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Global Polydeoxyribonudeotide (PDRN) Supply, Demand and Key Producers, 2026-2032

Publisher GlobalInfoResearch
Published Jan 16, 2026
Length 152 Pages
SKU # GFSH20744154

Description

The global Polydeoxyribonudeotide (PDRN) market size is expected to reach $ 694 million by 2032, rising at a market growth of 31.7% CAGR during the forecast period (2026-2032).

PDRN is deoxyribonucleic acid(DNA) product, mainly comes from semen and roe of fish, rapidly repair injured scars. It can promote the collagen synthesis on the cell surface, reverse aging signs. PDRN is the excellent skin repair product widely used for both high-end beauty products and medical products. Strong functions of anti-radiation and shrinking pores, make skin appears brightly and elastically.

Polydeoxyribonucleotide (PDRN) and polynucleotide (PN) are regenerative materials extracted from the regenerative cell (sperm and testicle) gene segment (DNA) of salmon or trout. The molecular sizes of PDRN and PN are different (PN is bigger) and they are safe biogenic substances approved by the Ministry of Food and Drug Safety. PDRN are often used in pharmaceuticals for tissue regeneration and cornea regeneration as well as treatment and tissue restoration of wounds. PN is often used for medical devices (tissue regeneration) for skin regeneration, articular cartilage regeneration, and osteogenic tissues.

Both PDRN and PN are included in the report.

As a product of regenerative medicine, PDRN can synthesize DNA from damaged or hypoxic tissues, activate the regeneration of endogenous growth factors such as FGF, IGF, and EGF, accelerate cell metabolism, and improve skin repair and regeneration capabilities. The fiber network full of collagen and elastin can achieve skin rejuvenation, improve skin microenvironment, increase skin thickness, etc., so as to achieve the effect of improving problem skin.

The PDRN market has shown a significant growth trend in recent years, mainly driven by the field of regenerative medicine and tissue engineering, as well as the field of aesthetics. Demand for innovative solutions in medical fields such as wound healing, dermatology, orthopedics is driving the demand for PDRN products and therapies.

In terms of product types, freeze-dried powder occupies an important position, dominated with 65% market share in 2024, preferred for stability and versatility in pharmaceuticals and cosmetics. While PDRN Solutions are growing demand in injectables (e.g., mesotherapy), especially in Korea’s "salmon needle" treatments. Expected to surge due to ease of clinical applicationAt the same time, in terms of application, the share of Medical Aesthetics (Mesotherapy) in 2024 is about 32%, used in "regenerative hydrogels" for collagen synthesis and anti-inflammatory effects.

The major global manufacturers of Polydeoxyribonudeotide (PDRN) include HTL Biotechnology, Ruijiming Biological, PharmaResearch Co., Ltd., Humedix, ReaLi Tide Biological, HENGYU BIOPH, Mastelli, Dongkook, BR PHARM, BMI KOREA, BNF Solution, etc. In 2024, the world's top three vendors accounted for approximately 56% of the revenue.

As a new type of regenerative material, PDRN has multiple activities such as promoting skin damage repair, anti-inflammatory, promoting angiogenesis, improving tissue microcirculation, etc. It has broad application prospects in the fields of medical devices, medicine, cosmetics, health foods, daily chemical products, medical cosmetology, etc. In the future, with the rise of medical beauty consumption and the expansion of application fields, the scale of the PDRN market will further expand. The PDRN market is poised for explosive growth, anchored by Asia-Pacific’s dominance (Korea/China) and diversification into cosmetics/wound care. Key developments include China’s regulatory openings, plant-based innovations, and the rise of "regenerative aesthetics."

This report studies the global Polydeoxyribonudeotide (PDRN) production, demand, key manufacturers, and key regions.

This report is a detailed and comprehensive analysis of the world market for Polydeoxyribonudeotide (PDRN) and provides market size (US$ million) and Year-over-Year (YoY) Growth, considering 2025 as the base year. This report explores demand trends and competition, as well as details the characteristics of Polydeoxyribonudeotide (PDRN) that contribute to its increasing demand across many markets.

Highlights and key features of the study

Global Polydeoxyribonudeotide (PDRN) total production and demand, 2021-2032, (Kg)

Global Polydeoxyribonudeotide (PDRN) total production value, 2021-2032, (USD Million)

Global Polydeoxyribonudeotide (PDRN) production by region & country, production, value, CAGR, 2021-2032, (USD Million) & (Kg), (based on production site)

Global Polydeoxyribonudeotide (PDRN) consumption by region & country, CAGR, 2021-2032 & (Kg)

U.S. VS China: Polydeoxyribonudeotide (PDRN) domestic production, consumption, key domestic manufacturers and share

Global Polydeoxyribonudeotide (PDRN) production by manufacturer, production, price, value and market share 2021-2026, (USD Million) & (Kg)

Global Polydeoxyribonudeotide (PDRN) production by Type, production, value, CAGR, 2021-2032, (USD Million) & (Kg)

Global Polydeoxyribonudeotide (PDRN) production by Application, production, value, CAGR, 2021-2032, (USD Million) & (Kg)

This report profiles key players in the global Polydeoxyribonudeotide (PDRN) market based on the following parameters - company overview, production, value, price, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include HTL Biotechnology, ReaLi Tide Biological, PharmaResearch Co., Ltd., Humedix, Ruijiming Biological, Bloomage Biotech, HENGYU BIOPH, Mastelli, Dongkook, BR PHARM, etc.

This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.

Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the World Polydeoxyribonudeotide (PDRN) market

Detailed Segmentation:

Each section contains quantitative market data including market by value (US$ Millions), volume (production, consumption) & (Kg) and average price (US$/g) by manufacturer, by Type, and by Application. Data is given for the years 2021-2032 by year with 2025 as the base year, 2026 as the estimate year, and 2027-2032 as the forecast year.

Global Polydeoxyribonudeotide (PDRN) Market, By Region:
United States
China
Europe
Japan
South Korea
ASEAN
India
Rest of World

Global Polydeoxyribonudeotide (PDRN) Market, Segmentation by Type:
Powder
Solution

Global Polydeoxyribonudeotide (PDRN) Market, Segmentation by Application:
Mesotherapy
Bone Injection & Dermal Fillers
Pharmaceutical
Cosmetic
Wound Healing Products and Others

Companies Profiled:
HTL Biotechnology
ReaLi Tide Biological
PharmaResearch Co., Ltd.
Humedix
Ruijiming Biological
Bloomage Biotech
HENGYU BIOPH
Mastelli
Dongkook
BR PHARM
BNC Global
BMI KOREA
BNF Solution
Nanjing Letop Biotechnology
Topscience Biotech
Freda Biotechnology
Shebah Biotech
APR Corporation
Kolmar Korea
PORIBIO INC.

Key Questions Answered:

1. How big is the global Polydeoxyribonudeotide (PDRN) market?

2. What is the demand of the global Polydeoxyribonudeotide (PDRN) market?

3. What is the year over year growth of the global Polydeoxyribonudeotide (PDRN) market?

4. What is the production and production value of the global Polydeoxyribonudeotide (PDRN) market?

5. Who are the key producers in the global Polydeoxyribonudeotide (PDRN) market?

6. What are the growth factors driving the market demand?

Table of Contents

152 Pages
1 Supply Summary
2 Demand Summary
3 World Manufacturers Competitive Analysis
4 United States VS China VS Rest of the World
5 Market Analysis by Type
6 Market Analysis by Application
7 Company Profiles
8 Industry Chain Analysis
9 Research Findings and Conclusion
10 Appendix
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