
Age-related Macular Degeneration Market, Opportunity, Growth Drivers, Industry Trend Analysis and Forecast, 2025-2034
Description
The Global Age-related Macular Degeneration Market was valued at USD 10.1 billion in 2024 and is estimated to grow at a CAGR of 7.4%, to reach USD 20 billion by 2034, driven by a rising prevalence of AMD, an aging global population, increased awareness and early diagnosis, and ongoing innovations in treatment options. AMD is a progressive eye condition affecting individuals aged 50 and above, leading to central vision loss and significantly impacting quality of life.
AMD is a progressive eye condition that primarily affects individuals aged 50 and above, leading to irreversible central vision loss and significantly impairing daily activities such as reading, driving, and recognizing faces, ultimately impacting the overall quality of life. As the disease advances, it compromises the macula—the part of the retina responsible for sharp, central vision—resulting in blurred or dark spots in the visual field that cannot be corrected with glasses or contact lenses. This loss of independence often contributes to psychological effects such as anxiety, depression, and social isolation, especially among older adults. The growing burden of AMD is closely tied to the global aging trend, with its prevalence sharply increasing in populations over 65. The disease is also associated with other risk factors such as smoking, hypertension, obesity, genetic predisposition, and poor dietary habits—factors that are becoming more prevalent globally.
By disease type, wet AMD dominated the market with USD 9.4 billion in 2024, driven by the widespread adoption of anti-VEGF therapies, which have proven effective in halting disease progression, minimizing retinal fluid accumulation, and preserving visual function. The success of agents like Eylea, Lucentis, and Beovu has positioned wet AMD as the most actively treated form of the disease. Meanwhile, dry AMD, historically lacking approved pharmacologic interventions, is now seeing renewed clinical focus. The launch of Syfovre, the first FDA-approved treatment for geographic atrophy (a severe form of dry AMD), along with a promising pipeline of complement pathway inhibitors and gene therapies, signals a transformative shift in managing this segment.
Anti-VEGF therapies such as Eylea, Lucentis, and Vabysmo have become the cornerstone of AMD treatment. Among these, the Eylea segment led the market in 2024, generating USD 4.4 billion, owing to its efficacy in extending injection intervals and maintaining visual acuity. The drug's updated formulation, Eylea HD, is gaining further traction by offering extended dosing schedules that improve patient adherence and reduce treatment burden. New entrants like Vabysmo are rapidly gaining market share through dual-pathway inhibition (VEGF-A + Ang-2), addressing vascular instability and offering enhanced clinical outcomes.
North America Age-related Macular Degeneration Market will grow at a CAGR of 7% during 2025-2034, driven by robust healthcare infrastructure, early adoption of innovative therapies, and supportive regulatory frameworks. High diagnosis rates are further supported by widespread access to advanced imaging technologies such as OCT and an increasing focus on preventative eye care. Recent FDA approvals of novel, non-invasive therapies such as photobiomodulation for dry AMD underscore a regional shift toward less burdensome treatment modalities, aligning with patient preferences and improving long-term adherence.
To strengthen their position in the Age-related Macular Degeneration Market, companies like Xbrane Biopharma AB, Pfizer Inc., Formycon AG, Celltrion, Inc., Novartis AG, Amgen Inc., Sandoz Group AG, Apellis Pharmaceuticals, Inc., STADA Arzneimittel AG, F. Hoffmann-La Roche Ltd., Biocon Biologics Limited, Regeneron Pharmaceuticals Inc., Bayer AG, Biogen, Inc. are adopting strategic initiatives including R&D investments, biosimilar development, and long-acting formulations. Regeneron’s launch of Eylea HD and Roche’s introduction of Vabysmo demonstrate innovation-driven competition. Companies are also expanding through partnerships with CROs for clinical trials and leveraging digital tools for real-world data collection. Global market leaders focus on gene therapies, dual-pathway inhibitors, and complement-targeting drugs to diversify their portfolios. Additionally, pricing strategies, strategic licensing, and regulatory collaborations enable faster market access.
AMD is a progressive eye condition that primarily affects individuals aged 50 and above, leading to irreversible central vision loss and significantly impairing daily activities such as reading, driving, and recognizing faces, ultimately impacting the overall quality of life. As the disease advances, it compromises the macula—the part of the retina responsible for sharp, central vision—resulting in blurred or dark spots in the visual field that cannot be corrected with glasses or contact lenses. This loss of independence often contributes to psychological effects such as anxiety, depression, and social isolation, especially among older adults. The growing burden of AMD is closely tied to the global aging trend, with its prevalence sharply increasing in populations over 65. The disease is also associated with other risk factors such as smoking, hypertension, obesity, genetic predisposition, and poor dietary habits—factors that are becoming more prevalent globally.
By disease type, wet AMD dominated the market with USD 9.4 billion in 2024, driven by the widespread adoption of anti-VEGF therapies, which have proven effective in halting disease progression, minimizing retinal fluid accumulation, and preserving visual function. The success of agents like Eylea, Lucentis, and Beovu has positioned wet AMD as the most actively treated form of the disease. Meanwhile, dry AMD, historically lacking approved pharmacologic interventions, is now seeing renewed clinical focus. The launch of Syfovre, the first FDA-approved treatment for geographic atrophy (a severe form of dry AMD), along with a promising pipeline of complement pathway inhibitors and gene therapies, signals a transformative shift in managing this segment.
Anti-VEGF therapies such as Eylea, Lucentis, and Vabysmo have become the cornerstone of AMD treatment. Among these, the Eylea segment led the market in 2024, generating USD 4.4 billion, owing to its efficacy in extending injection intervals and maintaining visual acuity. The drug's updated formulation, Eylea HD, is gaining further traction by offering extended dosing schedules that improve patient adherence and reduce treatment burden. New entrants like Vabysmo are rapidly gaining market share through dual-pathway inhibition (VEGF-A + Ang-2), addressing vascular instability and offering enhanced clinical outcomes.
North America Age-related Macular Degeneration Market will grow at a CAGR of 7% during 2025-2034, driven by robust healthcare infrastructure, early adoption of innovative therapies, and supportive regulatory frameworks. High diagnosis rates are further supported by widespread access to advanced imaging technologies such as OCT and an increasing focus on preventative eye care. Recent FDA approvals of novel, non-invasive therapies such as photobiomodulation for dry AMD underscore a regional shift toward less burdensome treatment modalities, aligning with patient preferences and improving long-term adherence.
To strengthen their position in the Age-related Macular Degeneration Market, companies like Xbrane Biopharma AB, Pfizer Inc., Formycon AG, Celltrion, Inc., Novartis AG, Amgen Inc., Sandoz Group AG, Apellis Pharmaceuticals, Inc., STADA Arzneimittel AG, F. Hoffmann-La Roche Ltd., Biocon Biologics Limited, Regeneron Pharmaceuticals Inc., Bayer AG, Biogen, Inc. are adopting strategic initiatives including R&D investments, biosimilar development, and long-acting formulations. Regeneron’s launch of Eylea HD and Roche’s introduction of Vabysmo demonstrate innovation-driven competition. Companies are also expanding through partnerships with CROs for clinical trials and leveraging digital tools for real-world data collection. Global market leaders focus on gene therapies, dual-pathway inhibitors, and complement-targeting drugs to diversify their portfolios. Additionally, pricing strategies, strategic licensing, and regulatory collaborations enable faster market access.
Table of Contents
143 Pages
- Chapter 1 Methodology
- 1.1 Market segmentation
- 1.2 Market definitions
- 1.3 Research design
- 1.4 Market size estimates and calculations
- 1.4.1 Approach 1: Company share analysis
- 1.4.2 Approach 2: Bottom-up approach
- 1.4.3 Approach 3: Investor presentation approach
- 1.4.4 Approach 5: Top-down approach
- 1.4.5 Approach 6: Bottom-up revenue approach
- 1.5 Key trends for market estimates
- 1.6 Forecast model
- 1.7 Primary research & validation
- 1.7.1 Primary sources
- 1.7.2 Data mining sources
- 1.7.2.1 Paid sources
- 1.7.2.2 Public sources
- Chapter 2 Executive Summary
- 2.1 Global market 360° synopsis, 2021 - 2034
- 2.2 Product trends
- 2.3 Disease type trends
- 2.4 Age group trends
- 2.5 Distribution channel trends
- 2.6 Regional trends
- Chapter 3 Age-related macular degeneration Industry Insights
- 3.1 Industry ecosystem analysis
- 3.2 Industry impact forces
- 3.2.1 Growth drivers
- 3.2.1.1 Rising prevalence of Age-Related Macular Degeneration (AMD)
- 3.2.1.2 Growing aging population
- 3.2.1.3 Advancements in treatment options
- 3.2.2 Industry pitfalls and challenges
- 3.2.2.1 High cost of treatment
- 3.2.2.2 Risk of complications from intravitreal injection
- 3.3 Growth potential analysis
- 3.3.1 By product
- 3.3.2 By disease type
- 3.3.3 By age group
- 3.3.4 By distribution channel
- 3.4 Regulatory landscape
- 3.4.1 U.S.
- 3.4.2 Europe (excluding UK)
- 3.4.3 UK
- 3.4.4 India
- 3.4.5 Brazil
- 3.4.6 China
- 3.5 Technology landscape
- 3.5.1 Core technologies
- 3.5.2 Adjacent technologies
- 3.6 Future market trends
- 3.7 Patent analysis
- 3.8 Pipeline analysis
- 3.9 Clinical trial landscape
- 3.9.1 Approved therapies
- 3.9.2 Emerging biosimilars under clinical trials
- 3.10 Porter's analysis
- 3.11 PESTEL analysis
- Chapter 4 Competitive Landscape, 2024
- 4.1 Introduction
- 4.1.1 Regeneron Pharmaceuticals, Inc.
- 4.1.2 F. Hoffmann-La Roche Ltd.
- 4.1.3 Bayer AG
- 4.2 Company market share analysis
- 4.3 Company matrix analysis
- 4.4 Competitive analysis of major market players
- 4.5 Competitive positioning matrix
- 4.6 Strategy dashboard
- Chapter 5 Age-related macular degeneration Market, By Product
- 5.1 Eylea67
- 5.2 Lucentis
- 5.3 Beovu
- 5.4 Vabysmo
- 5.5 Syfovre
- 5.6 Avastin
- 5.7 Other products
- Chapter 6 Age-related macular degeneration Market, By Disease Type
- 6.1 Wet AMD
- 6.2 Dry AMD
- Chapter 7 Age-related macular degeneration Market, By Age Group
- 7.1 50-64 years
- 7.2 65-74 years
- 7.3 75 and above
- Chapter 8 Age-related macular degeneration Market, By Distribution Channel
- 8.1 Hospital pharmacies
- 8.2 Specialty and retail pharmacies
- 8.3 E-commerce
- Chapter 9 Age-related macular degeneration Market, By Region
- 9.1 North America
- 9.2 Europe
- 9.3 Asia Pacific
- 9.4 Latin America
- 9.5 Middle East and Africa
- Chapter 10 Company Profile
- 10.1 Amgen Inc.
- 10.1.1 Global overview
- 10.1.2 Business overview
- 10.1.3 Financial data
- 10.1.3.1 Annual sales revenue, 2021-2024 (USD Million)
- 10.1.4 Product landscape
- 10.1.5 Strategic outlook
- 10.1.6 SWOT analysis
- 10.2 Apellis Pharmaceuticals, Inc.
- 10.2.1 Global overview
- 10.2.2 Business overview
- 10.2.3 Financial data
- 10.2.3.1 Annual sales revenue, 2021-2024 (USD Million)
- 10.2.4 Product landscape
- 10.2.5 Strategic outlook
- 10.2.6 SWOT analysis
- 10.3 Astellas Pharma Inc.
- 10.3.1 Global overview
- 10.3.2 Business overview
- 10.3.3 Financial data
- 10.3.3.1 Annual sales revenue, 2021-2024 (USD Million)
- 10.3.4 Product landscape
- 10.3.5 Strategic outlook
- 10.3.6 SWOT analysis
- 10.4 Bayer AG
- 10.4.1 Global overview
- 10.4.2 Business overview
- 10.4.3 Financial data
- 10.4.3.1 Annual sales revenue, 2021 - 2024 (USD Million)
- 10.4.4 Product landscape
- 10.4.5 Strategic outlook
- 10.4.6 SWOT analysis
- 10.5 Biocon Biologics Limited
- 10.5.1 Global overview
- 10.5.2 Business overview
- 10.5.3 Financial data
- 10.5.3.1 Annual sales revenue, 2021-2024 (USD Million)
- 10.5.4 Product landscape
- 10.5.5 Strategic outlook
- 10.5.1 SWOT analysis
- 10.6 Biogen, Inc.
- 10.6.1 Global overview
- 10.6.2 Business overview
- 10.6.3 Financial data
- 10.6.3.1 Annual sales revenue, 2021-2024 (USD Million)
- 10.6.4 Product landscape
- 10.6.5 Strategic outlook
- 10.6.6 SWOT analysis
- 10.7 Celltrion, Inc.
- 10.7.1 Global overview
- 10.7.2 Business overview
- 10.7.3 Financial data
- 10.7.3.1 Annual sales revenue, 2021-2024 (USD Million)
- 10.7.4 Product landscape
- 10.7.5 Strategic outlook
- 10.7.6 SWOT analysis
- 10.8 F. Hoffmann-La Roche Ltd.
- 10.8.1 Global overview
- 10.8.2 Business overview
- 10.8.3 Financial data
- 10.8.3.1 Annual sales revenue, 2021 - 2024 (USD Million)
- 10.8.4 Product landscape
- 10.8.5 Strategic outlook
- 10.8.6 SWOT analysis
- 10.9 Formycon AG
- 10.9.1 Global overview
- 10.9.2 Business overview
- 10.9.3 Financial data
- 10.9.3.1 Annual sales revenue, 2021-2024 (USD Million)
- 10.9.4 Product landscape
- 10.9.5 Strategic outlook
- 10.9.6 SWOT analysis
- 10.10 Novartis AG
- 10.10.1 Global overview
- 10.10.2 Business overview
- 10.10.3 Financial data
- 10.10.3.1 Annual sales revenue, 2021-2024 (USD Million)
- 10.10.4 Product landscape
- 10.10.5 SWOT analysis
- 10.11 Pfizer Inc.
- 10.11.1 Global overview
- 10.11.2 Business overview
- 10.11.3 Financial data
- 10.11.3.1 Annual sales revenue, 2021-2024 (USD Million)
- 10.11.4 Product landscape
- 10.11.5 SWOT analysis
- 10.12 Regeneron Pharmaceuticals Inc.
- 10.12.1 Global overview
- 10.12.2 Business Overview
- 10.12.3 Financial data
- 10.12.3.1 Annual sales revenue, 2021-2024 (USD Million)
- 10.12.4 Product landscape
- 10.12.5 Strategic outlook
- 10.12.6 SWOT analysis
- 10.13 Sandoz Group AG
- 10.13.1 Global overview
- 10.13.2 Business overview
- 10.13.3 Financial data
- 10.13.3.1 Annual sales revenue, 2021-2024 (USD Million)
- 10.13.4 Product landscape
- 10.13.5 Strategic outlook
- 10.13.6 SWOT analysis
- 10.14 STADA Arzneimittel AG
- 10.14.1 Global overview
- 10.14.2 Business overview
- 10.14.3 Financial data
- 10.14.3.1 Annual sales revenue, 2020-2023 (USD Million)
- 10.14.4 Product landscape
- 10.14.5 Strategic outlook
- 10.14.6 SWOT analysis
- 10.15 Xbrane Biopharma AB
- 10.15.1 Global overview
- 10.15.2 Business overview
- 10.15.3 Financial data
- 10.15.3.1 Annual sales revenue, 2021-2024 (USD Million)
- 10.15.4 Product landscape
- 10.15.5 Strategic outlook
- 10.15.6 SWOT analysis
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