Peptide Therapeutics Market: Industry Trends and Global Forecasts, Till 2040 - Distribution by Type of Peptide, Route of Administration, Key Therapeutic Area and Geographical Regions

Peptide Therapeutics Market: Overview

As per Roots Analysis, the peptide therapeutics market is estimated to grow from USD 84.2 billion in the current year to USD 162.4 billion by 2035, at a CAGR of 6.8% during the forecast period, till 2035.

Peptide Therapeutics Market

The market sizing and opportunity analysis has been segmented across the following parameters:

Route of Administration

• Intravenous
• Oral
• Subcutaneous
• Topical
• Other

Key Therapeutic Area

• Metabolic Diseases
• Oncological Diseases
• Endocrine Diseases
• Digestive and Gastrointestinal Diseases
• Others

Geographical Regions

• North America
• Europe
• Asia-Pacific
• Rest of the World

Peptide Therapeutics Market: Growth and Trends

Peptide therapeutics are a class of medications developed with polypeptides to cater to various illnesses. Generally, naturally occurring peptides can serve as growth factors, hormones, neurotransmitters, anti-infectives, and ligands for ion channels. Such peptides have been utilized in creating peptide-based therapies that are commonly employed in treating metabolic diseases, cancer, and hormone-related treatments. It is noteworthy that more than 100 peptide-based therapies have been authorized by the FDA in various nations. Examples of recognized peptide therapeutics include Tirzepatide (Mounjaro®), Lutetium Lu-177 vipivotide tetraxetan (Pluvicto®), and Lupkynis™. Driven by the rising prevalence of chronic conditions, such as diabetes, osteoarthritis, obesity, autoimmune disorders, rheumatoid arthritis, and cancer, an increased demand for biologics in disease treatment has been observed in recent years.

Biologics such as recombinant proteins and peptides present multiple benefits, including heightened target specificity, good safety profiles, low toxicity, and reduced likelihood of off-target effects. Notably, many pharmaceutical firms are focusing on the advancement of innovative drug conjugates, including peptide drug conjugates, peptide therapeutics, and cell-penetrating peptides to address a wide array of diseases. Moreover, recent progress in this area has resulted in the authorization and clinical application of peptide medications for disorders such as type 2 diabetes, obesity, and several cancers. We are led to believe that the market is likely to achieve notable growth in the foreseeable future.

Peptide Therapeutics Market: Key Insights

The report delves into the current state of the peptide therapeutics market and identifies potential growth opportunities within industry. Some key findings from the report include:

• With 25 approved drugs and over 280 candidates under development, peptide therapeutics currently represent one of the fastest growing drug classes, capable of treating a diverse range of diseases.
• The pipeline features a variety of peptides being evaluated for delivery via different routes, and mostly intended for treating metabolic and oncological disorders
• In lieu of the growing competition from several viable candidate therapies, innovators are putting in significant efforts to ensure that their proprietary offerings are both clinically and commercially differentiated.
• Over 1,200 peptide focused clinical trials have been registered across the world; presently, most of these studies are evaluating product candidates intended for the treatment of metabolic diseases.
• The growing interest in this field is also evident in the increase in recent partnership activity; majority of the deals were focused on technology and / or product licensing.
• Foreseeing promising returns, many public and private sector investors have invested over USD 7 billion, across more than 200 instances.
• In order to tap into the lucrative opportunity in this rapidly growing market, several big pharma players have undertaken initiatives, ranging from proprietary product development to strategic investments, in this direction.
• With a promising development pipeline and encouraging clinical outcomes, the peptide therapeutics market is anticipated to grow at an annualized rate of 6.8%, over the next decade.

Peptide Therapeutics Market: Key Segments

Medium Size Peptides in the Peptide Therapeutics Industry Holds the Largest Share

In the current year, medium sized peptides capture the majority (close to 65% of the market) share. This is probably because medium-sized peptides (ranging from 10 to 40 amino acids) effectively strike a balance between larger proteins and smaller molecules. It is worth highlighting that, small peptides will grow at a CAGR of more than 20% during the forecast period, owing to the increasing usage in manufacturing target specific drugs.

Subcutaneous Route of Administration to Dominate the Peptide Therapeutics Market

The overall market is segmented into intravenous, oral, subcutaneous, topical, and others. In the current year, subcutaneous route of administration accounts for more than 65% of the overall market. The subcutaneous route can avoid the gastrointestinal tract and liver (first-pass metabolism), resulting in greater therapeutic effectiveness. Owing to the ongoing demand for non-invasive or target specific routes of administration, the topical route of administration is likely to grow at a CAGR of ~30% during the forecast period.

Metabolic Diseases Segment to Hold the Highest Peptide Therapeutics Market

Currently, the metabolic diseases segment is likely to capture more than 60% of the overall market share. This is attributed to the increasing need for peptide-based therapies aimed at addressing metabolic conditions like diabetes and obesity. Notably, the peptide therapeutics market for gastrointestinal diseases will expand with a higher CAGR of 25% during the forecast period.

North America to Propel in the Peptide Therapeutics Industry in the Coming Years

This segment highlights the distribution of market across various geographies, such as North America, Europe and Asia-Pacific. According to our projections, North America accounts for the majority of the market share in the current year, and this trend is unlikely to change in the future. According to the report of Centers for Disease Control and Prevention, nearly 129 million people in the United States have at least one or more chronic disease such as diabetes, obesity, heart disease, and hypertension. This is leading to growing demand for peptide therapeutics in this region. It is worth highlighting that the market in Asia-Pacific is likely to grow at a relatively higher CAGR during the forecast period.

Example Players in the Peptide Therapeutics Market

• Apellis Pharmaceuticals
• BioLineRx
• Eli Lilly
• FirstString Research
• Novo Nordisk
• Palatin Technologies
• RegeneRx Biopharmaceuticals
• Stealth BioTherapeutics
• Takeda
• Zealand Pharma

Peptide Therapeutics Market: Research Coverage

• Market Sizing and Opportunity Analysis: The report features an in-depth analysis of the peptide therapeutics market, focusing on key market segments, including [A] type of peptide, [B] route of administration, [C] key therapeutic area, [D] geographical regions.
• Market Landscape: provides a detailed assessment of over 300 peptide-based therapies that are currently approved or are in different stages of development, based on several relevant parameters, such as [A] phase of development, [B] type of peptide, [C] route of administration, [D] key therapeutic areas, [E] year of establishment, [F] company size, and [G] location of headquarters.
• Company Profiles: In-depth profiles of prominent players engaged in this domain, focusing on [A] year of establishment, [B] location of headquarters, [C] peptide details [D] recent developments and [E] an informed future outlook.
• Big Pharma Initiatives: An analysis of top big biopharma players engaged in the field of therapeutic peptides, based on several parameters, including [A] number of amino acids, [B] route of administration and [C] therapeutic area.
• Partnerships and Collaborations An insightful analysis of the partnerships and collaborations inked between stakeholders engaged in the peptide therapeutics market based on various relevant parameters, including [A] year of partnership, [B] type of partnership, [C] type of partner and [D] most active players.
• Funding and Investment Analysis: A comprehensive examination of various funding and investments raised by developers of peptide therapeutics, based on relevant parameters, including [A] such as year of funding, [B] amount invested [C] type of funding, [D] regional distribution, and [E] most active players.
• Clinical Trial Analysis: A detailed review of completed, ongoing, and planned clinical studies of various therapeutic peptides, based on relevant parameters, such as [A] trail registration year, [B] phase of development, [C] current trial status and [D] enrolled patient population.
• Case Study 1: A case study focused on the role of service providers that operate within the peptide therapeutics market and captures information on the various CROs, CMOs and custom peptide manufacturers that are actively involved in this segment of the peptide therapeutics market.
• Case Study 2: A case study presenting the key characteristics of novel peptides drugs, along with information on the applications, advantages and key challenges involved in their development processes.

Key Questions Answered in this Report

• How many companies are currently engaged in this market?
• Which are the leading companies in this market?
• What is the current global capacity of developers?
• What factors are likely to influence the evolution of this market?
• What is the current and future market size?
• What is the CAGR of this market?
• How is the current and future market opportunity likely to be distributed across key market segments?

Reasons to Buy this Report

• The report provides a comprehensive market analysis, offering detailed revenue projections of the overall market and its specific sub-segments. This information is valuable to both established market leaders and emerging entrants.
• Stakeholders can leverage the report to gain a deeper understanding of the competitive dynamics within the market. By analyzing the competitive landscape, businesses can make informed decisions to optimize their market positioning and develop effective go-to-market strategies.
• The report offers stakeholders a comprehensive overview of the market, including key drivers, barriers, opportunities, and challenges. This information empowers stakeholders to stay abreast of market trends and make data-driven decisions to capitalize on growth prospects.

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