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Proton Pump Inhibitors (PPIs) Market Report and Forecast 2025-2034

Publisher Expert Market Research
Published Jul 28, 2025
Length 350 Pages
SKU # EMAR20319933

Description

The global proton pump inhibitors (PPIs) market size was valued at USD 3.34 Billion in 2024, driven by the rising incidence of gastroesophageal reflux disease (GERD) cases across the globe. The market is expected to grow at a CAGR of 4.50% during the forecast period of 2025-2034, to reach USD 5.19 Billion by 2034.

Proton Pump Inhibitors (PPIs): Introduction

Proton pump inhibitors are medicines used to control the acid released through the glands in the lining of the stomach. They are used to relieve the symptoms of acid reflux or gastroesophageal reflux disease (GERD), along with treating stomach ulcers and damage to the lower esophagus caused by acid reflux. Omeprazole, Esomeprazole, and Lansoprazole are some of the most common types of proton pump inhibitors sold in the market.

Global Proton Pump Inhibitors (PPIs) Market Analysis

In the historical period, the proton pump inhibitors (PPIs) market value has observed a significant upswing owing to the high accessibility and affordability of the drugs. The market is segmented into over-the-counter drugs and prescription drugs like Rabeprazole and Pantoprazole, among others. In addition, a rise in the prevalence of gastrointestinal disorders like peptic ulcers and GERD, especially driven by lifestyle and an aging population have driven the high market demand.

With a deeper understanding of human physiology, coupled with improving research and development infrastructure, health institutions have identified the potential risks of prolonged PPI usage which include kidney damage, osteoporosis, and infections. As a result, the proton pump inhibitors (PPIs) market growth has slowed down in recent years. There is immense focus on cautious prescribing practices along with rising development of generic and novel drugs. Along with novel drug formulations, non-pharmacological treatments are also emerging in the market, which are expected to affect the market.

Global Proton Pump Inhibitors (PPIs) Market Segmentation

Market Breakup by Product Type
  • OTC Drugs
  
  • Omeprazole

    •   
  • Lansoprazole

    •   
  • Esomeprazole

    •   
  • Other OTC Drugs
    • Prescription Drugs
      
  • Rabeprazole

    •   
  • Dexlansoprazole

    •   
  • Pantoprazole

    • Market Breakup by Region
    • North America
    • Europe
    • Asia Pacific
    • Latin America
    • Middle East and Africa
    Global Proton Pump Inhibitors (PPIs) Market Overview

    The United States has held significant proton pump inhibitors (PPIs) market share in the historical period. The presence of key healthcare players which are continuously working to acquire smaller companies and drive innovation through improved research and development and expanding market reach is a vital factor. Moreover, the regulatory authorities like FDA closely monitor the safety profile of PPIs, their potential side effects and promoting quality distribution of the drugs._x000D_

    Europe, being home to several influential healthcare and academic institutions, is contributing to fostering the proton pump inhibitors (PPIs) market demand in the region. With high prevalence of gastrointestinal diseases, especially in the geriatric population, makes the region a major market for PPIs.

    The Asia Pacific region with rising development and improving healthcare infrastructure is expected to witness rapid growth in the forecast period. The region is experiencing several foreign investments from major healthcare companies, which are working on setting up research labs in the region. With such initiatives, they can leverage the area’s academic talent to develop novel drugs.

    Global Proton Pump Inhibitors (PPIs) Market: Competitor Landscape

    The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:
    • AstraZeneca
    • Bayer AG
    • Cadila Pharmaceuticals
    • GlaxoSmithKline PLC
    • Pfizer
    • Eisai Pharmaceuticals
    • Santarus, Inc
    • Wyeth
    • Janssen Pharmaceutical
    • Takeda Pharmaceutical Company Limited
    • Sanofi S.A.
    • Teva Pharmaceuticals
    • Eli Lilly
    Please note that this only represents a partial list of companies, and the complete list has been provided in the report.

    Key Highlights of the Report

    Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
    • Product Type
    • Region
    • OTC Drugs
    • Prescription Drugs
    • North America
    • Europe
    • Asia Pacific
    • Latin America
    • Middle East and Africa
    • Market Drivers and Constraints
    • SWOT Analysis
    • Porter’s Five Forces Model
    • Key Demand Indicators
    • Key Price Indicators
    • Industry Events, Initiatives, and Trends
    • Value Chain Analysis
    • Market Structure
    • Company Profiles
      
  • Financial Analysis

    •   
  • Product Portfolio

    •   
  • Demographic Reach and Achievements

    •   
  • Mergers and Acquisitions

    •   
  • Certifications
    • AstraZeneca
    • Bayer AG
    • Cadila Pharmaceuticals
    • GlaxoSmithKline PLC
    • Pfizer
    • Eisai Pharmaceuticals
    • Santarus, Inc
    • Wyeth
    • Janssen Pharmaceutical
    • Takeda Pharmaceutical Company Limited
    • Sanofi S.A.
    • Teva Pharmaceuticals
    • Eli Lilly
    *Please Note:* The report will take 5 business days to complete, after order confirmation.

    Table of Contents

    350 Pages
    1 Preface
    1.1 Objectives of the Study
    1.2 Key Assumptions
    1.3 Report Coverage – Key Segmentation and Scope
    1.4 Research Methodology
    2 Executive Summary
    3 Global Proton Pump Inhibitors Market Overview
    3.1 Global Proton Pump Inhibitors Market Historical Value (2018-2024)
    3.2 Global Proton Pump Inhibitors Market Forecast Value (2025-2034)
    4 Global Proton Pump Inhibitors Market Landscape
    4.1 Global Proton Pump Inhibitors Developers Landscape
    4.1.1 Analysis by Year of Establishment
    4.1.2 Analysis by Company Size
    4.1.3 Analysis by Region
    4.2 Global Proton Pump Inhibitors Product Landscape
    4.2.1 Analysis by Product Type
    4.2.2 Analysis by Type
    4.2.3 Analysis by Applications
    5 Global Proton Pump Inhibitors Market Dynamics
    5.1 Market Drivers and Constraints
    5.2 SWOT Analysis
    5.3 Porter’s Five Forces Model
    5.4 Key Demand Indicators
    5.5 Key Price Indicators
    5.6 Industry Events, Initiatives, and Trends
    5.7 Value Chain Analysis
    6 Global Proton Pump Inhibitors Market Segmentation
    6.1 Global Proton Pump Inhibitors Market by Product Type
    6.1.1 Market Overview
    6.1.2 OTC Drugs
    6.1.2.1 Omeprazole
    6.1.2.2 Lansoprazole
    6.1.2.3 Esomeprazole
    6.1.2.4 Other OTC Drugs
    6.1.3 Prescription Drugs
    6.1.3.1 Rabeprazole
    6.1.3.2 Dex lansoprazole
    6.1.3.3 Pantoprazole
    6.2 Global Proton Pump Inhibitors Market by Region
    6.2.1 Market Overview
    6.2.2 North America
    6.2.3 Europe
    6.2.4 Asia Pacific
    6.2.5 Latin America
    6.2.6 Middle East and Africa
    7 North America Proton Pump Inhibitors Market
    7.1 Market Share by Country
    7.2 United States of America
    7.3 Canada
    8 Europe Proton Pump Inhibitors Market
    8.1 Market Share by Country
    8.2 United Kingdom
    8.3 Germany
    8.4 France
    8.5 Italy
    8.6 Others
    9 Asia Pacific Proton Pump Inhibitors Market
    9.1 Market Share by Country
    9.2 China
    9.3 Japan
    9.4 India
    9.5 ASEAN
    9.6 Australia
    9.7 Others
    10 Latin America Proton Pump Inhibitors Market
    10.1 Market Share by Country
    10.2 Brazil
    10.3 Argentina
    10.4 Mexico
    10.5 Others
    11 Middle East and Africa Proton Pump Inhibitors Market
    11.1 Market Share by Country
    11.2 Saudi Arabia
    11.3 United Arab Emirates
    11.4 Nigeria
    11.5 South Africa
    11.6 Others
    12 Patent Analysis
    12.1 Analysis by Type of Patent
    12.2 Analysis by Publication year
    12.3 Analysis by Issuing Authority
    12.4 Analysis by Patent Age
    12.5 Analysis by CPC Analysis
    12.6 Analysis by Patent Valuation
    12.7 Analysis by Key Players
    13 Grants Analysis
    13.1 Analysis by year
    13.2 Analysis by Amount Awarded
    13.3 Analysis by Issuing Authority
    13.4 Analysis by Grant Application
    13.5 Analysis by Funding Institute
    13.6 Analysis by NIH Departments
    13.7 Analysis by Recipient Organization
    14 Funding Analysis
    14.1 Analysis by Funding Instances
    14.2 Analysis by Type of Funding
    14.3 Analysis by Funding Amount
    14.4 Analysis by Leading Players
    14.5 Analysis by Leading Investors
    14.6 Analysis by Geography
    15 Partnership and Collaborations Analysis
    15.1 Analysis by Partnership Instances
    15.2 Analysis by Type of Partnership
    15.3 Analysis by Leading Players
    15.4 Analysis by Geography
    16 Regulatory Framework
    16.1 Regulatory Overview
    16.1.1 US FDA
    16.1.2 EU EMA
    16.1.3 INDIA CDSCO
    16.1.4 JAPAN PMDA
    16.1.5 Others
    17 Supplier Landscape
    17.1 AstraZeneca
    17.1.1 Financial Analysis
    17.1.2 Product Portfolio
    17.1.3 Demographic Reach and Achievements
    17.1.4 Mergers and Acquisition
    17.1.5 Certifications
    17.2 Bayer AG
    17.2.1 Financial Analysis
    17.2.2 Product Portfolio
    17.2.3 Demographic Reach and Achievements
    17.2.4 Mergers and Acquisition
    17.2.5 Certifications
    17.3 Cadila Pharmaceuticals
    17.3.1 Financial Analysis
    17.3.2 Product Portfolio
    17.3.3 Demographic Reach and Achievements
    17.3.4 Mergers and Acquisition
    17.3.5 Certifications
    17.4 GlaxoSmithKline PLC
    17.4.1 Financial Analysis
    17.4.2 Product Portfolio
    17.4.3 Demographic Reach and Achievements
    17.4.4 Mergers and Acquisition
    17.4.5 Certifications
    17.5 Pfizer
    17.5.1 Financial Analysis
    17.5.2 Product Portfolio
    17.5.3 Demographic Reach and Achievements
    17.5.4 Mergers and Acquisition
    17.5.5 Certifications
    17.6 Eisai Pharmaceuticals
    17.6.1 Financial Analysis
    17.6.2 Product Portfolio
    17.6.3 Demographic Reach and Achievements
    17.6.4 Mergers and Acquisition
    17.6.5 Certifications
    17.7 Santarus, Inc
    17.7.1 Financial Analysis
    17.7.2 Product Portfolio
    17.7.3 Demographic Reach and Achievements
    17.7.4 Mergers and Acquisition
    17.7.5 Certifications
    17.8 Wyeth
    17.8.1 Financial Analysis
    17.8.2 Product Portfolio
    17.8.3 Demographic Reach and Achievements
    17.8.4 Mergers and Acquisition
    17.8.5 Certifications
    17.9 Janssen Pharmaceutical
    17.9.1 Financial Analysis
    17.9.2 Product Portfolio
    17.9.3 Demographic Reach and Achievements
    17.9.4 Mergers and Acquisition
    17.9.5 Certifications
    17.10 Takeda Pharmaceutical Company Limited
    17.10.1 Financial Analysis
    17.10.2 Product Portfolio
    17.10.3 Demographic Reach and Achievements
    17.10.4 Mergers and Acquisition
    17.10.5 Certifications
    17.11 Sanofi S.A.
    17.11.1 Financial Analysis
    17.11.2 Product Portfolio
    17.11.3 Demographic Reach and Achievements
    17.11.4 Mergers and Acquisition
    17.11.5 Certifications
    17.12 Teva Pharmaceuticals
    17.12.1 Financial Analysis
    17.12.2 Product Portfolio
    17.12.3 Demographic Reach and Achievements
    17.12.4 Mergers and Acquisition
    17.12.5 Certifications
    17.13 Eli Lilly
    17.13.1 Financial Analysis
    17.13.2 Product Portfolio
    17.13.3 Demographic Reach and Achievements
    17.13.4 Mergers and Acquisition
    17.13.5 Certifications
    18 Global Proton Pump Inhibitors Market - Distribution Model (Additional Insight)
    18.1 Overview
    18.2 Potential Distributors
    18.3 Key Parameters for Distribution Partner Assessment
    19 Key Opinion Leaders (KOL) Insights (Additional Insight)
    20 Company Competitiveness Analysis (Additional Insight)
    20.1 Very Small Companies
    20.2 Small Companies
    20.3 Mid-Sized Companies
    20.4 Large Companies
    20.5 Very Large Companies
    21 Payment Methods (Additional Insight)
    21.1 Government Funded
    21.2 Private Insurance
    21.3 Out-of-Pocket

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