
Wet Age-Related Macular Degeneration (Wet-AMD)- Pipeline Insight, 2025
Description
DelveInsight’s, “Wet Age-Related Macular Degeneration (Wet-AMD)- Pipeline Insight, 2025” report provides comprehensive insights about 60+ companies and 70+ pipeline drugs in Wet Age-Related Macular Degeneration (Wet-AMD) pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
Wet Age-Related Macular Degeneration (Wet-AMD): Overview
Wet Age-related Macular Degeneration (AMD) is a chronic eye disease that affects the macula, the central part of the retina responsible for sharp, detailed vision. It is a more severe form of AMD compared to the dry type and progresses rapidly, leading to significant vision loss if untreated. Wet AMD occurs when abnormal blood vessels grow under the macula, leaking blood or fluid, which disrupts retinal function and causes scarring. This condition primarily affects older adults, usually over the age of 50, and is a leading cause of central vision loss in this age group.
Wet AMD typically begins with blurred or distorted central vision, making it difficult to read, recognize faces, or perform tasks requiring precision. Straight lines may appear wavy (metamorphopsia), and dark or empty spots (scotomas) can develop in the central vision field. Symptoms often appear suddenly and worsen quickly. Peripheral vision is usually unaffected, allowing patients to retain some degree of sight.
Wet AMD arises from abnormal angiogenesis (blood vessel growth) under the retina, often triggered by the overproduction of vascular endothelial growth factor (VEGF). While the exact cause is unknown, risk factors include aging, genetics, smoking, obesity, high blood pressure, and a diet low in antioxidants. Environmental factors, such as prolonged exposure to ultraviolet (UV) light, may also contribute to retinal damage.
Diagnosis of wet AMD involves a comprehensive eye examination, including visual acuity tests and dilation to assess the retina. Optical coherence tomography (OCT) is commonly used to provide detailed cross-sectional images of the retina, highlighting fluid accumulation or swelling. Fluorescein angiography may also be performed, where a dye is injected into the bloodstream to map abnormal blood vessels in the retina.
The primary treatment for wet AMD is intravitreal injection of anti-VEGF medications, such as ranibizumab, aflibercept, or bevacizumab, which block the growth of abnormal blood vessels and reduce fluid leakage. Regular injections are often required to maintain vision. Photodynamic therapy (PDT) with verteporfin is another option, particularly for patients who cannot tolerate anti-VEGF treatment. In advanced cases, low-vision aids and rehabilitation may help patients adapt to vision loss. Lifestyle modifications, such as smoking cessation, maintaining a healthy diet rich in leafy greens and omega-3 fatty acids, and managing cardiovascular risk factors, are crucial in managing disease progression.
""Wet Age-Related Macular Degeneration (Wet-AMD)- Pipeline Insight, 2025"" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Wet Age-Related Macular Degeneration (Wet-AMD) pipeline landscape is provided which includes the disease overview and Wet Age-Related Macular Degeneration (Wet-AMD) treatment guidelines. The assessment part of the report embraces, in depth Wet Age-Related Macular Degeneration (Wet-AMD) commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Wet Age-Related Macular Degeneration (Wet-AMD) collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
This segment of the Wet Age-Related Macular Degeneration (Wet-AMD) report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, II/III I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Wet Age-Related Macular Degeneration (Wet-AMD) Emerging Drugs
Further product details are provided in the report……..
Wet Age-Related Macular Degeneration (Wet-AMD): Therapeutic Assessment
This segment of the report provides insights about the different Wet Age-Related Macular Degeneration (Wet-AMD) drugs segregated based on following parameters that define the scope of the report, such as:
Wet Age-Related Macular Degeneration (Wet-AMD): Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Wet Age-Related Macular Degeneration (Wet-AMD) therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Wet Age-Related Macular Degeneration (Wet-AMD) drugs.
Wet Age-Related Macular Degeneration (Wet-AMD) Report Insights
Current Treatment Scenario and Emerging Therapies:
Please Note: It will take 3-4 business days to complete the report upon order confirmation.
Geography Covered
- Global coverage
Wet Age-Related Macular Degeneration (Wet-AMD): Overview
Wet Age-related Macular Degeneration (AMD) is a chronic eye disease that affects the macula, the central part of the retina responsible for sharp, detailed vision. It is a more severe form of AMD compared to the dry type and progresses rapidly, leading to significant vision loss if untreated. Wet AMD occurs when abnormal blood vessels grow under the macula, leaking blood or fluid, which disrupts retinal function and causes scarring. This condition primarily affects older adults, usually over the age of 50, and is a leading cause of central vision loss in this age group.
Wet AMD typically begins with blurred or distorted central vision, making it difficult to read, recognize faces, or perform tasks requiring precision. Straight lines may appear wavy (metamorphopsia), and dark or empty spots (scotomas) can develop in the central vision field. Symptoms often appear suddenly and worsen quickly. Peripheral vision is usually unaffected, allowing patients to retain some degree of sight.
Wet AMD arises from abnormal angiogenesis (blood vessel growth) under the retina, often triggered by the overproduction of vascular endothelial growth factor (VEGF). While the exact cause is unknown, risk factors include aging, genetics, smoking, obesity, high blood pressure, and a diet low in antioxidants. Environmental factors, such as prolonged exposure to ultraviolet (UV) light, may also contribute to retinal damage.
Diagnosis of wet AMD involves a comprehensive eye examination, including visual acuity tests and dilation to assess the retina. Optical coherence tomography (OCT) is commonly used to provide detailed cross-sectional images of the retina, highlighting fluid accumulation or swelling. Fluorescein angiography may also be performed, where a dye is injected into the bloodstream to map abnormal blood vessels in the retina.
The primary treatment for wet AMD is intravitreal injection of anti-VEGF medications, such as ranibizumab, aflibercept, or bevacizumab, which block the growth of abnormal blood vessels and reduce fluid leakage. Regular injections are often required to maintain vision. Photodynamic therapy (PDT) with verteporfin is another option, particularly for patients who cannot tolerate anti-VEGF treatment. In advanced cases, low-vision aids and rehabilitation may help patients adapt to vision loss. Lifestyle modifications, such as smoking cessation, maintaining a healthy diet rich in leafy greens and omega-3 fatty acids, and managing cardiovascular risk factors, are crucial in managing disease progression.
""Wet Age-Related Macular Degeneration (Wet-AMD)- Pipeline Insight, 2025"" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Wet Age-Related Macular Degeneration (Wet-AMD) pipeline landscape is provided which includes the disease overview and Wet Age-Related Macular Degeneration (Wet-AMD) treatment guidelines. The assessment part of the report embraces, in depth Wet Age-Related Macular Degeneration (Wet-AMD) commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Wet Age-Related Macular Degeneration (Wet-AMD) collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
- The companies and academics are working to assess challenges and seek opportunities that could influence Wet Age-Related Macular Degeneration (Wet-AMD) R&D. The therapies under development are focused on novel approaches to treat/improve Wet Age-Related Macular Degeneration (Wet-AMD).
This segment of the Wet Age-Related Macular Degeneration (Wet-AMD) report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, II/III I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Wet Age-Related Macular Degeneration (Wet-AMD) Emerging Drugs
- ONS-5010: Outlook Therapeutics
- OPT-302: Opthea
- SYL1801: Sylentis
- BI 836880: Boehringer Ingelheim
Further product details are provided in the report……..
Wet Age-Related Macular Degeneration (Wet-AMD): Therapeutic Assessment
This segment of the report provides insights about the different Wet Age-Related Macular Degeneration (Wet-AMD) drugs segregated based on following parameters that define the scope of the report, such as:
- Major Players in Wet Age-Related Macular Degeneration (Wet-AMD)
- Phases
- Late stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
- Intravenous
- Subcutaneous
- Oral
- Intramuscular
- Molecule Type
- Monoclonal antibody
- Small molecule
- Peptide
- Product Type
Wet Age-Related Macular Degeneration (Wet-AMD): Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Wet Age-Related Macular Degeneration (Wet-AMD) therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Wet Age-Related Macular Degeneration (Wet-AMD) drugs.
Wet Age-Related Macular Degeneration (Wet-AMD) Report Insights
- Wet Age-Related Macular Degeneration (Wet-AMD) Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing Wet Age-Related Macular Degeneration (Wet-AMD) drugs?
- How many Wet Age-Related Macular Degeneration (Wet-AMD) drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Wet Age-Related Macular Degeneration (Wet-AMD)?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Wet Age-Related Macular Degeneration (Wet-AMD) therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Wet Age-Related Macular Degeneration (Wet-AMD) and their status?
- What are the key designations that have been granted to the emerging drugs?
- Outlook Therapeutics
- Opthea
- Sylentis
- Boehringer Ingelheim
- Molecular Partners
- Sam Chun Dang Pharm
- Generium
- Alvotech
- Adverum Biotechnologies
- EyePoint Pharmaceuticals
- 4D Molecular Therapeutics
- OliX Pharmaceuticals
- Kyowa Kirin
- Exonate
- ONS-5010
- OPT-302
- SYL1801
- BI 836880
- Abicipar pegol
- SCD411
- GNR-067
- AVT06
- ADVM-022
- EYP-1901
- 4D-150
- OLX10212
- KHK4951
- EXN 169
Please Note: It will take 3-4 business days to complete the report upon order confirmation.
Table of Contents
280 Pages
- Introduction
- Executive Summary
- Wet Age-Related Macular Degeneration (Wet-AMD): Overview
- Causes
- Pathophysiology
- Signs and Symptoms
- Diagnosis
- Disease Management
- Pipeline Therapeutics
- Comparative Analysis
- Therapeutic Assessment
- Assessment by Product Type
- Assessment by Stage and Product Type
- Assessment by Route of Administration
- Assessment by Stage and Route of Administration
- Assessment by Molecule Type
- Assessment by Stage and Molecule Type
- Wet Age-Related Macular Degeneration (Wet-AMD)– DelveInsight’s Analytical Perspective
- Late Stage Products (Phase III)
- Comparative Analysis
- OPT-302: Opthea
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Mid Stage Products (Phase II)
- Comparative Analysis
- SYL1801: Sylentis
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Early Stage Products (Phase I/II)
- Comparative Analysis
- BI 836880: Boehringer Ingelheim
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Preclinical and Discovery Stage Products
- Comparative Analysis
- Drug Name: Company Name
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Inactive Products
- Comparative Analysis
- Wet Age-Related Macular Degeneration (Wet-AMD) Key Companies
- Wet Age-Related Macular Degeneration (Wet-AMD) Key Products
- Wet Age-Related Macular Degeneration (Wet-AMD)- Unmet Needs
- Wet Age-Related Macular Degeneration (Wet-AMD)- Market Drivers and Barriers
- Wet Age-Related Macular Degeneration (Wet-AMD)- Future Perspectives and Conclusion
- Wet Age-Related Macular Degeneration (Wet-AMD) Analyst Views
- Wet Age-Related Macular Degeneration (Wet-AMD) Key Companies
- Appendix
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