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Oligonucleotide CDMO Market Size, Share & Trends Analysis Report By Service (Contract Development, Contract Manufacturing), By Type (Antisense Oligonucleotides, Small Interfering RNA), By Application, By End-use, By Region, And Segment Forecasts, 2025 - 2

Publisher Grand View Research
Published Dec 04, 2025
Length 150 Pages
SKU # GV20723754

Description

Oligonucleotide CDMO Market Summary

The global oligonucleotide CDMO market size was estimated at USD 911.78 million in 2024 and is projected to reach USD 3,168.97 million by 2033, growing at a CAGR of 14.98% from 2025 to 2033. The market is driven by the rising clinical pipeline of antisense and siRNA therapies, growing adoption of mRNA-based therapeutics beyond vaccines, and increasing outsourcing by biotech firms to reduce manufacturing complexity.

In addition, the increasing number of pipeline of RNA-based and antisense therapeutics is driving the need for specialized manufacturing partners to help them scale production. As these candidates progress into late-stage clinical trials, sponsors encounter capacity constraints and heightened purity requirements, prompting a shift toward experienced contract development and manufacturing organizations (CDMOs) for scalable and compliant production. The need for consistent GMP-grade materials across multiple development phases further strengthens outsourcing trends and supports the steady uptake of contract manufacturing services in this domain.

Furthermore, the growing complexity of oligonucleotide chemistry, which requires sophisticated synthesis platforms and analytical capabilities that many emerging biotech firms cannot develop internally is also contributing to market growth. Several advancements such as conjugated oligos, advanced delivery systems, and long-chain sequences is adding additional technical challenges which is encouraging companies to depend on CDMOs with proven expertise. Thus, technologically advanced providers that can deliver high yield, reduced impurity profiles, and flexible batch scaling are becoming crucial across the development range.

Global Oligonucleotide CDMO Market Report Segmentation

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Grand View Research has segmented the global oligonucleotide CDMO market report based on service, type, application, end use, and region:
  • Service Outlook (Revenue, USD Million, 2021 - 2033)
  • Contract Manufacturing
  • Contract Development
  • Type Outlook (Revenue, USD Million, 2021 - 2033)
  • Antisense Oligonucleotides
  • Small Interfering RNA
  • Other Oligonucleotides
  • Application Outlook (Revenue, USD Million, 2021 - 2033)
  • Therapeutic
  • Research
  • Diagnostic
  • End Use Outlook (Revenue, USD Million, 2021 - 2033)
  • Pharmaceutical & Biopharmaceutical Companies
  • Diagnostic Companies
  • Others
  • Regional Outlook (Revenue, USD Million, 2021 - 2033)
  • North America
  • U.S.
  • Canada
  • Mexico
  • Europe
  • UK
  • Germany
  • France
  • Italy
  • Spain
  • Denmark
  • Norway
  • Sweden
  • Asia Pacific
  • Japan
  • China
  • India
  • Australia
  • South Korea
  • Thailand
  • Latin America
  • Brazil
  • Argentina
  • Middle East and Africa (MEA)
  • South Africa
  • Saudi Arabia
  • UAE
  • Kuwait
  • Oman
  • Qatar
Please note The report will be delivered in 2-3 business days upon order notification.

Table of Contents

150 Pages
Chapter 1. Methodology and Scope
1.1. Market Segmentation and Scope
1.2. Market Definitions
1.3. Research Methodology
1.4. Information Procurement
1.4.1. Purchased database
1.4.2. GVR’s internal database
1.4.3. Secondary sources
1.4.4. Primary research
1.5. Information or Data Analysis
1.5.1. Data analysis models
1.6. Market Formulation & Validation
1.7. Model Details
1.7.1. Commodity flow analysis (Model 1)
1.7.2. Value chain based analysis (Model 2)
1.7.3. Multivariate Analysis (Model 3)
1.8. List of Secondary Sources
1.9. List of Primary Sources
1.10. Objectives
Chapter 2. Executive Summary
2.1. Market Outlook
2.2. Segment Outlook
2.3. Competitive Landscape Insights
Chapter 3. Oligonucleotide CDMO Market: Variables, Trends, & Scope
3.1. Market Lineage Outlook
3.1.1. Parent Market Outlook
3.1.2. Ancillary Market Outlook
3.2. Oligonucleotide CDMO Market Dynamics
3.2.1. Market Driver Impact Analysis
3.2.2. Market Restraint Analysis
3.2.3. Market Opportunities
3.3. Technological Landscape
3.4. Pricing Model Analysis
3.5. Tariff Impact Analysis
3.6. Supply Chain Analysis
3.7. Market Analysis Tools
3.7.1. Porter’s Five Forces Analysis
3.7.2. PESTEL by SWOT Analysis
Chapter 4. Oligonucleotide CDMO Market: Service Estimates & Trend Analysis
4.1. Segment Dashboard
4.2. Global Oligonucleotide CDMO Market Service Movement Analysis
4.3. Global Oligonucleotide CDMO Market Size & Trend Analysis, by Service, 2021 to 2033 (USD Million)
4.4. Contract Manufacturing
4.4.1. Contract Manufacturing Market Estimates and Forecasts, 2021 - 2033 (USD million)
4.5. Contract Development
4.5.1. Contract Development Market Estimates and Forecasts, 2021 - 2033 (USD Million)
Chapter 5. Oligonucleotide CDMO Market: Type Estimates & Trend Analysis
5.1. Segment Dashboard
5.2. Global Oligonucleotide CDMO Market Type Movement Analysis
5.3. Global Oligonucleotide CDMO Market Size & Trend Analysis, by Type, 2021 to 2033 (USD Million)
5.4. Antisense Oligonucleotides
5.4.1. Antisense Oligonucleotides Market Estimates and Forecasts, 2021 - 2033 (USD Million)
5.5. Small Interfering RNA
5.5.1. Small Interfering RNA Market Estimates and Forecasts, 2021 - 2033 (USD Million)
5.6. Other Oligonucleotides
5.6.1. Other Oligonucleotides Market Estimates and Forecasts, 2021 - 2033 (USD Million)
Chapter 6. Oligonucleotide CDMO Market: Application Estimates & Trend Analysis
6.1. Segment Dashboard
6.2. Global Oligonucleotide CDMO Market Application Movement Analysis
6.3. Global Oligonucleotide CDMO Market Size & Trend Analysis, by Application, 2021 to 2033 (USD Million)
6.4. Therapeutic
6.4.1. Therapeutic Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.5. Research
6.5.1. Research Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.6. Diagnostic
6.6.1. Diagnostic Market Estimates and Forecasts, 2021 - 2033 (USD Million)
Chapter 7. Oligonucleotide CDMO Market: End Use Estimates & Trend Analysis
7.1. Segment Dashboard
7.2. Global Oligonucleotide CDMO Market End Use Movement Analysis
7.3. Global Oligonucleotide CDMO Market Size & Trend Analysis, by End Use, 2021 to 2033 (USD Million)
7.4. Pharmaceutical and Biopharmaceutical Companies
7.4.1. Pharmaceutical and Biopharmaceutical Companies Market Estimates and Forecasts, 2021 - 2033 (USD Million)
7.5. Diagnostic Companies
7.5.1. Diagnostic Companies Market Estimates and Forecasts, 2021 - 2033 (USD Million)
7.6. Others
7.6.1. Others Market Estimates and Forecasts, 2021 - 2033 (USD Million)
Chapter 8. Oligonucleotide CDMO Market: Regional Estimates & Trend Analysis by Product, Service, End Use
8.1. Regional Market Dashboard
8.2. Global Regional Market Snapshot
8.3. Market Size, & Forecasts Trend Analysis, 2021 to 2033:
8.4. North America
8.4.1. North America Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.4.2. U.S.
8.4.2.1. Key Country Dynamics
8.4.2.2. Competitive Scenario
8.4.2.3. Regulatory Framework
8.4.2.4. U.S. Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.4.3. Canada
8.4.3.1. Key Country Dynamics
8.4.3.2. Competitive Scenario
8.4.3.3. Regulatory Framework
8.4.3.4. Canada Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.4.4. Mexico
8.4.4.1. Key Country Dynamics
8.4.4.2. Competitive Scenario
8.4.4.3. Regulatory Framework
8.4.4.4. Mexico Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.5. Europe
8.5.1. Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.5.2. UK
8.5.2.1. Key Country Dynamics
8.5.2.2. Competitive Scenario
8.5.2.3. Regulatory Framework
8.5.2.4. Europe Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.5.3. Germany
8.5.3.1. Key Country Dynamics
8.5.3.2. Competitive Scenario
8.5.3.3. Regulatory Framework
8.5.3.4. Germany Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.5.4. France
8.5.4.1. Key Country Dynamics
8.5.4.2. Competitive Scenario
8.5.4.3. Regulatory Framework
8.5.4.4. France Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.5.5. Italy
8.5.5.1. Key Country Dynamics
8.5.5.2. Competitive Scenario
8.5.5.3. Regulatory Framework
8.5.5.4. Italy Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.5.6. Spain
8.5.6.1. Key Country Dynamics
8.5.6.2. Competitive Scenario
8.5.6.3. Regulatory Framework
8.5.6.4. Spain Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.5.7. Denmark
8.5.7.1. Key Country Dynamics
8.5.7.2. Competitive Scenario
8.5.7.3. Regulatory Framework
8.5.7.4. Denmark Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.5.8. Sweden
8.5.8.1. Key Country Dynamics
8.5.8.2. Competitive Scenario
8.5.8.3. Regulatory Framework
8.5.8.4. Sweden Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.5.9. Norway
8.5.9.1. Key Country Dynamics
8.5.9.2. Competitive Scenario
8.5.9.3. Regulatory Framework
8.5.9.4. Norway Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.6. Asia Pacific
8.6.1. Asia Pacific Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.6.2. Japan
8.6.2.1. Key Country Dynamics
8.6.2.2. Competitive Scenario
8.6.2.3. Regulatory Framework
8.6.2.4. Japan Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.6.3. China
8.6.3.1. Key Country Dynamics
8.6.3.2. Competitive Scenario
8.6.3.3. Regulatory Framework
8.6.3.4. China Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.6.4. India
8.6.4.1. Key Country Dynamics
8.6.4.2. Competitive Scenario
8.6.4.3. Regulatory Framework
8.6.4.4. India Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.6.5. Australia
8.6.5.1. Key Country Dynamics
8.6.5.2. Competitive Scenario
8.6.5.3. Regulatory Framework
8.6.5.4. Australia Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.6.6. South Korea
8.6.6.1. Key Country Dynamics
8.6.6.2. Competitive Scenario
8.6.6.3. Regulatory Framework
8.6.6.4. South Korea Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.6.7. Thailand
8.6.7.1. Key Country Dynamics
8.6.7.2. Competitive Scenario
8.6.7.3. Regulatory Framework
8.6.7.4. Thailand Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.7. Latin America
8.7.1. Latin America Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.7.2. Brazil
8.7.2.1. Key Country Dynamics
8.7.2.2. Competitive Scenario
8.7.2.3. Regulatory Framework
8.7.2.4. Brazil Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.7.3. Argentina
8.7.3.1. Key Country Dynamics
8.7.3.2. Competitive Scenario
8.7.3.3. Regulatory Framework
8.7.3.4. Argentina Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.8. MEA
8.8.1. MEA Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.8.2. South Africa
8.8.2.1. Key Country Dynamics
8.8.2.2. Competitive Scenario
8.8.2.3. Regulatory Framework
8.8.2.4. South Africa Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.8.3. Saudi Arabia
8.8.3.1. Key Country Dynamics
8.8.3.2. Competitive Scenario
8.8.3.3. Regulatory Framework
8.8.3.4. Saudi Arabia Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.8.4. UAE
8.8.4.1. Key Country Dynamics
8.8.4.2. Competitive Scenario
8.8.4.3. Regulatory Framework
8.8.4.4. UAE Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.8.5. Kuwait
8.8.5.1. Key Country Dynamics
8.8.5.2. Competitive Scenario
8.8.5.3. Regulatory Framework
8.8.5.4. Kuwait Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.8.6. Oman
8.8.6.1. Key Country Dynamics
8.8.6.2. Competitive Scenario
8.8.6.3. Regulatory Framework
8.8.6.4. Kuwait Market Estimates and Forecasts, 2021 - 2033 (USD Million)
8.8.7. Qatar
8.8.7.1. Key Country Dynamics
8.8.7.2. Competitive Scenario
8.8.7.3. Regulatory Framework
8.8.7.4. Kuwait Market Estimates and Forecasts, 2021 - 2033 (USD Million)
Chapter 9. Competitive Landscape
9.1. Company Categorization
9.1.1. Market Leaders
9.1.2. Emerging Players
9.2. Oligonucleotide CDMO Market Share Analysis, 2024
9.3. Company Profiles
9.3.1. PolyPeptide Group
9.3.1.1. Company Overview
9.3.1.2. Financial Performance
9.3.1.3. Product/Service Benchmarking
9.3.1.4. Strategic Initiatives
9.3.2. STA Pharmaceutical Co. Ltd.
9.3.2.1. Company Overview
9.3.2.2. Financial Performance
9.3.2.3. Product/Service Benchmarking
9.3.2.4. Strategic Initiatives
9.3.3. Bachem
9.3.3.1. Company Overview
9.3.3.2. Financial Performance
9.3.3.3. Product/Service Benchmarking
9.3.3.4. Strategic Initiatives
9.3.4. Creative Peptides
9.3.4.1. Company Overview
9.3.4.2. Financial Performance
9.3.4.3. Product/Service Benchmarking
9.3.4.4. Strategic Initiatives
9.3.5. Aurigene Pharmaceutical Services Ltd.
9.3.5.1. Company Overview
9.3.5.2. Financial Performance
9.3.5.3. Product/Service Benchmarking
9.3.5.4. Strategic Initiatives
9.3.6. Merck KGaA
9.3.6.1. Company Overview
9.3.6.2. Financial Performance
9.3.6.3. Product/Service Benchmarking
9.3.6.4. Strategic Initiatives
9.3.7. EUROAPI
9.3.7.1. Company Overview
9.3.7.2. Financial Performance
9.3.7.3. Product/Service Benchmarking
9.3.7.4. Strategic Initiatives
9.3.8. Curia Global, Inc.
9.3.8.1. Company Overview
9.3.8.2. Financial Performance
9.3.8.3. Product/Service Benchmarking
9.3.8.4. Strategic Initiatives
9.3.9. CordenPharm
9.3.9.1. Company Overview
9.3.9.2. Financial Performance
9.3.9.3. Product/Service Benchmarking
9.3.9.4. Strategic Initiatives
9.3.10. Sylentis, S.A.
9.3.10.1. Company Overview
9.3.10.2. Financial Performance
9.3.10.3. Product/Service Benchmarking
9.3.10.4. Strategic Initiatives

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