Global Small Nucleic Acid Drug Competitive Landscape Professional Research Report 2025

Research Summary

Small nucleic acid drugs are a class of therapeutic agents that target specific sequences of RNA or DNA to regulate gene expression and modulate biological processes at the molecular level. These drugs, including antisense oligonucleotides, small interfering RNA (siRNA), and messenger RNA (mRNA) therapeutics, are designed to bind to their target nucleic acids and either block the production of harmful proteins or correct genetic defects. Small nucleic acid drugs have gained significant attention for their potential to treat a wide range of diseases, including genetic disorders, viral infections, and cancer, by precisely targeting the root cause of the disease at the genetic level. These drugs offer a novel and highly specific approach to therapy, with the ability to treat conditions that were previously difficult or impossible to address with traditional small-molecule drugs.

According to DIResearch's in-depth investigation and research, the global Small Nucleic Acid Drug market size was valued at XX Million USD in 2024 and is projected to reach XX Million USD by 2032, with a CAGR of XX% (2025-2032). Notably, the China market has changed rapidly in the past few years. By 2024, China's market size has reached XX Million USD, representing approximately XX% of the global market share. By 2032, it is anticipated to grow further to XX Million USD, contributing XX% to the worldwide market share.

The major global suppliers of Small Nucleic Acid Drug include Sarepta Therapeutics, Ionis Pharmaceuticals, Alnylam, Biogen, Nippon Shinyaku, Sobi, Novartis, Jazz Pharmaceuticals, AstraZeneca, Novo Nordisk, Astellas Pharma, Geron Corporation, CureVac, Regulus Therapeutics, ProQR, Secarna, MiNA Therapeutics, Sylentis, Arrowhead, Silence Therapeutics, etc. The global players competition landscape in this report is divided into three tiers. The first tier comprises global leading enterprises that command a substantial market share, hold a dominant industry position, possess strong competitiveness and influence, and generate significant revenue. The second tier includes companies with a notable market presence and reputation; these firms actively follow industry leaders in product, service, or technological innovation and maintain a moderate revenue scale. The third tier consists of smaller companies with limited market share and lower brand recognition, primarily focused on local markets and generating comparatively lower revenue.

This report studies the market size, price trends and future development prospects of Small Nucleic Acid Drug. Focus on analysing the market share, product portfolio, prices, sales, revenue and gross profit margin of global major suppliers, as well as the market status and trends of different product types and applications in the global Small Nucleic Acid Drug market. The report data covers historical data from 2020 to 2024, based year in 2025 and forecast data from 2026 to 2032.

The regions and countries in the report include North America, Europe, China, APAC (excl. China), Latin America and Middle East and Africa, covering the Small Nucleic Acid Drug market conditions and future development trends of key regions and countries, combined with industry-related policies and the latest technological developments, analyze the development characteristics of Small Nucleic Acid Drug industries in various regions and countries, help companies understand the development characteristics of each region, help companies formulate business strategies, and achieve the ultimate goal of the company's global development strategy.

The data sources of this report mainly include the National Bureau of Statistics, customs databases, industry associations, corporate financial reports, third-party databases, etc. Among them, macroeconomic data mainly comes from the National Bureau of Statistics, International Economic Research Organization; industry statistical data mainly come from industry associations; company data mainly comes from interviews, public information collection, third-party reliable databases, and price data mainly comes from various markets monitoring database.

Global Key Suppliers of Small Nucleic Acid Drug Include:

Sarepta Therapeutics

Ionis Pharmaceuticals

Alnylam

Biogen

Nippon Shinyaku

Sobi

Novartis

Jazz Pharmaceuticals

AstraZeneca

Novo Nordisk

Astellas Pharma

Geron Corporation

CureVac

Regulus Therapeutics

ProQR

Secarna

MiNA Therapeutics

Sylentis

Arrowhead

Silence Therapeutics

Small Nucleic Acid Drug Product Segment Include:

Antisense Oligonucleotides (ASO)

siRNA

Others

Small Nucleic Acid Drug Product Application Include:

Neuromuscular Diseases

hATTR

Others

Chapter Scope

Chapter 1: Product Research Range, Product Types and Applications, Market Overview, Market Situation and Trends

Chapter 2: Global Small Nucleic Acid Drug Industry PESTEL Analysis

Chapter 3: Global Small Nucleic Acid Drug Industry Porter’s Five Forces Analysis

Chapter 4: Global Small Nucleic Acid Drug Major Regional Market Size and Forecast Analysis

Chapter 5: Global Small Nucleic Acid Drug Market Size and Forecast by Type and Application Analysis

Chapter 6: North America Passenger Small Nucleic Acid Drug Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 7: Europe Small Nucleic Acid Drug Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 8: China Small Nucleic Acid Drug Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 9: APAC (Excl. China) Small Nucleic Acid Drug Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 10: Latin America Small Nucleic Acid Drug Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 11: Middle East and Africa Small Nucleic Acid Drug Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 12: Global Small Nucleic Acid Drug Competitive Analysis of Key Suppliers (Revenue, Market Share, Regional Distribution and Industry Concentration)

Chapter 13: Key Company Profiles (Product Portfolio, Revenue and Gross Margin)

Chapter 14: Industrial Chain Analysis, Include Raw Material Suppliers, Distributors and Customers

Chapter 15: Research Findings and Conclusion

Chapter 16: Methodology and Data Sources


1 Small Nucleic Acid Drug Market Overview
1.1 Product Definition and Statistical Scope
1.2 Small Nucleic Acid Drug Product by Type
1.2.1 Antisense Oligonucleotides (ASO)
1.2.2 siRNA
1.2.3 Others
1.3 Small Nucleic Acid Drug Product by Application
1.3.1 Neuromuscular Diseases
1.3.2 hATTR
1.3.3 Others
1.4 Global Small Nucleic Acid Drug Market Size Analysis (2020-2032)
1.5 Small Nucleic Acid Drug Market Development Status and Trends
1.5.1 Small Nucleic Acid Drug Industry Development Status Analysis
1.5.2 Small Nucleic Acid Drug Industry Development Trends Analysis
2 Small Nucleic Acid Drug Market PESTEL Analysis
2.1 Political Factors Analysis
2.2 Economic Factors Analysis
2.3 Social Factors Analysis
2.4 Technological Factors Analysis
2.5 Environmental Factors Analysis
2.6 Legal Factors Analysis
3 Small Nucleic Acid Drug Market Porter's Five Forces Analysis
3.1 Competitive Rivalry
3.2 Threat of New Entrants
3.3 Bargaining Power of Suppliers
3.4 Bargaining Power of Buyers
3.5 Threat of Substitutes
4 Global Small Nucleic Acid Drug Market Analysis by Regions
4.1 Small Nucleic Acid Drug Overall Market: 2024 VS 2025 VS 2032
4.2 Global Small Nucleic Acid Drug Revenue and Forecast Analysis (2020-2032)
4.2.1 Global Small Nucleic Acid Drug Revenue and Market Share by Region (2020-2025)
4.2.2 Global Small Nucleic Acid Drug Revenue Forecast by Region (2026-2032)
5 Global Small Nucleic Acid Drug Market Size by Type and Application
5.1 Global Small Nucleic Acid Drug Market Size by Type (2020-2032)
5.2 Global Small Nucleic Acid Drug Market Size by Application (2020-2032)
6 North America
6.1 North America Small Nucleic Acid Drug Market Size and Growth Rate Analysis (2020-2032)
6.2 North America Key Suppliers Analysis
6.3 North America Small Nucleic Acid Drug Market Size by Type
6.4 North America Small Nucleic Acid Drug Market Size by Application
6.5 North America Small Nucleic Acid Drug Market Size by Country
6.5.1 US
6.5.2 Canada
7 Europe
7.1 Europe Small Nucleic Acid Drug Market Size and Growth Rate Analysis (2020-2032)
7.2 Europe Key Suppliers Analysis
7.3 Europe Small Nucleic Acid Drug Market Size by Type
7.4 Europe Small Nucleic Acid Drug Market Size by Application
7.5 Europe Small Nucleic Acid Drug Market Size by Country
7.5.1 Germany
7.5.2 France
7.5.3 United Kingdom
7.5.4 Italy
7.5.5 Spain
7.5.6 Benelux
8 China
8.1 China Small Nucleic Acid Drug Market Size and Growth Rate Analysis (2020-2032)
8.2 China Key Suppliers Analysis
8.3 China Small Nucleic Acid Drug Market Size by Type
8.4 China Small Nucleic Acid Drug Market Size by Application
9 APAC (excl. China)
9.1 APAC (excl. China) Small Nucleic Acid Drug Market Size and Growth Rate Analysis (2020-2032)
9.2 APAC (excl. China) Key Suppliers Analysis
9.3 APAC (excl. China) Small Nucleic Acid Drug Market Size by Type
9.4 APAC (excl. China) Small Nucleic Acid Drug Market Size by Application
9.5 APAC (excl. China) Small Nucleic Acid Drug Market Size by Country
9.5.1 Japan
9.5.2 South Korea
9.5.3 India
9.5.4 Australia
9.5.5 Southeast Asia
10 Latin America
10.1 Latin America Small Nucleic Acid Drug Market Size and Growth Rate Analysis (2020-2032)
10.2 Latin America Key Suppliers Analysis
10.3 Latin America Small Nucleic Acid Drug Market Size by Type
10.4 Latin America Small Nucleic Acid Drug Market Size by Application
10.5 Latin America Small Nucleic Acid Drug Market Size by Country
10.5.1 Mexico
10.5.2 Brazil
11 Middle East & Africa
11.1 Middle East & Africa Small Nucleic Acid Drug Market Size and Growth Rate Analysis (2020-2032)
11.2 Middle East & Africa Key Suppliers Analysis
11.3 Middle East & Africa Small Nucleic Acid Drug Market Size by Type
11.4 Middle East & Africa Small Nucleic Acid Drug Market Size by Application
11.5 Middle East & Africa Small Nucleic Acid Drug Market Size by Country
11.5.1 Saudi Arabia
11.5.2 South Africa
12 Competition by Suppliers
12.1 Global Small Nucleic Acid Drug Market Revenue by Key Suppliers (2021-2025)
12.2 Small Nucleic Acid Drug Competitive Landscape Analysis and Market Dynamic
12.2.1 Small Nucleic Acid Drug Competitive Landscape Analysis
12.2.2 Global Key Suppliers Headquarter Location and Key Area Sales
12.2.3 Market Dynamic
13 Key Companies Analysis
13.1 Sarepta Therapeutics
13.1.1 Sarepta Therapeutics Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.1.2 Sarepta Therapeutics Small Nucleic Acid Drug Product Portfolio
13.1.3 Sarepta Therapeutics Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.2 Ionis Pharmaceuticals
13.2.1 Ionis Pharmaceuticals Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.2.2 Ionis Pharmaceuticals Small Nucleic Acid Drug Product Portfolio
13.2.3 Ionis Pharmaceuticals Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.3 Alnylam
13.3.1 Alnylam Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.3.2 Alnylam Small Nucleic Acid Drug Product Portfolio
13.3.3 Alnylam Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.4 Biogen
13.4.1 Biogen Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.4.2 Biogen Small Nucleic Acid Drug Product Portfolio
13.4.3 Biogen Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.5 Nippon Shinyaku
13.5.1 Nippon Shinyaku Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.5.2 Nippon Shinyaku Small Nucleic Acid Drug Product Portfolio
13.5.3 Nippon Shinyaku Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.6 Sobi
13.6.1 Sobi Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.6.2 Sobi Small Nucleic Acid Drug Product Portfolio
13.6.3 Sobi Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.7 Novartis
13.7.1 Novartis Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.7.2 Novartis Small Nucleic Acid Drug Product Portfolio
13.7.3 Novartis Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.8 Jazz Pharmaceuticals
13.8.1 Jazz Pharmaceuticals Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.8.2 Jazz Pharmaceuticals Small Nucleic Acid Drug Product Portfolio
13.8.3 Jazz Pharmaceuticals Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.9 AstraZeneca
13.9.1 AstraZeneca Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.9.2 AstraZeneca Small Nucleic Acid Drug Product Portfolio
13.9.3 AstraZeneca Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.10 Novo Nordisk
13.10.1 Novo Nordisk Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.10.2 Novo Nordisk Small Nucleic Acid Drug Product Portfolio
13.10.3 Novo Nordisk Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.11 Astellas Pharma
13.11.1 Astellas Pharma Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.11.2 Astellas Pharma Small Nucleic Acid Drug Product Portfolio
13.11.3 Astellas Pharma Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.12 Geron Corporation
13.12.1 Geron Corporation Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.12.2 Geron Corporation Small Nucleic Acid Drug Product Portfolio
13.12.3 Geron Corporation Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.13 CureVac
13.13.1 CureVac Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.13.2 CureVac Small Nucleic Acid Drug Product Portfolio
13.13.3 CureVac Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.14 Regulus Therapeutics
13.14.1 Regulus Therapeutics Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.14.2 Regulus Therapeutics Small Nucleic Acid Drug Product Portfolio
13.14.3 Regulus Therapeutics Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.15 ProQR
13.15.1 ProQR Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.15.2 ProQR Small Nucleic Acid Drug Product Portfolio
13.15.3 ProQR Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.16 Secarna
13.16.1 Secarna Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.16.2 Secarna Small Nucleic Acid Drug Product Portfolio
13.16.3 Secarna Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.17 MiNA Therapeutics
13.17.1 MiNA Therapeutics Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.17.2 MiNA Therapeutics Small Nucleic Acid Drug Product Portfolio
13.17.3 MiNA Therapeutics Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.18 Sylentis
13.18.1 Sylentis Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.18.2 Sylentis Small Nucleic Acid Drug Product Portfolio
13.18.3 Sylentis Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.19 Arrowhead
13.19.1 Arrowhead Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.19.2 Arrowhead Small Nucleic Acid Drug Product Portfolio
13.19.3 Arrowhead Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
13.20 Silence Therapeutics
13.20.1 Silence Therapeutics Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)
13.20.2 Silence Therapeutics Small Nucleic Acid Drug Product Portfolio
13.20.3 Silence Therapeutics Small Nucleic Acid Drug Market Data Analysis (Revenue, Gross Margin and Market Share) (2021-2025)
14 Industry Chain Analysis
14.1 Small Nucleic Acid Drug Industry Chain Analysis
14.2 Small Nucleic Acid Drug Typical Downstream Customers
14.3 Small Nucleic Acid Drug Sales Channel Analysis
15 Research Findings and Conclusion
16 Methodology and Data Source
16.1 Methodology/Research Approach
16.2 Research Scope
16.3 Benchmarks and Assumptions
16.4 Date Source
16.4.1 Primary Sources
16.4.2 Secondary Sources
16.5 Data Cross Validation
16.6 Disclaimer

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