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Global G-protein Coupled Receptors Market Size study, By Product (Cell Lines, Detection Kits, Cell Culture Reagents, Ligands), By Assay Type (cAMP Functional Assays, Calcium Functional Assays, ß-Arrestin Functional Assays, Radioligand Binding & GTP?S Func

Publisher Factview Research
Published Oct 03, 2025
Length 285 Pages
SKU # FAVR20464141

Description

The Global G-protein Coupled Receptors (GPCR) Market was valued at USD 3.92 billion in 2024 and is expected to exhibit a compound annual growth rate CAGR of 6.4% over the forecast period from 2024 to 2034. GPCRs, also referred to as seven transmembrane receptors, play a crucial role in cell signaling pathways and are extensively utilized in pharmaceutical research for drug discovery and development. With the increasing burden of chronic diseases such as cancer, cardiovascular disorders, and metabolic syndromes, along with substantial investments in research and development (R&D), the adoption of GPCR-based screening assays is expected to witness exponential growth. The presence of numerous approved drugs and investigational therapies targeting GPCRs further fuels the demand for GPCR-driven drug discovery programs.

Technological advancements such as AI-driven drug discovery platforms and high-resolution structural biology techniques including cryo-electron microscopy (Cryo-EM) and X-ray crystallography are revolutionizing GPCR-based therapeutic innovations. These developments facilitate precise modeling of ligand-receptor interactions, enabling the identification of high-affinity and selective drug candidates. Additionally, the emergence of allosteric modulators and biased agonists is expanding the scope of GPCR-targeted drug design, fostering significant interest in precision medicine and personalized therapeutics.

Despite the promising growth trajectory, the market faces challenges such as the high costs of cell-based assays, complex GPCR signaling mechanisms, and the requirement for skilled professionals in biotechnology and pharmaceutical research. However, strategic collaborations between biopharmaceutical companies, academic institutions, and government research initiatives are mitigating these barriers by fostering innovation and technological breakthroughs. For instance, Exicure's partnership with GPCR Therapeutics in December 2024 aims to advance CXCR4 inhibitor development, currently in Phase 2 clinical trials for multiple myeloma and acute myeloid leukemia.

Regionally, North America accounted for the largest market share of 36.9% in 2024, driven by large-scale R&D investments, rising FDA approvals of GPCR-targeted therapies, and the presence of leading pharmaceutical firms. Meanwhile, Asia-Pacific is expected to witness the fastest CAGR over the forecast period, propelled by growing healthcare infrastructure, expanding biopharmaceutical R&D, and increasing prevalence of chronic illnesses. Countries such as China, Japan, and India are at the forefront, benefiting from government-backed research initiatives and favorable regulatory environments supporting the biotechnology and pharmaceutical industries.

Major market players included in this report are:
  • Thermo Fisher Scientific Inc.
  • Eurofins Scientific
  • QIAGEN
  • WuXi AppTec
  • Promega Corporation
  • Abcam plc
  • Merck KGaA
  • PerkinElmer Inc.
  • Enzo Biochem Inc.
  • BD (Becton, Dickinson and Company)
  • Sosei Heptares
  • Tectonic Therapeutics
  • Antiverse
  • Bio-Techne Corporation
  • Cube Biotech
The detailed segments and sub-segments of the market are explained below:

By Product
  • Cell Lines
  • Detection Kits
  • Cell Culture Reagents
  • Ligands
By Assay Type
  • cAMP Functional Assays
  • Calcium Functional Assays
  • β-Arrestin Functional Assays
  • Radioligand Binding & GTPγS Functional Assays
  • Internalization Assays
  • Trafficking Assays
  • Other Assays
By Application
  • Cancer Research
  • CNS Research
  • Metabolic Research
  • Cardiovascular Research
  • Respiratory Research
  • Inflammation Research
  • Other Applications
By Region:

North America
  • U.S.
  • Canada
Europe
  • UK
  • Germany
  • France
  • Spain
  • Italy
  • Rest of Europe
Asia Pacific
  • China
  • India
  • Japan
  • Australia
  • South Korea
  • Rest of Asia Pacific
Latin America
  • Brazil
  • Mexico
Middle East & Africa
  • Saudi Arabia
  • South Africa
  • Rest of Middle East & Africa
Years considered for the study are as follows:
  • Historical year – 2022
  • Base year – 2024
  • Forecast period – 2024 to 2034
Key Takeaways:
  • Market Estimates & Forecast for 10 years from 2022 to 2034.
  • Annualized revenues and regional level analysis for each market segment.
  • Detailed analysis of the geographical landscape with country-level insights.
  • Competitive landscape with insights on key market players.
  • Strategic recommendations based on emerging market trends.
  • Analysis of demand-side and supply-side factors shaping the industry.

Table of Contents

285 Pages
Chapter 1. Global G-protein Coupled Receptors Market Executive Summary
1.1. Global G-protein Coupled Receptors Market Size & Forecast (2024-2034)
1.2. Regional Summary
1.3. Segmental Summary
1.3.1. By Product
1.3.2. By Assay Type
1.3.3. By Application
1.4. Key Trends
1.5. Recession Impact
1.6. Industry Metrics
1.7. Investment Analysis
1.8 .Investment Rationale
1.9. Analyst Recommendation & Conclusion
Chapter 2. Global G-protein Coupled Receptors Market Definition and Research Assumptions
2.1. Research Objective
2.2. Market Definition
2.3. Research Assumptions
2.3.1. Inclusion & Exclusion
2.3.2. Limitations
2.3.3. Supply Side Analysis
2.3.3.1. Availability
2.3.3.2. Infrastructure
2.3.3.3. Regulatory Environment
2.3.3.4. Market Competition
2.3.3.5. Economic Viability (Consumer’s Perspective)
2.3.4. Demand Side Analysis
2.3.4.1. Regulatory Frameworks
2.3.4.2. Technological Advancements
2.3.4.3. Environmental Considerations
2.3.4.4. Consumer Awareness & Acceptance
2.4. Estimation Methodology
2.5. Years Considered for the Study
2.6. Currency Conversion Rates
Chapter 3. Global G-protein Coupled Receptors Market Dynamics
3.1. Market Drivers
3.1.1. Rising prevalence of chronic diseases and growing demand for drug discovery
3.1.2. Technological advancements in GPCR-based drug screening
3.1.3. Increased investments in precision medicine and biologics
3.2. Market Challenges
3.2.1. High cost of cell-based assays and GPCR-targeting drug development
3.2.2. Complex GPCR signaling pathways limiting direct drug targeting
3.3. Market Opportunities
3.3.1. Integration of AI & Machine Learning for advanced GPCR modeling
3.3.2. Expansion of personalized medicine and precision therapeutics
3.3.3. Collaborations between pharmaceutical companies and biotech startups
Chapter 4. Global G-protein Coupled Receptors Market Industry Analysis
4.1. Porter’s 5 Force Model
4.1.1. Bargaining Power of Suppliers
4.1.2. Bargaining Power of Buyers
4.1.3. Threat of New Entrants
4.1.4. Threat of Substitutes
4.1.5. Competitive Rivalry
4.1.6. Futuristic Approach to Porter’s 5 Force Model
4.1.7. Porter’s 5 Force Impact Analysis
4.2. PESTEL Analysis
4.2.1. Political
4.2.2. Economical
4.2.3. Social
4.2.4. Technological
4.2.5. Environmental
4.2.6. Legal
4.3. Top Investment Opportunity
4.4. Top Winning Strategies
4.5. Disruptive Trends
4.6. Industry Expert Perspective
4.7. Analyst Recommendation & Conclusion
Chapter 5. Global G-protein Coupled Receptors Market Size & Forecasts by Product 2022-2032
5.1. Segment Dashboard
5.2. Global G-protein Coupled Receptors Market: Product Revenue Trend Analysis, 2022 & 2032 (USD Billion)
5.2.1. Cell Lines
5.2.2. Detection Kits
5.2.3. Cell Culture Reagents
5.2.4. Ligands
Chapter 6. Global G-protein Coupled Receptors Market Size & Forecasts by Assay Type 2022-2032
6.1. Segment Dashboard
6.2. Global G-protein Coupled Receptors Market: Assay Type Revenue Trend Analysis, 2022 & 2032 (USD Billion)
6.2.1. cAMP Functional Assays
6.2.2. Calcium Functional Assays
6.2.3. β-Arrestin Functional Assays
6.2.4. Radioligand Binding & GTPγS Functional Assays
6.2.5. Internalization Assays
6.2.6. Trafficking Assays
6.2.7. Other Assays
Chapter 7. Global G-protein Coupled Receptors Market Size & Forecasts by Application 2022-2032
7.1. Segment Dashboard
7.2. Global G-protein Coupled Receptors Market: Application Revenue Trend Analysis, 2022 & 2032 (USD Billion)
7.2.1. Cancer Research
7.2.2. CNS Research
7.2.3. Metabolic Research
7.2.4. Cardiovascular Research
7.2.5. Respiratory Research
7.2.6. Inflammation Research
7.2.7. Other Applications
Chapter 8. Global G-protein Coupled Receptors Market Size & Forecasts by Region 2022-2032
8.1. North America G-protein Coupled Receptors Market
8.1.1. U.S. G-protein Coupled Receptors Market
8.1.1.1. Product breakdown size & forecasts, 2022-2032
8.1.1.2. Assay Type breakdown size & forecasts, 2022-2032
8.1.2. Canada G-protein Coupled Receptors Market
8.2. Europe G-protein Coupled Receptors Market
8.2.1. U.K. G-protein Coupled Receptors Market
8.2.2. Germany G-protein Coupled Receptors Market
8.2.3. France G-protein Coupled Receptors Market
8.2.4. Spain G-protein Coupled Receptors Market
8.2.5. Italy G-protein Coupled Receptors Market
8.2.6. Rest of Europe G-protein Coupled Receptors Market
8.3. Asia-Pacific G-protein Coupled Receptors Market
8.3.1. China G-protein Coupled Receptors Market
8.3.2. India G-protein Coupled Receptors Market
8.3.3. Japan G-protein Coupled Receptors Market
8.3.4. Australia G-protein Coupled Receptors Market
8.3.5. South Korea G-protein Coupled Receptors Market
8.3.6. Rest of Asia Pacific G-protein Coupled Receptors Market
8.4. Latin America G-protein Coupled Receptors Market
8.4.1. Brazil G-protein Coupled Receptors Market
8.4.2. Mexico G-protein Coupled Receptors Market
8.4.3. Rest of Latin America G-protein Coupled Receptors Market
8.5. Middle East & Africa G-protein Coupled Receptors Market
8.5.1. Saudi Arabia G-protein Coupled Receptors Market
8.5.2. South Africa G-protein Coupled Receptors Market
8.5.3. Rest of Middle East & Africa G-protein Coupled Receptors Market
Chapter 9. Competitive Intelligence
9.1. Key Company SWOT Analysis
9.1.1. Thermo Fisher Scientific Inc.
9.1.2. QIAGEN
9.1.3. Merck KGaA
9.2. Top Market Strategies
9.3. Company Profiles
9.3.1. Thermo Fisher Scientific Inc.
9.3.2. Eurofins Scientific
9.3.3. WuXi AppTec
9.3.4. Promega Corporation
9.3.5. Abcam plc
9.3.6. PerkinElmer Inc.
9.3.7. Enzo Biochem Inc.
9.3.8. BD
9.3.9. Sosei Heptares
9.3.10. Tectonic Therapeutics
Chapter 10. Research Process
10.1. Research Process
10.1.1. Data Mining
10.1.2. Analysis
10.1.3. Market Estimation
10.1.4. Validation
10.1.5. Publishing
10.2. Research Attributes

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