Farber’s Disease Epidemiology Forecast 2025-2034

Farber’s disease refers to an autosomal recessive lysosomal storage disorder that is caused due to mutations in the ASAH1 gene. This genetic disease is extremely rare and is estimated to have a prevalence of less than 1 in 1,000,000 individuals. Studies show that most of the cases of Farber’s disease are reported from the United States and India.

Farber’s Disease Epidemiology Forecast Report Coverage

Expert Market Research's “Farber’s Disease Epidemiology Forecast Report 2025-2034” offers comprehensive information on the prevalence and demographics of Farber’s disease. It projects the future incidence and prevalence rates of Farber’s disease across various populations. The study covers age and type as major determinants of the Farber’s disease-affected population. The report highlights patterns in the prevalence of Farber’s disease over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of Farber’s disease in the 8 major markets.

Regions Covered

• The United States
• Germany
• France
• Italy
• Spain
• The United Kingdom
• Japan
• India

Farber’s Disease: Disease Overview

Farber's disease occurs due to a deficiency in the enzyme ceramidase which is responsible for breaking down ceramide into sphingosine and fatty acid. This inherited metabolic disorder is characterized by the accumulation of fatty material in the tissues, joints, and nervous system. Common symptoms include developmental delay, small lumps under the skin, hoarse voice, and swollen and painful joints, among others.

Farber’s Disease: Treatment Overview

Currently, there is no specific therapy for the effective treatment of Farber's disease. Symptomatic treatments are available for the patients, based on corticotherapy, analgesics, and plastic surgery. Acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs) are some of the commonly used pain medications for joint pain. Corticosteroids are also used for pain relief. Bone marrow transplants are usually recommended for patients with limited neurological involvement.

Epidemiology

The Farber’s disease epidemiology section offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for Farber’s disease by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for Farber’s disease and their trends. The data is broken down into specific categories, such as the total diagnosed cases across different age groups and patient pools.

• The prevalence of Farber’s disease (also known as ASAH1-related disorders) is estimated to be less than 1 in 1,000,000. Farber’s disease-type 1 is the most common form, type 4 is the most severe form, and type 7 is the least common type of Farber’s disease. Type 1 Farber’s disease is reported to have a life expectancy of about 3 years whereas type 2 and type 3 patients are found to have a longer life expectancy.
• Around 200 cases of Farber disease are estimated to be reported worldwide in published literature, according to the Orphanet.
• As per a case report published in the International Journal of Health Sciences and Research, most children affected by Farber’s disease die by the age of 2 years, often due to lung disease.
• Farber’s disease occurs in both males and females. Children born to parents with the defective gene have a 50% chance of carrying the faulty gene and a 25% chance of inheriting the acid ceramidase deficiency disorder.

Country-wise Farber’s Disease Epidemiology

The Farber’s disease epidemiology data and findings for the United States, EU-4 (Germany, Spain, Italy, France), the United Kingdom, Japan, and India are also provided in the epidemiology section.

The epidemiology of Farber’s disease varies significantly between countries owing to the differences in genetic mutations, the prevalence of consanguineous marriages, and population structure, among others. Studies show that majority of the Farber’s disease cases are reported from the United States and India.

Country Specific Stats:

Country

Prevalence (Unit)

United States

United Kingdom

Germany

Italy

France

Spain

Japan

India

Scope of the Report

• The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of Farber’s disease based on several factors.
• Farber’s Disease Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
• The report helps to identify the patient population, and the unmet needs of Farber’s disease are highlighted along with an assessment of the disease's risk and burden.

Key Questions Answered

• What are the key findings of Farber’s disease epidemiology in the 8 major markets?
• What will be the total number of patients with Farber’s disease across the 8 major markets during the forecast period?
• What was the country-wise prevalence of Farber’s disease in the 8 major markets in the historical period?
• Which country will have the highest number of Farber’s disease patients during the forecast period of 2025-2034?
• Which key factors would influence the shift in the patient population of Farber’s disease during the forecast period of 2025-2034?
• What are the currently available treatments for Farber’s disease?
• What are the disease risks, signs, symptoms, and unmet needs of Farber’s disease?

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