Soft tissue neoplasms, also known as abnormal growths arise in connective tissues, such as muscles, fat, blood vessels, nerves, and fibrous tissues. They may be malignant (soft tissue sarcomas) or benign (non-cancerous). Rare yet aggressive, malignant tumors like liposarcoma and leiomyosarcoma can spread to other organs. Chemical carcinogens, radiation exposure, and genetic mutations are risk factors. Painless tumors, edema, or limited mobility are possible symptoms. Treatment options include surgery, radiation, chemotherapy, targeted therapy, and immunotherapy, depending on the type and stage of the tumor. Early diagnosis lowers problems and improves results. Moreover, the rising prevalence is anticipated to positively impact the pipeline landscape for soft tissue neoplasms.
Report Coverage
The Soft Tissue Neoplasms Drug Pipeline Insight Report by Expert Market Research gives comprehensive insights into soft tissue neoplasms therapeutics currently undergoing clinical trials. It covers various aspects related to the details of each of these drugs under development for Soft Tissue Neoplasms. The soft tissue neoplasms report assessment includes the analysis of over 50 pipeline drugs and 25+ companies. The soft tissue neoplasms pipeline landscape will include an analysis based on efficacy and safety measure outcomes published for the trials including their adverse effects on patients suffering from the condition, and alignment with soft tissue neoplasms treatment guidelines to ensure optimal care practices.
The assessment part will include a detailed analysis of each drug, drug class, clinical studies, phase type, drug type, route of administration, and ongoing product development activities related to soft tissue neoplasms.
Soft Tissue Neoplasms Drug Pipeline Outlook
The management of soft tissue neoplasms is based on tumor type, size, location, and malignancy. The main treatment for localized tumors is surgical excision, which guarantees total removal with distinct margins. Before surgery, radiation therapy is used to reduce tumor size. Whereas, after surgery, it is used to eradicate any remaining cancer cells. For cases that are progressed or metastatic, chemotherapy and targeted treatments such as tyrosine kinase inhibitors (TKIs) work well. Immunotherapy is a new treatment for several sarcoma subtypes. Routine monitoring that uses imaging and biopsies enables timely intervention and prevention from recurrence prevention.
The high bioavailability, tumor-penetration capabilities, and tailored effect on cancer pathways make small molecules useful in the treatment of soft tissue neoplasms. These medications, such as tyrosine kinase inhibitors (TKIs), stop tumor growth by blocking signaling pathways and angiogenesis that are necessary for the spread of cancer. Treatment is more convenient because they can be taken orally. Additionally, tiny molecules have fewer long-term negative effects and adjustable dosing due to their shorter half-life. Their ability to effectively target mutations makes them a crucial choice in precision oncology. Further, the rising focus on soft tissue neoplasms emerging drugs and the advances in the understanding of the molecular pathogenesis of the disease are expected to support the pipeline expansion in the coming years.
Soft Tissue Neoplasms Epidemiology
Sarcomas and other soft tissue neoplasms make up around 1% of all malignant tumors, making them comparatively uncommon. The typical diagnosis age is 62 years, and there are about 13,520 new cases identified in the United States each year. Liposarcoma and undifferentiated pleomorphic sarcoma are the most prevalent varieties. Age-specific incidence rates peak among those 65–74 years old. The incidence varies between 15 and 35 per million people worldwide, underscoring the need for more study and education on these aggressive tumors and treatment options.
Soft Tissue Neoplasms Drug Pipeline Therapeutic Assessment
This section of the report covers the analysis of soft tissue neoplasms drug candidates based on several segmentations including:
By Phase
- Late-Stage Products (Phase 3 and Phase 4)
- Mid-Stage Products (Phase 2)
- Early-Stage Products (Phase I)
- Preclinical and Discovery Stage Products
- Small Molecules
- Monoclonal Antibodies
- Peptides
- Recombinant Proteins
- Gene Therapy
- Polymers
- Others
- Oral
- Parenteral
- Others
The report covers phase I, phase II, phase III, phase IV, and early phase drugs. The coverage includes an in-depth analysis of each drug across these phases. According to EMR analysis , phase II covers a major share of the total clinical trials, with a substantial number of soft tissue neoplasm drugs undergoing clinical development.
Soft Tissue Neoplasms – Pipeline Assessment Segmentation, By Drug Classes
The drug molecule categories covered under soft tissue neoplasms pipeline analysis include small molecules, biologics, peptides, and immunotherapies, among others. The soft tissue neoplasms report provides a comparative analysis of the drug classes for each drug in various phases of clinical trials for soft tissue neoplasms.
Soft Tissue Neoplasms Clinical Trials Therapeutic Assessment – Competitive Dynamics
The EMR report for the soft tissue neoplasms drug pipeline covers the profile of key companies involved in clinical trials and their drugs under development. It provides a detailed soft tissue neoplasms therapeutic assessment, analyzing the competitive dynamics of the clinical trial landscape. Below is the list of a few players involved in soft tissue neoplasms clinical trials:
- Daiichi Sankyo Co., Ltd.
- Eli Lilly and Company
- Chipscreen Biosciences, Ltd.
- Adaptimmune
- Ultragenyx Pharmaceutical Inc.
- Salarius Pharmaceuticals, LLC
- Philogen S.p.A.
- SpringWorks Therapeutics, Inc.
- Kazia Therapeutics Limited
- Immunophotonics, Inc.
Major drugs currently in the drug pipeline are as follows:
Drug: LOXO-292
Sponsored by Eli Lilly and Company, the objective of this multicenter clinical trial is to investigate the efficacy and safety of the LOXO-292, a soft tissue neoplasms drug candidate. The study is under Phase I/II clinical development.
Drug: Pexidartinib
Daiichi Sankyo Co., Ltd. is conducting a study aimed at examining the efficacy of the investigational drug pexidartinib for the treatment of soft tissue neoplasms. The study is under Phase II clinical development.
Reasons To Buy This Report
The soft tissue neoplasms drug report provides a strategic overview of the latest and future landscape of treatments for soft tissue neoplasms. it provides necessary information for making informed investment decisions along with research, development, and strategic planning efforts. The stakeholders will benefit from the essential insights into market trends, regulatory environments, and potential growth opportunities within soft tissue neoplasms pipeline insights.
Key Questions Answered in the Soft Tissue Neoplasms – Pipeline Insight Report
- What is the current landscape of soft tissue neoplasm pipeline drugs?
- Which companies/institutions are developing soft tissue neoplasms emerging drugs?
- How many phase II drugs are currently present in soft tissue neoplasms pipeline drugs?
- Which company is leading the soft tissue neoplasms disease pipeline development activities?
- What is the current soft tissue neoplasms therapeutic assessment?
- What are the opportunities and challenges present in the soft tissue neoplasms drug pipeline landscape?
- What is the efficacy and safety profile of soft tissue neoplasm pipeline drugs?
- Which companies/institutions are involved in soft tissue neoplasm collaborations aimed at providing enhanced therapeutic alternatives for patients?
- What are the geographies covered for clinical trials in soft tissue neoplasms?
Global Cancer Therapeutics Market
Global Clinical Trials Market
- 1 Preface
- 1.1 Introduction
- 1.2 Objectives of the Study
- 1.3 Research Methodology & Assumptions
- 2 Executive Summary
- 3 Overview of Soft Tissue Neoplasms
- 3.1 Signs and Symptoms
- 3.2 Causes
- 3.3 Risk Factors
- 3.4 Types of Soft Tissue Neoplasms
- 3.5 Diagnosis
- 3.6 Treatment
- 4 Patient Profile: Soft Tissue Neoplasms
- 4.1 Patient Profile Overview
- 4.2 Patient Psychology and Emotional Impact Factors
- 4.3 Risk Assessment and Treatment Success Rate
- 5 Soft Tissue Neoplasms: Epidemiology Snapshot
- 5.1 Soft Tissue Neoplasms Incidence by Key Markets
- 5.2 Soft Tissue Neoplasms – Patients Seeking Treatment in Key Markets
- 6 Soft Tissue Neoplasms: Market Dynamics
- 6.1 Market Drivers and Constraints
- 6.2 SWOT Analysis
- 7 Soft Tissue Neoplasms: Key Facts Covered
- 7.1 Top Countries Contributing to Clinical Trials in Asia-Pacific
- 7.2 Top Countries Contributing to Clinical Trials in Europe
- 7.3 Top Countries Contributing to Clinical Trials in North America
- 7.4 Top Countries Contributing to Clinical Trials in Other Regions
- 8 Soft Tissue Neoplasms, Drug Pipeline Assessment
- 8.1 Assessment by Treatment Type
- 8.2 Assessment by Route of Administration
- 8.3 Assessment by Drug Class
- 9 EMR Drug Pipeline Comparative Analysis
- 9.1 List of Soft Tissue Neoplasms Pipeline Drugs
- 9.1.1 By Company
- 9.1.2 By Phase
- 9.1.3 By Indication
- 9.1.4 By Trial Status
- 9.1.5 By Funder Type
- 9.2 EMR Attribute Scoring Analysis of Pipeline Drugs (Top Drugs)
- 10 Soft Tissue Neoplasms Drug Pipeline - Late-Stage Products (Phase III and IV) (Top Drugs)
- 10.1 Comparative Analysis for Late-Stage Drugs
- 10.1.1 Study Type
- 10.1.2 Recruitment Status
- 10.1.3 Company
- 10.1.4 Funder Type
- 10.2 Product Level Analysis*
- 10.2.1 Drug: AL3818
- 10.2.1.1 Product Description
- 10.2.1.2 Trial ID
- 10.2.1.3 Sponsor Name
- 10.2.1.4 Study Type
- 10.2.1.5 Drug Class
- 10.2.1.6 Eligibility Criteria
- 10.2.1.7 Study Record Dates
- 10.2.1.7.1 First Submitted
- 10.2.1.7.2 First Posted
- 10.2.1.7.3 Last Update Posted
- 10.2.1.7.4 Last Verified
- 10.2.1.8 Indication
- 10.2.1.9 Study Design
- 10.2.1.10 Recruitment Status
- 10.2.1.11 Enrollment (Estimated)
- 10.2.1.12 Location Countries
- 10.2.1.13 Recent Results
- 10.2.2 Drugs: AL102
- 10.2.3 Other Drugs
- 11 Soft Tissue Neoplasms Drug Pipeline - Mid-Stage Products (Phase II) (Top Drugs)
- 11.1 Comparative Analysis for Mid-Stage Drugs
- 11.1.1 Study Type
- 11.1.2 Recruitment Status
- 11.1.3 Company
- 11.1.4 Funder Type
- 11.2 Product Level Analysis*
- 11.2.1 Drug: Pexidartinib
- 11.2.1.1 Product Description
- 11.2.1.2 Trial ID
- 11.2.1.3 Sponsor Name
- 11.2.1.4 Study Type
- 11.2.1.5 Drug Class
- 11.2.1.6 Eligibility Criteria
- 11.2.1.7 Study Record Dates
- 11.2.1.7.1 First Submitted
- 11.2.1.7.2 First Posted
- 11.2.1.7.3 Last Update Posted
- 11.2.1.7.4 Last Verified
- 11.2.1.8 Indication
- 11.2.1.9 Study Design
- 11.2.1.10 Recruitment Status
- 11.2.1.11 Enrollment (Estimated)
- 11.2.1.12 Location Countries
- 11.2.1.13 Recent Results
- 11.2.2 Drug: Dacarbazine
- 11.2.3 Other Drugs
- 12 Soft Tissue Neoplasms Drug Pipeline - Early-Stage Products (Phase I) (Top Drugs)
- 12.1 Comparative Analysis for Early-Stage Drugs
- 12.1.1 Study Type
- 12.1.2 Recruitment Status
- 12.1.3 Company
- 12.1.4 Funder Type
- 12.2 Product Level Analysis*
- 12.2.1 Drug: LOXO-292
- 12.2.1.1 Product Description
- 12.2.1.2 Trial ID
- 12.2.1.3 Sponsor Name
- 12.2.1.4 Study Type
- 12.2.1.5 Drug Class
- 12.2.1.6 Eligibility Criteria
- 12.2.1.7 Study Record Dates
- 12.2.1.7.1 First Submitted
- 12.2.1.7.2 First Posted
- 12.2.1.7.3 Last Update Posted
- 12.2.1.7.4 Last Verified
- 12.2.1.8 Indication
- 12.2.1.9 Study Design
- 12.2.1.10 Recruitment Status
- 12.2.1.11 Enrollment (Estimated)
- 12.2.1.12 Location Countries
- 12.2.2 Drugs: L19TNF
- 12.2.3 Other Drugs
- 13 Soft Tissue Neoplasms, Key Drug Pipeline Companies
- 13.1 Daiichi Sankyo Co., Ltd.
- 13.1.1 Company Snapshot
- 13.1.2 Pipeline Product Portfolio
- 13.1.3 Financial Analysis
- 13.1.4 Recent News and Developments
- 13.2 Eli Lilly and Company
- 13.2.1 Company Snapshot
- 13.2.2 Pipeline Product Portfolio
- 13.2.3 Financial Analysis
- 13.2.4 Recent News and Developments
- 13.3 Chipscreen Biosciences, Ltd.
- 13.3.1 Company Snapshot
- 13.3.2 Pipeline Product Portfolio
- 13.3.3 Financial Analysis
- 13.3.4 Recent News and Developments
- 13.4 Adaptimmune
- 13.4.1 Company Snapshot
- 13.4.2 Pipeline Product Portfolio
- 13.4.3 Financial Analysis
- 13.4.4 Recent News and Developments
- 13.5 Ultragenyx Pharmaceutical Inc.
- 13.5.1 Company Snapshot
- 13.5.2 Pipeline Product Portfolio
- 13.5.3 Financial Analysis
- 13.5.4 Recent News and Developments
- 13.6 Salarius Pharmaceuticals, LLC
- 13.6.1 Company Snapshot
- 13.6.2 Pipeline Product Portfolio
- 13.6.3 Financial Analysis
- 13.6.4 Recent News and Developments
- 13.7 Philogen S.p.A.
- 13.7.1 Company Snapshot
- 13.7.2 Pipeline Product Portfolio
- 13.7.3 Financial Analysis
- 13.7.4 Recent News and Developments
- 13.8 SpringWorks Therapeutics, Inc.
- 13.8.1 Company Snapshot
- 13.8.2 Pipeline Product Portfolio
- 13.8.3 Financial Analysis
- 13.8.4 Recent News and Developments
- 13.9 Kazia Therapeutics Limited
- 13.9.1 Company Snapshot
- 13.9.2 Pipeline Product Portfolio
- 13.9.3 Financial Analysis
- 13.9.4 Recent News and Developments
- 13.10 Immunophotonics, Inc.
- 13.10.1 Company Snapshot
- 13.10.2 Pipeline Product Portfolio
- 13.10.3 Financial Analysis
- 13.10.4 Recent News and Developments
- 14 Regulatory Framework for Drug Approval, By Region
- 15 Terminated or Suspended Pipeline Products
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