Acromegaly- Pipeline Insight, 2025
Description
DelveInsight’s, “Acromegaly- Pipeline Insight, 2025,”report provides comprehensive insights about 12+ companies and 13+ pipeline drugs in Acromegaly pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
Acromegaly: Overview
Acromegaly is a rare endocrine disorder caused by a benign tumor of pituitary gland that results in over-secretion of growth hormone (GH.) that in turn causes abnormal increase in insulin-like growth factor-1 (IGF-1). Most pituitary adenomas are slow growing and benign. Symptoms include body odor, easy fatigue, headache, large feet, excessive height, swelling of the bony areas around a joint, widely spaced teeth, and sleep apnea. In adults, too much of this hormone causes bones, cartilage, body organs, and other tissues to increase in size. Common changes in appearance include enlarged or swollen nose, ears, hands, and feet and jaw. The medical complications include cardiovascular disease like hypertension, cardiomyopathy, and diabetes mellitus etc.
Because acromegaly progresses slowly, early signs may not be obvious for years. Sometimes, people notice the physical changes only by comparing old photos with newer ones. Overall, acromegaly signs and symptoms tend to vary from one person to another and may include any of the following: enlarged hands and feet, enlarged facial features, including the facial bones, lips, nose, and tongue, coarse, oily, thickened skin, excessive sweating, and body odor. Acromegaly is a rare disorder caused by excess levels of growth hormone (GH) in the body. In most patients, excess levels of GH are caused by a benign (noncancerous) tumor in the pituitary gland (pituitary adenoma). Most adenomas form from the excessive growth of a pituitary cell called a somatotrope cell (the pituitary cell that normally secretes GH). In most patients, the disease is sporadic and not due to an inherited genetic mutation.
The disease can be diagnosed by measuring IGF-1 levels in blood the elevated IGF-1 level suggests acromegaly second method is by growth hormone suppression test it is the best method to diagnose acromegaly and lastly imaging by doing MRI to help identify the location and size of a tumor in pituitary gland.
Treatment options depends on the location and size of tumor, the severity of symptoms, and age and overall health of the person. It includes surgery options, medications as well as radiation treatments. The medication options developed for the treatment of acromegaly generally focus on drugs that reduce growth hormone production (somatostatin analogues) somatostatin works against (inhibits) GH production like octreotide (Sandostatin) and lanreotide (Somatuline Depot), drugs that lower hormone levels (dopamine agonists) like cabergoline and bromocriptine (Parlodel) that may help lower levels of GH and IGF-1 and also drugs to block the action of GH (growth hormone antagonist).
""Acromegaly- Pipeline Insight, 2025"" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Acromegaly pipeline landscape is provided which includes the disease overview and Acromegaly treatment guidelines. The assessment part of the report embraces, in depth Acromegaly commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Acromegaly collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
This segment of the Acromegaly report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Acromegaly Emerging Drugs
Further product details are provided in the report……..
Acromegaly: Therapeutic Assessment
This segment of the report provides insights about the different Acromegaly drugs segregated based on following parameters that define the scope of the report, such as:
Acromegaly: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Acromegaly therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Acromegaly drugs.
Acromegaly Report Insights
Current Treatment Scenario and Emerging Therapies:
Geography Covered
- Global coverage
Acromegaly: Overview
Acromegaly is a rare endocrine disorder caused by a benign tumor of pituitary gland that results in over-secretion of growth hormone (GH.) that in turn causes abnormal increase in insulin-like growth factor-1 (IGF-1). Most pituitary adenomas are slow growing and benign. Symptoms include body odor, easy fatigue, headache, large feet, excessive height, swelling of the bony areas around a joint, widely spaced teeth, and sleep apnea. In adults, too much of this hormone causes bones, cartilage, body organs, and other tissues to increase in size. Common changes in appearance include enlarged or swollen nose, ears, hands, and feet and jaw. The medical complications include cardiovascular disease like hypertension, cardiomyopathy, and diabetes mellitus etc.
Because acromegaly progresses slowly, early signs may not be obvious for years. Sometimes, people notice the physical changes only by comparing old photos with newer ones. Overall, acromegaly signs and symptoms tend to vary from one person to another and may include any of the following: enlarged hands and feet, enlarged facial features, including the facial bones, lips, nose, and tongue, coarse, oily, thickened skin, excessive sweating, and body odor. Acromegaly is a rare disorder caused by excess levels of growth hormone (GH) in the body. In most patients, excess levels of GH are caused by a benign (noncancerous) tumor in the pituitary gland (pituitary adenoma). Most adenomas form from the excessive growth of a pituitary cell called a somatotrope cell (the pituitary cell that normally secretes GH). In most patients, the disease is sporadic and not due to an inherited genetic mutation.
The disease can be diagnosed by measuring IGF-1 levels in blood the elevated IGF-1 level suggests acromegaly second method is by growth hormone suppression test it is the best method to diagnose acromegaly and lastly imaging by doing MRI to help identify the location and size of a tumor in pituitary gland.
Treatment options depends on the location and size of tumor, the severity of symptoms, and age and overall health of the person. It includes surgery options, medications as well as radiation treatments. The medication options developed for the treatment of acromegaly generally focus on drugs that reduce growth hormone production (somatostatin analogues) somatostatin works against (inhibits) GH production like octreotide (Sandostatin) and lanreotide (Somatuline Depot), drugs that lower hormone levels (dopamine agonists) like cabergoline and bromocriptine (Parlodel) that may help lower levels of GH and IGF-1 and also drugs to block the action of GH (growth hormone antagonist).
""Acromegaly- Pipeline Insight, 2025"" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Acromegaly pipeline landscape is provided which includes the disease overview and Acromegaly treatment guidelines. The assessment part of the report embraces, in depth Acromegaly commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Acromegaly collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
- The companies and academics are working to assess challenges and seek opportunities that could influence Acromegaly R&D. The therapies under development are focused on novel approaches to treat/improve Acromegaly.
This segment of the Acromegaly report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Acromegaly Emerging Drugs
- Paltusotine: Crinetics Pharmaceuticals Inc.
- AZP-3813: Amolyt Pharma
Further product details are provided in the report……..
Acromegaly: Therapeutic Assessment
This segment of the report provides insights about the different Acromegaly drugs segregated based on following parameters that define the scope of the report, such as:
- Major Players in Acromegaly
- Phases
- Late stage products (Phase II)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
- Oral
- Parenteral
- intravenous
- Subcutaneous
- Topical.
- Molecule Type
- Monoclonal Antibody
- Peptides
- Polymer
- Small molecule
- Gene therapy
- Product Type
Acromegaly: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Acromegaly therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Acromegaly drugs.
Acromegaly Report Insights
- Acromegaly Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing Acromegaly drugs?
- How many Acromegaly drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Acromegaly?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Acromegaly therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Acromegaly and their status?
- What are the key designations that have been granted to the emerging drugs?
- Crinetics Pharmaceuticals Inc.
- Ionis Pharmaceuticals, Inc.
- Amolyt Pharma
- Ipsen
- Strongbridge Biopharma plc
- Amryt Pharma Plc
- Antisense Therapeutics Ltd
- Paltusotine
- IONIS-GHR-LRx
- AZP-3813
- FP-002
- AZP-3800
- AQST-305
- MOD-12014
Table of Contents
60 Pages
- Introduction
- Executive Summary
- Acromegaly: Overview
- Causes
- Pathophysiology
- Signs and Symptoms
- Diagnosis
- Disease Management
- Pipeline Therapeutics
- Comparative Analysis
- Therapeutic Assessment
- Assessment by Product Type
- Assessment by Stage and Product Type
- Assessment by Route of Administration
- Assessment by Stage and Route of Administration
- Assessment by Molecule Type
- Assessment by Stage and Molecule Type
- Late Stage Products (Phase III)
- Comparative Analysis
- Paltusotine: Crinetics Pharmaceuticals Inc.
- Product Description
- Research and Development
- Product Development Activities
- Product Development Activities
- Drug profiles in the detailed report…..
- Mid Stage Products (Phase II)
- Comparative Analysis
- Product Name: Company Name
- Product Description
- Research and Development
- Early Stage Products (Phase I)
- Comparative Analysis
- AZP-3813: Amolyt Pharma
- Product Description
- Research and Development
- Product Developmental Activities
- Inactive Products
- Comparative Analysis
- Acromegaly Key Companies
- Acromegaly Key Products
- Acromegaly- Unmet Needs
- Acromegaly- Market Drivers and Barriers
- Acromegaly- Future Perspectives and Conclusion
- Acromegaly Analyst Views
- Acromegaly Key Companies
- Appendix
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