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Hepatitis Therapeutics Market Size, Share & Trends Analysis Report By Disease (Hepatitis A, Hepatitis B, Hepatitis C), By Distribution Channel (Hospital Pharmacies, Drug Stores & Retail Pharmacies), By Region, And Segment Forecasts, 2025 - 2033

Publisher Grand View Research
Published Sep 30, 2025
Length 150 Pages
SKU # GV20471184

Description

Hepatitis Therapeutics Market Summary

The global hepatitis therapeutics market size was estimated at USD 16.80 billion in 2024 and is projected to reach USD 23.62 billion by 2033, growing at a CAGR of 3.9% from 2025 to 2033. The global market is expanding as the prevalence of hepatitis B and C infections continues to pose a significant health challenge.

Improved screening and rising clinical awareness have accelerated early diagnosis, supporting timely treatment initiation. Demand for antivirals, direct-acting antivirals, and immunomodulators remains strong, forming the backbone of current therapies. For instance, the Hepatitis B Foundation reported FDA approval of seven medications for chronic hepatitis B, including five oral antivirals: Viread, Vemlidy, Baraclude, Epivir-HBV, and Hepsera, along with two injectable immune modulators: Pegasys and Intron A. The foundation emphasized that treatment decisions should consider liver disease activity and cirrhosis, with regular specialist monitoring recommended. Rising adoption of curative hepatitis C therapies further strengthens growth prospects.

Another key driver is the rise in liver-related complications associated with untreated hepatitis infections, such as cirrhosis and hepatocellular carcinoma, which is pushing demand for advanced therapeutic approaches. The increasing burden of comorbid conditions in aging populations has heightened reliance on antiviral regimens with proven efficacy and safety. Pharmaceutical companies are actively investing in clinical research to address these needs through therapies with higher cure rates and improved tolerability. For instance, in August 2025, Applied Clinical Trials Online reported that Aligos Therapeutics had initiated dosing in its Phase II B-SUPREME trial of ALG-000184, a first-in-class oral capsid assembly modulator, in approximately 200 treatment-naïve adults with chronic hepatitis B, including both HBeAg-positive and HBeAg-negative patients. The randomized, double-masked study was designed to compare ALG-000184 monotherapy with tenofovir disoproxil fumarate over 48 weeks, with primary endpoints focusing on HBV DNA suppression and secondary outcomes assessing safety, pharmacokinetics, and antigen reductions. Interim findings were expected in 2026, and topline results in 2027, while earlier Phase I data had already demonstrated sustained antiviral activity, favorable safety, and no new safety signals, reinforcing the momentum of clinical innovation in hepatitis therapeutics.

The emergence of cell-based immunotherapies is driving growth in the hepatitis therapeutics market, particularly for patients with advanced liver complications from chronic infections. For instance, in May 2025, OncLive reported that SCG101, an autologous HBV-specific T-cell therapy, delivered antiviral and antitumor activity in advanced HBV-related hepatocellular carcinoma. In a Phase I trial, 94% of patients achieved notable HBsAg reductions within 28 days, with sustained control for up to one year, while 23.5% achieved complete HBsAg loss. Tumor responses were observed in 47% of patients, and median overall survival had not been reached. Safety remained manageable, with transient ALT elevations and cytokine release syndrome being the most common events. These outcomes underscore the role of innovative immunotherapies in addressing unmet needs and strengthening market expansion.

Global Hepatitis Therapeutics Market Report Segmentation

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Grand View Research has segmented the global hepatitis therapeutics market report based on disease, distribution channel, and region:
  • Disease Outlook (Revenue, USD Million, 2021 - 2033)
  • Hepatitis A
  • Hepatitis B
  • Hepatitis C
  • Others
  • Distribution Channel Outlook (Revenue, USD Million, 2021 - 2033)
  • Hospital Pharmacies
  • Drug Stores and Retail Pharmacies
  • Others
  • Regional Outlook (Revenue, USD Million, 2021 - 2033)
  • North America
  • U.S.
  • Canada
  • Mexico
  • Europe
  • UK
  • Germany
  • France
  • Italy
  • Spain
  • Denmark
  • Sweden
  • Norway
  • Asia Pacific
  • Japan
  • China
  • India
  • Australia
  • South Korea
  • Thailand
  • Latin America
  • Brazil
  • Argentina
  • Middle East & Africa
  • South Africa
  • Saudi Arabia
  • UAE
  • Kuwait
Please note The report will be delivered in 2-3 business days upon order notification.

Table of Contents

150 Pages
Chapter 1. Methodology and Scope
1.1. Market Segmentation & Scope
1.2. Segment Definitions
1.2.1. Disease
1.2.2. Distribution Channel
1.3. Estimates and Forecast Timeline
1.4. Research Methodology
1.5. Information Procurement
1.5.1. Purchased Database
1.5.2. GVR’s Internal Database
1.5.3. Secondary Sources
1.5.4. Primary Research
1.6. Information Analysis
1.6.1. Data Analysis Models
1.7. Market Formulation & Data Visualization
1.8. Model Details
1.8.1. Commodity Flow Analysis
1.9. List of Secondary Sources
1.10. Objectives
Chapter 2. Executive Summary
2.1. Market Snapshot
2.2. Segment Snapshot
2.3. Competitive Landscape Snapshot
Chapter 3. Hepatitis Therapeutics Market Variables, Trends, & Scope
3.1. Market Lineage Outlook
3.2. Market Dynamics
3.2.1. Market Driver Analysis
3.2.2. Market Restraint Analysis
3.3. Business Environment Analysis
3.3.1. Industry Analysis - Porter’s Five Forces Analysis
3.3.1.1. Supplier Power
3.3.1.2. Buyer Power
3.3.1.3. Substitution Threat
3.3.1.4. Threat of New Entrants
3.3.1.5. Competitive Rivalry
3.3.2. PESTLE Analysis
3.3.3. Pipeline Analysis
3.3.4. Patent Expiry Analysis
3.3.5. Pricing Analysis
Chapter 4. Hepatitis Therapeutics Market: Disease Business Analysis
4.1. Disease Market Share, 2024 & 2033
4.2. Disease Segment Dashboard
4.3. Market Size & Forecasts and Trend Analysis, by Disease, 2021 to 2033 (USD Million)
4.4. Hepatitis A
4.4.1. Hepatitis A Market, 2021 - 2033 (USD Million)
4.5. Hepatitis B
4.5.1. Hepatitis B Market, 2021 - 2033 (USD Million)
4.6. Hepatitis C
4.6.1. Hepatitis C Market, 2021 - 2033 (USD Million)
4.7. Others
4.7.1. Others Market, 2021 - 2033 (USD Million)
Chapter 5. Hepatitis Therapeutics Market: Distribution Channel Business Analysis
5.1. Distribution Channel Market Share, 2024 & 2033
5.2. Distribution Channel Segment Dashboard
5.3. Market Size & Forecasts and Trend Analysis, by distribution channel, 2021 to 2033 (USD Million)
5.4. Hospital Pharmacies
5.4.1. Hospital Pharmacies Market, 2021 - 2033 (USD Million)
5.5. Drug Stores and Retail Pharmacies
5.5.1. Drug Stores and Retail Pharmacies Market, 2021 - 2033 (USD Million)
5.6. Others
5.6.1. Others Market, 2021 - 2033 (USD Million)
Chapter 6. Hepatitis Therapeutics Market: Regional Estimates & Trend Analysis
6.1. Regional Market Share Analysis, 2024 & 2033
6.2. Regional Market Dashboard
6.3. Market Size & Forecasts Trend Analysis, 2021 to 2033:
6.4. North America
6.4.1. North America Hepatitis Therapeutics Market Estimates and Forecasts, By Country, 2021 - 2033 (USD Million)
6.4.2. U.S.
6.4.2.1. Key Country Dynamics
6.4.2.2. Type Disease Prevalence
6.4.2.3. Regulatory Framework
6.4.2.4. Reimbursement Framework
6.4.2.5. U.S. Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.4.3. Canada
6.4.3.1. Key Country Dynamics
6.4.3.2. Type Disease Prevalence
6.4.3.3. Regulatory Framework
6.4.3.4. Reimbursement Framework
6.4.3.5. U.S. Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.4.4. Mexico
6.4.4.1. Key Country Dynamics
6.4.4.2. Type Disease Prevalence
6.4.4.3. Regulatory Framework
6.4.4.4. Reimbursement Framework
6.4.4.5. Mexico Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.5. Europe
6.5.1. Europe Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.5.2. UK
6.5.2.1. Key Country Dynamics
6.5.2.2. Type Disease Prevalence
6.5.2.3. Regulatory Framework
6.5.2.4. Reimbursement Framework
6.5.2.5. Uk Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.5.3. Germany
6.5.3.1. Key Country Dynamics
6.5.3.2. Type Disease Prevalence
6.5.3.3. Regulatory Framework
6.5.3.4. Reimbursement Framework
6.5.3.5. Germany Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.5.4. France
6.5.4.1. Key Country Dynamics
6.5.4.2. Type Disease Prevalence
6.5.4.3. Regulatory Framework
6.5.4.4. Reimbursement Framework
6.5.4.5. France Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.5.5. Italy
6.5.5.1. Key Country Dynamics
6.5.5.2. Type Disease Prevalence
6.5.5.3. Regulatory Framework
6.5.5.4. Reimbursement Framework
6.5.5.5. Italy Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.5.6. Spain
6.5.6.1. Key Country Dynamics
6.5.6.2. Type Disease Prevalence
6.5.6.3. Regulatory Framework
6.5.6.4. Reimbursement Framework
6.5.6.5. Spain Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.5.7. Denmark
6.5.7.1. Key Country Dynamics
6.5.7.2. Type Disease Prevalence
6.5.7.3. Regulatory Framework
6.5.7.4. Reimbursement Framework
6.5.7.5. Denmark Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.5.8. Sweden
6.5.8.1. Key Country Dynamics
6.5.8.2. Type Disease Prevalence
6.5.8.3. Regulatory Framework
6.5.8.4. Reimbursement Framework
6.5.8.5. Sweden Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.5.9. Norway
6.5.9.1. Key Country Dynamics
6.5.9.2. Type Disease Prevalence
6.5.9.3. Regulatory Framework
6.5.9.4. Reimbursement Framework
6.5.9.5. Norway Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.6. Asia Pacific
6.6.1. Asia Pacific Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.6.2. Japan
6.6.2.1. Key Country Dynamics
6.6.2.2. Type Disease Prevalence
6.6.2.3. Regulatory Framework
6.6.2.4. Reimbursement Framework
6.6.2.5. Japan Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.6.3. China
6.6.3.1. Key Country Dynamics
6.6.3.2. Type Disease Prevalence
6.6.3.3. Regulatory Framework
6.6.3.4. Reimbursement Framework
6.6.3.5. China Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.6.4. India
6.6.4.1. Key Country Dynamics
6.6.4.2. Type Disease Prevalence
6.6.4.3. Regulatory Framework
6.6.4.4. Reimbursement Framework
6.6.4.5. India Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.6.5. Australia
6.6.5.1. Key Country Dynamics
6.6.5.2. Type Disease Prevalence
6.6.5.3. Regulatory Framework
6.6.5.4. Reimbursement Framework
6.6.5.5. Australia Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.6.6. South Korea
6.6.6.1. Key Country Dynamics
6.6.6.2. Type Disease Prevalence
6.6.6.3. Regulatory Framework
6.6.6.4. Reimbursement Framework
6.6.6.5. South Korea Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.6.7. Thailand
6.6.7.1. Key Country Dynamics
6.6.7.2. Type Disease Prevalence
6.6.7.3. Regulatory Framework
6.6.7.4. Reimbursement Framework
6.6.7.5. Thailand Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.7. Latin America
6.7.1. Latin America Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.7.2. Brazil
6.7.2.1. Key Country Dynamics
6.7.2.2. Type Disease Prevalence
6.7.2.3. Regulatory Framework
6.7.2.4. Reimbursement Framework
6.7.2.5. Japan Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.7.3. Argentina
6.7.3.1. Key Country Dynamics
6.7.3.2. Type Disease Prevalence
6.7.3.3. Regulatory Framework
6.7.3.4. Reimbursement Framework
6.7.3.5. China Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.8. Middle East and Africa
6.8.1. Middle East and Africa Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.8.2. South Africa
6.8.2.1. Key Country Dynamics
6.8.2.2. Type Disease Prevalence
6.8.2.3. Regulatory Framework
6.8.2.4. Reimbursement Framework
6.8.2.5. South Africa Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.8.3. Saudi Arabia
6.8.3.1. Key Country Dynamics
6.8.3.2. Type Disease Prevalence
6.8.3.3. Regulatory Framework
6.8.3.4. Reimbursement Framework
6.8.3.5. Saudi Arabia Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.8.4. UAE
6.8.4.1. Key Country Dynamics
6.8.4.2. Type Disease Prevalence
6.8.4.3. Regulatory Framework
6.8.4.4. Reimbursement Framework
6.8.4.5. UAE Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
6.8.5. Kuwait
6.8.5.1. Key Country Dynamics
6.8.5.2. Type Disease Prevalence
6.8.5.3. Regulatory Framework
6.8.5.4. Reimbursement Framework
6.8.5.5. Kuwait Hepatitis Therapeutics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
Chapter 7. Competitive Landscape
7.1. Participant Overview
7.2. Company Market Position Analysis
7.3. Company Categorization
7.4. Strategy Mapping
7.5. Company Profiles/Listing
7.5.1. Teva Pharmaceutical Industries Ltd.
7.5.1.1. Overview
7.5.1.2. Financial Performance
7.5.1.3. Disease Benchmarking
7.5.1.4. Strategic Initiatives
7.5.2. Bristol-Myers Squibb Company
7.5.2.1. Overview
7.5.2.2. Financial Performance
7.5.2.3. Disease Benchmarking
7.5.2.4. Strategic Initiatives
7.5.3. F. Hoffmann-La Roche Ltd
7.5.3.1. Overview
7.5.3.2. Financial Performance
7.5.3.3. Disease Benchmarking
7.5.3.4. Strategic Initiatives
7.5.4. Zydus Group
7.5.4.1. Overview
7.5.4.2. Financial Performance
7.5.4.3. Disease Benchmarking
7.5.4.4. Strategic Initiatives
7.5.5. GSK plc.
7.5.5.1. Overview
7.5.5.2. Financial Performance
7.5.5.3. Disease Benchmarking
7.5.5.4. Strategic Initiatives
7.5.6. AbbVie Inc.
7.5.6.1. Overview
7.5.6.2. Financial Performance
7.5.6.3. Disease Benchmarking
7.5.6.4. Strategic Initiatives
7.5.7. Gilead Sciences, Inc.
7.5.7.1. Overview
7.5.7.2. Financial Performance
7.5.7.3. Disease Benchmarking
7.5.7.4. Strategic Initiatives
7.5.8. Merck & Co., Inc.
7.5.8.1. Overview
7.5.8.2. Financial Performance
7.5.8.3. Disease Benchmarking
7.5.8.4. Strategic Initiatives
7.5.9. Lupin
7.5.9.1. Overview
7.5.9.2. Financial Performance
7.5.9.3. Disease Benchmarking
7.5.9.4. Strategic Initiatives
7.5.10. Cipla
7.5.10.1. Overview
7.5.10.2. Financial Performance
7.5.10.3. Disease Benchmarking
7.5.10.4. Strategic Initiatives 

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