Market Size & Trends
The global large and small-scale bioprocessing market size was valued at USD 80.5 billion in 2024 and is expected to grow at a CAGR of 13.8% from 2025 to 2030. Bioprocess engineering has been effectively explored for the development of biopharmaceuticals, and it has provided bio manufacturers and contract manufacturing organizations (CMOs) with lucrative avenues of growth. This, in turn, is expected to attract focused efforts to bolster the market adoption of various bioprocess engineering solutions.
Large Scale Bioprocessing involves the production of biopharmaceuticals and other biological products on a massive scale, typically using large bioreactors and extensive facilities. Whereas, small scale bioprocessing focuses on smaller batches, often utilizing micro-bioreactors and flexible systems for more precise control over production conditions. Both scales are crucial for meeting diverse market demands, from mass-produced vaccines to personalized medicines. The demand for biopharmaceuticals is a significant driver of this market, as these products offer targeted therapies for chronic diseases such as cancer and diabetes. This increasing demand fuels investments in technologies such as advanced incubation systems and filtration devices, ensuring that bioprocessing systems can scale efficiently while maintaining regulatory compliance.
As bioprocessing technologies evolve, manufacturers are adopting innovative solutions to enhance efficiency, reduce costs, and improve product quality. Technological advancements, including single-use technologies and automation, play a pivotal role in driving market growth. These innovations enable more efficient and cost-effective production methods, enhance process control, and minimize contamination risks. Furthermore, the shift towards personalized medicine necessitates scalable bioprocessing solutions that can adapt to smaller batch sizes without compromising quality. This customization trend positions the bioprocessing market for robust growth.
Rising investments in biotechnology research also significantly boost the market. Governments and private sectors are directing substantial funding towards biotechnological innovations, promoting collaborations between academic institutions, research organizations, and industry players. For instance, according to the UK Bio industy Association (BIA), UK biotechnology grant funding is expected to grow in 2025/2026. The Biotech and Medical sector received approximately over USD 160 million for R&D and over USD 50 million for capital investments in equipment. Innovation funding experienced a five-fold is projected to reach over USD 1 billion, focusing on under-funded regions and sectors undergoing digitalization such as healthcare.
The UK government plans to enhance innovation and economic growth via targeted incentives. This surge in funding supports the development of advanced bioprocessing techniques and facilities, driving substantial growth in the coming years. As more resources are allocated towards enhancing bioprocessing infrastructures, the market is poised to expand further, driven by the interplay of technological advancements, increasing demand for biopharmaceuticals, and strategic investments in research and development.
Global Large And Small-scale Bioprocessing Market Report Segmentation
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the global large and small-scale bioprocessing market report based on scale, workflow, product, application, use type, mode, and region:
- Scale Outlook (Revenue, USD Million, 2018 - 2030)
- Industrial Scale (Over 50,000 Litre)
- Small Scale (Less Than 50,000 Litre)
- Workflow Outlook (Revenue, USD Million, 2018 - 2030)
- Downstream Processing
- Fermentation
- Upstream Processing
- Product Outlook (Revenue, USD Million, 2018 - 2030)
- Bioreactors/Fermenters
- Cell Culture Products
- Filtration Assemblies
- Bioreactors Accessories
- Bags & Containers
- Others
- Application Outlook (Revenue, USD Million, 2018 - 2030)
- Biopharmaceuticals
- Speciality Industrial Chemicals
- Environmental Aids
- Use Type Outlook (Revenue, USD Million, 2018 - 2030)
- Multi-Use
- Single-Use
- Mode Outlook (Revenue, USD Million, 2018 - 2030)
- In-house
- Outsourced
- Regional Outlook (Revenue, USD Million, 2018 - 2030)
- North America
Canada
Mexico
- Europe
Germany
France
Italy
Spain
Denmark
Sweden
Norway
- Asia Pacific
China
India
Australia
Thailand
South Korea
- Latin America
Argentina
- Middle East & Africa
Saudi Arabia
UAE
Kuwait
- Chapter 1. Methodology and Scope
- 1.1. Market Segmentation & Scope
- 1.2. Segment Definitions
- 1.2.1. Scale
- 1.2.2. Workflow
- 1.2.3. Product
- 1.2.4. Application
- 1.2.5. Use Type
- 1.2.6. Mode
- 1.3. Estimates and Forecast Timeline
- 1.4. Research Methodology
- 1.5. Information Procurement
- 1.5.1. Purchased Database
- 1.5.2. GVR’s Internal Database
- 1.5.3. Secondary Sources
- 1.5.4. Primary Research
- 1.6. Information Analysis
- 1.6.1. Data Analysis Models
- 1.7. Market Formulation & Data Visualization
- 1.8. Model Details
- 1.8.1. Commodity Flow Analysis
- 1.9. List of Secondary Sources
- 1.10. Objectives
- Chapter 2. Executive Summary
- 2.1. Market Snapshot
- 2.2. Segment Snapshot
- 2.3. Competitive Landscape Snapshot
- Chapter 3. Large and Small-Scale Bioprocessing Market Variables, Trends, & Scope
- 3.1. Market Lineage Outlook
- 3.2. Market Dynamics
- 3.2.1. Market Driver Analysis
- 3.2.2. Market Restraint Analysis
- 3.3. Business Environment Analysis
- 3.3.1. Industry Analysis - Porter’s Five Forces Analysis
- 3.3.1.1. Supplier Power
- 3.3.1.2. Buyer Power
- 3.3.1.3. Substitution Threat
- 3.3.1.4. Threat of New Entrants
- 3.3.1.5. Competitive Rivalry
- 3.3.2. PESTLE Analysis
- Chapter 4. Large and Small-Scale Bioprocessing Market: Scale Business Analysis
- 4.1. Scale Market Share, 2024 & 2030
- 4.2. Scale Segment Dashboard
- 4.3. Market Size & Forecasts and Trend Analysis, by Scale, 2018 to 2030 (USD Million)
- 4.4. Industrial Scale (Over 50,000 Litre)
- 4.4.1. Industrial Scale (Over 50,000 Litre) Market, 2018 - 2030 (USD Million)
- 4.5. Small Scale (Less Than 50,000 Litre)
- 4.5.1. Small Scale (Less Than 50,000 Litre) Market, 2018 - 2030 (USD Million)
- Chapter 5. Large and Small-Scale Bioprocessing Market: Workflow Business Analysis
- 5.1. Workflow Market Share, 2024 & 2030
- 5.2. Workflow Segment Dashboard
- 5.3. Market Size & Forecasts and Trend Analysis, by Workflow, 2018 to 2030 (USD Million)
- 5.4. Downstream Processing
- 5.4.1. Downstream Processing Market, 2018 - 2030 (USD Million)
- 5.5. Fermentation
- 5.5.1. Fermentation Market, 2018 - 2030 (USD Million)
- 5.6. Upstream Processing
- 5.6.1. Upstream Processing Market, 2018 - 2030 (USD Million)
- Chapter 6. Large and Small-Scale Bioprocessing Market: Product Business Analysis
- 6.1. Product Market Share, 2024 & 2030
- 6.2. Product Segment Dashboard
- 6.3. Market Size & Forecasts and Trend Analysis, by Product, 2018 to 2030 (USD Million)
- 6.4. Bioreactors/Fermenters
- 6.4.1. Bioreactors/Fermenters Market, 2018 - 2030 (USD Million)
- 6.5. Cell Culture Products
- 6.5.1. Cell Culture Products Market, 2018 - 2030 (USD Million)
- 6.6. Filtration Assemblies
- 6.6.1. Filtration Assemblies Market, 2018 - 2030 (USD Million)
- 6.7. Bioreactors Accessories
- 6.7.1. Bioreactors Accessories Market, 2018 - 2030 (USD Million)
- 6.8. Bags & Containers
- 6.8.1. Bags & Containers Market, 2018 - 2030 (USD Million)
- 6.9. Other
- 6.9.1. Other Market, 2018 - 2030 (USD Million)
- Chapter 7. Large and Small-Scale Bioprocessing Market: Application Business Analysis
- 7.1. Application Market Share, 2024 & 2030
- 7.2. Application Segment Dashboard
- 7.3. Market Size & Forecasts and Trend Analysis, by Application, 2018 to 2030 (USD Million)
- 7.4. Biopharmaceuticals
- 7.4.1. Biopharmaceuticals Market, 2018 - 2030 (USD Million)
- 7.5. Speciality Industrial Chemicals
- 7.5.1. Speciality Industrial Chemicals Market, 2018 - 2030 (USD Million)
- 7.6. Environmental Aids
- 7.6.1. Environmental Aids Market, 2018 - 2030 (USD Million)
- Chapter 8. Large and Small-Scale Bioprocessing Market: Use Type Business Analysis
- 8.1. Use Type Market Share, 2024 & 2030
- 8.2. Use Type Segment Dashboard
- 8.3. Market Size & Forecasts and Trend Analysis, by Use Type, 2018 to 2030 (USD Million)
- 8.4. Multi-Use
- 8.4.1. Multi-Use Market, 2018 - 2030 (USD Million)
- 8.5. Single-Use
- 8.5.1. Single-Use Market, 2018 - 2030 (USD Million)
- Chapter 9. Large and Small-Scale Bioprocessing Market: Mode Business Analysis
- 9.1. Mode Market Share, 2024 & 2030
- 9.2. Mode Segment Dashboard
- 9.3. Market Size & Forecasts and Trend Analysis, by Mode, 2018 to 2030 (USD Million)
- 9.4. Biopharmaceuticals
- 9.4.1. Biopharmaceuticals Market, 2018 - 2030 (USD Million)
- 9.5. Speciality Industrial Chemicals
- 9.5.1. Speciality Industrial Chemicals Market, 2018 - 2030 (USD Million)
- 9.6. In-House
- 9.6.1. In-House Market, 2018 - 2030 (USD Million)
- 9.7. Outsourced
- 9.7.1. Outsourced Market, 2018 - 2030 (USD Million)
- Chapter 10. Large and Small-Scale Bioprocessing Market: Regional Estimates & Trend Analysis
- 10.1. Regional Market Share Analysis, 2024 & 2030
- 10.2. Regional Market Dashboard
- 10.3. Market Size, & Forecasts Trend Analysis, 2018 to 2030:
- 10.4. North America
- 10.4.1. North America Large and Small-Scale Bioprocessing Market Estimates and Forecasts, By Country, 2018 - 2030 (USD Million)
- 10.4.2. U.S.
- 10.4.2.1. Key Country Dynamics
- 10.4.2.2. Regulatory Framework
- 10.4.2.3. Competitive Insights
- 10.4.2.4. U.S. Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.4.3. Canada
- 10.4.3.1. Key Country Dynamics
- 10.4.3.2. Regulatory Framework
- 10.4.3.3. Competitive Insights
- 10.4.3.4. Canada Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.4.4. Mexico
- 10.4.4.1. Key Country Dynamics
- 10.4.4.2. Regulatory Framework
- 10.4.4.3. Competitive Insights
- 10.4.4.4. Mexico Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.5. Europe
- 10.5.1. Europe Large and Small-Scale Bioprocessing Market Estimates and Forecasts, By Country, 2018 - 2030 (USD Million)
- 10.5.2. Germany
- 10.5.2.1. Key Country Dynamics
- 10.5.2.2. Regulatory Framework
- 10.5.2.3. Competitive Insights
- 10.5.2.4. Germany Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.5.3. UK
- 10.5.3.1. Key Country Dynamics
- 10.5.3.2. Regulatory Framework
- 10.5.3.3. Competitive Insights
- 10.5.3.4. UK Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.5.4. France
- 10.5.4.1. Key Country Dynamics
- 10.5.4.2. Regulatory Framework
- 10.5.4.3. Competitive Insights
- 10.5.4.4. France Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.5.5. Italy
- 10.5.5.1. Key Country Dynamics
- 10.5.5.2. Regulatory Framework
- 10.5.5.3. Competitive Insights
- 10.5.5.4. Italy Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.5.6. Spain
- 10.5.6.1. Key Country Dynamics
- 10.5.6.2. Regulatory Framework
- 10.5.6.3. Competitive Insights
- 10.5.6.4. Spain Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.5.7. Denmark
- 10.5.7.1. Key Country Dynamics
- 10.5.7.2. Regulatory Framework
- 10.5.7.3. Competitive Insights
- 10.5.7.4. Denmark Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.5.8. Sweden
- 10.5.8.1. Key Country Dynamics
- 10.5.8.2. Regulatory Framework
- 10.5.8.3. Competitive Insights
- 10.5.8.4. Sweden Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.5.9. Norway
- 10.5.9.1. Key Country Dynamics
- 10.5.9.2. Regulatory Framework
- 10.5.9.3. Competitive Insights
- 10.5.9.4. Norway Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.6. Asia Pacific
- 10.6.1. Asia Pacific Large and Small-Scale Bioprocessing Market Estimates and Forecasts, By Country, 2018 - 2030 (USD Million)
- 10.6.2. Japan
- 10.6.2.1. Key Country Dynamics
- 10.6.2.2. Regulatory Framework
- 10.6.2.3. Competitive Insights
- 10.6.2.4. Japan Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.6.3. China
- 10.6.3.1. Key Country Dynamics
- 10.6.3.2. Regulatory Framework
- 10.6.3.3. Competitive Insights
- 10.6.3.4. China Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.6.4. India
- 10.6.4.1. Key Country Dynamics
- 10.6.4.2. Regulatory Framework
- 10.6.4.3. Competitive Insights
- 10.6.4.4. India Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.6.5. Australia
- 10.6.5.1. Key Country Dynamics
- 10.6.5.2. Regulatory Framework
- 10.6.5.3. Competitive Insights
- 10.6.5.4. Australia Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.6.6. Thailand
- 10.6.6.1. Key Country Dynamics
- 10.6.6.2. Regulatory Framework
- 10.6.6.3. Competitive Insights
- 10.6.6.4. Thailand Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.6.7. South Korea
- 10.6.7.1. Key Country Dynamics
- 10.6.7.2. Regulatory Framework
- 10.6.7.3. Competitive Insights
- 10.6.7.4. South Korea Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.7. Latin America
- 10.7.1. Latin America Large and Small-Scale Bioprocessing Market Estimates and Forecasts, By Country, 2018 - 2030 (USD Million)
- 10.7.2. Brazil
- 10.7.2.1. Key Country Dynamics
- 10.7.2.2. Regulatory Framework
- 10.7.2.3. Competitive Insights
- 10.7.2.4. Brazil Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.7.3. Argentina
- 10.7.3.1. Key Country Dynamics
- 10.7.3.2. Regulatory Framework
- 10.7.3.3. Competitive Insights
- 10.7.3.4. Argentina Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.8. MEA
- 10.8.1. MEA Large and Small-Scale Bioprocessing Market Estimates and Forecasts, By Country, 2018 - 2030 (USD Million)
- 10.8.2. South Africa
- 10.8.2.1. Key Country Dynamics
- 10.8.2.2. Regulatory Framework
- 10.8.2.3. Competitive Insights
- 10.8.2.4. South Africa Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.8.3. Saudi Arabia
- 10.8.3.1. Key Country Dynamics
- 10.8.3.2. Regulatory Framework
- 10.8.3.3. Competitive Insights
- 10.8.3.4. Saudi Arabia Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.8.4. UAE
- 10.8.4.1. Key Country Dynamics
- 10.8.4.2. Regulatory Framework
- 10.8.4.3. Competitive Insights
- 10.8.4.4. UAE Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 10.8.5. Kuwait
- 10.8.5.1. Key Country Dynamics
- 10.8.5.2. Regulatory Framework
- 10.8.5.3. Competitive Insights
- 10.8.5.4. Kuwait Large and Small-Scale Bioprocessing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- Chapter 11. Competitive Landscape
- 11.1. Participant Overview
- 11.2. Company Market Position Analysis
- 11.3. Company Categorization
- 11.4. Strategy Mapping
- 11.5. Company Profiles/Listing
- 11.5.1. Merck KGaA
- 11.5.1.1. Overview
- 11.5.1.2. Financial Performance
- 11.5.1.3. Product Benchmarking
- 11.5.1.4. Strategic Initiatives
- 11.5.2. Thermo Fisher Scientific, Inc.
- 11.5.2.1. Overview
- 11.5.2.2. Financial Performance
- 11.5.2.3. Product Benchmarking
- 11.5.2.4. Strategic Initiatives
- 11.5.3. GE healthcare
- 11.5.3.1. Overview
- 11.5.3.2. Financial Performance
- 11.5.3.3. Product Benchmarking
- 11.5.3.4. Strategic Initiatives
- 11.5.4. Corning, Inc.
- 11.5.4.1. Overview
- 11.5.4.2. Financial Performance
- 11.5.4.3. Product Benchmarking
- 11.5.4.4. Strategic Initiatives
- 11.5.5. Sartorius AG
- 11.5.5.1. Overview
- 11.5.5.2. Financial Performance
- 11.5.5.3. Product Benchmarking
- 11.5.5.4. Strategic Initiatives
- 11.5.6. CESCO BIOENGINEERING CO., LTD
- 11.5.6.1. Overview
- 11.5.6.2. Financial Performance
- 11.5.6.3. Product Benchmarking
- 11.5.6.4. Strategic Initiatives
- 11.5.7. Bio-Process Group
- 11.5.7.1. Overview
- 11.5.7.2. Financial Performance
- 11.5.7.3. Product Benchmarking
- 11.5.7.4. Strategic Initiatives
- 11.5.8. Bioprocess Control AB
- 11.5.8.1. Overview
- 11.5.8.2. Financial Performance
- 11.5.8.3. Product Benchmarking
- 11.5.8.4. Strategic Initiatives
- 11.5.9. Eppendorf AG
- 11.5.9.1. Overview
- 11.5.9.2. Financial Performance
- 11.5.9.3. Product Benchmarking
- 11.5.9.4. Strategic Initiatives
- 11.5.10. Applikon Biotechnology
- 11.5.10.1. Overview
- 11.5.10.2. Financial Performance
- 11.5.10.3. Product Benchmarking
- 11.5.10.4. Strategic Initiatives
- 11.5.11. Lonza
- 11.5.11.1. Overview
- 11.5.11.2. Financial Performance
- 11.5.11.3. Product Benchmarking
- 11.5.11.4. Strategic Initiatives
- 11.5.12. PBS Biotech, Inc
- 11.5.12.1. Overview
- 11.5.12.2. Financial Performance
- 11.5.12.3. Product Benchmarking
- 11.5.12.4. Strategic Initiatives
- 11.5.13. Finesse
- 11.5.13.1. Overview
- 11.5.13.2. Financial Performance
- 11.5.13.3. Product Benchmarking
- 11.5.13.4. Strategic Initiatives
- 11.5.14. Meissner Filtration Products, Inc.
- 11.5.14.1. Overview
- 11.5.14.2. Financial Performance
- 11.5.14.3. Product Benchmarking
- 11.5.14.4. Strategic Initiatives
- 11.5.15. CellGenix GmbH
- 11.5.15.1. Overview
- 11.5.15.2. Financial Performance
- 11.5.15.3. Product Benchmarking
- 11.5.15.4. Strategic Initiatives
- 11.5.16. Boehringer Ingelheim
- 11.5.16.1. Overview
- 11.5.16.2. Financial Performance
- 11.5.16.3. Product Benchmarking
- 11.5.16.4. Strategic Initiatives
- 11.5.17. Samsung BioLogics
- 11.5.17.1. Overview
- 11.5.17.2. Financial Performance
- 11.5.17.3. Product Benchmarking
- 11.5.17.4. Strategic Initiatives
- 11.5.18. Patheon
- 11.5.18.1. Overview
- 11.5.18.2. Financial Performance
- 11.5.18.3. Product Benchmarking
- 11.5.18.4. Strategic Initiatives
- 11.5.19. CMC Biologics
- 11.5.19.1. Overview
- 11.5.19.2. Financial Performance
- 11.5.19.3. Product Benchmarking
- 11.5.19.4. Strategic Initiatives
- 11.5.20. Binex Co., Ltd
- 11.5.20.1. Overview
- 11.5.20.2. Financial Performance
- 11.5.20.3. Product Benchmarking
- 11.5.20.4. Strategic Initiatives
- 11.5.21. Rentschler Biotechnology GmbH
- 11.5.21.1. Overview
- 11.5.21.2. Financial Performance
- 11.5.21.3. Product Benchmarking
- 11.5.21.4. Strategic Initiatives
- 11.5.22. TOYOBA CO., LTD.
- 11.5.22.1. Overview
- 11.5.22.2. Financial Performance
- 11.5.22.3. Product Benchmarking
- 11.5.22.4. Strategic Initiatives
- 11.5.23. Inno Biologics Sdn Bhd
- 11.5.23.1. Overview
- 11.5.23.2. Financial Performance
- 11.5.23.3. Product Benchmarking
- 11.5.23.4. Strategic Initiatives
- 11.5.24. F. Hoffmann-La Roche Ltd
- 11.5.24.1. Overview
- 11.5.24.2. Financial Performance
- 11.5.24.3. Product Benchmarking
- 11.5.24.4. Strategic Initiatives
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