Global Bio-Layer Interferometry (BLI) Systems Market Growth 2025-2031

The global Bio-Layer Interferometry (BLI) Systems market size is predicted to grow from US$ 395 million in 2025 to US$ 642 million in 2031; it is expected to grow at a CAGR of 8.4% from 2025 to 2031.

Bio-Layer Interferometry (BLI) Systems are advanced optical biosensing instruments that operate based on the principle of detecting changes in the interference pattern of light reflected from a biosensor tip as biomolecular interactions, such as protein-protein, protein-small molecule, or antibody-antigen interactions, take place on its surface. They offer real-time, label-free analysis capabilities, enabling precise quantification of binding kinetics and affinity, and are widely utilized in diverse fields like drug discovery, antibody engineering, and biomedical research.

Bio-Layer Interferometry (BLI) systems are gaining significant traction in the life sciences, especially for applications related to biomolecular interaction analysis and biosensor technologies. Here are some current market trends:

BLI is increasingly being used in the development of biologics and vaccines, as it allows for label-free and real-time monitoring of molecular interactions. It’s especially helpful in early-stage drug discovery to analyze binding affinities and kinetics.

Pharmaceutical companies are adopting BLI technologies to streamline the drug development process and reduce costs, which is driving market growth.

Manufacturers are focusing on enhancing the sensitivity, throughput, and usability of BLI systems. Developments such as multi-channel systems that can analyze several interactions simultaneously are gaining popularity.

Integration with other technologies, like microfluidics and artificial intelligence, is helping to make BLI systems more precise and adaptable to complex experimental setups.

Beyond research and development, BLI technology is being explored for clinical diagnostics, particularly in detecting biomarkers and monitoring therapeutic responses. This has widened the scope of BLI applications beyond research labs.

The growing emphasis on personalized medicine has fueled interest in BLI for analyzing specific patient responses at the molecular level.

The adoption of BLI technology by academic institutions and contract research organizations (CROs) is on the rise. Many of these organizations require advanced technologies for studying protein-protein interactions, which is where BLI is especially useful.

Government funding for life sciences research is also a key driver, encouraging the use of sophisticated platforms like BLI.

LP Information, Inc. (LPI) ' newest research report, the “Bio-Layer Interferometry (BLI) Systems Industry Forecast” looks at past sales and reviews total world Bio-Layer Interferometry (BLI) Systems sales in 2024, providing a comprehensive analysis by region and market sector of projected Bio-Layer Interferometry (BLI) Systems sales for 2025 through 2031. With Bio-Layer Interferometry (BLI) Systems sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world Bio-Layer Interferometry (BLI) Systems industry.

This Insight Report provides a comprehensive analysis of the global Bio-Layer Interferometry (BLI) Systems landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyzes the strategies of leading global companies with a focus on Bio-Layer Interferometry (BLI) Systems portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global Bio-Layer Interferometry (BLI) Systems market.

This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for Bio-Layer Interferometry (BLI) Systems and breaks down the forecast by Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global Bio-Layer Interferometry (BLI) Systems.

This report presents a comprehensive overview, market shares, and growth opportunities of Bio-Layer Interferometry (BLI) Systems market by product type, application, key manufacturers and key regions and countries.

Segmentation by Type:
Low and Medium Throughput
High Throughput

Segmentation by Application:
Drug Discovery
Antibody Engineering
Others

This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
Middle East & Africa
Egypt
South Africa
Israel
Turkey
GCC Countries

The below companies that are profiled have been selected based on inputs gathered from primary experts and analysing the company's coverage, product portfolio, its market penetration.
Sartorius (ForteBio)
Gator Bio

Key Questions Addressed in this Report

What is the 10-year outlook for the global Bio-Layer Interferometry (BLI) Systems market?

What factors are driving Bio-Layer Interferometry (BLI) Systems market growth, globally and by region?

Which technologies are poised for the fastest growth by market and region?

How do Bio-Layer Interferometry (BLI) Systems market opportunities vary by end market size?

How does Bio-Layer Interferometry (BLI) Systems break out by Type, by Application?

Please note: The report will take approximately 2 business days to prepare and deliver.