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U.S. Antifungal Drugs Market Size, Share, Trend, Industry Analysis Report By Drug Class (Azoles, Echinocandins, Polyenes, Allylamines, Others), By Indication, By Dosage Form, By Distribution Channel – Market Forecast, 2025–2034

Published Jul 01, 2025
Length 128 Pages
SKU # PLRS20324540

Description

The U.S. antifungal drugs market size is expected to reach USD 7.96 billion by 2034, according to a new study by Polaris Market Research. The report “U.S. Antifungal Drugs Market Size, Share, Trend, Industry Analysis Report By Drug Class (Azoles, Echinocandins, Polyenes, Allylamines, Others), By Indication, By Dosage Form, By Distribution Channel – Market Forecast, 2025–2034” gives a detailed insight into current market dynamics and provides analysis on future market growth.

The U.S. antifungal drugs market focuses on the development, distribution, and utilization of medications designed to treat fungal infections ranging from superficial to invasive forms. Demand is largely driven by the growing prevalence of fungal diseases in immunologically vulnerable populations, including patients undergoing cancer therapy, organ transplantation, or long-term immunosuppressive treatment. The rising incidence of hospital-acquired fungal infections, particularly in intensive care and surgical settings, is also creating significant therapeutic demand. Drug development is shifting toward more targeted, low-toxicity compounds that address resistance issues, especially in cases involving Candida and Aspergillus species.

Oral, topical, and intravenous formulations continue to evolve through advances in delivery technologies that improve treatment adherence and clinical outcomes. Increased emphasis on antifungal stewardship programs is encouraging more rational prescribing and boosting the uptake of newer therapeutic classes. Opportunities are emerging through the expansion of outpatient treatment, direct-to-consumer sales for topical applications, and rising interest in fixed-dose combinations. Ongoing innovation in formulation science and clinical diagnostics is helping identify infections earlier and tailor treatment more precisely, improving therapeutic success. Strong support from healthcare institutions, insurers, and regulatory agencies is accelerating product launches and facilitating patient access. The competitive environment remains dynamic, with pharmaceutical firms prioritizing lifecycle management, strategic collaborations, and niche-focused R&D to secure market advantage. The U.S. antifungal drugs market is poised for steady growth, driven by the need for safe, effective, and accessible antifungal therapies that can meet the demands of acute and chronic care environments.

U.S. Antifungal Drugs Market Report Highlights

By drug class, the azoles drug segment accounted for ~48% of the revenue share in 2024 due to their broad-spectrum efficacy against both superficial and systemic fungal infections. Its established clinical safety makes it a preferred treatment across healthcare settings.

Based on indication, the Candidiasis segment held the largest revenue share in 2024 due to its widespread occurrence across various patient populations.

A few key players include Abbott; Astellas Pharma, Inc.; Bayer AG; Enzon Pharmaceuticals, Inc.; Glenmark; GSK plc; Merck & Co., Inc.; Novartis AG; Pfizer, Inc.; and Sanofi.

Polaris Market Research has segmented the U.S. antifungal drugs market report on the basis of drug class, indication, dosage form, and distribution channel:

By Drug Class Outlook (Revenue, USD Billion, 2020–2034)

Azoles

Echinocandins

Polyenes

Allylamines

Others

By Indication Outlook (Revenue, USD Billion, 2020–2034)

Dermatophytosis

Aspergillosis

Candidiasis

Others

By Dosage Form Outlook (Revenue, USD Billion, 2020–2034)

Oral Drugs

Ointments

Powders

Others

By Distribution Channel Outlook (Revenue, USD Billion, 2020–2034)

Hospital Pharmacies

Retail Pharmacies

Others

Table of Contents

128 Pages
1. Introduction
1.1. Report Description
1.1.1. Objectives of the Study
1.1.2. Market Scope
1.1.3. Assumptions
1.2. Stakeholders
2. Executive Summary
2.1. Market Highlights
3. Research Methodology
3.1. Overview
3.1.1. Data Mining
3.2. Data Sources
3.2.1. Primary Sources
3.2.2. Secondary Sources
4. U.S. Antifungal Drugs Market Insights
4.1. U.S. Antifungal Drugs Market – Market Snapshot
4.2. U.S. Antifungal Drugs Market Dynamics
4.2.1. Drivers and Opportunities
4.2.1.1. High Prevalence of Immunocompromised Patients
4.2.1.2. Increasing Hospital-Acquired Fungal Infections
4.2.2. Restraints and Challenges
4.2.2.1. High costs of the products
4.3. Porter’s Five Forces Analysis
4.3.1. Bargaining Power of Suppliers (Moderate)
4.3.2. Threats of New Entrants: (Low)
4.3.3. Bargaining Power of Buyers (Moderate)
4.3.4. Threat of Substitute (Moderate)
4.3.5. Rivalry among existing firms (High)
4.4. PESTEL Analysis
4.5. U.S. Antifungal Drugs Market Power Rating Trends
4.6. Value Chain Analysis
5. U.S. Antifungal Drugs Market, by Drug Class
5.1. Key Findings
5.2. Introduction
5.2.1. U.S. Antifungal Drugs Market, by Drug Class, 2020-2034 (USD Billion)
5.3. Azoles
5.3.1. U.S. Antifungal Drugs Market, by Azoles, 2020-2034 (USD Billion)
5.4. Echinocandins
5.4.1. U.S. Antifungal Drugs Market, by Echinocandins, 2020-2034 (USD Billion)
5.5. Polyenes
5.5.1. U.S. Antifungal Drugs Market, by Polyenes, 2020-2034 (USD Billion)
5.6. Allylamines
5.6.1. U.S. Antifungal Drugs Market, by Allylamines, 2020-2034 (USD Billion)
5.7. Others
5.7.1. U.S. Antifungal Drugs Market, by Others, 2020-2034 (USD Billion)
6. U.S. Antifungal Drugs Market, by Indication
6.1. Key Findings
6.2. Introduction
6.2.1. U.S. Antifungal Drugs Market, By Indication, 2020-2034 (USD Billion)
6.3. Dermatophytosis
6.3.1. U.S. Antifungal Drugs Market, by Dermatophytosis, 2020-2034 (USD Billion)
6.4. Aspergillosis
6.4.1. U.S. Antifungal Drugs Market, by Aspergillosis, 2020-2034 (USD Billion)
6.5. Candidiasis
6.5.1. U.S. Antifungal Drugs Market, by Candidiasis, 2020-2034 (USD Billion)
6.6. Others
6.6.1. U.S. Antifungal Drugs Market, by Others, 2020-2034 (USD Billion)
7. U.S. Antifungal Drugs Market, by Dosage Form
7.1. Key Findings
7.2. Introduction
7.2.1. U.S. Antifungal Drugs Market, by Dosage Form, 2020-2034 (USD Billion)
7.3. Oral Drugs
7.3.1. U.S. Antifungal Drugs Market, by Oral Drugs, 2020-2034 (USD Billion)
7.4. Ointments
7.4.1. U.S. Antifungal Drugs Market, by Ointments, 2020-2034 (USD Billion)
7.5. Powders
7.5.1. U.S. Antifungal Drugs Market, by Powders, 2020-2034 (USD Billion)
7.6. Others
7.6.1. U.S. Antifungal Drugs Market, by Others, 2020-2034 (USD Billion)
8. U.S. Antifungal Drugs Market, by Distribution Channel
8.1. Key Findings
8.2. Introduction
8.2.1. U.S. Antifungal Drugs Market, by Distribution Channel, 2020-2034 (USD Billion)
8.3. Hospital Pharmacies
8.3.1. U.S. Antifungal Drugs Market, by Hospital Pharmacies, 2020-2034 (USD Billion)
8.4. Retail Pharmacies
8.4.1. U.S. Antifungal Drugs Market, by Retail Pharmacies, 2020-2034 (USD Billion)
8.5. Others
8.5.1. U.S. Antifungal Drugs Market, by Others, 2020-2034 (USD Billion)
9. Competitive Landscape
9.1. Expansion and Acquisition Analysis
9.1.1. Expansion
9.1.2. Acquisitions
9.2. Partnerships/Collaborations/Agreements/Exhibitions
10. Company Profiles
10.1. Abbott
10.1.1. Company Overview
10.1.2. Financial Performance
10.1.3. Product Benchmarking
10.1.4. Recent Development
10.2. Astellas Pharma, Inc.
10.2.1. Company Overview
10.2.2. Financial Performance
10.2.3. Product Benchmarking
10.2.4. Recent Development
10.3. Bayer AG
10.3.1. Company Overview
10.3.2. Financial Performance
10.3.3. Product Benchmarking
10.3.4. Recent Development
10.4. Enzon Pharmaceuticals, Inc.
10.4.1. Company Overview
10.4.2. Financial Performance
10.4.3. Product Benchmarking
10.4.4. Recent Development
10.5. Glenmark
10.5.1. Company Overview
10.5.2. Financial Performance
10.5.3. Product Benchmarking
10.5.4. Recent Development
10.6. GSK plc
10.6.1. Company Overview
10.6.2. Financial Performance
10.6.3. Product Benchmarking
10.6.4. Recent Development
10.7. Merck & Co., Inc.
10.7.1. Company Overview
10.7.2. Financial Performance
10.7.3. Product Benchmarking
10.7.4. Recent Development
10.8. Novartis AG
10.8.1. Company Overview
10.8.2. Financial Performance
10.8.3. Product Benchmarking
10.8.4. Recent Development
10.9. Pfizer, Inc
10.9.1. Company Overview
10.9.2. Financial Performance
10.9.3. Product Benchmarking
10.9.4. Recent Development
10.10. Sanofi
10.10.1. Company Overview
10.10.2. Financial Performance
10.10.3. Product Benchmarking
10.10.4. Recent Development
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