Report cover image

Polycystic Kidney Disease Drugs Market Report and Forecast 2025-2034

Published Jul 29, 2025
Length 350 Pages
SKU # EMAR20320021

Description

The polycystic kidney disease drugs market was valued at USD 0.51 Billion in 2024, driven by rising incidence of autosomal dominant polycystic kidney disease across the 8 major markets. The market is expected to grow at a CAGR of 5.90% during the forecast period of 2025-2034, with the values likely to reach USD 0.90 Billion by 2034.

Polycystic Kidney Disease Drugs Market Overview

Polycystic kidney disease (PKD) drugs are designed to address the formation of fluid-filled cysts in kidneys, which can lead to kidney dysfunction. The rising prevalence of PKD and the urgent need for effective treatments are driving market growth. The application of advanced technologies such as artificial intelligence and machine learning to generate high efficacy drugs is expected to impact the market landscape significantly. In addition, continued research initiatives, focused on significantly enhancing the scope and growth of the PKD drugs is amongst the major market trends.

Polycystic Kidney Disease Drugs Market Growth Drivers

Increasing Prevalence of Polycystic Kidney Disease (PKD) to Affect the Market Landscape Significantly

Autosomal dominant polycystic kidney disease (ADPKD) is the most common form of polycystic kidney disease, affecting 1 in 500 to 1,000 individuals globally. It is especially exacerbated by diabetes and hypertension. Consequently, rising prevalence of diabetes and obesity, which can be attributed to sedentary lifestyle and lack of an exercise regime can lead to heightened demand for polycystic kidney disease drugs in the coming years.

Surge in FDA Approvals to Meet Rising Polycystic Kidney Disease Drugs Market Demand

In September 2023, the United States FDA approved Eli Lilly’s Jardiance® (empagliflozin) 10 mg tablets for the treatment of chronic kidney disease (CKD). This approval introduced a promising treatment option for over 35 million affected adults, marking a substantial milestone in CKD management. Empagliflozin demonstrated efficacy in slowing CKD progression, as evidenced in the EMPA-KIDNEY phase III trial, and included a notable reduction in hospitalization risks as well.

Polycystic Kidney Disease Drugs Market Trends

The market is witnessing several trends and developments to improve the current global scenario. Some of the notable trends are as follows:

Adoption of Innovative Methodologies to Develop Effective Drugs

The persistent lack of targeted therapies to halt cyst growth and preserve kidney function underscores the urgent need for innovation drug development in PKD, potentially reshaping treatment approaches.

Suge in Research Efforts

Expanding research endeavors into PKD pathophysiology hold the potential to revolutionize treatment paradigms by unravelling novel therapeutic targets and paving the way for precision medicine tailored to individual patient profile.

Advancements in Technology

Technological innovations like high-output screening and computational modeling expedite the identification and optimization of potential PKD drug candidates. Such advancements usher in next-generation treatments with enhanced efficacy and safety profiles. Drug repurposing intended to recognize new clinical indications for approved or investigational medications is being employed in drug development, attributed to its cost efficiency and time saving benefits.

Increasing Preference for Personalized medicines

The increasing adoption of personalized medicine approaches, leveraging genomics and biomarker to reshape PKD drugs is a significant market trend. It can enable tailored therapeutic interventions based on individual patient characteristics, ultimately enhancing patient care and quality of life.

Polycystic Kidney Disease Drugs Market Segmentation

The EMR’s report titled “Polycystic Kidney Disease Drugs Market Report and Forecast 2025-2034” offers a detailed analysis of the market based on the following segments:

Market Breakup by Disease Type
  • Autosomal Dominant Polycystic Kidney Disease
  • Autosomal Recessive Polycystic Kidney Disease
Market Breakup by Route of Administration
  • Oral
  • Parenteral
  • Others
Market Breakup by Distribution Channel
  • Hospital Pharmacies
  • Retail Pharmacies
  • Others
Market Breakup by Region
  • United States
  • EU-4 and the United Kingdom
  
  • Germany

  •   
  • France

  •   
  • Italy

  •   
  • Spain

  •   
  • United Kingdom
    • Japan
    • India
    Polycystic Kidney Disease Drugs Market Share

    Autosomal Dominant Polycystic Kidney Disease (ADPKD) Leads the Market Share Based on Type

    The market segmentation based on disease type is divided into autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD). Out of these, ADPKD emerges as the predominant leader in the polycystic kidney disease drugs market. Its high prevalence among PKD cases secures a significant market share, surpassing its rare counterpart, autosomal recessive polycystic kidney disease (ARPKD).

    Polycystic Kidney Disease Drugs Market Analysis by Region

    The market for polycystic kidney disease drugs spans across United States, EU-4 (Germany, France, Italy and Spain), the United Kingdom, Japan and India, with each region significantly contributing to its dynamics. United States stands out as a market leader. Its market value due can be accredited to higher prevalence of PKD in the region. Having a robust regulatory infrastructure also adds notable value. In March 2024, Vertex Pharmaceuticals (VRTX ) received U.S. Food and Drug Administration (FDA) approval for VX- 407, an investigational drug targeting ADPKD. VX-407 is a small molecular corrector, which addresses the underlying cause of ADPKD in patients with specific PKD1 genetic variants.

    ADPKD is the most common inherited kidney disease that affects an estimated 250,000 individuals in the United States and Europe combined. Consequently, Europe also holds a significant market share for polycystic kidney disease drugs. In Europe, the presence of affluent research institutions along with a well-established research infrastructure play a critical role in boosting the market value.

    Leading Players in the Polycystic Kidney Disease Drugs Market

    They key features of the market report include patent analyses, grants analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:

    F. Hoffmann-La Roche Ltd

    F. Hoffmann-La Roche Ltd, headquartered in Basel, Switzerland, was founded in 1896. The company specializes in pharmaceutical manufacturing and is a leader in the field of cancer drug development and sales. Roche has developed drugs and diagnostics for various disease, including PKD-1 inhibitors. Some of the drugs include Mycophenolate Mofetil (Cellcept), and Valganciclovir (Valcyte).

    Galapagos NV

    Galapagos NV, founded in 1999 as a joint venture between Crucell and Tibotec, is headquartered in Mechelen, Belgium. The company specializes in pharmaceutical research and is developing GLPG2737, a CFTR1 inhibitor to treat polycystic kidney disease (ADPKD).

    Johnson & Johnson Services, Inc.

    Johnson & Johnson Services, Inc. was established in 1886 in New Brunswick. The company is developing JNJ-0237, an oral medication to treat ADPKD.

    Merck and Co. Inc.

    Merck and Co. Inc. was founded in 1891, in New York. The company is amongst the leading companies in pharmaceutical development and boasts an elaborate drugs portfolio for a variety of diseases including polycystic kidney disease.

    Other companies in the market include AbbVie Inc., Apotex Inc., Amgen Inc., Otsuka Holdings Co. Ltd., Palladio Biosciences Inc., Regulus Therapeutics, Sanofi SA, XORTX Therapeutics Inc., Novartis AG, Teva Pharmaceutical Industries Ltd, and Bayer AG.

    Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.

    Key Questions Answered in the Polycystic Kidney Disease Drugs Market Report
    • What was the polycystic kidney disease drugs market value in 2024?
    • What is the polycystic kidney disease drugs market forecast outlook for 2025-2034?
    • What are the regional markets covered in the EMR report?
    • What are the major factors aiding the polycystic kidney disease drugs market demand?
    • What are the market's major drivers, opportunities, and restraints?
    • Which regional market is expected to lead the market share in the forecast period?
    • Which country is expected to experience expedited growth during the forecast period?
    • What are the major polycystic kidney disease drugs market trends?
    • What is the market segmentation based on route of administration?
    • What is the market breakup based on disease types?
    • What is the market segmentation based on distribution channels?
    • How does the rise in the geriatric population impact the market size?
    • Who are the key players involved in the polycystic kidney disease drugs market?
    • What are the current unmet needs and challenges in the market?
    • How are partnerships, collaborations, mergers and acquisitions among the key market players shaping the market dynamics?
    • What is the clinical trials landscape of the market?
    • What is the patent scenario of the market?
    • Which factors contribute to the dominance of ADPKD drugs in the market?
    *Please Note:* The report will take 5 business days to complete, after order confirmation.

    Table of Contents

    350 Pages
    1 Preface
    1.1 Objectives of the Study
    1.2 Key Assumptions
    1.3 Report Coverage – Key Segmentation and Scope
    1.4 Research Methodology
    2 Executive Summary
    3 Polycystic Kidney Disease Drugs Market Overview: 8 Major Markets
    3.1 Polycystic Kidney Disease Drugs Market Historical Value (2018-2024)
    3.2 Polycystic Kidney Disease Drugs Market Forecast Value (2025-2034)
    4 Polycystic Kidney Disease Overview
    4.1 Guidelines and Stages
    4.2 Pathophysiology
    4.3 Screening and Diagnosis
    4.4 Therapy Pathway
    5 Patient Profile
    5.1 Patient Profile Overview
    5.2 Patient Psychology and Emotional Impact Factors
    5.3 Risk Assessment and Therapy Success Rate
    6 Polycystic Kidney Disease Epidemiology Scenario and Forecast – 8 Major Markets
    6.1 8MM Epidemiology Scenario Overview (2018-2034)
    6.2 United States Polycystic Kidney Disease Epidemiology Scenario and Forecast (2018-2034)
    6.3 EU-4 and United Kingdom Polycystic Kidney Disease Epidemiology Scenario and Forecast (2018-2034)
    6.3.1 Germany Polycystic Kidney Disease Epidemiology Scenario and Forecast (2018-2034)
    6.3.1.1 France Polycystic Kidney Disease Epidemiology Scenario and Forecast (2018-2034)
    6.3.1.2 Italy Polycystic Kidney Disease Epidemiology Scenario and Forecast (2018-2034)
    6.3.1.3 Spain Polycystic Kidney Disease Epidemiology Scenario and Forecast (2018-2034)
    6.3.1.4 United Kingdom Polycystic Kidney Disease Epidemiology Scenario and Forecast (2018-2034)
    6.4 Japan Polycystic Kidney Disease Epidemiology Scenario and Forecast (2018-2034)
    6.5 India Polycystic Kidney Disease Epidemiology Scenario and Forecast (2018-2034)
    7 Polycystic Kidney Disease Drugs Market Landscape: 8 Major Markets*
    7.1 Polycystic Kidney Disease Drugs: Developers Landscape
    7.1.1 Analysis by Year of Establishment
    7.1.2 Analysis by Company Size
    7.1.3 Analysis by Region
    7.2 Polycystic Kidney Disease Drugs: Product Landscape
    7.2.1 Analysis by Indication
    7.2.2 Analysis by Drug Class
    7.2.3 Analysis by Route of Administration
    8 Polycystic Kidney Disease Therapy Challenges and Unmet Needs
    8.1 Therapy Pathway Challenges
    8.2 Compliance and Drop-Out Analysis
    8.3 Awareness and Prevention Gaps
    9 Polycystic Kidney Disease Drugs Market Dynamics
    9.1 Market Drivers and Constraints
    9.2 SWOT Analysis
    9.2.1 Strengths
    9.2.2 Weaknesses
    9.2.3 Opportunities
    9.2.4 Threats
    9.3 Porter’s Five Forces Model
    9.3.1 Bargaining Power of Suppliers
    9.3.2 Bargaining Power of Buyers
    9.3.3 Threat of New Entrants
    9.3.4 Threat of Substitutes
    9.3.5 Degree of Rivalry
    9.4 Key Demand Indicators
    9.5 Key Price Indicators
    9.6 Industry Events, Initiatives, and Trends
    9.7 Value Chain Analysis
    10 Polycystic Kidney Disease Drugs Market Segmentation: 8 Major Markets
    10.1 Polycystic Kidney Disease Drugs Market by Disease Type
    10.1.1 Market Overview
    10.1.2 Autosomal Dominant Polycystic Kidney Disease
    10.1.3 Autosomal Recessive Polycystic Kidney Disease
    10.2 Polycystic Kidney Disease Drugs Market by Route of Administration
    10.2.1 Market Overview
    10.2.2 Oral
    10.2.3 Parenteral
    10.2.4 Others
    10.3 Polycystic Kidney Disease Drugs Market by Distribution Channel
    10.3.1 Market Overview
    10.3.2 Hospital Pharmacies
    10.3.3 Retail Pharmacies
    10.3.4 Others
    10.4 Polycystic Kidney Disease Drugs Market by Region
    10.4.1 Market Overview
    10.4.2 United States
    10.4.3 EU-4 and the United Kingdom
    10.4.3.1 Germany
    10.4.3.2 France
    10.4.3.3 Italy
    10.4.3.4 Spain
    10.4.3.5 United Kingdom
    10.4.4 Japan
    10.4.5 India
    11 United States Polycystic Kidney Disease Drugs Market (218-2034)
    11.1 United States Polycystic Kidney Disease Drugs Market Historical Value (2018-2024)
    11.2 United States Polycystic Kidney Disease Drugs Market Forecast Value (2025-2034)
    11.3 United States Polycystic Kidney Disease Drugs Market (2018-2034) by Disease Type
    11.3.1 Market Overview
    11.3.2 Autosomal Dominant Polycystic Kidney Disease
    11.3.3 Autosomal Recessive Polycystic Kidney Disease
    11.4 United States Polycystic Kidney Disease Drugs Market (2018-2034) by Route of Administration
    11.4.1 Market Overview
    11.4.2 Oral
    11.4.3 Parenteral
    11.4.4 Others
    12 EU-4 and United Kingdom Polycystic Kidney Disease Drugs Market (218-2034)
    12.1 EU-4 and United Kingdom Polycystic Kidney Disease Drugs Market Historical Value (2018-2024)
    12.2 EU-4 and United Kingdom Polycystic Kidney Disease Drugs Market Forecast Value (2025-2034)
    12.3 EU-4 and United Kingdom Polycystic Kidney Disease Drugs Market (2018-2034) by Disease Type
    12.3.1 Market Overview
    12.3.2 Autosomal Dominant Polycystic Kidney Disease
    12.3.3 Autosomal Recessive Polycystic Kidney Disease
    12.4 EU-4 and United Kingdom Polycystic Kidney Disease Drugs Market (2018-2034) by Route of Administration
    12.4.1 Market Overview
    12.4.2 Oral
    12.4.3 Parenteral
    12.4.4 Others
    13 Japan Polycystic Kidney Disease Drugs Market
    13.1 Japan Polycystic Kidney Disease Drugs Market Historical Value (2018-2024)
    13.2 Japan Polycystic Kidney Disease Drugs Market Forecast Value (2025-2034)
    13.3 Japan Polycystic Kidney Disease Drugs Market (2018-2034) by Disease Type
    13.3.1 Market Overview
    13.3.2 Autosomal Dominant Polycystic Kidney Disease
    13.3.3 Autosomal Recessive Polycystic Kidney Disease
    13.4 Japan Polycystic Kidney Disease Drugs Market (2018-2034) by Route of Administration
    13.4.1 Market Overview
    13.4.2 Oral
    13.4.3 Parenteral
    13.4.4 Others
    14 India Polycystic Kidney Disease Drugs Market
    14.1 India Polycystic Kidney Disease Drugs Market (2018-2034) Historical Value (2018-2024)
    14.2 India Polycystic Kidney Disease Drugs Market (2018-2034) Forecast Value (2025-2034)
    14.3 India Polycystic Kidney Disease Drugs Market (2018-2034) by Disease Type
    14.3.1 Market Overview
    14.3.2 Autosomal Dominant Polycystic Kidney Disease
    14.3.3 Autosomal Recessive Polycystic Kidney Disease
    14.4 India Polycystic Kidney Disease Drugs Market (2018-2034) by Route of Administration
    14.4.1 Market Overview
    14.4.2 Oral
    14.4.3 Parenteral
    14.4.4 Others
    15 Regulatory Framework
    15.1 Regulatory Overview
    15.2 US FDA
    15.3 EU EMA
    15.4 INDIA CDSCO
    15.5 JAPAN PMDA
    15.6 Others
    16 Patent Analysis
    16.1 Analysis by Type of Patent
    16.2 Analysis by Publication Year
    16.3 Analysis by Issuing Authority
    16.4 Analysis by Patent Age
    16.5 Analysis by CPC Analysis
    16.6 Analysis by Patent Valuation
    16.7 Analysis by Key Players
    17 Clinical Trial Analysis
    17.1 Analysis by Trial Registration Year
    17.2 Analysis by Trial Status
    17.3 Analysis by Trial Phase
    17.4 Analysis by Therapeutic Area
    17.5 Analysis by Geography
    18 Grant Analysis
    18.1 Analysis by Year
    18.2 Analysis by Amount Awarded
    18.3 Analysis by Issuing Authority
    18.4 Analysis by Grant Product
    18.5 Analysis by Funding Institute
    18.6 Analysis by Departments
    18.7 Analysis by Recipient Organization
    19 Funding and Investment Analysis
    19.1 Analysis by Funding Instances
    19.2 Analysis by Type of Funding
    19.3 Analysis by Funding Amount
    19.4 Analysis by Leading Players
    19.5 Analysis by Leading Investors
    19.6 Analysis by Geography
    20 Partnership and Collaborations Analysis
    20.1 Analysis by Partnership Instances
    20.2 Analysis by Type of Partnership
    20.3 Analysis by Leading Players
    20.4 Analysis by Geography
    21 Supplier Landscape
    21.1 Market Share by Top 5 Companies
    21.2 AbbVie Inc.
    21.2.1 Financial Analysis
    21.2.2 Product Portfolio
    21.2.3 Demographic Reach and Achievements
    21.2.4 Mergers and Acquisitions
    21.2.5 Certifications
    21.3 Apotex Inc.
    21.3.1 Financial Analysis
    21.3.2 Product Portfolio
    21.3.3 Demographic Reach and Achievements
    21.3.4 Mergers and Acquisitions
    21.3.5 Certifications
    21.4 Amgen Inc.
    21.4.1 Financial Analysis
    21.4.2 Product Portfolio
    21.4.3 Demographic Reach and Achievements
    21.4.4 Mergers and Acquisitions
    21.4.5 Certifications
    21.5 F. Hoffmann-La Roche Ltd.
    21.5.1 Financial Analysis
    21.5.2 Product Portfolio
    21.5.3 Demographic Reach and Achievements
    21.5.4 Mergers and Acquisitions
    21.5.5 Certifications
    21.6 Galapagos NV
    21.6.1 Financial Analysis
    21.6.2 Product Portfolio
    21.6.3 Demographic Reach and Achievements
    21.6.4 Mergers and Acquisitions
    21.6.5 Certifications
    21.7 Johnson & Johnson Services, Inc.
    21.7.1 Financial Analysis
    21.7.2 Product Portfolio
    21.7.3 Demographic Reach and Achievements
    21.7.4 Mergers and Acquisitions
    21.7.5 Certifications
    21.8 Merck and Co. Inc.
    21.8.1 Financial Analysis
    21.8.2 Product Portfolio
    21.8.3 Demographic Reach and Achievements
    21.8.4 Mergers and Acquisitions
    21.8.5 Certifications
    21.9 Otsuka Holdings Co. Ltd
    21.9.1 Financial Analysis
    21.9.2 Product Portfolio
    21.9.3 Demographic Reach and Achievements
    21.9.4 Mergers and Acquisitions
    21.9.5 Certifications
    21.10 Palladio Biosciences Inc.
    21.10.1 Financial Analysis
    21.10.2 Product Portfolio
    21.10.3 Demographic Reach and Achievements
    21.10.4 Mergers and Acquisitions
    21.10.5 Certifications
    21.11 Regulus Therapeutics
    21.11.1 Financial Analysis
    21.11.2 Product Portfolio
    21.11.3 Demographic Reach and Achievements
    21.11.4 Mergers and Acquisitions
    21.11.5 Certifications
    21.12 Sanofi SA
    21.12.1 Financial Analysis
    21.12.2 Product Portfolio
    21.12.3 Demographic
    21.12.4 Mergers and Acquisitions
    21.12.5 Certifications
    21.13 XORTX Therapeutics Inc
    21.13.1 Financial Analysis
    21.13.2 Product Portfolio
    21.13.3 Demographic Reach and Achievements
    21.13.4 Mergers and Acquisitions
    21.13.5 Certifications
    21.14 Novartis AG
    21.14.1 Financial Analysis
    21.14.2 Product Portfolio
    21.14.3 Demographic Reach and Achievements
    21.14.4 Mergers and Acquisitions
    21.14.5 Certifications
    21.15 Teva Pharmaceutical Industries Ltd.
    21.15.1 Financial Analysis
    21.15.2 Product Portfolio
    21.15.3 Demographic Reach and Achievements
    21.15.4 Mergers and Acquisitions
    21.15.5 Certifications
    21.16 Bayer AG
    21.16.1 Financial Analysis
    21.16.2 Product Portfolio
    21.16.3 Demographic Reach and Achievements
    21.16.4 Mergers and Acquisitions
    21.16.5 Certifications
    22 Polycystic Kidney Disease Drugs Market – Distribution Model (Additional Insight)
    22.1 Overview
    22.2 Potential Distributors
    22.3 Key Parameters for Distribution Partner Assessment
    23 Key Opinion Leaders (KOL) Insights (Additional Insight)
    24 Company Competitiveness Analysis (Additional Insight)
    24.1 Very Small Companies
    24.2 Small Companies
    24.3 Mid-Sized Companies
    24.4 Large Companies
    24.5 Very Large Companies
    25 Payment Methods (Additional Insight)
    25.1 Government Funded
    25.2 Private Insurance
    25.3 Out-of-Pocket
    How Do Licenses Work?
    Head shot

    Questions or Comments?

    Our team has the ability to search within reports to verify it suits your needs. We can also help maximize your budget by finding sections of reports you can purchase.