Global Rolling Circle Amplification Market 2025 by Manufacturers, Regions, Type and Application, Forecast to 2031

According to our (Global Info Research) latest study, the global Rolling Circle Amplification market size was valued at US$ 1034 million in 2024 and is forecast to a readjusted size of USD 1995 million by 2031 with a CAGR of 10.0% during review period.

Rolling circle amplification (RCA) is an isothermal enzymatic process that uses a circular DNA template and special DNA or RNA polymerases to amplify a short DNA or RNA primer to form a long single stranded DNA or RNA. The RCA product is a concatemer composed of tens to hundreds of tandem repeats that complement the circular template. The DNA amplification technique"s power, simplicity, and versatility have made it an appealing tool for biomedical research and nanobiotechnology. RCA has traditionally been used to create sensitive diagnostic methods for a wide range of targets such as nucleic acids (DNA, RNA), small molecules, proteins, and cells. RCA has also received a great deal of attention in the fields of nanotechnology and nanobiotechnology.

Immuno-RCA uses antibodies conjugated to oligonucleotides to detect individual proteins. A circular DNA template can be hybridized to it and then amplified by the enzyme phi29 polymerase using antibody-conjugated oligonucleotides as primers. This will result in the formation of RCP covalently linked to the antibody. Two antibodies are conjugated to two different oligonucleotides in PLA (proximity probes). Proximity probes are assumed to bind to their very close targets. In this case, they will serve as hybridization/ligation templates for two other oligonucleotides, resulting in a circular DNA template that can be amplified using one of the proximity probes as an RCA primer. The increasing application of rolling circle amplification has resulted in high growth of the rolling circle amplification market.

This report is a detailed and comprehensive analysis for global Rolling Circle Amplification market. Both quantitative and qualitative analyses are presented by manufacturers, by region & country, by Type and by Application. As the market is constantly changing, this report explores the competition, supply and demand trends, as well as key factors that contribute to its changing demands across many markets. Company profiles and product examples of selected competitors, along with market share estimates of some of the selected leaders for the year 2025, are provided.

Key Features:

Global Rolling Circle Amplification market size and forecasts, in consumption value ($ Million), sales quantity (K Units), and average selling prices (US$/Unit), 2020-2031

Global Rolling Circle Amplification market size and forecasts by region and country, in consumption value ($ Million), sales quantity (K Units), and average selling prices (US$/Unit), 2020-2031

Global Rolling Circle Amplification market size and forecasts, by Type and by Application, in consumption value ($ Million), sales quantity (K Units), and average selling prices (US$/Unit), 2020-2031

Global Rolling Circle Amplification market shares of main players, shipments in revenue ($ Million), sales quantity (K Units), and ASP (US$/Unit), 2020-2025

The Primary Objectives in This Report Are:

To determine the size of the total market opportunity of global and key countries

To assess the growth potential for Rolling Circle Amplification

To forecast future growth in each product and end-use market

To assess competitive factors affecting the marketplace

This report profiles key players in the global Rolling Circle Amplification market based on the following parameters - company overview, sales quantity, revenue, price, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include Thermo Fisher Scientific Inc, Abbott, QIAGEN, Agilent Technologies Inc, Bayer AG, BD, F. Hoffmann-La Roche Ltd, BIOMÉRIEUX, Bio-Rad Laboratories Inc, Takara Bio, Inc, etc.

This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.

Market Segmentation

Rolling Circle Amplification market is split by Type and by Application. For the period 2020-2031, the growth among segments provides accurate calculations and forecasts for consumption value by Type, and by Application in terms of volume and value. This analysis can help you expand your business by targeting qualified niche markets.

Market segment by Type

Enzyme Assisted RCA Biosensor

Aunp RCA Biosensor

Aptamer Biosensors

Small Molecule Biosensors

Transcription Factor Biosensors

Mirna Biosensors

Protein Biosensors

Market segment by Application

Disease Diagnosis

Biosensing

Drug Discovery

Nanotechnology

Other

Major players covered

Thermo Fisher Scientific Inc

Abbott

QIAGEN

Agilent Technologies Inc

Bayer AG

BD

F. Hoffmann-La Roche Ltd

BIOMÉRIEUX

Bio-Rad Laboratories Inc

Takara Bio, Inc

Market segment by region, regional analysis covers

North America (United States, Canada, and Mexico)

Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe)

Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia)

South America (Brazil, Argentina, Colombia, and Rest of South America)

Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa)

The content of the study subjects, includes a total of 15 chapters:

Chapter 1, to describe Rolling Circle Amplification product scope, market overview, market estimation caveats and base year.

Chapter 2, to profile the top manufacturers of Rolling Circle Amplification, with price, sales quantity, revenue, and global market share of Rolling Circle Amplification from 2020 to 2025.

Chapter 3, the Rolling Circle Amplification competitive situation, sales quantity, revenue, and global market share of top manufacturers are analyzed emphatically by landscape contrast.

Chapter 4, the Rolling Circle Amplification breakdown data are shown at the regional level, to show the sales quantity, consumption value, and growth by regions, from 2020 to 2031.

Chapter 5 and 6, to segment the sales by Type and by Application, with sales market share and growth rate by Type, by Application, from 2020 to 2031.

Chapter 7, 8, 9, 10 and 11, to break the sales data at the country level, with sales quantity, consumption value, and market share for key countries in the world, from 2020 to 2025.and Rolling Circle Amplification market forecast, by regions, by Type, and by Application, with sales and revenue, from 2026 to 2031.

Chapter 12, market dynamics, drivers, restraints, trends, and Porters Five Forces analysis.

Chapter 13, the key raw materials and key suppliers, and industry chain of Rolling Circle Amplification.

Chapter 14 and 15, to describe Rolling Circle Amplification sales channel, distributors, customers, research findings and conclusion.