
Catheter-related bloodstream infection (CRBSI) - Pipeline Insight, 2025
Description
DelveInsight’s, “Catheter-related Bloodstream Infection -Pipeline Insight, 2025,” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in Catheter-related Bloodstream Infection pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
Catheter-related Bloodstream Infection: Overview
Catheter-related bloodstream infection (CRBSI) is defined as the presence of bacteremia originating from an intravenous catheter. It is one of the most frequent, lethal, and costly complications of central venous catheterization and also the most common cause of nosocomial bacteremia. Intravascular catheters are integral to the modern practices and are inserted in critically-ill patients for the administration of fluids, blood products, medication, nutritional solutions, and for hemodynamic monitoring. Central venous catheters (CVCs) pose a greater risk of device-related infections than any other types of medical device and are major causes of morbidity and mortality. They are also the main source of bacteremia and septicemia in hospitalized patients. Majority of CRBSIs are associated with CVCs and in prospective studies, the relative risk for CRBSI is up to 64 times greater with CVCs than with peripheral venous catheters.
Symptoms
The diagnosis of Catheter-related bloodstream infection is often suspected clinically in a patient using a CVC who presents with fever or chills, unexplained hypotension, and no other localizing sign.[19,20] Mild symptoms include malaise and nausea, and severe symptoms include high fever with rigors, hypotension, vomiting, and changes in mental status in the setting of a normal catheter exit site or tunnel, on physical examination.
Diagnosis
The diagnosis of Catheter-related bloodstream infection requires a positive culture of blood from a peripheral vein and clear evidence that the catheter is the source. Catheter-related bloodstream infection can be diagnosed when colony counts are at least 3-fold higher in cultures of blood obtained via the CVC than in cultures of blood taken from a peripheral vein. If a blood sample cannot be drawn from a peripheral vein, it is recommended that 2 blood samples should be drawn through different catheter lumens, and the colony count for the blood sample drawn through one lumen is at least 3-fold greater than the colony count for the blood sample obtained from the second lumen should be considered to indicate possible CRBSI.
Treatment
Catheters should be removed from patients with Catheter-related bloodstream infection associated with any local or systemic inflammation or immune-compromised condition. Antibiotic therapy for catheter-related infection is often initiated empirically. Recurrent bacteremia after parenteral therapy is more likely to occur if that therapy is administered through a retained catheter than if the catheter is removed. Antibiotic lock therapy for CRBSI is used in conjunction with systemic antibiotic therapy and involves installing a high concentration of an antibiotic, to which the causative microbe is susceptible in the catheter lumen.
Catheter-related Bloodstream Infection Emerging Drugs Chapters
This segment of the Catheter-related Bloodstream Infection report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Catheter-related Bloodstream Infection Emerging Drugs
Further product details are provided in the report……..
Catheter-related Bloodstream Infection: Therapeutic Assessment
This segment of the report provides insights about the different Catheter-related Bloodstream Infection drugs segregated based on following parameters that define the scope of the report, such as:
Phases
DelveInsight’s report covers around 5+ products under different phases of clinical development like
Catheter-related Bloodstream Infection: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Catheter-related Bloodstream Infection therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Catheter-related Bloodstream Infection drugs.
Report Highlights
Catheter-related Bloodstream Infection Report Insights
Current Treatment Scenario and Emerging Therapies:
Geography Covered
- Global coverage
Catheter-related Bloodstream Infection: Overview
Catheter-related bloodstream infection (CRBSI) is defined as the presence of bacteremia originating from an intravenous catheter. It is one of the most frequent, lethal, and costly complications of central venous catheterization and also the most common cause of nosocomial bacteremia. Intravascular catheters are integral to the modern practices and are inserted in critically-ill patients for the administration of fluids, blood products, medication, nutritional solutions, and for hemodynamic monitoring. Central venous catheters (CVCs) pose a greater risk of device-related infections than any other types of medical device and are major causes of morbidity and mortality. They are also the main source of bacteremia and septicemia in hospitalized patients. Majority of CRBSIs are associated with CVCs and in prospective studies, the relative risk for CRBSI is up to 64 times greater with CVCs than with peripheral venous catheters.
Symptoms
The diagnosis of Catheter-related bloodstream infection is often suspected clinically in a patient using a CVC who presents with fever or chills, unexplained hypotension, and no other localizing sign.[19,20] Mild symptoms include malaise and nausea, and severe symptoms include high fever with rigors, hypotension, vomiting, and changes in mental status in the setting of a normal catheter exit site or tunnel, on physical examination.
Diagnosis
The diagnosis of Catheter-related bloodstream infection requires a positive culture of blood from a peripheral vein and clear evidence that the catheter is the source. Catheter-related bloodstream infection can be diagnosed when colony counts are at least 3-fold higher in cultures of blood obtained via the CVC than in cultures of blood taken from a peripheral vein. If a blood sample cannot be drawn from a peripheral vein, it is recommended that 2 blood samples should be drawn through different catheter lumens, and the colony count for the blood sample drawn through one lumen is at least 3-fold greater than the colony count for the blood sample obtained from the second lumen should be considered to indicate possible CRBSI.
Treatment
Catheters should be removed from patients with Catheter-related bloodstream infection associated with any local or systemic inflammation or immune-compromised condition. Antibiotic therapy for catheter-related infection is often initiated empirically. Recurrent bacteremia after parenteral therapy is more likely to occur if that therapy is administered through a retained catheter than if the catheter is removed. Antibiotic lock therapy for CRBSI is used in conjunction with systemic antibiotic therapy and involves installing a high concentration of an antibiotic, to which the causative microbe is susceptible in the catheter lumen.
Catheter-related Bloodstream Infection Emerging Drugs Chapters
This segment of the Catheter-related Bloodstream Infection report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Catheter-related Bloodstream Infection Emerging Drugs
- Mino-Lok: Leonard-Meron Biosciences, Inc.
Further product details are provided in the report……..
Catheter-related Bloodstream Infection: Therapeutic Assessment
This segment of the report provides insights about the different Catheter-related Bloodstream Infection drugs segregated based on following parameters that define the scope of the report, such as:
- Major Players in Catheter-related Bloodstream Infection
Phases
DelveInsight’s report covers around 5+ products under different phases of clinical development like
- Late-stage products (Phase II and Phase II/III)
- Mid-stage products (Phase II and Phase II/III)
- Early-stage products (Phase I/II and Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
- Oral
- Intravenous
- Molecule Type
- Small molecules
- Proteins and Peptide
- Product Type
Catheter-related Bloodstream Infection: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Catheter-related Bloodstream Infection therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Catheter-related Bloodstream Infection drugs.
Report Highlights
- The companies and academics are working to assess challenges and seek opportunities that could influence Catheter-related Bloodstream Infection R&D. The therapies under development are focused on novel approaches to treat/improve Catheter-related Bloodstream Infection.
- June 2020: New therapy reduces chronic low back pain in large international study
- June 2020: Relievant Announces Publication of 5-Year Data Demonstrating Long Term Clinical Benefits of the Intracept Procedure in Chronic Low Back Pain Patients
Catheter-related Bloodstream Infection Report Insights
- Catheter-related Bloodstream Infection Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing Catheter-related Bloodstream Infection drugs?
- How many Catheter-related Bloodstream Infection drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Catheter-related Bloodstream Infection?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Catheter-related Bloodstream Infection therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Catheter-related Bloodstream Infection and their status?
- What are the key designations that have been granted to the emerging drugs?
- Leonard-Meron Biosciences, Inc.
- Mino-Lok
Table of Contents
40 Pages
- Introduction
- Executive Summary
- Catheter-related Bloodstream Infection: Overview
- Causes
- Mechanism of Action
- Signs and Symptoms
- Diagnosis
- Disease Management
- Pipeline Therapeutics
- Comparative Analysis
- Therapeutic Assessment
- Assessment by Product Type
- Assessment by Stage and Product Type
- Assessment by Route of Administration
- Assessment by Stage and Route of Administration
- Assessment by Molecule Type
- Assessment by Stage and Molecule Type
- Catheter-related Bloodstream Infection – DelveInsight’s Analytical Perspective
- In-depth Commercial Assessment
- Catheter-related Bloodstream Infection companies’ collaborations, Licensing, Acquisition -Deal Value Trends
- Catheter-related Bloodstream Infection Collaboration Deals
- Company-Company Collaborations (Licensing / Partnering) Analysis
- Company-University Collaborations (Licensing / Partnering) Analysis
- Late Stage Products (Phase III)
- Comparative Analysis
- Mino-Lok: Leonard-Meron Biosciences, Inc.
- Product Description
- Research and Development
- Product Development Activities
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Catheter-related Bloodstream Infection Key Companies
- Catheter-related Bloodstream Infection Key Products
- Catheter-related Bloodstream Infection- Unmet Needs
- Catheter-related Bloodstream Infection- Market Drivers and Barriers
- Catheter-related Bloodstream Infection- Future Perspectives and Conclusion
- Catheter-related Bloodstream Infection Analyst Views
- Catheter-related Bloodstream Infection Key Companies
- Appendix
Pricing
Currency Rates
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