
Pheochromocytoma- Pipeline Insight, 2024
Description
Pheochromocytoma- Pipeline Insight, 2024
DelveInsight’s, “Pheochromocytoma- Pipeline Insight, 2024” report provides comprehensive insights about 3+ companies and 3+ pipeline drugs in Pheochromocytoma pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
- Global coverage
Pheochromocytoma: Overview
Pheochromocytoma is a rare, usually benign tumor that originates in the adrenal medulla, the inner part of the adrenal gland. These tumors produce an excess of catecholamines, such as adrenaline (epinephrine) and noradrenaline (norepinephrine), hormones that are part of the body's stress response system. Although pheochromocytomas are generally non-cancerous, they can cause significant health issues due to the excessive hormone production, which can lead to life-threatening cardiovascular complications. While pheochromocytomas can occur at any age, they are most commonly diagnosed in individuals between 30 and 50 years old. The hallmark symptoms of pheochromocytoma are related to the excessive production of catecholamines. Common signs include high blood pressure (which can be persistent or episodic), severe headaches, sweating, palpitations, and rapid heart rate (tachycardia). Patients may also experience tremors, anxiety, and weight loss. These symptoms can mimic those of other conditions, making pheochromocytoma difficult to diagnose based on clinical presentation alone. In some cases, the tumor can also cause abdominal pain or a feeling of fullness due to its size and location.
The exact cause of pheochromocytoma is often unknown, but genetic factors can play a significant role. Approximately 25-30% of cases are associated with hereditary syndromes such as Multiple Endocrine Neoplasia type 2 (MEN 2), von Hippel-Lindau disease, and neurofibromatosis type 1. The pathophysiology of pheochromocytoma involves the uncontrolled growth of chromaffin cells in the adrenal medulla, which leads to excessive secretion of catecholamines. These hormones increase heart rate and blood pressure, and their overproduction results in the symptoms associated with the condition.
Diagnosing pheochromocytoma involves a combination of biochemical tests and imaging studies. The measurement of plasma free metanephrines or urinary fractionated metanephrines (metabolites of catecholamines) is the primary biochemical test used to confirm excess hormone production. Once biochemical evidence is obtained, imaging studies such as computed tomography (CT) scans or magnetic resonance imaging (MRI) are used to locate the tumor. In some cases, specialized imaging techniques like metaiodobenzylguanidine (MIBG) scintigraphy or positron emission tomography (PET) scans may be necessary to detect extra-adrenal or metastatic tumors.
The primary treatment for pheochromocytoma is surgical removal of the tumor. Before surgery, patients are typically treated with medications to manage their blood pressure and heart rate, including alpha-blockers and beta-blockers, to prevent complications during the procedure. In cases where the tumor is malignant or has spread beyond the adrenal glands, additional treatments such as chemotherapy, radiation therapy, or targeted therapies may be required. Long-term follow-up is essential as recurrence can occur, and ongoing monitoring for hypertension and other symptoms is necessary to ensure patient health and safety.
""Pheochromocytoma- Pipeline Insight, 2024"" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Pheochromocytoma pipeline landscape is provided which includes the disease overview and Pheochromocytoma treatment guidelines. The assessment part of the report embraces, in depth Pheochromocytoma commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Pheochromocytoma collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
- The companies and academics are working to assess challenges and seek opportunities that could influence Pheochromocytoma R&D. The therapies under development are focused on novel approaches to treat/improve Pheochromocytoma.
This segment of the Pheochromocytoma report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Pheochromocytoma Emerging Drugs
- EO2401: Enterome
Further product details are provided in the report……..
Pheochromocytoma: Therapeutic Assessment
This segment of the report provides insights about the different Pheochromocytoma drugs segregated based on following parameters that define the scope of the report, such as:
- Major Players in Pheochromocytoma
- There are approx. 3+ key companies which are developing the therapies for Pheochromocytoma. The companies which have their Pheochromocytoma drug candidates in the most advanced stage, i.e. phase II include, Enterome.
- Phases
- Late stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
- Oral
- Intravenous
- Subcutaneous
- Parenteral
- Topical
- Molecule Type
- Recombinant fusion proteins
- Small molecule
- Monoclonal antibody
- Peptide
- Polymer
- Gene therapy
- Product Type
Pheochromocytoma: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Pheochromocytoma therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Pheochromocytoma drugs.
Pheochromocytoma Report Insights
- Pheochromocytoma Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing Pheochromocytoma drugs?
- How many Pheochromocytoma drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Pheochromocytoma?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Pheochromocytoma therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Pheochromocytoma and their status?
- What are the key designations that have been granted to the emerging drugs?
- Enterome
- Perspective Therapeutics
- EO2401
- VMT-𝛼-NET
Table of Contents
60 Pages
- Introduction
- Executive Summary
- Pheochromocytoma: Overview
- Causes
- Pathophysiology
- Signs and Symptoms
- Diagnosis
- Disease Management
- Pipeline Therapeutics
- Comparative Analysis
- Therapeutic Assessment
- Assessment by Product Type
- Assessment by Stage and Product Type
- Assessment by Route of Administration
- Assessment by Stage and Route of Administration
- Assessment by Molecule Type
- Assessment by Stage and Molecule Type
- Pheochromocytoma– DelveInsight’s Analytical Perspective
- Late Stage Products (Phase III)
- Comparative Analysis
- Drug Name: Company Name
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Mid Stage Products (Phase II)
- Comparative Analysis
- EO2401: Enterome
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Early Stage Products (Phase I/II)
- Comparative Analysis
- Drug Name: Company Name
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Preclinical and Discovery Stage Products
- Comparative Analysis
- Drug Name: Company Name
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Inactive Products
- Comparative Analysis
- Pheochromocytoma Key Companies
- Pheochromocytoma Key Products
- Pheochromocytoma- Unmet Needs
- Pheochromocytoma- Market Drivers and Barriers
- Pheochromocytoma- Future Perspectives and Conclusion
- Pheochromocytoma Analyst Views
- Pheochromocytoma Key Companies
- Appendix
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