Global -164? Ultra-low Temperature Freezers Market Growth 2026-2032
Description
The global -164℃ Ultra-low Temperature Freezers market size is predicted to grow from US$ 50.44 million in 2025 to US$ 67.75 million in 2032; it is expected to grow at a CAGR of 4.3% from 2026 to 2032.
A −164 °C ultra-low temperature freezer is often positioned as an ultra-deep/cryogenic freezer whose setpoint is far below conventional −80 °C ULT units. Typical products specify a chamber range around −120 °C to −164 °C, using compressor-based refrigeration with mixed refrigerants plus microprocessor temperature control to achieve stable operation at these extremes.
Upstream: Key upstream building blocks include the refrigeration train (compressors, heat exchangers, expansion/control components, piping, mixture refrigerants, sensors and a controller) and thermal containment (low heat-leak cabinet design, VIP vacuum insulation panels, thick insulation, gaskets/seals, and corrosion-resistant inner liners). Manufacturer specifications commonly highlight VIP insulation, microprocessor control with platinum RTD sensors, data logging, and multi-level audible/visual alarms.
Downstream: Downstream demand is concentrated in life science and medical storage and in special material low-temperature testing, covering samples such as DNA/RNA, tissues/skin, and biological products. In cell/tissue workflows, after an initial cool-down (often to −80 °C), long-term storage is commonly moved to below −135 °C (most often via liquid nitrogen in vapor or liquid phase), so −164 °C-class freezers can serve niches that require deeper mechanical storage or specific deep-cold conditions.
In 2025, global sales of −164 °C ultra-low temperature freezer reached approximately 1,653 units, with an average global market price of around US$ 31.2 K/unit. Production capacity varies significantly among manufacturers, with gross profit margins ranging from approximately 30% to 40%.
In life-science and healthcare workflows, ultra-deep mechanical freezers primarily serve samples that are highly sensitive to temperature excursions and require long-term, traceable storage. Demand is typically concentrated in biobanks, cell & gene therapy supply chains (from materials to final products), public-health laboratories, and advanced research institutions. As sample management becomes larger in scale and more standardized, decision makers increasingly look beyond the lowest achievable temperature and focus on long-run reliability, alarm and audit trails, energy and maintenance costs, and connectivity with laboratory informatics. As a result, this segment behaves more like specialized-capital procurement, where qualification, validation, and service readiness can be as important as core performance.
On the supply side, competition is shifting from pure cooling capability to full system engineering: compressor and mixed-refrigerant design choices, insulation architecture, temperature uniformity control, sensor strategy and calibration, and integrated software for remote monitoring and access control. Environmental refrigerants, noise and heat rejection, and stable operation under challenging power-grid conditions are also becoming more influential in institutional tenders. After a period of demand normalization, buyers are more lifecycle-cost driven and delivery-certain, which pushes manufacturers to invest continuously in quality systems, compliance credentials, and service networks.
Looking ahead, continued progress in cell therapy, synthetic biology, and biosecurity infrastructure should sustain installations and replacement demand, but growth is likely to be structural and project-based. Large accounts tend to prioritize brands with proven delivery scale and local service capability, while smaller users emphasize maintainability and value. For suppliers, defensible advantages in reliability validation, remote service, and response efficiency will largely determine their share ceiling in this niche.
LP Information, Inc. (LPI) ' newest research report, the “-164℃ Ultra-low Temperature Freezers Industry Forecast” looks at past sales and reviews total world -164℃ Ultra-low Temperature Freezers sales in 2025, providing a comprehensive analysis by region and market sector of projected -164℃ Ultra-low Temperature Freezers sales for 2026 through 2032. With -164℃ Ultra-low Temperature Freezers sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world -164℃ Ultra-low Temperature Freezers industry.
This Insight Report provides a comprehensive analysis of the global -164℃ Ultra-low Temperature Freezers landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyzes the strategies of leading global companies with a focus on -164℃ Ultra-low Temperature Freezers portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global -164℃ Ultra-low Temperature Freezers market.
This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for -164℃ Ultra-low Temperature Freezers and breaks down the forecast by Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global -164℃ Ultra-low Temperature Freezers.
This report presents a comprehensive overview, market shares, and growth opportunities of -164℃ Ultra-low Temperature Freezers market by product type, application, key manufacturers and key regions and countries.
Segmentation by Type:
Small Capacity
Medium Capacity
Large Capacity
Segmentation by Storage Phase:
Mechanical Dry Storage
LN₂ Vapor-Phase Storage
LN₂ Liquid-Phase Storage
Segmentation by Cabinet Configuration:
Chest Freezer
Upright Freezer
Segmentation by Application:
Corporate Laboratories
Hospitals and Blood Center
Universities and Research Institutions
Other
This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
Middle East & Africa
Egypt
South Africa
Israel
Turkey
GCC Countries
The below companies that are profiled have been selected based on inputs gathered from primary experts and analysing the company's coverage, product portfolio, its market penetration.
Zhongke Meiling Cryogenics
FASTER
Operon
Key Questions Addressed in this Report
What is the 10-year outlook for the global -164℃ Ultra-low Temperature Freezers market?
What factors are driving -164℃ Ultra-low Temperature Freezers market growth, globally and by region?
Which technologies are poised for the fastest growth by market and region?
How do -164℃ Ultra-low Temperature Freezers market opportunities vary by end market size?
How does -164℃ Ultra-low Temperature Freezers break out by Type, by Application?
Please note: The report will take approximately 2 business days to prepare and deliver.
A −164 °C ultra-low temperature freezer is often positioned as an ultra-deep/cryogenic freezer whose setpoint is far below conventional −80 °C ULT units. Typical products specify a chamber range around −120 °C to −164 °C, using compressor-based refrigeration with mixed refrigerants plus microprocessor temperature control to achieve stable operation at these extremes.
Upstream: Key upstream building blocks include the refrigeration train (compressors, heat exchangers, expansion/control components, piping, mixture refrigerants, sensors and a controller) and thermal containment (low heat-leak cabinet design, VIP vacuum insulation panels, thick insulation, gaskets/seals, and corrosion-resistant inner liners). Manufacturer specifications commonly highlight VIP insulation, microprocessor control with platinum RTD sensors, data logging, and multi-level audible/visual alarms.
Downstream: Downstream demand is concentrated in life science and medical storage and in special material low-temperature testing, covering samples such as DNA/RNA, tissues/skin, and biological products. In cell/tissue workflows, after an initial cool-down (often to −80 °C), long-term storage is commonly moved to below −135 °C (most often via liquid nitrogen in vapor or liquid phase), so −164 °C-class freezers can serve niches that require deeper mechanical storage or specific deep-cold conditions.
In 2025, global sales of −164 °C ultra-low temperature freezer reached approximately 1,653 units, with an average global market price of around US$ 31.2 K/unit. Production capacity varies significantly among manufacturers, with gross profit margins ranging from approximately 30% to 40%.
In life-science and healthcare workflows, ultra-deep mechanical freezers primarily serve samples that are highly sensitive to temperature excursions and require long-term, traceable storage. Demand is typically concentrated in biobanks, cell & gene therapy supply chains (from materials to final products), public-health laboratories, and advanced research institutions. As sample management becomes larger in scale and more standardized, decision makers increasingly look beyond the lowest achievable temperature and focus on long-run reliability, alarm and audit trails, energy and maintenance costs, and connectivity with laboratory informatics. As a result, this segment behaves more like specialized-capital procurement, where qualification, validation, and service readiness can be as important as core performance.
On the supply side, competition is shifting from pure cooling capability to full system engineering: compressor and mixed-refrigerant design choices, insulation architecture, temperature uniformity control, sensor strategy and calibration, and integrated software for remote monitoring and access control. Environmental refrigerants, noise and heat rejection, and stable operation under challenging power-grid conditions are also becoming more influential in institutional tenders. After a period of demand normalization, buyers are more lifecycle-cost driven and delivery-certain, which pushes manufacturers to invest continuously in quality systems, compliance credentials, and service networks.
Looking ahead, continued progress in cell therapy, synthetic biology, and biosecurity infrastructure should sustain installations and replacement demand, but growth is likely to be structural and project-based. Large accounts tend to prioritize brands with proven delivery scale and local service capability, while smaller users emphasize maintainability and value. For suppliers, defensible advantages in reliability validation, remote service, and response efficiency will largely determine their share ceiling in this niche.
LP Information, Inc. (LPI) ' newest research report, the “-164℃ Ultra-low Temperature Freezers Industry Forecast” looks at past sales and reviews total world -164℃ Ultra-low Temperature Freezers sales in 2025, providing a comprehensive analysis by region and market sector of projected -164℃ Ultra-low Temperature Freezers sales for 2026 through 2032. With -164℃ Ultra-low Temperature Freezers sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world -164℃ Ultra-low Temperature Freezers industry.
This Insight Report provides a comprehensive analysis of the global -164℃ Ultra-low Temperature Freezers landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyzes the strategies of leading global companies with a focus on -164℃ Ultra-low Temperature Freezers portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global -164℃ Ultra-low Temperature Freezers market.
This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for -164℃ Ultra-low Temperature Freezers and breaks down the forecast by Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global -164℃ Ultra-low Temperature Freezers.
This report presents a comprehensive overview, market shares, and growth opportunities of -164℃ Ultra-low Temperature Freezers market by product type, application, key manufacturers and key regions and countries.
Segmentation by Type:
Small Capacity
Medium Capacity
Large Capacity
Segmentation by Storage Phase:
Mechanical Dry Storage
LN₂ Vapor-Phase Storage
LN₂ Liquid-Phase Storage
Segmentation by Cabinet Configuration:
Chest Freezer
Upright Freezer
Segmentation by Application:
Corporate Laboratories
Hospitals and Blood Center
Universities and Research Institutions
Other
This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
Middle East & Africa
Egypt
South Africa
Israel
Turkey
GCC Countries
The below companies that are profiled have been selected based on inputs gathered from primary experts and analysing the company's coverage, product portfolio, its market penetration.
Zhongke Meiling Cryogenics
FASTER
Operon
Key Questions Addressed in this Report
What is the 10-year outlook for the global -164℃ Ultra-low Temperature Freezers market?
What factors are driving -164℃ Ultra-low Temperature Freezers market growth, globally and by region?
Which technologies are poised for the fastest growth by market and region?
How do -164℃ Ultra-low Temperature Freezers market opportunities vary by end market size?
How does -164℃ Ultra-low Temperature Freezers break out by Type, by Application?
Please note: The report will take approximately 2 business days to prepare and deliver.
Table of Contents
81 Pages
- *This is a tentative TOC and the final deliverable is subject to change.*
- 1 Scope of the Report
- 2 Executive Summary
- 3 Global by Company
- 4 World Historic Review for -164℃ Ultra-low Temperature Freezers by Geographic Region
- 5 Americas
- 6 APAC
- 7 Europe
- 8 Middle East & Africa
- 9 Market Drivers, Challenges and Trends
- 10 Manufacturing Cost Structure Analysis
- 11 Marketing, Distributors and Customer
- 12 World Forecast Review for -164℃ Ultra-low Temperature Freezers by Geographic Region
- 13 Key Players Analysis
- 14 Research Findings and Conclusion
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