Protein A Resin Market Size, Share, Trends, Industry Analysis Report: By Type (Recombinant Protein A and Natural Protein A), By Product, By Application, By End User, and By Region – Market Forecast, 2025–2034

The protein a resin market size is expected to reach USD 2,832.54 million by 2034, according to a new study by Polaris Market Research. The report “Protein A Resin Market Size, Share, Trends, Industry Analysis Report: By Type (Recombinant Protein A and Natural Protein A), By Product, By Application, By End User, and By Region – Market Forecast, 2025–2034” gives a detailed insight into current market dynamics and provides analysis on future market growth.

Protein A resin is a chromatography material used to selectively purify antibodies, especially monoclonal antibodies, by binding to the Fc region of immunoglobulin G (IgG).

Rising demand for monoclonal antibodies (mAbs) is driving the protein A resin market growth. Monoclonal antibodies are lab-made proteins that help the immune system identify and attack harmful cells, such as cancer cells or viruses. They have become one of the most successful types of biologic drugs, especially in treating cancer, autoimmune diseases, and chronic illnesses. As these drugs are so effective and in high demand, pharmaceutical companies need reliable ways to purify them during manufacturing. Protein A resin is specially designed to bind with antibodies, making it a key tool in their purification. As more antibody therapies are developed, the need for Protein A resin continues to grow rapidly.

Chromatography is a method used to separate different components of a mixture, and Protein A resin is a key material in this process for purifying antibodies. Over the years, manufacturers have improved these resins to be more stable, faster, and longer-lasting. For example, newer protein A resins can withstand harsher cleaning chemicals, offer higher binding capacities, and allow quicker processing times. These advancements reduce manufacturing costs and increase efficiency. As companies look for ways to make drug production faster and cheaper, improved chromatography resins are in high demand, making technological progress a major driver of the market.

Protein A Resin Market Report Highlights

In 2024, based on type, the recombinant protein A segment dominated the protein A resin market, as these resins are engineered through recombinant DNA technology, allowing for the production of protein A ligands with specific characteristics optimized for protein purification.

The agarose-based protein A segment, by product, is expected to witness significant growth during the forecast period due to its extensive utilization in various applications across the biopharmaceutical and biotechnology industries.

In 2024, North America dominated the market. North American pharmaceutical companies, research institutions, and government organizations are channeling substantial investments in research and development activities, which propels the market expansion in the region.

Asia Pacific is expected to record the highest CAGR during the forecast period due to increasing healthcare investments, supportive government policies, and rising demand for biologic drugs.

A few global key market players are Abcam PLC; Agilent Technologies; Bio-Rad Laboratories, Inc.; Danaher Corporation; EMD Millipore; Expedeon Ltd; GenScript Biotech Corp.; Merck KGaA; Novasep Holdings SAS; PerkinElmer, Inc.; Purolite Life Sciences; Repligen Corp.; Thermo Fisher Scientific Inc.; and Tosoh Bioscience.

Polaris Market Research has segmented the protein a resin market report on the basis of type, product, application, end use, and region:

By Type Outlook (Revenue USD Million, 2020–2034)

Recombinant Protein A

Natural Protein A

By Product Outlook (Revenue USD Million, 2020–2034)

Organic Polymer-Based Protein A

Agarose-Based Protein A

Glass/Silica-Based Protein A

By Application Outlook (Revenue USD Million, 2020–2034)

Immunoprecipitation

Antibody Purification

By End User Outlook (Revenue USD Million, 2020–2034)

Academic Research Institutes

Pharmaceutical Companies

Others

By Regional Outlook (Revenue USD Million, 2020–2034)

North America

US

Canada

Europe

Germany

France

UK

Italy

Spain

Netherlands

Russia

Rest of Europe

Asia Pacific

China

Japan

India

Malaysia

South Korea

Indonesia

Australia

Rest of Asia Pacific

Middle East & Africa

Saudi Arabia

UAE

Israel

South Africa

Rest of Middle East & Africa

Latin America

Mexico

Brazil

Argentina

Rest of Latin America