Global Calculus Bovis Market Growth 2025-2031
Description
The global Calculus Bovis market size is predicted to grow from US$ 204 million in 2025 to US$ 509 million in 2031; it is expected to grow at a CAGR of 16.4% from 2025 to 2031.
The impact of the latest U.S. tariff measures and the corresponding policy responses from countries worldwide on market competitiveness, regional economic performance, and supply chain configurations will be comprehensively evaluated in this report.
Bezoar is a bovine gallstone used in traditional Chinese medicine. In countries such as China and Japan, it has long been used to treat a variety of diseases, including high fever, convulsions and stroke. In Asian countries, cattle stones are sometimes harvested when cattle are slaughtered. Bezoar is a dried gallstone of cattle, a mammal of the phylum Chordata. Those produced in the gallbladder are called "bile yellow" or "egg yolk", those produced in the bile duct are called "tube yellow", and those produced in the hepatic duct are called "liver yellow". The complete bezoar is mostly oval in shape, light in texture, with a golden to yellow-brown surface, delicate and shiny. Traditional Chinese medicine believes that bezoar has a fresh fragrance, a slightly bitter taste and then sweet, and a cool nature. It can be used to relieve fever, detoxify, and calm the nerves. It can be taken internally to treat high fever, coma, mania, infantile convulsions, convulsions, etc. It can be used externally to treat sore throat, mouth sores, carbuncle, and toxicity.
Because natural bezoar is extremely rare and cannot be produced industrially. Therefore, this report mainly counts two types of products: in vitro cultivated bezoar and artificial bezoar.
The global key manufacturers of calculus bovis include Jianmin Group, Dibo Pharmaceuticals, Mingxing Pharmaceuticals, Renqi Pharmaceuticals, Hongmao Pharmaceuticals, and Tongrentang. The top five manufacturers together account for 80% of the market share, with Jianmin Group being the largest producer with 20% of the market share. The global origin is mainly concentrated in China. At the consumer level, China holds close to 90% of the market share. In terms of product category, it is divided into in vitro calculus bovis and artificial bezoar, with the former having a higher market share of 75%. In terms of its application,preparations medicine is its top application area with 95% market share, followed by Chinese hebal medicine.
The driving factors of the bezoar market mainly include
1. Resource scarcity: rigid constraints on the supply of natural bezoar
Production bottleneck
Cause: Bezoar is a pathological product. Only 0.1%-0.2% of cattle gallstones can form natural bezoar, and the breeding cycle is long (requires 3-5 years).
2. Policy control: industry access and standard upgrade
Production license control
China only allows 6 companies (such as Jianmin Group and Tongrentang) to produce natural bezoar, and implements a quota system with an annual quota of less than 800 kilograms.
The 2025 edition of the "Chinese Pharmacopoeia" raises the detection standard for bezoar content, and the impurity limit is tightened from 2% to 0.5%, forcing companies to optimize procurement and processing technology.
3. Consumption upgrade: Demand for high-end Chinese medicine explodes
Chinese patent medicine field
Angong Niuhuang Wan: The core raw material bezoar accounts for 10%, and the annual demand exceeds 200 tons, driving the use of bezoar to increase by 15%.
Pianzaihuang: The unit price of natural bezoar formula products exceeds 1,000 yuan/tablet, and sales increase by 20% year-on-year.
Health products and cosmeceuticals extension
Bezoar toothpaste: adding trace amounts of bezoar ingredients, the unit price is 5 times that of ordinary toothpaste, and the market share increases by 25% annually.
Anti-aging products: bezoar extract is used for high-end skin care, and the target customer group CAGR reaches 30%.
IV. Technology substitution: breakthrough in in vitro cultivation of bezoar
Industrialization process is accelerated
Wuhan Jianmin Dapeng Pharmaceutical has achieved large-scale production of in vitro cultivated bezoar, with a cost of only 1/10 of natural bezoar and an annual production capacity of 5 tons.
Efficacy verification: The State Food and Drug Administration has approved it to replace natural bezoar for 42 kinds of Chinese patent medicines, covering 80% of bezoar preparations.
Market penetration rate increases
In vitro cultivated bezoar has a market share of more than 60% in the low- and medium-end markets, squeezing out the demand for natural bezoar, but it is still irreplaceable in the high-end field.
V. Capital drive: industrial chain integration and financialization
Upstream resource monopoly
Pianzihuang and Tongrentang lock in cattle sources by holding overseas ranches.
Futures and financial derivatives
Bezoar futures are listed on the Bozhou Chinese Medicine Exchange, with an annual trading volume of over 5 billion yuan. The price discovery function reduces corporate procurement risks.
6. Cultural beliefs: Traditional medical cognition is solidified
The status of the pharmacopoeia is unshakable
The "Shennong Bencao Jing" lists bezoar as a top-grade product, and its status as the first of the "three treasures of cold water" in traditional Chinese medicine theory deepens consumer cognition.
Gift attributes are strengthened
Natural bezoar products have become high-end gifts, and the annual sales of bezoar handicrafts with a unit price of more than 100,000 yuan exceeds 1 billion yuan.
7. Challenges and coping strategies
Sustainable supply problems
Countermeasures: Promote in vitro cultivation technology, develop synthetic biology pathways for bezoar, and reduce dependence on natural resources.
Price volatility risk
Countermeasures: Establish a national strategic reserve system, improve hedging tools in the futures market, and smooth the cost curve of enterprises.
The bezoar market is a typical scenario of resource scarcity, policy control, consumption upgrades and technological substitution resonance. In the future, the industry will present the triple trends of "high-end natural bezoar, large-scale in vitro cultivation, and financialization of the industrial chain." Enterprises need to seek a balance between supply constraints and demand explosion through technological breakthroughs, resource monopoly and cultural marketing, and dominate the market structure in the next decade.
LP Information, Inc. (LPI) ' newest research report, the “Calculus Bovis Industry Forecast” looks at past sales and reviews total world Calculus Bovis sales in 2024, providing a comprehensive analysis by region and market sector of projected Calculus Bovis sales for 2025 through 2031. With Calculus Bovis sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world Calculus Bovis industry.
This Insight Report provides a comprehensive analysis of the global Calculus Bovis landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyzes the strategies of leading global companies with a focus on Calculus Bovis portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global Calculus Bovis market.
This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for Calculus Bovis and breaks down the forecast by Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global Calculus Bovis.
This report presents a comprehensive overview, market shares, and growth opportunities of Calculus Bovis market by product type, application, key manufacturers and key regions and countries.
Segmentation by Type:
Artificial Bezoar
In Vitro Cultured Bezoar
Segmentation by Application:
Preparations Medicine
Chinese Herbal Medicine
This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
Middle East & Africa
Egypt
South Africa
Israel
Turkey
GCC Countries
The below companies that are profiled have been selected based on inputs gathered from primary experts and analysing the company's coverage, product portfolio, its market penetration.
Jianmin Group
Dibo Pharmaceuticals
Ming Hing Pharmaceutical
Renqi Pharmaceutical
Hongmao Pharmaceutical
Tongrentang
Key Questions Addressed in this Report
What is the 10-year outlook for the global Calculus Bovis market?
What factors are driving Calculus Bovis market growth, globally and by region?
Which technologies are poised for the fastest growth by market and region?
How do Calculus Bovis market opportunities vary by end market size?
How does Calculus Bovis break out by Type, by Application?
Please note: The report will take approximately 2 business days to prepare and deliver.
The impact of the latest U.S. tariff measures and the corresponding policy responses from countries worldwide on market competitiveness, regional economic performance, and supply chain configurations will be comprehensively evaluated in this report.
Bezoar is a bovine gallstone used in traditional Chinese medicine. In countries such as China and Japan, it has long been used to treat a variety of diseases, including high fever, convulsions and stroke. In Asian countries, cattle stones are sometimes harvested when cattle are slaughtered. Bezoar is a dried gallstone of cattle, a mammal of the phylum Chordata. Those produced in the gallbladder are called "bile yellow" or "egg yolk", those produced in the bile duct are called "tube yellow", and those produced in the hepatic duct are called "liver yellow". The complete bezoar is mostly oval in shape, light in texture, with a golden to yellow-brown surface, delicate and shiny. Traditional Chinese medicine believes that bezoar has a fresh fragrance, a slightly bitter taste and then sweet, and a cool nature. It can be used to relieve fever, detoxify, and calm the nerves. It can be taken internally to treat high fever, coma, mania, infantile convulsions, convulsions, etc. It can be used externally to treat sore throat, mouth sores, carbuncle, and toxicity.
Because natural bezoar is extremely rare and cannot be produced industrially. Therefore, this report mainly counts two types of products: in vitro cultivated bezoar and artificial bezoar.
The global key manufacturers of calculus bovis include Jianmin Group, Dibo Pharmaceuticals, Mingxing Pharmaceuticals, Renqi Pharmaceuticals, Hongmao Pharmaceuticals, and Tongrentang. The top five manufacturers together account for 80% of the market share, with Jianmin Group being the largest producer with 20% of the market share. The global origin is mainly concentrated in China. At the consumer level, China holds close to 90% of the market share. In terms of product category, it is divided into in vitro calculus bovis and artificial bezoar, with the former having a higher market share of 75%. In terms of its application,preparations medicine is its top application area with 95% market share, followed by Chinese hebal medicine.
The driving factors of the bezoar market mainly include
1. Resource scarcity: rigid constraints on the supply of natural bezoar
Production bottleneck
Cause: Bezoar is a pathological product. Only 0.1%-0.2% of cattle gallstones can form natural bezoar, and the breeding cycle is long (requires 3-5 years).
2. Policy control: industry access and standard upgrade
Production license control
China only allows 6 companies (such as Jianmin Group and Tongrentang) to produce natural bezoar, and implements a quota system with an annual quota of less than 800 kilograms.
The 2025 edition of the "Chinese Pharmacopoeia" raises the detection standard for bezoar content, and the impurity limit is tightened from 2% to 0.5%, forcing companies to optimize procurement and processing technology.
3. Consumption upgrade: Demand for high-end Chinese medicine explodes
Chinese patent medicine field
Angong Niuhuang Wan: The core raw material bezoar accounts for 10%, and the annual demand exceeds 200 tons, driving the use of bezoar to increase by 15%.
Pianzaihuang: The unit price of natural bezoar formula products exceeds 1,000 yuan/tablet, and sales increase by 20% year-on-year.
Health products and cosmeceuticals extension
Bezoar toothpaste: adding trace amounts of bezoar ingredients, the unit price is 5 times that of ordinary toothpaste, and the market share increases by 25% annually.
Anti-aging products: bezoar extract is used for high-end skin care, and the target customer group CAGR reaches 30%.
IV. Technology substitution: breakthrough in in vitro cultivation of bezoar
Industrialization process is accelerated
Wuhan Jianmin Dapeng Pharmaceutical has achieved large-scale production of in vitro cultivated bezoar, with a cost of only 1/10 of natural bezoar and an annual production capacity of 5 tons.
Efficacy verification: The State Food and Drug Administration has approved it to replace natural bezoar for 42 kinds of Chinese patent medicines, covering 80% of bezoar preparations.
Market penetration rate increases
In vitro cultivated bezoar has a market share of more than 60% in the low- and medium-end markets, squeezing out the demand for natural bezoar, but it is still irreplaceable in the high-end field.
V. Capital drive: industrial chain integration and financialization
Upstream resource monopoly
Pianzihuang and Tongrentang lock in cattle sources by holding overseas ranches.
Futures and financial derivatives
Bezoar futures are listed on the Bozhou Chinese Medicine Exchange, with an annual trading volume of over 5 billion yuan. The price discovery function reduces corporate procurement risks.
6. Cultural beliefs: Traditional medical cognition is solidified
The status of the pharmacopoeia is unshakable
The "Shennong Bencao Jing" lists bezoar as a top-grade product, and its status as the first of the "three treasures of cold water" in traditional Chinese medicine theory deepens consumer cognition.
Gift attributes are strengthened
Natural bezoar products have become high-end gifts, and the annual sales of bezoar handicrafts with a unit price of more than 100,000 yuan exceeds 1 billion yuan.
7. Challenges and coping strategies
Sustainable supply problems
Countermeasures: Promote in vitro cultivation technology, develop synthetic biology pathways for bezoar, and reduce dependence on natural resources.
Price volatility risk
Countermeasures: Establish a national strategic reserve system, improve hedging tools in the futures market, and smooth the cost curve of enterprises.
The bezoar market is a typical scenario of resource scarcity, policy control, consumption upgrades and technological substitution resonance. In the future, the industry will present the triple trends of "high-end natural bezoar, large-scale in vitro cultivation, and financialization of the industrial chain." Enterprises need to seek a balance between supply constraints and demand explosion through technological breakthroughs, resource monopoly and cultural marketing, and dominate the market structure in the next decade.
LP Information, Inc. (LPI) ' newest research report, the “Calculus Bovis Industry Forecast” looks at past sales and reviews total world Calculus Bovis sales in 2024, providing a comprehensive analysis by region and market sector of projected Calculus Bovis sales for 2025 through 2031. With Calculus Bovis sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world Calculus Bovis industry.
This Insight Report provides a comprehensive analysis of the global Calculus Bovis landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyzes the strategies of leading global companies with a focus on Calculus Bovis portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global Calculus Bovis market.
This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for Calculus Bovis and breaks down the forecast by Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global Calculus Bovis.
This report presents a comprehensive overview, market shares, and growth opportunities of Calculus Bovis market by product type, application, key manufacturers and key regions and countries.
Segmentation by Type:
Artificial Bezoar
In Vitro Cultured Bezoar
Segmentation by Application:
Preparations Medicine
Chinese Herbal Medicine
This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
Middle East & Africa
Egypt
South Africa
Israel
Turkey
GCC Countries
The below companies that are profiled have been selected based on inputs gathered from primary experts and analysing the company's coverage, product portfolio, its market penetration.
Jianmin Group
Dibo Pharmaceuticals
Ming Hing Pharmaceutical
Renqi Pharmaceutical
Hongmao Pharmaceutical
Tongrentang
Key Questions Addressed in this Report
What is the 10-year outlook for the global Calculus Bovis market?
What factors are driving Calculus Bovis market growth, globally and by region?
Which technologies are poised for the fastest growth by market and region?
How do Calculus Bovis market opportunities vary by end market size?
How does Calculus Bovis break out by Type, by Application?
Please note: The report will take approximately 2 business days to prepare and deliver.
Table of Contents
93 Pages
- *This is a tentative TOC and the final deliverable is subject to change.*
- 1 Scope of the Report
- 2 Executive Summary
- 3 Global by Company
- 4 World Historic Review for Calculus Bovis by Geographic Region
- 5 Americas
- 6 APAC
- 7 Europe
- 8 Middle East & Africa
- 9 Market Drivers, Challenges and Trends
- 10 Manufacturing Cost Structure Analysis
- 11 Marketing, Distributors and Customer
- 12 World Forecast Review for Calculus Bovis by Geographic Region
- 13 Key Players Analysis
- 14 Research Findings and Conclusion
Pricing
Currency Rates
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