable stability to traditional open techniques.
The MIS pedicle screw market benefits from increasing surgeon adoption of minimally invasive spinal fusion procedures, growing patient preference for less invasive treatments, and the ongoing shift toward shorter hospital stays and outpatient care models.
Market Overview
Pedicle screws are essential fixation devices used in spinal fusion procedures to stabilize vertebrae and support bone healing. In the minimally invasive segment, these devices are placed through smaller incisions using percutaneous or tubular retractor systems, reducing muscle dissection and blood loss.
MIS pedicle screw systems can be cannulated—allowing for guidewire-assisted placement—or non-cannulated, designed for specialized retractor systems. Retractor cannulated systems are commonly used in procedures requiring clear visualization of the surgical site, while percutaneous systems enable smaller incisions and shorter recovery times.
Minimally invasive techniques continue to gain traction because they offer clinical and economic advantages compared to open fusion. Hospitals and surgeons value the ability to treat patients effectively while minimizing complications and reducing the length of hospital stay. Patients benefit from faster recovery, reduced pain, and lower postoperative infection risks.
Globally, adoption is driven by the dual pressures of an aging population and patient demand for lower-impact surgical options. Health systems are increasingly aligning reimbursement models with these approaches due to their ability to reduce inpatient resource utilization. As training availability improves and new technologies simplify placement, MIS pedicle screws are becoming a standard component of advanced spinal fusion systems.
Market Drivers
Deformity Correction
While most MIS pedicle screw systems are not traditionally used for complex spinal deformity cases, innovations have broadened their clinical applications. The release of systems such as VIPER® 3D Correction by DePuy Synthes introduced enhanced alignment capabilities, expanding indications into deformity correction.
As more advanced correction systems enter the market, surgeon confidence in performing complex pathologies through MIS techniques is growing. This expansion of procedural indications is expected to drive sustained growth for the overall MIS pedicle screw segment.
360° MIS Fusion
The market benefits from the ongoing adoption of 360° fusion techniques, which allow full circumferential fusion using minimally invasive approaches. For instance, a lateral lumbar interbody fusion (LLIF) system may be used to insert an interbody cage, while pedicle screw fixation is performed percutaneously.
The ability to integrate pedicle screw systems into comprehensive MIS fusion procedures reinforces their importance within the spinal fusion ecosystem. As surgeons increasingly perform multistage fusions using all-MIS approaches, the demand for compatible pedicle screw systems continues to grow.
Minimally Invasive Surgery Preference
Patients and surgeons alike are increasingly choosing minimally invasive procedures over open fusion surgeries. MIS techniques reduce tissue trauma, decrease blood loss, and shorten operating and recovery times. Hospitals also benefit from shorter patient stays, which improves resource utilization and allows operating rooms to accommodate more procedures.
Clinical outcomes for MIS pedicle screw placement have been largely positive, reinforcing surgeon confidence. These advantages—combined with growing patient awareness and strong outcomes data—will continue to support market growth over the forecast period.
Market Limiters
Surgical Complexity
A key challenge in the MIS pedicle screw market is the technical complexity of these procedures. Retractor-based systems require precise alignment and advanced intraoperative imaging. The steep learning curve discourages some surgeons, particularly those trained exclusively in open techniques, from adopting MIS methods.
Training programs are expanding, but adoption is still limited in some regions by insufficient access to specialized education. The time and skill investment required to achieve proficiency remains one of the main barriers to widespread adoption.
Motion Preservation Technologies
Because MIS pedicle screws fall within the total spinal fusion market, growth is affected by motion preservation technologies, such as facet arthroplasty and nucleus replacement. These devices provide alternatives to fusion and allow preservation of motion in treated spinal segments.
As the number of motion-preserving systems increases, particularly in the lumbar spine, overall spinal fusion growth is expected to moderate. While MIS pedicle screw systems may gain share within fusion procedures, total fusion volumes could be constrained by these emerging technologies.
Import Prices and Reimbursement Pressure
Pricing challenges are more pronounced in emerging markets, where exchange rates and lower purchasing power limit adoption. The strength of the U.S. dollar has made premium imported technologies less accessible in several regions.
At the same time, reimbursement frameworks in many countries do not account for the higher cost of MIS instrumentation compared with traditional systems. Manufacturers have had to lower prices or introduce leasing models to remain competitive, putting downward pressure on average selling prices.
Market Coverage and Data Scope
Quantitative Coverage
Market size, market shares, market forecasts, growth rates, units sold, and average selling prices.
Qualitative Coverage
Market growth trends, limiters, competitive analysis and SWOT for top competitors, mergers and acquisitions, company profiles, product portfolios, FDA approvals and recalls, disruptive technologies, and procedure trends.
Time Frame
Historical data: 2021–2024
Base year: 2024
Forecast period: 2025–2031
Data Sources
Primary interviews with spine surgeons, hospital procurement leaders, and industry executives; regulatory and government data; import and export databases; and the iData Research internal MedTech database.
Markets Covered and Segmentation
Global MIS Pedicle Screw Market – Further Segmented Into:
Device Type:
Percutaneous Cannulated
Retractor Cannulated
Retractor Non-Cannulated
Competitive Analysis
Medtronic was the leading competitor in the global MIS pedicle screw market in 2024. The company’s dominance is attributed to its Minimal Access Spine Technologies (MAST) portfolio, which includes advanced percutaneous systems and navigation-compatible solutions. Medtronic led in North America, Western Europe, and the Rest of the World, supported by extensive distribution networks and strong surgeon training programs.
Globus Medical/NuVasive held the second-largest share in 2024. Following their 2023 merger, the combined company expanded its influence through an extensive MIS product lineup and procedural integration across its platforms. Globus/NuVasive maintained the second-highest share in North America and the Rest of the World and continues to strengthen its position through ongoing product innovation and training support.
Stryker ranked third globally in 2024. The company’s share was driven primarily by sales in North America and Western Europe, where its systems are widely used for percutaneous and retractor-based spinal fusion. Stryker’s acquisition strategy and focus on next-generation fixation systems have positioned it well for long-term growth.
Other participants, such as DePuy Synthes, Zimmer Biomet, and SeaSpine, remain active in regional markets or specific subsegments, often emphasizing integration with interbody devices and navigation technologies. Competition in this market is expected to intensify as companies introduce hybrid fixation systems and enhance compatibility with robotic platforms.
Technology and Practice Trends
Integration with surgical navigation and robotic systems is becoming standard, allowing more precise screw placement and reducing radiation exposure.
Expandable screws and modular systems are emerging to provide customizable fixation and simplified revision capabilities.
3D-printed and porous titanium implants are being adopted to promote osseointegration and long-term stability.
Single-position surgery techniques that allow both interbody and pedicle fixation without repositioning the patient are growing in popularity, reducing operating time.
Education and simulation-based training initiatives by manufacturers are improving procedural efficiency and driving adoption among younger surgeons.
Smaller, low-profile screw designs are being developed to minimize muscle irritation and facilitate outpatient spinal fusion procedures.
Geography
This report provides global coverage across North America, Europe, Asia-Pacific, Latin America, the Middle East, and Africa.
Why This Report
Where are the largest and fastest-growing opportunities in the MIS pedicle screw market?
How does adoption vary between percutaneous, retractor cannulated, and non-cannulated systems?
Which procedural and regional trends will drive growth through 2031?
How will integration with navigation and robotics influence system design and pricing?
What are the primary challenges associated with surgeon training and reimbursement?
Which competitors hold the strongest portfolios, and what recent mergers are shaping market dynamics?
How can suppliers align product innovation, pricing, and education to capture emerging demand in MIS fusion?
The Global MIS Pedicle Screw Market Report from iData Research answers these questions with device-level data, company share analysis, and long-term forecasts. Use it to identify growth opportunities, refine product strategies, and support competitive positioning across global spine markets.
About iData Research
iData Research is a premium market intelligence firm headquartered in Canada with offices across North America and Europe.
Over the last 20 years, the company has specialized in device-level sizing, procedure models, pricing trends, and competitive share across MedTech.
Since 2005, iData has supported global OEMs, mid-market innovators, and investors with triangulated data based on units and ASPs, with country-level forecasts and analyst access across Europe, North America, Latin America, the Middle East, Africa, and APAC.
Reports are available with flexible licensing to fit commercial, strategy, and investment workflows
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