Global Size Exclusion Chromatography (SEC) HPLC Column Supply, Demand and Key Producers, 2026-2032
Description
The global Size Exclusion Chromatography (SEC) HPLC Column market size is expected to reach $ 220 million by 2032, rising at a market growth of 6.1% CAGR during the forecast period (2026-2032).
Size exclusion chromatography (SEC) is a major mode of HPLC that employs porous particles in the column to separate molecules by virtue of their size in solution. SEC is generally used to separate biological molecules, to determine molecular weight distributions of proteins and peptides, as well as to separate a long list of water soluble polymers used in a wide range of industries.
Market Drivers for Size Exclusion Chromatography (SEC) HPLC Columns
The Size Exclusion Chromatography (SEC) HPLC column market is primarily driven by the increasing demand for accurate and reliable analysis of large biomolecules, particularly proteins, nucleic acids, and polymers, in a variety of industries, including pharmaceuticals, biotechnology, and research. SEC HPLC columns are essential for characterizing biomolecules, determining molecular weight, and assessing purity, which makes them indispensable in the biopharmaceutical industry for drug development, production, and quality control. The growing focus on biologic drugs, including monoclonal antibodies, therapeutic proteins, and gene therapies, is fueling the demand for SEC columns to ensure the safety, efficacy, and regulatory compliance of these complex products. Additionally, advancements in SEC column technology, such as improvements in column packing materials, higher resolution, and faster separation times, are driving the adoption of these columns in research laboratories and manufacturing settings. The expansion of proteomics and genomics research is also contributing to the increased need for SEC columns to analyze large biological molecules with high precision.
Challenges in the SEC HPLC Column Market
Despite the strong demand, the SEC HPLC column market faces several challenges. One of the primary obstacles is the high cost associated with high-quality SEC columns, particularly those designed for ultra-high-performance liquid chromatography (UHPLC), which can be a barrier for small to mid-sized laboratories or emerging biotech firms with limited budgets. Additionally, while SEC is a powerful tool for size-based separation, it has limitations in resolving complex mixtures of closely related biomolecules, such as protein isoforms or small differences in molecular size, which can affect the accuracy of analyses. This often necessitates the use of complementary techniques, increasing the overall cost and complexity of experiments. Furthermore, column longevity and maintenance are also issues, as SEC columns may suffer from fouling or degradation over time, especially when used for highly viscous or complex samples. Regular maintenance, recalibration, and the need for more advanced column materials to enhance durability add to operational costs. Lastly, regulatory pressures in the pharmaceutical industry demand consistent performance and reproducibility, which places additional strain on manufacturers to meet strict quality standards for SEC columns.
Global key players of Size Exclusion Chromatography (SEC) HPLC Column include Agilent Technologies, Waters Corporation, Shimadzu, Tosoh Corporation, Thermo Fisher Scientific and Danaher, etc. Top two players occupy for a share about 40%.
This report studies the global Size Exclusion Chromatography (SEC) HPLC Column production, demand, key manufacturers, and key regions.
This report is a detailed and comprehensive analysis of the world market for Size Exclusion Chromatography (SEC) HPLC Column and provides market size (US$ million) and Year-over-Year (YoY) Growth, considering 2025 as the base year. This report explores demand trends and competition, as well as details the characteristics of Size Exclusion Chromatography (SEC) HPLC Column that contribute to its increasing demand across many markets.
Highlights and key features of the study
Global Size Exclusion Chromatography (SEC) HPLC Column total production and demand, 2021-2032, (K Units)
Global Size Exclusion Chromatography (SEC) HPLC Column total production value, 2021-2032, (USD Million)
Global Size Exclusion Chromatography (SEC) HPLC Column production by region & country, production, value, CAGR, 2021-2032, (USD Million) & (K Units), (based on production site)
Global Size Exclusion Chromatography (SEC) HPLC Column consumption by region & country, CAGR, 2021-2032 & (K Units)
U.S. VS China: Size Exclusion Chromatography (SEC) HPLC Column domestic production, consumption, key domestic manufacturers and share
Global Size Exclusion Chromatography (SEC) HPLC Column production by manufacturer, production, price, value and market share 2021-2026, (USD Million) & (K Units)
Global Size Exclusion Chromatography (SEC) HPLC Column production by ID, production, value, CAGR, 2021-2032, (USD Million) & (K Units)
Global Size Exclusion Chromatography (SEC) HPLC Column production by Application, production, value, CAGR, 2021-2032, (USD Million) & (K Units)
This report profiles key players in the global Size Exclusion Chromatography (SEC) HPLC Column market based on the following parameters - company overview, production, value, price, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include Agilent Technologies, Waters Corporation, Shimadzu, Tosoh Corporation, Thermo Fisher Scientific, Danaher, Bio-Rad, Merck, Malvern Instruments, Sepax Technologies, etc.
This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.
Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the World Size Exclusion Chromatography (SEC) HPLC Column market
Detailed Segmentation:
Each section contains quantitative market data including market by value (US$ Millions), volume (production, consumption) & (K Units) and average price (USD/Unit) by manufacturer, by ID, and by Application. Data is given for the years 2021-2032 by year with 2025 as the base year, 2026 as the estimate year, and 2027-2032 as the forecast year.
Global Size Exclusion Chromatography (SEC) HPLC Column Market, By Region:
United States
China
Europe
Japan
South Korea
ASEAN
India
Rest of World
Global Size Exclusion Chromatography (SEC) HPLC Column Market, Segmentation by ID:
ID Below 4.6mm
ID 4.6-7.8mm
ID Above 7.8mm
Global Size Exclusion Chromatography (SEC) HPLC Column Market, Segmentation by Application:
Pharmaceutical and Biotech Company
Academic & Research Institutions
Others
Companies Profiled:
Agilent Technologies
Waters Corporation
Shimadzu
Tosoh Corporation
Thermo Fisher Scientific
Danaher
Bio-Rad
Merck
Malvern Instruments
Sepax Technologies
Key Questions Answered:
1. How big is the global Size Exclusion Chromatography (SEC) HPLC Column market?
2. What is the demand of the global Size Exclusion Chromatography (SEC) HPLC Column market?
3. What is the year over year growth of the global Size Exclusion Chromatography (SEC) HPLC Column market?
4. What is the production and production value of the global Size Exclusion Chromatography (SEC) HPLC Column market?
5. Who are the key producers in the global Size Exclusion Chromatography (SEC) HPLC Column market?
6. What are the growth factors driving the market demand?
Size exclusion chromatography (SEC) is a major mode of HPLC that employs porous particles in the column to separate molecules by virtue of their size in solution. SEC is generally used to separate biological molecules, to determine molecular weight distributions of proteins and peptides, as well as to separate a long list of water soluble polymers used in a wide range of industries.
Market Drivers for Size Exclusion Chromatography (SEC) HPLC Columns
The Size Exclusion Chromatography (SEC) HPLC column market is primarily driven by the increasing demand for accurate and reliable analysis of large biomolecules, particularly proteins, nucleic acids, and polymers, in a variety of industries, including pharmaceuticals, biotechnology, and research. SEC HPLC columns are essential for characterizing biomolecules, determining molecular weight, and assessing purity, which makes them indispensable in the biopharmaceutical industry for drug development, production, and quality control. The growing focus on biologic drugs, including monoclonal antibodies, therapeutic proteins, and gene therapies, is fueling the demand for SEC columns to ensure the safety, efficacy, and regulatory compliance of these complex products. Additionally, advancements in SEC column technology, such as improvements in column packing materials, higher resolution, and faster separation times, are driving the adoption of these columns in research laboratories and manufacturing settings. The expansion of proteomics and genomics research is also contributing to the increased need for SEC columns to analyze large biological molecules with high precision.
Challenges in the SEC HPLC Column Market
Despite the strong demand, the SEC HPLC column market faces several challenges. One of the primary obstacles is the high cost associated with high-quality SEC columns, particularly those designed for ultra-high-performance liquid chromatography (UHPLC), which can be a barrier for small to mid-sized laboratories or emerging biotech firms with limited budgets. Additionally, while SEC is a powerful tool for size-based separation, it has limitations in resolving complex mixtures of closely related biomolecules, such as protein isoforms or small differences in molecular size, which can affect the accuracy of analyses. This often necessitates the use of complementary techniques, increasing the overall cost and complexity of experiments. Furthermore, column longevity and maintenance are also issues, as SEC columns may suffer from fouling or degradation over time, especially when used for highly viscous or complex samples. Regular maintenance, recalibration, and the need for more advanced column materials to enhance durability add to operational costs. Lastly, regulatory pressures in the pharmaceutical industry demand consistent performance and reproducibility, which places additional strain on manufacturers to meet strict quality standards for SEC columns.
Global key players of Size Exclusion Chromatography (SEC) HPLC Column include Agilent Technologies, Waters Corporation, Shimadzu, Tosoh Corporation, Thermo Fisher Scientific and Danaher, etc. Top two players occupy for a share about 40%.
This report studies the global Size Exclusion Chromatography (SEC) HPLC Column production, demand, key manufacturers, and key regions.
This report is a detailed and comprehensive analysis of the world market for Size Exclusion Chromatography (SEC) HPLC Column and provides market size (US$ million) and Year-over-Year (YoY) Growth, considering 2025 as the base year. This report explores demand trends and competition, as well as details the characteristics of Size Exclusion Chromatography (SEC) HPLC Column that contribute to its increasing demand across many markets.
Highlights and key features of the study
Global Size Exclusion Chromatography (SEC) HPLC Column total production and demand, 2021-2032, (K Units)
Global Size Exclusion Chromatography (SEC) HPLC Column total production value, 2021-2032, (USD Million)
Global Size Exclusion Chromatography (SEC) HPLC Column production by region & country, production, value, CAGR, 2021-2032, (USD Million) & (K Units), (based on production site)
Global Size Exclusion Chromatography (SEC) HPLC Column consumption by region & country, CAGR, 2021-2032 & (K Units)
U.S. VS China: Size Exclusion Chromatography (SEC) HPLC Column domestic production, consumption, key domestic manufacturers and share
Global Size Exclusion Chromatography (SEC) HPLC Column production by manufacturer, production, price, value and market share 2021-2026, (USD Million) & (K Units)
Global Size Exclusion Chromatography (SEC) HPLC Column production by ID, production, value, CAGR, 2021-2032, (USD Million) & (K Units)
Global Size Exclusion Chromatography (SEC) HPLC Column production by Application, production, value, CAGR, 2021-2032, (USD Million) & (K Units)
This report profiles key players in the global Size Exclusion Chromatography (SEC) HPLC Column market based on the following parameters - company overview, production, value, price, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include Agilent Technologies, Waters Corporation, Shimadzu, Tosoh Corporation, Thermo Fisher Scientific, Danaher, Bio-Rad, Merck, Malvern Instruments, Sepax Technologies, etc.
This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.
Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the World Size Exclusion Chromatography (SEC) HPLC Column market
Detailed Segmentation:
Each section contains quantitative market data including market by value (US$ Millions), volume (production, consumption) & (K Units) and average price (USD/Unit) by manufacturer, by ID, and by Application. Data is given for the years 2021-2032 by year with 2025 as the base year, 2026 as the estimate year, and 2027-2032 as the forecast year.
Global Size Exclusion Chromatography (SEC) HPLC Column Market, By Region:
United States
China
Europe
Japan
South Korea
ASEAN
India
Rest of World
Global Size Exclusion Chromatography (SEC) HPLC Column Market, Segmentation by ID:
ID Below 4.6mm
ID 4.6-7.8mm
ID Above 7.8mm
Global Size Exclusion Chromatography (SEC) HPLC Column Market, Segmentation by Application:
Pharmaceutical and Biotech Company
Academic & Research Institutions
Others
Companies Profiled:
Agilent Technologies
Waters Corporation
Shimadzu
Tosoh Corporation
Thermo Fisher Scientific
Danaher
Bio-Rad
Merck
Malvern Instruments
Sepax Technologies
Key Questions Answered:
1. How big is the global Size Exclusion Chromatography (SEC) HPLC Column market?
2. What is the demand of the global Size Exclusion Chromatography (SEC) HPLC Column market?
3. What is the year over year growth of the global Size Exclusion Chromatography (SEC) HPLC Column market?
4. What is the production and production value of the global Size Exclusion Chromatography (SEC) HPLC Column market?
5. Who are the key producers in the global Size Exclusion Chromatography (SEC) HPLC Column market?
6. What are the growth factors driving the market demand?
Table of Contents
111 Pages
- 1 Supply Summary
- 2 Demand Summary
- 3 World Manufacturers Competitive Analysis
- 4 United States VS China VS Rest of the World
- 5 Market Analysis by ID
- 6 Market Analysis by Application
- 7 Company Profiles
- 8 Industry Chain Analysis
- 9 Research Findings and Conclusion
- 10 Appendix
Pricing
Currency Rates
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