Endoscopic Submucosal Dissection Market Size, Share, Trends, Industry Analysis Report: By Product (Gastroscopes and Colonoscopes, Knives, Injection Agents, Tissue Retractors, Graspers/Clips, and Others), Indication, End Use, and Region (North America, Eur

The global endoscopic submucosal dissection market size is expected to reach USD 618.18 million by 2034, according to a new study by Polaris Market Research. The report “Endoscopic Submucosal Dissection Market Size, Share, Trends, Industry Analysis Report: By Product (Gastroscopes and Colonoscopes, Knives, Injection Agents, Tissue Retractors, Graspers/Clips, and Others), Indication, End Use, and Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) – Market Forecast, 2025–2034” gives a detailed insight into current market dynamics and provides analysis on future market growth.

Endoscopic submucosal dissection (ESD) is a highly specialized endoscopic technique that enables en-bloc resection of gastrointestinal lesions, reducing the need for more invasive surgical interventions. The endoscopic submucosal dissection market is experiencing significant growth due to the rising prevalence of early-stage gastrointestinal (GI) cancers and the increasing demand for minimally invasive procedures. The market growth is also driven by advancements in electrosurgical knives, endoscopic imaging systems, and AI-assisted diagnostics, improving procedural accuracy and clinical outcomes. Market demand is further fueled by the shift toward organ-preserving therapies, particularly in cases of esophageal, gastric, and colorectal cancers.

The endoscopic submucosal dissection market landscape is being shaped by trends such as the integration of robot-assisted endoscopic procedures, enhanced hemostatic techniques, and real-time AI-driven lesion detection systems. Additionally, increasing investments in physician training programs and skill development initiatives are accelerating the adoption of ESD, creating a substantial market opportunity for medical device manufacturers. The market dynamics are also influenced by regulatory approvals for next-generation ESD devices, supporting widespread clinical adoption.

Healthcare institutions are prioritizing cost-effective and efficient treatment modalities, driving preference for advanced endoscopic resection techniques over traditional surgical approaches. Moreover, the rising awareness of early cancer detection and improved access to advanced endoscopic technologies are contributing to the rising demand for ESD. With continuous technological advancements, increasing procedural success rates, and expanding reimbursement frameworks, the adoption of ESD is expected to surge, presenting lucrative endoscopic submucosal dissection market opportunities for stakeholders.

Endoscopic Submucosal Dissection Market Report Highlights

In terms of product, the knives segment accounted for the largest market share in 2024 due to their critical role in precise mucosal dissection, enabling improved en bloc resection of gastrointestinal lesions.

Based on end use, the hospitals segment held the largest market share in 2024 due to the availability of advanced endoscopic infrastructure, specialized medical expertise, and a higher volume of complex ESD procedures.

In 2024, North America accounted for the largest market share due to the increasing adoption of minimally invasive procedures, the rising prevalence of gastrointestinal cancers, and well-established reimbursement policies.

The Asia Pacific endoscopic submucosal dissection market is expected to witness the highest CAGR during the forecast period due to rapid advancements in endoscopic technology, growing awareness of early cancer detection, and increasing healthcare investments.

Some of the global key market players are Boston Scientific Corporation, CONMED Corporation, Cook Group, Creo Medical, FUJIFILM Holdings Corporation, Karl Storz GmbH & Co. KG, Medtronic, Micro-Tech Endoscopy, Olympus Corporation, PENTAX Medical (Hoya Corporation), and STERIS plc.

Polaris Market Research has segmented the endoscopic submucosal dissection market report on the basis of product, indication, end use, and region:

By Product Outlook (Revenue, USD Million, 2020–2034)

Gastroscopes and Colonoscopes

Knives

Injection Agents

Tissue Retractors

Graspers/ Clips

Others

By Indication Outlook (Revenue, USD Million, 2020–2034)

Stomach Cancer

Colon Cancer

Esophageal Cancer

By End Use Outlook (Revenue, USD Million, 2020–2034)

Hospitals

Outpatients Facilities

By Regional Outlook (Revenue, USD Million, 2020–2034)

North America

  • US
  • Canada
Europe
  • Germany
  • France
  • UK
  • Italy
  • Spain
  • Netherlands
  • Russia
  • Rest of Europe
Asia Pacific
  • China
  • Japan
  • India
  • Malaysia
  • South Korea
  • Indonesia
  • Australia
  • Vietnam
  • Rest of Asia Pacific
Middle East & Africa
  • Saudi Arabia
  • UAE
  • Israel
  • South Africa
  • Rest of Middle East & Africa
Latin America
  • Mexico
  • Brazil
  • Argentina
  • Rest of Latin America


1. Introduction
1.1. Report Description
1.1.1. Objectives of the Study
1.1.2. Market Scope
1.1.3. Assumptions
1.2. Stakeholders
2. Executive Summary
2.1. Market Highlights
3. Research Methodology
3.1. Overview
3.1.1. Data Mining
3.2. Data Sources
3.2.1. Primary Sources
3.2.2. Secondary Sources
4. Global Endoscopic Submucosal Dissection Market Insights
4.1. Endoscopic Submucosal Dissection Market – Market Snapshot
4.2. Endoscopic Submucosal Dissection Market Dynamics
4.2.1. Drivers and Opportunities
4.2.1.1. Rising Prevalence of Gastrointestinal Cancers
4.2.1.2. Growing Adoption of Minimally Invasive Procedures
4.2.2. Restraints and Challenges
4.2.2.1. Competition from Alternative Technologies.
4.3. Porter’s Five Forces Analysis
4.3.1. Bargaining Power of Suppliers (Moderate)
4.3.2. Threats of New Entrants: (Low)
4.3.3. Bargaining Power of Buyers (Moderate)
4.3.4. Threat of Substitute (Moderate)
4.3.5. Rivalry among existing firms (High)
4.4. PESTEL Analysis
4.5. Endoscopic Submucosal Dissection Market Application Trends
4.6. Value Chain Analysis
5. Global Endoscopic Submucosal Dissection Market, by Product
5.1. Key Findings
5.2. Introduction
5.2.1. Global Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
5.3. Gastroscopes and Colonoscopes
5.3.1. Global Endoscopic Submucosal Dissection Market, by Gastroscopes and Colonoscopes, by Region, 2021-2034 (USD Million)
5.4. Knives
5.4.1. Global Endoscopic Submucosal Dissection Market, by Knives, by Region, 2021-2034 (USD Million)
5.5. Injection Agents
5.5.1. Global Endoscopic Submucosal Dissection Market, by Injection Agents, by Region, 2021-2034 (USD Million)
5.6. Tissue Retractors
5.6.1. Global Endoscopic Submucosal Dissection Market, by Tissue Retractors, by Region, 2021-2034 (USD Million)
5.7. Graspers/ Clips
5.7.1. Global Endoscopic Submucosal Dissection Market, by Graspers/ Clips, by Region, 2021-2034 (USD Million)
5.8. Others
5.8.1. Global Endoscopic Submucosal Dissection Market, by Others, by Region, 2021-2034 (USD Million)
6. Global Endoscopic Submucosal Dissection Market, by Indication
6.1. Key Findings
6.2. Introduction
6.2.1. Global Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
6.3. Stomach Cancer
6.3.1. Global Endoscopic Submucosal Dissection Market, by Stomach Cancer, by Region, 2021-2034 (USD Million)
6.4. Colon Cancer
6.4.1. Global Endoscopic Submucosal Dissection Market, by Colon Cancer, by Region, 2021-2034 (USD Million)
6.5. Esophageal Cancer
6.5.1. Global Endoscopic Submucosal Dissection Market, by Esophageal Cancer, by Region, 2021-2034 (USD Million)
7. Global Endoscopic Submucosal Dissection Market, by End Use
7.1. Key Findings
7.2. Introduction
7.2.1. Global Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
7.3. Hospitals
7.3.1. Global Endoscopic Submucosal Dissection Market, by Hospitals, by Region, 2021-2034 (USD Million)
7.4. Outpatients facilities
7.4.1. Global Endoscopic Submucosal Dissection Market, by Outpatients facilities, by Region, 2021-2034 (USD Million)
8. Global Endoscopic Submucosal Dissection Market, by Geography
8.1. Key Findings
8.2. Introduction
8.2.1. Endoscopic Submucosal Dissection Market Assessment, By Geography, 2021-2034 (USD Million)
8.3. Endoscopic Submucosal Dissection Market – North America
8.3.1. North America: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.3.2. North America: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.3.3. North America: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.3.4. Endoscopic Submucosal Dissection Market – U.S.
8.3.4.1. U.S.: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.3.4.2. U.S.: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.3.4.3. U.S.: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.3.5. Endoscopic Submucosal Dissection Market – Canada
8.3.5.1. Canada: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.3.5.2. Canada: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.3.5.3. Canada: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.4. Endoscopic Submucosal Dissection Market – Europe
8.4.1. Europe: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.4.2. Europe: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.4.3. Europe: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.4.4. Endoscopic Submucosal Dissection Market – UK
8.4.4.1. UK: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.4.4.2. UK: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.4.4.3. UK: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.4.5. Endoscopic Submucosal Dissection Market – France
8.4.5.1. France: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.4.5.2. France: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.4.5.3. France: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.4.6. Endoscopic Submucosal Dissection Market – Germany
8.4.6.1. Germany: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.4.6.2. Germany: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.4.6.3. Germany: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.4.7. Endoscopic Submucosal Dissection Market – Italy
8.4.7.1. Italy: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.4.7.2. Italy: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.4.7.3. Italy: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.4.8. Endoscopic Submucosal Dissection Market – Spain
8.4.8.1. Spain: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.4.8.2. Spain: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.4.8.3. Spain: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.4.9. Endoscopic Submucosal Dissection Market – Netherlands
8.4.9.1. Netherlands: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.4.9.2. Netherlands: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.4.9.3. Netherlands: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.4.10. Endoscopic Submucosal Dissection Market – Russia
8.4.10.1. Russia: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.4.10.2. Russia: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.4.10.3. Russia: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.4.11. Endoscopic Submucosal Dissection Market – Rest of Europe
8.4.11.1. Rest of Europe: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.4.11.2. Rest of Europe: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.4.11.3. Rest of Europe: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.5. Endoscopic Submucosal Dissection Market – Asia Pacific
8.5.1. Asia Pacific: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.5.2. Asia Pacific: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.5.3. Asia Pacific: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.5.4. Endoscopic Submucosal Dissection Market – China
8.5.4.1. China: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.5.4.2. China: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.5.4.3. China: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.5.5. Endoscopic Submucosal Dissection Market – India
8.5.5.1. India: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.5.5.2. India: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.5.5.3. India: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.5.6. Endoscopic Submucosal Dissection Market – Malaysia
8.5.6.1. Malaysia: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.5.6.2. Malaysia: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.5.6.3. Malaysia: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.5.7. Endoscopic Submucosal Dissection Market – Japan
8.5.7.1. Japan: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.5.7.2. Japan: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.5.7.3. Japan: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.5.8. Endoscopic Submucosal Dissection Market – Indonesia
8.5.8.1. Indonesia: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.5.8.2. Indonesia: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.5.8.3. Indonesia: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.5.9. Endoscopic Submucosal Dissection Market – South Korea
8.5.9.1. South Korea: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.5.9.2. South Korea: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.5.9.3. South Korea: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.5.10. Endoscopic Submucosal Dissection Market – Australia
8.5.10.1. Australia: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.5.10.2. Australia: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.5.10.3. Australia: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.5.11. Endoscopic Submucosal Dissection Market – Rest of Asia Pacific
8.5.11.1. Rest of Asia Pacific: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.5.11.2. Rest of Asia Pacific: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.5.11.3. Rest of Asia Pacific: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.6. Endoscopic Submucosal Dissection Market – Middle East & Africa
8.6.1. Middle East & Africa: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.6.2. Middle East & Africa: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.6.3. Middle East & Africa: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.6.4. Endoscopic Submucosal Dissection Market – Saudi Arabia
8.6.4.1. Saudi Arabia: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.6.4.2. Saudi Arabia: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.6.4.3. Saudi Arabia: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.6.5. Endoscopic Submucosal Dissection Market – UAE
8.6.5.1. UAE: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.6.5.2. UAE: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.6.5.3. UAE: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.6.6. Endoscopic Submucosal Dissection Market – Israel
8.6.6.1. Israel: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.6.6.2. Israel: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.6.6.3. Israel: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.6.7. Endoscopic Submucosal Dissection Market – South Africa
8.6.7.1. South Africa: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.6.7.2. South Africa: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.6.7.3. South Africa: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.6.8. Endoscopic Submucosal Dissection Market – Rest of Middle East & Africa
8.6.8.1. Rest of Middle East & Africa: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.6.8.2. Rest of Middle East & Africa: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.6.8.3. Rest of Middle East & Africa: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.7. Endoscopic Submucosal Dissection Market – Latin America
8.7.1. Latin America: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.7.2. Latin America: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.7.3. Latin America: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.7.4. Endoscopic Submucosal Dissection Market – Mexico
8.7.4.1. Mexico: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.7.4.2. Mexico: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.7.4.3. Mexico: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.7.5. Endoscopic Submucosal Dissection Market – Brazil
8.7.5.1. Brazil: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.7.5.2. Brazil: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.7.5.3. Brazil: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.7.6. Endoscopic Submucosal Dissection Market – Argentina
8.7.6.1. Argentina: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.7.6.2. Argentina: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.7.6.3. Argentina: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
8.7.7. Endoscopic Submucosal Dissection Market – Rest of Latin America
8.7.7.1. Rest of Latin America: Endoscopic Submucosal Dissection Market, by Product, 2021-2034 (USD Million)
8.7.7.2. Rest of Latin America: Endoscopic Submucosal Dissection Market, by Indication, 2021-2034 (USD Million)
8.7.7.3. Rest of Latin America: Endoscopic Submucosal Dissection Market, by End Use, 2021-2034 (USD Million)
9. Competitive Landscape
9.1. Expansion and Acquisition Analysis
9.1.1. Expansion
9.1.2. Acquisitions
9.2. Partnerships/Collaborations/Agreements/Exhibitions
10. Company Profiles
10.1. Boston Scientific Corporation
10.1.1. Company Overview
10.1.2. Financial Performance
10.1.3. Product Benchmarking
10.1.4. Recent Development
10.2. CONMED Corporation
10.2.1. Company Overview
10.2.2. Financial Performance
10.2.3. Product Benchmarking
10.2.4. Recent Development
10.3. Cook Group
10.3.1. Company Overview
10.3.2. Financial Performance
10.3.3. Product Benchmarking
10.3.4. Recent Development
10.4. Cook Group
10.4.1. Company Overview
10.4.2. Financial Performance
10.4.3. Product Benchmarking
10.4.4. Recent Development
10.5. FUJIFILM Holdings Corporation
10.5.1. Company Overview
10.5.2. Financial Performance
10.5.3. Product Benchmarking
10.5.4. Recent Development
10.6. Karl Storz GmbH & Co. KG
10.6.1. Company Overview
10.6.2. Financial Performance
10.6.3. Product Benchmarking
10.6.4. Recent Development
10.7. Medtronic
10.7.1. Company Overview
10.7.2. Financial Performance
10.7.3. Product Benchmarking
10.7.4. Recent Development
10.8. Micro-Tech Endoscopy
10.8.1. Company Overview
10.8.2. Financial Performance
10.8.3. Product Benchmarking
10.8.4. Recent Development
10.9. Olympus Corporation
10.9.1. Company Overview
10.9.2. Financial Performance
10.9.3. Product Benchmarking
10.9.4. Recent Development
10.10. PENTAX Medical (Hoya Corporation)
10.10.1. Company Overview
10.10.2. Financial Performance
10.10.3. Product Benchmarking
10.10.4. Recent Development
10.11. STERIS plc.
10.11.1. Company Overview
10.11.2. Financial Performance
10.11.3. Product Benchmarking
10.11.4. Recent Development

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