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Blood-Grouping Reagents Market Outlook 2026-2034: Market Share, and Growth Analysis By Technique (PCRbased and microarray techniques, Assaybased techniques, Massively parallel sequencing techniques, Serology ), By End-User (Hospitals and blood banks, Clin

Publisher OG Analysis
Published Nov 11, 2025
SKU # OGAN20568861

Description

The Blood-Grouping Reagents Market is valued at USD 1.33 billion in 2025 and is projected to grow at a CAGR of 7.8% to reach USD 2.76 billion by 2034.

Blood-Grouping Reagents Market

The Blood-Grouping Reagents Market encompasses antisera and ancillary consumables used to determine ABO/RhD groups, extended phenotypes, and antibody screens across transfusion services, donor centers, trauma networks, perioperative care, obstetrics, oncology, and a growing base of decentralized settings. The Blood-Grouping Reagents Market is propelled by rising procedure volumes, aging populations, hemovigilance mandates, and the expansion of patient blood management programs that demand accurate, rapid, and reproducible serology. Adoption spans conventional tube methods and gel/card column agglutination to solid-phase and microplate platforms, with automation increasingly integrated into high-throughput core labs and donor screening lines. Trends center on instrument–reagent lock systems for quality assurance, barcoded ready-to-use cassettes, liquid-stable monoclonal blends with enhanced avidity, and extended antigen panels supporting alloimmunization risk reduction in multi-transfused patients. Digital connectivity, LIS/EMR integration, and auto-verification reduce manual steps and transcription risk, while middleware consolidates QC, lot traceability, and competency management. Competitive dynamics include global IVD leaders, regional specialists, and OEM/private-label partnerships serving public blood programs and private hospital chains. Barriers persist around standardization across sites, reagent harmonization after formulary changes, and ensuring cold-chain integrity and lot-to-lot consistency. As healthcare systems prioritize speed-to-result, inventory stewardship, and hemolytic risk mitigation, next-generation reagents - paired with automation, standardized workflows, and decision support - are becoming foundational to safer transfusion pathways from donor recruitment to bedside administration.

Blood-Grouping Reagents Market Key Insights

Shift from manual to semi/fully automated workflowsLabs are migrating from tube testing to gel/solid-phase with conveyor-ready analyzers that consolidate forward/reverse grouping, RhD with weak-D, and antibody screens on a single platform. Automation reduces hands-on time, supports 24/7 operations, and stabilizes inter-operator variability, improving turnaround in trauma and perioperative settings where minutes matter.
Monoclonal reagent evolution boosts sensitivity and specificityHigh-affinity IgM/IgG blends, enzyme-enhanced formulations, and liquid-stable chemistries improve agglutination clarity and detection of weak subgroups and partial D variants. Standardized reaction profiles and anti-interference properties minimize equivocal outcomes, reducing reflex testing and conserving scarce technologist capacity.
Extended phenotyping/genotyping convergenceReagents for Kell, Duffy, Kidd, MNS, and other antigens increasingly sit alongside molecular assays in alloimmunization management programs. Serology defines routine phenotype while genotyping resolves complex serologic patterns and recent transfusion masking, enabling better matched units for oncology, hemoglobinopathy, and dialysis cohorts.
Instrument–reagent ecosystems and lockoutsClosed systems ensure reagent identification, lot traceability, and QC lockouts that prevent testing when controls fail or expiry is reached. This safeguards accreditation requirements, streamlines audits, and allows multi-site hospital networks to harmonize procedures and reduce corrective actions.
Connectivity, middleware, and decision supportAnalyzer–LIS integration with rules engines auto-verifies results within defined deltas, flags serologic discrepancies, and prompts reflex pathways (antibody ID, DAT, adsorption). Central dashboards aggregate QC and proficiency data, enabling remote oversight and standardized corrective action plans across the network.
Point-of-care and near-patient use casesEmergency and military medicine evaluate ruggedized cards and simplified cassettes for rapid screening when lab infrastructure is constrained. While confirmatory testing remains centralized, reliable preliminary grouping at the point of need shortens time to transfusion in mass-casualty or remote scenarios.
Quality systems and hemovigilance alignmentReagent lots ship with consolidated IFUs, value assignments, and electronic COAs; labs adopt risk-based QC frequencies and commutable controls. Standardized documentation supports incident trending, root-cause analysis, and continuous improvement tied to hemovigilance metrics.
Supply-chain resilience and cold-chain stewardshipVendors expand regional fill–finish and dual-sourcing of critical raw materials to buffer disruptions. Temperature indicators, smaller pack sizes, and extended on-board stability reduce wastage and help labs align ordering with episodic demand spikes.
Cost containment via utilization and consolidationHealth systems rationalize SKUs to core panels, negotiate reagent-rental models, and leverage automation to consolidate benches. Per-test economics improve through higher analyzer uptime, reduced repeats, and lower proficiency failure risk, sustaining budgets without compromising clinical safety.
Education, competency, and workforce sustainabilityStructured training, e-learning modules, and simulator QC reduce the learning curve for new staff and travelers. Clear visual endpoints and standardized grading criteria in gel/solid-phase aid consistent interpretation, supporting certification compliance and audit readiness.

Blood-Grouping Reagents Market Reginal Analysis

North America

Hospital consolidation and trauma network coordination favor high-throughput analyzers with closed reagent systems and robust LIS integration. Emphasis on hemovigilance, PBM, and rapid turnaround supports automation, while vendor-managed inventory and reagent-rental frameworks align with budget cycles and staffing constraints.

Europe

Stringent accreditation and procurement standards drive adoption of CE-marked, automation-ready reagents with comprehensive QC documentation. National blood services influence formulary choices and interoperability, and extended phenotyping support aligns with chronic transfusion programs and migrant health needs.

Asia-Pacific

Expanding hospital infrastructure and rising surgical volumes stimulate demand for scalable platforms from mid-volume labs to mega-centers. Public–private partnerships and local manufacturing improve access and cost control, while training initiatives address variability across urban and tier-2/3 settings.

Middle East & Africa

Investments in tertiary care and trauma readiness drive modernization from manual tube methods to gel/solid-phase in reference hubs. Priorities include supply continuity, heat-stable logistics, and vendor training programs; regional blood services increasingly standardize kits and QC to lift baseline reliability.

South & Central America

Public health systems and private chains balance affordability with quality by adopting semi-automation and reagent-rental models. Centralized reference labs support complex antibody workups, while stepwise upgrades in connectivity and QC programs enhance consistency across diverse geographies.

Blood-Grouping Reagents Market Segmentation

By Technique
  • PCRbased and microarray techniques
  • Assaybased techniques
  • Massively parallel sequencing techniques
  • Serology

    By End-User
  • Hospitals and blood banks
  • Clinical laboratories
  • Academic and research institutes

    Key Market players

    Bio-Rad Laboratories, QuidelOrtho (Ortho Clinical Diagnostics), Grifols, Immucor, Quotient Limited (ALBA Bioscience), DIAGAST, BAG Diagnostics, Lorne Laboratories, Sanquin Reagents, Hemo BioScience, Tulip Diagnostics, Pro-Lab Diagnostics, Rapid Labs, Fortress Diagnostics, Agappe Diagnostics

    Blood-Grouping Reagents Market Analytics

    The report employs rigorous tools, including Porter’s Five Forces, value chain mapping, and scenario-based modelling, to assess supply–demand dynamics. Cross-sector influences from parent, derived, and substitute markets are evaluated to identify risks and opportunities. Trade and pricing analytics provide an up-to-date view of international flows, including leading exporters, importers, and regional price trends.Macroeconomic indicators, policy frameworks such as carbon pricing and energy security strategies, and evolving consumer behaviour are considered in forecasting scenarios. Recent deal flows, partnerships, and technology innovations are incorporated to assess their impact on future market performance.

    Blood-Grouping Reagents Market Competitive Intelligence

    The competitive landscape is mapped through OG Analysis’ proprietary frameworks, profiling leading companies with details on business models, product portfolios, financial performance, and strategic initiatives. Key developments such as mergers & acquisitions, technology collaborations, investment inflows, and regional expansions are analyzed for their competitive impact. The report also identifies emerging players and innovative startups contributing to market disruption.Regional insights highlight the most promising investment destinations, regulatory landscapes, and evolving partnerships across energy and industrial corridors.

    Countries Covered

    • North America — Blood-Grouping Reagents market data and outlook to 2034
      • United States
      • Canada
      • Mexico
    • Europe — Blood-Grouping Reagents market data and outlook to 2034
      • Germany
      • United Kingdom
      • France
      • Italy
      • Spain
      • BeNeLux
      • Russia
      • Sweden
    • Asia-Pacific — Blood-Grouping Reagents market data and outlook to 2034
      • China
      • Japan
      • India
      • South Korea
      • Australia
      • Indonesia
      • Malaysia
      • Vietnam
    • Middle East and Africa — Blood-Grouping Reagents market data and outlook to 2034
      • Saudi Arabia
      • South Africa
      • Iran
      • UAE
      • Egypt
    • South and Central America — Blood-Grouping Reagents market data and outlook to 2034
      • Brazil
      • Argentina
      • Chile
      • Peru

    * We can include data and analysis of additional countries on demand.

    Research Methodology

    This study combines primary inputs from industry experts across the Blood-Grouping Reagents value chain with secondary data from associations, government publications, trade databases, and company disclosures. Proprietary modeling techniques, including data triangulation, statistical correlation, and scenario planning, are applied to deliver reliable market sizing and forecasting.

    Key Questions Addressed

  • What is the current and forecast market size of the Blood-Grouping Reagents industry at global, regional, and country levels?
  • Which types, applications, and technologies present the highest growth potential?
  • How are supply chains adapting to geopolitical and economic shocks?
  • What role do policy frameworks, trade flows, and sustainability targets play in shaping demand?
  • Who are the leading players, and how are their strategies evolving in the face of global uncertainty?
  • Which regional “hotspots” and customer segments will outpace the market, and what go-to-market and partnership models best support entry and expansion?
  • Where are the most investable opportunities—across technology roadmaps, sustainability-linked innovation, and M&A—and what is the best segment to invest over the next 3–5 years?

    Your Key Takeaways from the Blood-Grouping Reagents Market Report

    • Global Blood-Grouping Reagents market size and growth projections (CAGR), 2024-2034
    • Impact of Russia-Ukraine, Israel-Palestine, and Hamas conflicts on Blood-Grouping Reagents trade, costs, and supply chains
    • Blood-Grouping Reagents market size, share, and outlook across 5 regions and 27 countries, 2023-2034
    • Blood-Grouping Reagents market size, CAGR, and market share of key products, applications, and end-user verticals, 2023-2034
    • Short- and long-term Blood-Grouping Reagents market trends, drivers, restraints, and opportunities
    • Porter’s Five Forces analysis, technological developments, and Blood-Grouping Reagents supply chain analysis
    • Blood-Grouping Reagents trade analysis, Blood-Grouping Reagents market price analysis, and Blood-Grouping Reagents supply/demand dynamics
    • Profiles of 5 leading companies—overview, key strategies, financials, and products
    • Latest Blood-Grouping Reagents market news and developments

    • Table of Contents

    1. Table of Contents
    1.1 List of Tables
    1.2 List of Figures

    2. Global Blood-Grouping Reagents Market Summary, 2025
    2.1 Blood-Grouping Reagents Industry Overview
    2.1.1 Global Blood-Grouping Reagents Market Revenues (In US$ billion)
    2.2 Blood-Grouping Reagents Market Scope
    2.3 Research Methodology

    3. Blood-Grouping Reagents Market Insights, 2024-2034
    3.1 Blood-Grouping Reagents Market Drivers
    3.2 Blood-Grouping Reagents Market Restraints
    3.3 Blood-Grouping Reagents Market Opportunities
    3.4 Blood-Grouping Reagents Market Challenges
    3.5 Tariff Impact on Global Blood-Grouping Reagents Supply Chain Patterns

    4. Blood-Grouping Reagents Market Analytics
    4.1 Blood-Grouping Reagents Market Size and Share, Key Products, 2025 Vs 2034
    4.2 Blood-Grouping Reagents Market Size and Share, Dominant Applications, 2025 Vs 2034
    4.3 Blood-Grouping Reagents Market Size and Share, Leading End Uses, 2025 Vs 2034
    4.4 Blood-Grouping Reagents Market Size and Share, High Growth Countries, 2025 Vs 2034
    4.5 Five Forces Analysis for Global Blood-Grouping Reagents Market
    4.5.1 Blood-Grouping Reagents Industry Attractiveness Index, 2025
    4.5.2 Blood-Grouping Reagents Supplier Intelligence
    4.5.3 Blood-Grouping Reagents Buyer Intelligence
    4.5.4 Blood-Grouping Reagents Competition Intelligence
    4.5.5 Blood-Grouping Reagents Product Alternatives and Substitutes Intelligence
    4.5.6 Blood-Grouping Reagents Market Entry Intelligence

    5. Global Blood-Grouping Reagents Market Statistics – Industry Revenue, Market Share, Growth Trends and Forecast by segments, to 2034
    5.1 World Blood-Grouping Reagents Market Size, Potential and Growth Outlook, 2024- 2034 ($ billion)
    5.1 Global Blood-Grouping Reagents Sales Outlook and CAGR Growth By Technique, 2024- 2034 ($ billion)
    5.2 Global Blood-Grouping Reagents Sales Outlook and CAGR Growth By End-User, 2024- 2034 ($ billion)
    5.3 Global Blood-Grouping Reagents Sales Outlook and CAGR Growth By Segmentation3, 2024- 2034 ($ billion)
    5.4 Global Blood-Grouping Reagents Market Sales Outlook and Growth by Region, 2024- 2034 ($ billion)

    6. Asia Pacific Blood-Grouping Reagents Industry Statistics – Market Size, Share, Competition and Outlook
    6.1 Asia Pacific Blood-Grouping Reagents Market Insights, 2025
    6.2 Asia Pacific Blood-Grouping Reagents Market Revenue Forecast By Technique, 2024- 2034 (USD billion)
    6.3 Asia Pacific Blood-Grouping Reagents Market Revenue Forecast By End-User, 2024- 2034 (USD billion)
    6.4 Asia Pacific Blood-Grouping Reagents Market Revenue Forecast By Segmentation3, 2024- 2034 (USD billion)
    6.5 Asia Pacific Blood-Grouping Reagents Market Revenue Forecast by Country, 2024- 2034 (USD billion)
    6.5.1 China Blood-Grouping Reagents Market Size, Opportunities, Growth 2024- 2034
    6.5.2 India Blood-Grouping Reagents Market Size, Opportunities, Growth 2024- 2034
    6.5.3 Japan Blood-Grouping Reagents Market Size, Opportunities, Growth 2024- 2034
    6.5.4 Australia Blood-Grouping Reagents Market Size, Opportunities, Growth 2024- 2034

    7. Europe Blood-Grouping Reagents Market Data, Penetration, and Business Prospects to 2034
    7.1 Europe Blood-Grouping Reagents Market Key Findings, 2025
    7.2 Europe Blood-Grouping Reagents Market Size and Percentage Breakdown By Technique, 2024- 2034 (USD billion)
    7.3 Europe Blood-Grouping Reagents Market Size and Percentage Breakdown By End-User, 2024- 2034 (USD billion)
    7.4 Europe Blood-Grouping Reagents Market Size and Percentage Breakdown By Segmentation3, 2024- 2034 (USD billion)
    7.5 Europe Blood-Grouping Reagents Market Size and Percentage Breakdown by Country, 2024- 2034 (USD billion)
    7.5.1 Germany Blood-Grouping Reagents Market Size, Trends, Growth Outlook to 2034
    7.5.2 United Kingdom Blood-Grouping Reagents Market Size, Trends, Growth Outlook to 2034
    7.5.2 France Blood-Grouping Reagents Market Size, Trends, Growth Outlook to 2034
    7.5.2 Italy Blood-Grouping Reagents Market Size, Trends, Growth Outlook to 2034
    7.5.2 Spain Blood-Grouping Reagents Market Size, Trends, Growth Outlook to 2034

    8. North America Blood-Grouping Reagents Market Size, Growth Trends, and Future Prospects to 2034
    8.1 North America Snapshot, 2025
    8.2 North America Blood-Grouping Reagents Market Analysis and Outlook By Technique, 2024- 2034 ($ billion)
    8.3 North America Blood-Grouping Reagents Market Analysis and Outlook By End-User, 2024- 2034 ($ billion)
    8.4 North America Blood-Grouping Reagents Market Analysis and Outlook By Segmentation3, 2024- 2034 ($ billion)
    8.5 North America Blood-Grouping Reagents Market Analysis and Outlook by Country, 2024- 2034 ($ billion)
    8.5.1 United States Blood-Grouping Reagents Market Size, Share, Growth Trends and Forecast, 2024- 2034
    8.5.1 Canada Blood-Grouping Reagents Market Size, Share, Growth Trends and Forecast, 2024- 2034
    8.5.1 Mexico Blood-Grouping Reagents Market Size, Share, Growth Trends and Forecast, 2024- 2034

    9. South and Central America Blood-Grouping Reagents Market Drivers, Challenges, and Future Prospects
    9.1 Latin America Blood-Grouping Reagents Market Data, 2025
    9.2 Latin America Blood-Grouping Reagents Market Future By Technique, 2024- 2034 ($ billion)
    9.3 Latin America Blood-Grouping Reagents Market Future By End-User, 2024- 2034 ($ billion)
    9.4 Latin America Blood-Grouping Reagents Market Future By Segmentation3, 2024- 2034 ($ billion)
    9.5 Latin America Blood-Grouping Reagents Market Future by Country, 2024- 2034 ($ billion)
    9.5.1 Brazil Blood-Grouping Reagents Market Size, Share and Opportunities to 2034
    9.5.2 Argentina Blood-Grouping Reagents Market Size, Share and Opportunities to 2034

    10. Middle East Africa Blood-Grouping Reagents Market Outlook and Growth Prospects
    10.1 Middle East Africa Overview, 2025
    10.2 Middle East Africa Blood-Grouping Reagents Market Statistics By Technique, 2024- 2034 (USD billion)
    10.3 Middle East Africa Blood-Grouping Reagents Market Statistics By End-User, 2024- 2034 (USD billion)
    10.4 Middle East Africa Blood-Grouping Reagents Market Statistics By Segmentation3, 2024- 2034 (USD billion)
    10.5 Middle East Africa Blood-Grouping Reagents Market Statistics by Country, 2024- 2034 (USD billion)
    10.5.1 Middle East Blood-Grouping Reagents Market Value, Trends, Growth Forecasts to 2034
    10.5.2 Africa Blood-Grouping Reagents Market Value, Trends, Growth Forecasts to 2034

    11. Blood-Grouping Reagents Market Structure and Competitive Landscape
    11.1 Key Companies in Blood-Grouping Reagents Industry
    11.2 Blood-Grouping Reagents Business Overview
    11.3 Blood-Grouping Reagents Product Portfolio Analysis
    11.4 Financial Analysis
    11.5 SWOT Analysis

    12 Appendix
    12.1 Global Blood-Grouping Reagents Market Volume (Tons)
    12.1 Global Blood-Grouping Reagents Trade and Price Analysis
    12.2 Blood-Grouping Reagents Parent Market and Other Relevant Analysis
    12.3 Publisher Expertise
    12.2 Blood-Grouping Reagents Industry Report Sources and Methodology

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