ADME Toxicology Testing Market Report and Forecast 2025-2034

The global ADME toxicology testing market was valued at USD 7.18 Billion in 2024, driven by technological advancements and increased demand for safer drug development across the globe. The market is anticipated to grow at a CAGR of 10.30% during the forecast period of 2025-2034, with the values likely to reach USD 19.14 Billion by 2034.

ADME Toxicology Testing Market Overview

ADME toxicology testing analyzes the absorption, distribution, metabolism, and excretion of a drug, therefore judging the safety profile of that drug. Studies in such cases investigate possible toxic effects so that drug developers produce safer drugs. In the entire process of drug discovery, the demand for drugs is increasing at a very rapid rate. These tests, therefore, ensure that the drugs are safe and effective for use in humans. This demand, especially in the preclinical stages of drug development, is pushing the market for cheaper, more efficient, and more reliable testing in toxicology.

ADME Toxicology Testing Market Growth Drivers

Technological Advancements and Increased Demand for Safer Drug Development to Boost the Market Value

Due to the rapid technological advancements and growing demand for safer drug development, the global market for ADME toxicology testing is growing at an expedited rate. For instance, in September 2024, Emulate Inc. launched Chip-R1 Rigid Chip, an Organ-on-a-Chip model that reduces drug absorption for better accuracy in the tests. The increasing demand for in vitro testing combined with the decreased toxicity of the drug upon administration further drives the market.

ADME Toxicology Testing Market Trends

The market is witnessing several trends and developments to improve the current scenario. Some of the notable trends are as follows:

Integration of AI and Machine Learning

There is a rising application of AI and machine learning in ADME toxicology testing, intended to make more accurate predictions on the outcome of data analysis. The use of these technologies makes predictions highly accurate and accelerates the testing process. Machine learning models can pass through large datasets and pick up patterns that might not be noticed through the traditional testing processes. This makes drug development fast and cost-effective.

Personalized Medicine Preference to Boost ADME Toxicology Testing Market Demand

Personalized medicine is altering the ADME toxicology testing environment. Since drugs are becoming custom-made for individual genetic profiles, there is a great demand for tests that would predict how specific patients might metabolize and respond to a given drug. The platform in ADME testing toward incorporation of genetic data into the testing is improving accuracy and bringing about safer, patient-specific drug therapies.

Miniaturization of Testing Platforms to Impact the ADME Toxicology Testing Market Value

With the advent of lab-on-a-chip technologies, ADME toxicology testing shows a tendency towards miniaturization and automation. These approaches allow for higher throughput and efficient data collection at a lesser cost. Miniaturized platforms can accelerate testing on many compounds within a short time. Miniaturization is a major market trend that allows drug researchers more scalability and flexibility options in developing drugs.

Emphasis on Environmental Toxicology to Boost ADME Toxicology Testing Market Growth

There is also a growing need for environmental toxicology that is pushing ADME toxicology testing into environmental safety testing. Strict regulatory norms are making drug testing for its environmental effect, especially water supplies imperative. This has expanded the scope of ADME, mainly in the formulation of more eco-friendly drug formulations.

ADME Toxicology Testing Market Segmentation

The market report offers a detailed analysis of the market based on the following segments:

Market Breakup by Technology

• Cell Culture Technology
• Molecular Imaging Technology
• High Throughput Technology
• OMICS Technology

Market Breakup by Method

• Cellular Assay
• Biochemical Assay
• In-Silica
• Ex-vivo

Market Breakup by Application

• Systemic Toxicity
• Renal Toxicity
• Hepatotoxicity
• Neurotoxicity
• Others

Market Breakup by End User

• Pharmaceutical Companies
• Biotechnological Companies
• Academic/Research institutes
• Others

Market Breakup by Region

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East and Africa

ADME Toxicology Testing Market Share

Segmentation Based on Application to Witness Substantial Growth

Based on the application, the market is segmented into systemic toxicity, renal toxicity, hepatotoxicity, neurotoxicity, and others. Hepatotoxicity is expected to hold a major share in the market. Liver toxicity has been a significant concern in the drug development process as several drugs have been identified to cause liver damage. The high incidence rate of adverse effects related to the liver is expected to drive the market for hepatotoxicity testing in the forecast period.

ADME Toxicology Testing Market Analysis by Region

The market is divided into regions such as North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. North America is a leading market share holder due to the high development of the healthcare infrastructure, significant investment in pharmaceutical R&D, and strict regulatory standards. Europe follows closely based on research capabilities, drug development activities, and regulatory pressure for the safety of drugs.

Leading Players in the ADME Toxicology Testing Market

The key features of the market report comprise patent analysis, grants analysis, funding and investment analysis, and strategic initiatives by the leading players. The major companies in the market are as follows:

Thermo Fisher Scientific Inc.

Thermo Fisher Scientific is among the global market leaders for ADME toxicology testing. Founded in 1956, the company’s headquarters is in Waltham, Massachusetts. Some of its leading products include Gibco hepatocytes, transporters, and many more ADME/Tox assays that have been used to fast-track drug discovery by allowing reliable in vitro models of liver function, toxicity, and metabolic processes.

Charles River Laboratories

Charles River Laboratories, a Delaware corporation incorporated in 1947 and has its headquarters in Wilmington, Massachusetts. They are one of the leading contract research organizations across the globe. Their capabilities include ADME/DMPK studies, pharmacokinetics screening, and toxicology testing. Some of their product lines include high-throughput ADME assays, cytochrome P450 interaction assays, as well as in vivo DMPK studies for drug discovery and development in different industries.

Eurofins Scientific

Eurofins was established in 1997, with its headquarters based in St. Charles, Missouri, and is a prominent ADME and toxicology testing company. Their portfolio consists of more than 500 in vitro assays of small molecules and biologics in terms of ADME properties, hepatotoxicity, nephrotoxicity, and safety pharmacology for drug discovery and development.

Bio-Rad Laboratories, Inc.

Bio-Rad Laboratories is headquartered in Hercules, California, and was established in 1952. It is one of the global leaders in ADME toxicology testing. Its products for screening toxicology tools, such as TOX/See Rapid Urine Drug Screen Tests, test for multiple drugs and their metabolites in human urine and yield quick, accurate results for toxicology applications.

Other key players in the market include Covance (Labcorp Drug Development), Sekisui XenoTech, LLC, Cyprotex (An Evotec Company), Promega Corporation, Agilent Technologies, Inc., and GE Healthcare (Cytiva).

Key Questions Answered in the ADME Toxicology Testing Market Report

• What was the ADME toxicology testing market value in 2024?
• What is the ADME toxicology testing market forecast outlook for 2025-2034?
• What are the regional markets covered in the EMR report?
• What is the market segmentation based on technology?
• What is the market segmentation based on the method?
• What is the market breakup based on application?
• What is the market breakup based on the end user?
• What major factors aid the ADME toxicology testing market demand?
• How has the market performed so far and how is it anticipated to perform in the coming years?
• What are the major drivers, opportunities, and restraints in the market?
• What are the major trends influencing the market?
• Which regional market is expected to dominate the market share in the forecast period?
• Which country is likely to experience elevated growth during the forecast period?
• Who are the key players involved in the ADME toxicology testing market?
• What are the current unmet needs and challenges in the market?
• How are partnerships, collaborations, mergers, and acquisitions among the key market players shaping the market dynamics?

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