
Hypertension - Pipeline Insight, 2025
Description
DelveInsight’s, “Hypertension - Pipeline Insight, 2025” report provides comprehensive insights about 80+ companies and 100+ pipeline drugs in Hypertension pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
Hypertension: Overview
Hypertension, commonly known as high blood pressure, is a chronic medical condition characterized by elevated pressure in the arteries, which can lead to serious health complications if left untreated. It is classified into primary hypertension, which has no identifiable cause and often develops gradually over many years, and secondary hypertension, which results from an underlying condition, such as kidney disease or hormonal disorders. Hypertension is a major risk factor for cardiovascular diseases, including heart attack and stroke, as well as kidney damage and vision loss. Hypertension, often referred to as the ""silent killer,"" may not present noticeable signs or symptoms, particularly in its early stages, which makes regular monitoring essential. When symptoms do occur, they can include headaches, dizziness, shortness of breath, nosebleeds, and palpitations. In severe cases, individuals may experience blurred vision, chest pain, or fatigue, indicating potential damage to the heart or other organs. It's important to note that many people with hypertension may remain asymptomatic for years, underscoring the need for routine blood pressure checks to detect the condition early and prevent serious health complications.
The pathology of hypertension involves complex interactions between genetic, environmental, and physiological factors that lead to sustained elevations in arterial blood pressure. Central to this process is the dysfunction of the vascular system, particularly the endothelium, which regulates vascular tone and blood flow. In hypertension, factors such as oxidative stress, inflammation, and abnormal production of vasoactive substances (e.g., endothelin and nitric oxide) contribute to endothelial dysfunction and increased vascular resistance. Additionally, neurohumoral mechanisms, including the renin-angiotensin-aldosterone system (RAAS) and sympathetic nervous system activation, play crucial roles in promoting vasoconstriction and fluid retention.
The treatment of hypertension typically involves a multifaceted approach, combining lifestyle modifications and pharmacological interventions to effectively manage blood pressure levels and reduce the risk of cardiovascular complications. Lifestyle changes, such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and low-fat dairy (e.g., the DASH diet), maintaining a healthy weight, engaging in regular physical activity, and limiting alcohol intake and sodium consumption, are essential first steps.
""Hypertension- Pipeline Insight, 2025"" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Hypertension pipeline landscape is provided which includes the disease overview and Hypertension treatment guidelines. The assessment part of the report embraces, in depth Hypertension commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Hypertension collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
This segment of the Hypertension report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Hypertension Emerging Drugs
Further product details are provided in the report……..
Hypertension: Therapeutic Assessment
This segment of the report provides insights about the different Hypertension drugs segregated based on following parameters that define the scope of the report, such as:
Hypertension: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Hypertension therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Hypertension drugs.
Hypertension Report Insights
Current Treatment Scenario and Emerging Therapies:
Please Note: It will take 4-5 business days to complete the report upon order confirmation.
Geography Covered
- Global coverage
Hypertension: Overview
Hypertension, commonly known as high blood pressure, is a chronic medical condition characterized by elevated pressure in the arteries, which can lead to serious health complications if left untreated. It is classified into primary hypertension, which has no identifiable cause and often develops gradually over many years, and secondary hypertension, which results from an underlying condition, such as kidney disease or hormonal disorders. Hypertension is a major risk factor for cardiovascular diseases, including heart attack and stroke, as well as kidney damage and vision loss. Hypertension, often referred to as the ""silent killer,"" may not present noticeable signs or symptoms, particularly in its early stages, which makes regular monitoring essential. When symptoms do occur, they can include headaches, dizziness, shortness of breath, nosebleeds, and palpitations. In severe cases, individuals may experience blurred vision, chest pain, or fatigue, indicating potential damage to the heart or other organs. It's important to note that many people with hypertension may remain asymptomatic for years, underscoring the need for routine blood pressure checks to detect the condition early and prevent serious health complications.
The pathology of hypertension involves complex interactions between genetic, environmental, and physiological factors that lead to sustained elevations in arterial blood pressure. Central to this process is the dysfunction of the vascular system, particularly the endothelium, which regulates vascular tone and blood flow. In hypertension, factors such as oxidative stress, inflammation, and abnormal production of vasoactive substances (e.g., endothelin and nitric oxide) contribute to endothelial dysfunction and increased vascular resistance. Additionally, neurohumoral mechanisms, including the renin-angiotensin-aldosterone system (RAAS) and sympathetic nervous system activation, play crucial roles in promoting vasoconstriction and fluid retention.
The treatment of hypertension typically involves a multifaceted approach, combining lifestyle modifications and pharmacological interventions to effectively manage blood pressure levels and reduce the risk of cardiovascular complications. Lifestyle changes, such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and low-fat dairy (e.g., the DASH diet), maintaining a healthy weight, engaging in regular physical activity, and limiting alcohol intake and sodium consumption, are essential first steps.
""Hypertension- Pipeline Insight, 2025"" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Hypertension pipeline landscape is provided which includes the disease overview and Hypertension treatment guidelines. The assessment part of the report embraces, in depth Hypertension commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Hypertension collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
- The companies and academics are working to assess challenges and seek opportunities that could influence Hypertension R&D. The therapies under development are focused on novel approaches to treat/improve Hypertension.
This segment of the Hypertension report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Hypertension Emerging Drugs
- Seralutinib: Gossamer Bio
- AD-209: Addpharma Inc.
- Zilebesiran: Alnylam Therapeutics
- LAM-001: ORPHAI THERAPEUTICS
- HS135: 35Pharma Inc.
Further product details are provided in the report……..
Hypertension: Therapeutic Assessment
This segment of the report provides insights about the different Hypertension drugs segregated based on following parameters that define the scope of the report, such as:
- Major Players in Hypertension
- There are approx. 80+ key companies which are developing the therapies for Hypertension. The companies which have their Hypertension drug candidates in the most advanced stage, i.e. Phase III include, Gossamer Bio and Addpharma Inc.
- Phases
- Late stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
- Oral
- Intravenous
- Subcutaneous
- Parenteral
- Topical
- Molecule Type
- Recombinant fusion proteins
- Small molecule
- Monoclonal antibody
- Peptide
- Polymer
- Gene therapy
- Product Type
Hypertension: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Hypertension therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Hypertension drugs.
Hypertension Report Insights
- Hypertension Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing Hypertension drugs?
- How many Hypertension drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Hypertension?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Hypertension therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Hypertension and their status?
- What are the key designations that have been granted to the emerging drugs?
- Gossamer Bio
- Addpharma Inc.
- Insmed Incorporated
- Alnylam Pharmaceuticals
- 35Pharma Inc
- Pfizer
- Pharmosa Biopharm Inc.
- Guangzhou Magpie Pharmaceuticals Co., Ltd.
- Suzhou Sanegene Bio Inc.
- JW Pharmaceutical
- Seralutinib
- AD-209
- Treprostinil Palmitil
- Zilebesiran
- HS135
- PF-07868489
- L608
- MN-08
- SGB-3908
- JW0104
Please Note: It will take 4-5 business days to complete the report upon order confirmation.
Table of Contents
240 Pages
- Introduction
- Executive Summary
- Hypertension: Overview
- Introduction
- Causes
- Pathophysiology
- Signs and Symptoms
- Diagnosis
- Treatment
- Pipeline Therapeutics
- Comparative Analysis
- Therapeutic Assessment
- Assessment by Product Type
- Assessment by Stage and Product Type
- Assessment by Route of Administration
- Assessment by Stage and Route of Administration
- Assessment by Molecule Type
- Assessment by Stage and Molecule Type
- Hypertension– DelveInsight’s Analytical Perspective
- Late Stage Products (Phase III)
- Comparative Analysis
- Seralutinib: Gossamer Bio
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Mid Stage Products (Phase II)
- Comparative Analysis
- Zilebesiran: Alnylam Therapeutics
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Early Stage Products (Phase I)
- Comparative Analysis
- HS135: 35Pharma Inc.
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Preclinical and Discovery Stage Products
- Comparative Analysis
- Drug name: Company name
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Inactive Products
- Comparative Analysis
- Hypertension Key Companies
- Hypertension Key Products
- Hypertension- Unmet Needs
- Hypertension- Market Drivers and Barriers
- Hypertension- Future Perspectives and Conclusion
- Hypertension Analyst Views
- Hypertension Key Companies
- Appendix
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