Latent Tuberculosis Infection Detection Market

Latent Tuberculosis Infection Detection Market Summary

The global latent tuberculosis infection detection market size was valued at USD 2.01 billion in 2025 and is projected to reach USD 3.16 billion by 2033, growing at a CAGR of 5.90% from 2026 to 2033. The growth of the market is attributed to the increasing risk of developing active tuberculosis and the growing awareness among people to diagnose tuberculosis infection at an early stage.

Moreover, ongoing government initiatives to combat the threat of tuberculosis and the increasing introduction of novel diagnostic solutions are anticipated to fuel the latent tuberculosis infection (LTBI) detection market growth.

Individuals with LTBI face a lifetime risk of reactivation, which is expected to be around 5% to 15%, with the majority of the population developing TB within the first 5 years. For those with LTBI, untreated HIV infection and no LTBI treatment can lead to a high risk of about 7%-10% per year, emphasizing the importance of timely intervention. In addition, most TB cases in the U.S. result from the progression of LTBI acquired over 2 years ago, highlighting the significance of addressing LTBI to prevent future cases.

The increasing funding for TB diagnosis programs is crucial in the fight against this global disease. The current funding for prevention, diagnosis, and treatment is insufficient to meet the demand, hindering progress in reducing incidence & mortality rates. For instance, an annual investment of USD 22 billion by 2027 was set, with an additional USD 5 billion for research, and only USD 5.8 billion was allocated for TB services, falling short of the required amounts to achieve global targets. Moreover, WHO emphasizes the need for sustained & increased funding to combat TB effectively.

Hence, the U.S. government has significantly increased its funding for TB initiatives, from USD 233 million in 2013 to USD 406 million in 2023. Investments in screening and preventive treatment have shown significant health & economic benefits, with a return on investment of up to USD 39 for every dollar spent. Hence, expanding investments in TB diagnosis programs is essential to improve access to diagnosis, treatment, and prevention to eliminate the TB epidemic by 2033. Moreover, the Global Fund contributes 76% of total international funding for TB, having allocated USD 9.2 billion toward prevention & treatment programs and an extra USD 1.5 billion for TB/HIV initiatives by June 2023. In countries receiving support from the Global Fund, TB-related fatalities have decreased by 36% from 2002 to 2022.

Moreover, the increasing number of elderly individuals worldwide poses a major hurdle in the control of TB within this age group. The rates of TB case detection & incidence are particularly high among older adults, emphasizing the importance of incorporating specific measures in TB response strategies to address their increased risk. In the Western Pacific, where the population is aging rapidly, there has been a notable increase in TB cases among older individuals, propelling the need for customized approaches to diagnosis, treatment, and care for this vulnerable demographic. This is expected to improve the need for the development of effective & efficient diagnostics to meet the rising demand for management among older populations.

However, the regulatory framework for approvals poses major restraints on the growth rate of the pharmaceutical, biotechnology, and medical technology industries. Globally, usage & safety profiles of diagnostic tests vary and are evaluated by health regulatory agencies of each country differently. This makes the approval of novel products slower.

Global Latent Tuberculosis Infection Detection Market Report Segmentation

This report forecasts revenue growth and provides an analysis on the latest trends in each of the sub-segments from 2021 to 2033. For this report, Grand View Research has segmented the latent tuberculosis infection detection market report based on brand, test, application, end use, and region:

• Brand Outlook (Volume, Thousands; Revenue, USD Million, 2021 - 2033)
• QFT-Plus (QuantiFERON-TB Gold Plus)
• Others
• Test Outlook (Volume, Thousands; Revenue, USD Million, 2021 - 2033)
• Tuberculin Skin Test (TST)
• Interferon Gamma Released Assay (IGRAa)
• Application Outlook (Volume, Thousands; Revenue, USD Million, 2021 - 2033)
• Household Contacts with Pulmonary TB
• PLHIV
• Others
• End Use Outlook (Volume, Thousands; Revenue, USD Million, 2021 - 2033)
• Diagnostic Laboratories
• Hospitals/Clinics
• Academic & Research Institutions
• Regional Outlook (Volume, Thousands; Revenue, USD Million, 2021 - 2033)
• North America
• U.S.
• Canada
• Mexico
• Europe
• Germany
• UK
• France
• Italy
• Spain
• Denmark
• Sweden
• Norway
• Belgium
• Netherlands
• Iceland
• Luxembourg
• Finland
• Asia Pacific
• Japan
• China
• India
• Australia
• South Korea
• Thailand
• Singapore
• Bangladesh
• Latin America
• Brazil
• Argentina
• Middle East and Africa (MEA)
• South Africa
• Saudi Arabia
• UAE
• Kuwait

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