Global Nucleic Acid Isolation and Purification Market

MARKET SCOPE:

The global Nucleic Acid Isolation and Purification market is projected to grow significantly, registering a CAGR of 8.3 % during the forecast period (2024 – 2032).

Nucleic acid isolation and purification are essential processes in molecular biology that involve the extraction and purification of DNA or RNA from biological samples. These techniques are fundamental for various applications, including genomic research, diagnostics, forensics, and biotechnology. The goal is to obtain high-quality nucleic acids that can be used reliably in downstream applications such as PCR, DNA sequencing, gene expression analysis, and cloning. Biological samples, such as blood, tissues, cells, or microorganisms, are collected based on the specific requirements of the experiment or application. The released nucleic acids (DNA or RNA) are then selectively bound to a solid-phase support or matrix. Commonly used materials for this purpose include silica-based membranes or magnetic beads. The increasing use of genetic testing for diagnostics, personalized medicine, and disease susceptibility assessments drives the demand for reliable nucleic acid isolation techniques.

MARKET OVERVIEW:

Driver: Growing Demand for need of genomic medicine is driving the market growth.

The increasing adoption of genomic medicine, which involves the use of an individual's genetic information for personalized healthcare, is driving the demand for nucleic acid technologies. These technologies enable the analysis of DNA and RNA for diagnostic and therapeutic purposes. Technological advancements, particularly in DNA sequencing technologies, have made genomic analysis more accessible and cost-effective. Next-generation sequencing (NGS) has revolutionized the field, enabling the efficient and comprehensive analysis of the entire genome. Governmental and private initiatives focused on precision medicine have spurred the adoption of genomic medicine. These initiatives aim to tailor medical treatments to individual patients based on their genetic makeup, improving treatment efficacy, and minimizing side effects. Growing biomedical research activities, including studies on genetics, genomics, and molecular biology, contribute to the demand for nucleic acid isolation and purification.

Opportunities: Rise of RNA therapeutics is expected to pave the way for the market growth in the upcoming years.

The development of RNA-based therapeutics, including mRNA vaccines and RNA interference (RNAi) therapies, is a significant driver. Nucleic acid technologies are crucial for the synthesis, delivery, and analysis of RNA molecules for therapeutic applications. RNA therapeutics have gained prominence due to their potential to target a wide range of diseases at the genetic level. The successful development and deployment of mRNA vaccines for infectious diseases, such as the COVID-19 vaccines, have been a groundbreaking achievement. This has demonstrated the effectiveness of using mRNA as a platform for developing vaccines against rapidly evolving pathogens. RNAi is a mechanism that allows the specific silencing of genes by introducing small RNA molecules. RNAi-based therapeutics have shown promise for treating various diseases, including genetic disorders and certain types of cancers.

COVID IMPACT:

The COVID – 19 positive impacts on the Nucleic Acid Isolation and Purification market were seen on various fronts that include the major vertical is the healthcare sector. The COVID-19 pandemic has had a profound impact on various sectors, including the life sciences and diagnostics industries. The increased demand for testing, research, and the development of vaccines and therapies has created positive effects on nucleic acid isolation and purification technologies. The need for widespread COVID-19 testing has driven a surge in demand for nucleic acid isolation and purification kits. These kits are essential for extracting viral RNA from patient samples, facilitating PCR-based diagnostic tests. The high demand for COVID-19 testing has driven innovations and advancements in nucleic acid extraction methods. Researchers and companies have worked to optimize and streamline these processes for higher throughput and efficiency. The need for rapid and decentralized testing has led to the expansion of point-of-care testing. Nucleic acid isolation technologies compatible with point-of-care settings have been developed, enabling quicker results and decentralized testing locations.

SEGMENTATION ANALYSIS:

The kit product type is anticipated to grow significantly during the forecast period

The increasing demand for molecular diagnostics, including tests for infectious diseases, genetic disorders, and cancer, has driven the development of nucleic acid kits. These kits enable the sensitive and specific detection of nucleic acid targets. Growing research in genomics and proteomics, which involves the study of genes and proteins, relies heavily on nucleic acid kits. Researchers use these kits for DNA and RNA extraction, amplification, and analysis to understand genetic variations and gene expression patterns. Polymerase Chain Reaction (PCR) and quantitative PCR (qPCR) are fundamental techniques in molecular biology. Nucleic acid kits designed for PCR and qPCR are widely used for DNA amplification and quantification, supporting applications such as gene expression analysis and genotyping. The adoption of NGS technologies for high-throughput sequencing relies on efficient nucleic acid preparation. Kits designed for DNA and RNA library preparation are essential for sample processing in NGS workflows. The global response to the COVID-19 pandemic has led to a surge in demand for nucleic acid isolation kits and technologies for virus detection through PCR and other methods. Advances in automation and high-throughput technologies enhance the efficiency and scalability of nucleic acid isolation, contributing to increased demand.

REGIONAL ANALYSIS:

The North American region is set to witness significant growth during the forecast period.

North America has been a hub for advancements in CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology. Researchers and biotech companies in the region have been exploring applications of CRISPR for gene editing, including therapeutic applications and agricultural biotechnology. The region has been at the forefront of developments in NGS technologies, enabling rapid and cost-effective sequencing of nucleic acids. This has applications in genomics, personalized medicine, and understanding the genetic basis of diseases. The groundbreaking development and successful deployment of mRNA-based vaccines, such as those for COVID-19, represent a major nucleic acid innovation. Several biotech companies in North America have been pioneers in mRNA technology. Advances in gene therapy, which often involve the use of nucleic acids to treat genetic disorders, have been a focus in North America. This includes the development of viral vectors and other delivery systems for introducing therapeutic nucleic acids into cells. Ongoing research and development efforts focus on improving existing isolation methods, developing new techniques, and enhancing the overall efficiency of nucleic acid isolation processes. The nucleic acid isolation and purification market is expected to grow due to the expanding applications in research, diagnostics, and industry. The increasing focus on precision medicine and personalized genomics further contributes to market growth. Emerging markets, including Asia-Pacific and Latin America, are becoming increasingly important in the nucleic acid isolation market as research activities and biotechnology applications expand globally.

COMPETITIVE ANALYSIS

The global Nucleic Acid Isolation and Purification market is reasonably competitive with mergers, acquisitions, and product launches. See some of the major key players in the market.

Agilent Technologies

• On January 9, 2023, Agilent Technologies announced a $725 million investment in nucleic acid-based therapies. Therapeutic nucleic acids, commonly known as therapeutic oligonucleotides or oligos, are small DNA and RNA molecules used as active pharmaceutical ingredients (API) in a variety of medications. The investment will be utilized to quadruple API manufacturing capacity.

Bio-Rad Laboratories Inc.

• On September, 2023, the PTC Tempo 48/48 and PTC Tempo 384 Thermal Cyclers, made to support PCR applications in basic and translational research, process development, and quality control, were just released by Bio-Rad Laboratories, Inc. a global leader in clinical diagnostic products and life science research. 

Danaher Corporation

GE Healthcare

Thermo Fisher Scientific

Hoffmann-La Roche Ltd,

Promega Corporation

Others

Scope of the Report

By Product

• Kits
• Reagents
• Instruments

By Type

• Genomic DNA
• Plasmid DNA
• MRNA

By Application

• Diagnostics
• Personalized Medicine

By Region

• North America (the United States & Canada)
• Europe (Germany, UK, France, Spain, Italy, and the Rest of Europe)
• Asia Pacific (China, Japan, India, and Rest of Asia Pacific)
• Rest of the World (the Middle East & Africa, and Latin America)

Key reasons to purchase this report

It provides a technological development map over time to understand the industry’s growth rate and indicates how the Nucleic Acid Isolation and Purification market is evolving.

The report offers a dynamic method to various factors that drive or restrain the growth of the market and specifies which Nucleic Acid Isolation and Purification submarket will be the main driver of the overall market from 2024 to 2032.

It renders a definite analysis of changing competitive dynamics and stipulates the leading players and what are their prospects over the forecast period.

It builds a nine-year estimate based on how the market is predicted to grow and shows what will market shares of the global region change by 2032 and which country will lead the market in 2032.