The global bFGF (FGF-2) market size is predicted to grow from US$ 165 million in 2025 to US$ 321 million in 2031; it is expected to grow at a CAGR of 11.7% from 2025 to 2031.
Basic fibroblast growth factor (bFGF, FGF-2) is a potent angiogenic factor and endothelial cell mitogen. Although bFGF levels are increased in chronically inflamed tissue, its role in inflammation is unclear. We investigated the effect of bFGF on acute dermal inflammation and the recruitment of monocytes, T cells, and neutrophils. Leukocyte recruitment to inflamed sites was quantified with radiolabeled leukocytes. Intradermal injection of bFGF in rats did not induce leukocyte recruitment or inflammation. However, the recruitment of leukocytes to inflammation induced by tumor necrosis factor-alpha, interferon-gamma, C5a, or a delayed hypersensitivity reaction was enhanced by bFGF by 55 to 132% (P < 0.05). Either acute or prolonged bFGF treatment of dermal sites had this effect. The potentiating effect of bFGF on leukocyte recruitment was also seen in joints. There was no associated modulation of vascular permeability, blood flow, or angiogenesis in the sites by bFGF. However, the expression of the endothelial cell adhesion molecules (CAMs) for leukocytes, P-selectin, E-selectin, and ICAM-1, was significantly up-regulated in the inflamed tissue by bFGF, as quantified by radiolabeled anti-CAM antibody binding in vivo. Thus, although not directly proinflammatory, bFGF synergistically potentiates inflammatory mediator-induced leukocyte recruitment, at least in part, by enhancing CAM up-regulation on endothelium.
United States market for bFGF (FGF-2) is estimated to increase from US$ million in 2024 to US$ million by 2031, at a CAGR of % from 2025 through 2031.
China market for bFGF (FGF-2) is estimated to increase from US$ million in 2024 to US$ million by 2031, at a CAGR of % from 2025 through 2031.
Europe market for bFGF (FGF-2) is estimated to increase from US$ million in 2024 to US$ million by 2031, at a CAGR of % from 2025 through 2031.
Global key bFGF (FGF-2) players cover Thermo Fisher Scientific, ProSpec, Corning, Essex Bio-Technology, Sino Biological, etc. In terms of revenue, the global two largest companies occupied for a share nearly % in 2024.
LPI (LP Information)' newest research report, the “bFGF (FGF-2) Industry Forecast” looks at past sales and reviews total world bFGF (FGF-2) sales in 2024, providing a comprehensive analysis by region and market sector of projected bFGF (FGF-2) sales for 2025 through 2031. With bFGF (FGF-2) sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world bFGF (FGF-2) industry.
This Insight Report provides a comprehensive analysis of the global bFGF (FGF-2) landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyses the strategies of leading global companies with a focus on bFGF (FGF-2) portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global bFGF (FGF-2) market.
This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for bFGF (FGF-2) and breaks down the forecast by Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global bFGF (FGF-2).
This report presents a comprehensive overview, market shares, and growth opportunities of bFGF (FGF-2) market by product type, application, key players and key regions and countries.
Segmentation by Type:
Vascular Endothelial Cell Source
Retinal Pigment Epithelial Cell Source
Other
Segmentation by Application:
Wound Healing
Neurodegenerative Diseases
Bone and Cartilage Repair
Cancer
Other
This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
Middle East & Africa
Egypt
South Africa
Israel
Turkey
GCC Countries
The below companies that are profiled have been selected based on inputs gathered from primary experts and analyzing the company's coverage, product portfolio, its market penetration.
Thermo Fisher Scientific
ProSpec
Corning
Essex Bio-Technology
Sino Biological
Lonza
Miltenyi Biotec
BioVendor
ScienCell Research Laboratories
Please note: The report will take approximately 2 business days to prepare and deliver.
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