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Anti-VEGF Market by Product Type, End-Users, and Geography (North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa): Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2025 - 2032

Published Jul 24, 2025
Length 190 Pages
SKU # PERR20220175

Description

Persistence Market Research has recently released a comprehensive report on the worldwide market for anti-VEGF therapeutics. The report offers a thorough assessment of crucial market dynamics, including drivers, trends, opportunities, and challenges, providing detailed insights into the market structure.

Key Insights:
  • Anti-VEGF Market Size (2025E): USD 25.2 Billion
  • Projected Market Value (2032F): USD 33.1 Billion
  • Global Market Growth Rate (CAGR 2025 to 2032): 4.0%
Anti-VEGF Market - Report Scope:

Anti-VEGF (Vascular Endothelial Growth Factor) therapies play a crucial role in the treatment of various medical conditions, including age-related macular degeneration (AMD), diabetic macular edema (DME), retinal vein occlusion (RVO), and several cancers such as colorectal, lung, and kidney cancers. These drugs inhibit the VEGF protein, which promotes abnormal blood vessel formation, thereby reducing disease progression and preserving vision or slowing tumor growth. The anti-VEGF market caters to hospitals, ophthalmology clinics, oncology centers, and specialty medical institutions, offering a range of therapeutics including ranibizumab, aflibercept, bevacizumab, and their biosimilars. Market growth is driven by increasing prevalence of chronic diseases, growing geriatric population, and ongoing advancements in biologics and drug delivery technologies that improve therapeutic outcomes and patient compliance.

Market Growth Drivers:

The global anti-VEGF market is propelled by several key factors, including growing awareness about anti-VEGF therapies as targeted treatments for retinal and cancer conditions. The rising incidence of AMD and diabetes-related eye diseases, along with an increasing number of cancer cases worldwide, further fuels the demand for these therapies. Technological advancements such as sustained-release formulations, improved intravitreal delivery systems, and personalized medicine approaches have enhanced treatment precision, efficiency, and patient convenience. Moreover, increasing healthcare expenditure, rapid urbanization, and growing access to advanced treatment options in emerging economies contribute significantly to the overall market expansion.

Market Restraints:

Despite promising growth prospects, the anti-VEGF market faces challenges related to high treatment costs, reimbursement limitations, and potential safety concerns associated with repeated or long-term use. Stringent regulatory frameworks for approval and post-marketing surveillance of biologic drugs add to manufacturers’ compliance burden and may delay product launches. Additionally, the invasive nature of intravitreal injections and side effects such as ocular inflammation or elevated intraocular pressure may deter some patients from adhering to treatment schedules. Limited availability of skilled healthcare professionals for drug administration in low-resource settings further restricts market penetration.

Market Opportunities:

The anti-VEGF market presents significant growth opportunities driven by technological innovations, evolving treatment guidelines, and demographic shifts. The development of gene therapies, dual-pathway inhibitors, and refillable ocular implants can significantly improve patient adherence and clinical outcomes. Integration of telemedicine platforms and AI-assisted diagnostics enhances early detection and monitoring of retinal diseases, allowing for timely intervention. Expanding applications of anti-VEGF therapies in other disease areas such as nephropathy and certain inflammatory disorders also widen the market scope. Strategic investments in biosimilar development and affordable drug options for emerging markets offer potential for broader access and long-term growth.

Key Questions Answered in the Report:
  • What are the primary factors driving the growth of the anti-VEGF market globally?
  • Which drug types and applications are driving anti-VEGF adoption across different healthcare settings?
  • How are technological advancements reshaping the competitive landscape of the anti-VEGF market?
  • Who are the key players contributing to the anti-VEGF market, and what strategies are they employing to maintain market relevance?
  • What are the emerging trends and future prospects in the global anti-VEGF market?
Competitive Intelligence and Business Strategy:

These companies invest heavily in R\&D to develop long-acting, next-generation anti-VEGF formulations, dual-inhibition molecules, and biosimilar offerings. Collaborations with biotech startups, academic institutions, and contract manufacturing organizations accelerate drug development and reduce time-to-market. Moreover, patient-centric strategies, including support programs, co-pay assistance, and education initiatives, help improve therapy adoption and compliance in both developed and developing regions.

Key Companies Profiled:
  • Pfizer Inc.
  • Bayer AG
  • Novartis AG
  • Sanofi SA
  • Exelixis Inc.
  • Eisai Co. Ltd.
  • Amgen Inc.
  • F. Hoffmann-La Roche Ltd.
  • Eli Lilly and Company
  • Amneal Pharmaceuticals Inc.
  • Jiangsu Hengrui Pharmaceuticals Co. Ltd.
  • Takeda Pharmaceutical Co. Ltd.
  • Sino Biopharma
  • HUTCHMED
Anti-VEGF Market Research Segmentation:

By Drug:
  • Small Molecules
Pazopanib

Sunitinib

Sorafenib

Regorafenib

Cabozantinib

Lenvatinib

Ponatinib

Cabozantinib

Axitinib

Tivozanib

Vandetanib

Anlotinib

Apatinib

Fruquintinib

Surufatinib
  • Biologics
Bevacizumab

Aflibercept

Ramucirumab

By Type:
  • VEGF-A Inhibitors
  • VEGF-B Inhibitors
  • VEGF-C Inhibitors
  • Placenta Growth Factor Inhibitors
By Disease Indication:
  • Oncology
Non-Small Cell Lung Cancer

Renal Cell Carcinoma

Colorectal Cancer

Hepatocellular Carcinoma

Cervical Cancer

Others
  • Hematology Disorders
  • Ophthalmology Disorders
Wet Age-related Macular Degeneration (AMD)

Diabetic Retinopathy

Others

By Distribution Channel:
  • Hospitals
  • Specialty Clinics
  • Mail Order Pharmacies
By Region:
  • North America
  • Latin America
  • Europe
  • South Asia
  • East Asia
  • Oceania
  • Middle East and Africa


Please Note: It will take 5 business days to complete the report upon order confirmation.

Table of Contents

190 Pages
1. Executive Summary
1.1. Global Anti-VEGF Market Snapshot 2025 and 2032
1.2. Market Opportunity Assessment, 2025-2032, US$ Bn
1.3. Key Market Trends
1.4. Industry Developments and Key Market Events
1.5. Demand Side and Supply Side Analysis
1.6. PMR Analysis and Recommendations
2. Market Overview
2.1. Market Scope and Definitions
2.2. Value Chain Analysis
2.3. Macro-Economic Factors
2.3.1. Global GDP Outlook
2.3.2. Global GDP Outlook
2.3.3. Global economic Growth Forecast
2.3.4. Global Urbanization Growth
2.3.5. Other Macro-economic Factors
2.4. Forecast Factors – Relevance and Impact
2.5. COVID-19 Impact Assessment
2.6. PESTLE Analysis
2.7. Porter's Five Forces Analysis
2.8. Geopolitical Tensions: Market Impact
2.9. Regulatory and Technology Landscape
3. Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities
3.4. Trends
4. Price Trend Analysis, 2019-2032
4.1. Region-wise Price Analysis
4.2. Price by Segments
4.3. Price Impact Factors
5. Global Anti-VEGF Market Outlook: Historical (2019-2024) and Forecast (2025-2032)
5.1. Key Highlights
5.2. Global Anti-VEGF Market Outlook: Drug
5.2.1. Introduction/Key Findings
5.2.2. Historical Market Size (US$ Bn) Analysis by Drug, 2019-2024
5.2.3. Current Market Size (US$ Bn) Forecast, by Drug, 2025-2032
5.2.3.1. Small Molecules
5.2.3.1.1. Pazopanib
5.2.3.1.2. Sunitinib
5.2.3.1.3. Sorafenib
5.2.3.1.4. Regorafenib
5.2.3.1.5. Cabozantinib
5.2.3.1.6. Lenvatinib
5.2.3.2. Biologics
5.2.3.2.1. Bevacizumab
5.2.3.2.2. Aflibercept
5.2.3.2.3. Ramucirumab
5.2.4. Market Attractiveness Analysis: Drug
5.3. Global Anti-VEGF Market Outlook: Type
5.3.1. Introduction/Key Findings
5.3.2. Historical Market Size (US$ Bn) Analysis by Type, 2019-2024
5.3.3. Current Market Size (US$ Bn) Forecast, by Type, 2025-2032
5.3.3.1. VEGF-A Inhibitors
5.3.3.2. VEGF-B Inhibitors
5.3.3.3. VEGF-C Inhibitors
5.3.3.4. Placenta Growth Factor Inhibitors
5.3.4. Market Attractiveness Analysis: Type
5.4. Global Anti-VEGF Market Outlook: Disease Indication
5.4.1. Introduction/Key Findings
5.4.2. Historical Market Size (US$ Bn) Analysis by Disease Indication, 2019-2024
5.4.3. Current Market Size (US$ Bn) Forecast, by Disease Indication, 2025-2032
5.4.3.1. Oncology
5.4.3.2. Hematology Disorders
5.4.3.3. Ophthalmology Disorders
5.4.4. Market Attractiveness Analysis: Disease Indication
5.5. Global Anti-VEGF Market Outlook: Distribution Channel
5.5.1. Introduction/Key Findings
5.5.2. Historical Market Size (US$ Bn) Analysis by Distribution Channel, 2019-2024
5.5.3. Current Market Size (US$ Bn) Forecast, by Distribution Channel, 2025-2032
5.5.3.1. Hospitals
5.5.3.2. Specialty Clinics
5.5.3.3. Mail Order Pharmacies
5.5.4. Market Attractiveness Analysis: Distribution Channel
6. Global Anti-VEGF Market Outlook: Region
6.1. Key Highlights
6.2. Historical Market Size (US$ Bn) Analysis by Region, 2019-2024
6.3. Current Market Size (US$ Bn) Forecast, by Region, 2025-2032
6.3.1. North America
6.3.2. Europe
6.3.3. East Asia
6.3.4. South Asia & Oceania
6.3.5. Latin America
6.3.6. Middle East & Africa
6.4. Market Attractiveness Analysis: Region
7. North America Anti-VEGF Market Outlook: Historical (2019-2024) and Forecast (2025-2032)
7.1. Key Highlights
7.2. Pricing Analysis
7.3. North America Market Size (US$ Bn) Forecast, by Country, 2025-2032
7.3.1. U.S.
7.3.2. Canada
7.4. North America Market Size (US$ Bn) Forecast, by Drug, 2025-2032
7.4.1. Small Molecules
7.4.1.1. Pazopanib
7.4.1.2. Sunitinib
7.4.1.3. Sorafenib
7.4.1.4. Regorafenib
7.4.1.5. Cabozantinib
7.4.1.6. Lenvatinib
7.4.2. Biologics
7.4.2.1. Bevacizumab
7.4.2.2. Aflibercept
7.4.2.3. Ramucirumab
7.5. North America Market Size (US$ Bn) Forecast, by Type, 2025-2032
7.5.1. VEGF-A Inhibitors
7.5.2. VEGF-B Inhibitors
7.5.3. VEGF-C Inhibitors
7.5.4. Placenta Growth Factor Inhibitors
7.6. North America Market Size (US$ Bn) Forecast, by Disease Indication, 2025-2032
7.6.1. Oncology
7.6.2. Hematology Disorders
7.6.3. Ophthalmology Disorders
7.7. North America Market Size (US$ Bn) Forecast, by Distribution Channel, 2025-2032
7.7.1. Hospitals
7.7.2. Specialty Clinics
7.7.3. Mail Order Pharmacies
8. Europe Anti-VEGF Market Outlook: Historical (2019-2024) and Forecast (2025-2032)
8.1. Key Highlights
8.2. Pricing Analysis
8.3. Europe Market Size (US$ Bn) Forecast, by Country, 2025-2032
8.3.1. Germany
8.3.2. Italy
8.3.3. France
8.3.4. U.K.
8.3.5. Spain
8.3.6. Russia
8.3.7. Rest of Europe
8.4. Europe Market Size (US$ Bn) Forecast, by Drug, 2025-2032
8.4.1. Small Molecules
8.4.1.1. Pazopanib
8.4.1.2. Sunitinib
8.4.1.3. Sorafenib
8.4.1.4. Regorafenib
8.4.1.5. Cabozantinib
8.4.1.6. Lenvatinib
8.4.2. Biologics
8.4.2.1. Bevacizumab
8.4.2.2. Aflibercept
8.4.2.3. Ramucirumab
8.5. Europe Market Size (US$ Bn) Forecast, by Type, 2025-2032
8.5.1. VEGF-A Inhibitors
8.5.2. VEGF-B Inhibitors
8.5.3. VEGF-C Inhibitors
8.5.4. Placenta Growth Factor Inhibitors
8.6. Europe Market Size (US$ Bn) Forecast, by Disease Indication, 2025-2032
8.6.1. Oncology
8.6.2. Hematology Disorders
8.6.3. Ophthalmology Disorders
8.7. Europe Market Size (US$ Bn) Forecast, by Distribution Channel, 2025-2032
8.7.1. Hospitals
8.7.2. Specialty Clinics
8.7.3. Mail Order Pharmacies
9. East Asia Anti-VEGF Market Outlook: Historical (2019-2024) and Forecast (2025-2032)
9.1. Key Highlights
9.2. Pricing Analysis
9.3. East Asia Market Size (US$ Bn) Forecast, by Country, 2025-2032
9.3.1. China
9.3.2. Japan
9.3.3. South Korea
9.4. East Asia Market Size (US$ Bn) Forecast, by Drug, 2025-2032
9.4.1. Small Molecules
9.4.1.1. Pazopanib
9.4.1.2. Sunitinib
9.4.1.3. Sorafenib
9.4.1.4. Regorafenib
9.4.1.5. Cabozantinib
9.4.1.6. Lenvatinib
9.4.2. Biologics
9.4.2.1. Bevacizumab
9.4.2.2. Aflibercept
9.4.2.3. Ramucirumab
9.5. East Asia Market Size (US$ Bn) Forecast, by Type, 2025-2032
9.5.1. VEGF-A Inhibitors
9.5.2. VEGF-B Inhibitors
9.5.3. VEGF-C Inhibitors
9.5.4. Placenta Growth Factor Inhibitors
9.6. East Asia Market Size (US$ Bn) Forecast, by Disease Indication, 2025-2032
9.6.1. Oncology
9.6.2. Hematology Disorders
9.6.3. Ophthalmology Disorders
9.7. East Asia Market Size (US$ Bn) Forecast, by Distribution Channel, 2025-2032
9.7.1. Hospitals
9.7.2. Specialty Clinics
9.7.3. Mail Order Pharmacies
10. South Asia & Oceania Anti-VEGF Market Outlook: Historical (2019-2024) and Forecast (2025-2032)
10.1. Key Highlights
10.2. Pricing Analysis
10.3. South Asia & Oceania Market Size (US$ Bn) Forecast, by Country, 2025-2032
10.3.1. India
10.3.2. Southeast Asia
10.3.3. ANZ
10.3.4. Rest of SAO
10.4. South Asia & Oceania Market Size (US$ Bn) Forecast, by Drug, 2025-2032
10.4.1. Small Molecules
10.4.1.1. Pazopanib
10.4.1.2. Sunitinib
10.4.1.3. Sorafenib
10.4.1.4. Regorafenib
10.4.1.5. Cabozantinib
10.4.1.6. Lenvatinib
10.4.2. Biologics
10.4.2.1. Bevacizumab
10.4.2.2. Aflibercept
10.4.2.3. Ramucirumab
10.5. South Asia & Oceania Market Size (US$ Bn) Forecast, by Type, 2025-2032
10.5.1. VEGF-A Inhibitors
10.5.2. VEGF-B Inhibitors
10.5.3. VEGF-C Inhibitors
10.5.4. Placenta Growth Factor Inhibitors
10.6. South Asia & Oceania Market Size (US$ Bn) Forecast, by Disease Indication, 2025-2032
10.6.1. Oncology
10.6.2. Hematology Disorders
10.6.3. Ophthalmology Disorders
10.7. South Asia & Oceania Market Size (US$ Bn) Forecast, by Distribution Channel, 2025-2032
10.7.1. Hospitals
10.7.2. Specialty Clinics
10.7.3. Mail Order Pharmacies
11. Latin America Anti-VEGF Market Outlook: Historical (2019-2024) and Forecast (2025-2032)
11.1. Key Highlights
11.2. Pricing Analysis
11.3. Latin America Market Size (US$ Bn) Forecast, by Country, 2025-2032
11.3.1. Brazil
11.3.2. Mexico
11.3.3. Rest of LATAM
11.4. Latin America Market Size (US$ Bn) Forecast, by Drug, 2025-2032
11.4.1. Small Molecules
11.4.1.1. Pazopanib
11.4.1.2. Sunitinib
11.4.1.3. Sorafenib
11.4.1.4. Regorafenib
11.4.1.5. Cabozantinib
11.4.1.6. Lenvatinib
11.4.2. Biologics
11.4.2.1. Bevacizumab
11.4.2.2. Aflibercept
11.4.2.3. Ramucirumab
11.5. Latin America Market Size (US$ Bn) Forecast, by Type, 2025-2032
11.5.1. VEGF-A Inhibitors
11.5.2. VEGF-B Inhibitors
11.5.3. VEGF-C Inhibitors
11.5.4. Placenta Growth Factor Inhibitors
11.6. Latin America Market Size (US$ Bn) Forecast, by Disease Indication, 2025-2032
11.6.1. Oncology
11.6.2. Hematology Disorders
11.6.3. Ophthalmology Disorders
11.7. Latin America Market Size (US$ Bn) Forecast, by Distribution Channel, 2025-2032
11.7.1. Hospitals
11.7.2. Specialty Clinics
11.7.3. Mail Order Pharmacies
12. Middle East & Africa Anti-VEGF Market Outlook: Historical (2019-2024) and Forecast (2025-2032)
12.1. Key Highlights
12.2. Pricing Analysis
12.3. Middle East & Africa Market Size (US$ Bn) Forecast, by Country, 2025-2032
12.3.1. GCC Countries
12.3.2. South Africa
12.3.3. Northern Africa
12.3.4. Rest of MEA
12.4. Middle East & Africa Market Size (US$ Bn) Forecast, by Drug, 2025-2032
12.4.1. Small Molecules
12.4.1.1. Pazopanib
12.4.1.2. Sunitinib
12.4.1.3. Sorafenib
12.4.1.4. Regorafenib
12.4.1.5. Cabozantinib
12.4.1.6. Lenvatinib
12.4.2. Biologics
12.4.2.1. Bevacizumab
12.4.2.2. Aflibercept
12.4.2.3. Ramucirumab
12.5. Middle East & Africa Market Size (US$ Bn) Forecast, by Type, 2025-2032
12.5.1. VEGF-A Inhibitors
12.5.2. VEGF-B Inhibitors
12.5.3. VEGF-C Inhibitors
12.5.4. Placenta Growth Factor Inhibitors
12.6. Middle East & Africa Market Size (US$ Bn) Forecast, by Disease Indication, 2025-2032
12.6.1. Oncology
12.6.2. Hematology Disorders
12.6.3. Ophthalmology Disorders
12.7. Middle East & Africa Market Size (US$ Bn) Forecast, by Distribution Channel, 2025-2032
12.7.1. Hospitals
12.7.2. Specialty Clinics
12.7.3. Mail Order Pharmacies
13. Competition Landscape
13.1. Market Share Analysis, 2024
13.2. Market Structure
13.2.1. Competition Intensity Mapping
13.2.2. Competition Dashboard
13.3. Company Profiles
13.3.1. Pfizer Inc.
13.3.1.1. Company Overview
13.3.1.2. Product Portfolio/Offerings
13.3.1.3. Key Financials
13.3.1.4. SWOT Analysis
13.3.1.5. Company Strategy and Key Developments
13.3.2. Bayer AG
13.3.3. Novartis AG
13.3.4. Sanofi SA
13.3.5. Exelixis Inc.
13.3.6. Eisai Co. Ltd.
13.3.7. Amgen Inc.
13.3.8. F. Hoffmann-La Roche Ltd.
13.3.9. Eli Lilly and Company
13.3.10. Amneal Pharmaceuticals Inc.
13.3.11. Jiangsu Hengrui Pharmaceuticals Co. Ltd.
13.3.12. Takeda Pharmaceutical Co. Ltd.
13.3.13. Sino Biopharma
13.3.14. HUTCHMED
14. Appendix
14.1. Research Methodology
14.2. Research Assumptions
14.3. Acronyms and Abbreviations
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