Global Polymerase Chain Reaction Market - 2021-2028

Global Polymerase Chain Reaction Market - 2021-2028

Market Overview

The global polymerase chain reaction market size was valued at US$ XX million in 2020 and is estimated to reach US$ XX million by 2028, growing at a CAGR of XX % during the forecast period (2021-2028).

Polymerase chain reaction (PCR) is a molecular diagnostic procedure that creates numerous copies of a DNA segment. To generate millions of copies of DNA sequencing precisely, a PCR machine is used to regulate the temperature of the material in an autonomous and pre-programmed operation. This technology detects tuberculosis, AIDS, infections, and Lyme disease by identifying and cultivating disease-causing bacteria. As a result, it has a wide range of applications in life science domains like genetics, biotechnology, molecular biology, drug development, and clinical diagnostics.

Market Dynamics

Advancement in Polymerase Chain Reaction for detecting SARS-CoV-2 is expected to drive market growth.

The novel human coronavirus SARS-CoV-2 (also known as 2019-nCoV) continues to spread worldwide. The most common method for detecting viruses is the real-time reverse transcription-polymerase chain reaction (rRT-PCR). However, possible false-negative and false-positive results can lead to inaccurate conclusions, necessitating improving current procedures. A multiplex rRT-PCR diagnostic technique concurrently targets two viral genes (RdRP and E) and one human gene (RP). The process was investigated using a template of pseudo viral RNA and human target mRNA sequences. In addition, 14 clinical SARS-CoV-2 positive samples are used to confirm the methodology. The findings match those of the CDC-approved Cepheid's Xpert Xpress SARS-CoV-2 diagnostic system (100 percent ). Unlike single gene targeting methodologies, the current approach amplifies two viral areas in the same PCR experiment. As a result, an accurate SARS-CoV-2 diagnostic test was developed, with each run allowing for 91 samples in 96-well plates. SARS-CoV-2 can now be diagnosed using a fast, reliable, and simple rRT-PCR approach, thanks to this strategy. Thus, from the above statements, the market is expected to drive in the forecast period.

Restraint:

The high cost of dPCR instruments implementing MIQE (minimum information for publication of quantitative real-time PCR experiments) criteria may offer a significant challenge for companies in worldwide in the future, lack of awareness in emerging nations, rising concerns about the accuracy and timeliness of RT-PCR results and growth of non-validated home-brew tests and reimbursement issues are few factors due to which the market is expected to get hampered in the forecast period.

COVID-19 Impact Analysis

The COVID-19 pandemic had a positive impact on the market. Clinicians commonly detect viral nucleic acid or protein in respiratory tract specimens to diagnose respiratory infection caused by viruses like SARS-CoV-2. Nucleic acid amplification assays, such as the polymerase chain reaction, and fast antigen-based testing, are the two most commonly used techniques for this. When the COVID-19 pandemic began, reverse-transcriptase PCR tests were the first to be developed and widely deployed. For instance, NAATs such as RT-PCR for SARS-CoV-2 are designed to detect viral RNA. Moreover, the International Atomic Energy Agency (IAEA), in collaboration with the United Nations Food and Agriculture Organization (FAO), is offering technical assistance and expertise to countries that want to use real-time reverse transcription-polymerase chain reaction (real-time RT–PCR), one of the fastest and most accurate laboratory methods for detecting, tracking, and studying the COVID-19 virus. Thus, this is due to boosting the forecast period's polymerase chain reaction market.

Segment Analysis

Real-time PCR Systems segment is expected to hold the largest market share in polymerase chain reaction market

The real-time PCR systems segment is expected to dominate in 2020. The segment benefits because the primary advantage of real-time PCR is identifying amplified fragments during the PCR process. Real-time PCR measures the amount of the product during the exponential phase, whereas standard PCR measures the product during the plateau phase. It is more effective to measure during the exponential phase because measurements taken during the plateau phase do not always clearly indicate the quantity of starting material. Moreover, the advantage of real-time PCR over standard PCR is that the entire process from amplification to analysis is performed in the same tube. This differs from standard PCR, where the PCR product is moved and manipulated into other formats. As a result, there is a decreased possibility of contaminating the product with real-time PCR methods. Thus, from the above statements, it has increased the demand, due to which the market segment is expected to hold the largest market share in the forecast period.

Geographical Analysis

North America region holds the largest market share in the global polymerase chain reaction market

In 2020, North America accounted for the highest revenue share. The increasing prevalence of infectious disease, favorable government initiatives, flexible regulatory guidelines, an increase in the number of diagnostics product launches, and the use of diagnostics to identify COVID-19 in an emergency in the region are some of the factors due to which the market is expected to boost in the forecast period. For instance, COVID-19 cases are increasing rapidly, and the spread of the virus is very rapid, speeding up the transmission. The US remains severely affected by the coronavirus disease 2019 (COVID-19) pandemic, with more than 9 million cases and 230 000 deaths reported in 2020. The increasing count of suspects increases the number of diagnostic tests, boosting the market growth in the country. Moreover, The Applied Biosystem QuantStudio Absolute Q-Digital PCR System, the first fully integrated digital PCR (dPCR) system designed to provide highly accurate and consistent results in genetic analysis and research within 90 minutes, was introduced in October 2021 by Thermo Fisher Scientific, a provider of scientific instrumentation, reagents, and consumables based in the United States.

Additionally, In the United States, there is also a growing trend of genetic engineering and genomic research in academia and the biotechnology industry. The rising demand for targeted and precision medicine for the management of chronic illnesses and the need to understand the genetic and molecular basis of disease are driving the growth of genomic research. Thus, the North American region is expected to hold the largest market share in the forecast period from the above statements.

Competitive Landscape

Major key players in the polymerase chain reaction market are Abbott Laboratories, Agilent Technologies Inc., Thermo Fisher Scientific Inc., BioMerieux SA, Siemens Healthineers , Qiagen , Bio-Rad Laboratories, Inc., F. Hoffmann-La Roche Ltd., Fluidigm Corporation and Cytiva.

Abbott Laboratories:

Overview:

Abbott Laboratories (Abbott) develops, manufactures, and markets diagnostic devices, diabetes care, vision technologies, vascular products, and nutrition and animal health products. The company provides innovative medical devices to fulfill unmet healthcare needs. The company provides drug testing products and solutions through its diagnostics segment. Abbott Vascular, a global leader in the Cervical Cancer Diagnostics medical device industry, provides innovative, minimally invasive and cost-effective products to treat coronary artery disease. The company offers an extensive portfolio of drug-eluting stents, bare-metal stents, coronary guide wires, balloon dilatation catheters, and guiding catheters and accessories. Abbott Laboratories operates its business in over 150 countries worldwide.

Product Portfolio:

ABBOTT REALTIME CMV: The Abbott RealTime CMV assay is an in vitro polymerase chain reaction (PCR) assay for the quantitation of cytomegalovirus (CMV) DNA in human plasma or whole blood.

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Target Audience

Service Providers/ Buyers

Industry Investors/Investment Bankers

Education & Research Institutes

Research Professionals

Emerging Companies

Manufacturers

Market Segmentation

Global Polymerase Chain Reaction Market – By Type

Standard PCR Systems

Digital PCR Systems

Real-time PCR Systems

Global Polymerase Chain Reaction Market – By Product

Instruments

Reagents and Consumables

Software

Global Polymerase Chain Reaction Market – By Indication

Infectious Diseases

Oncology

Genetic Disorders

Others

Global Polymerase Chain Reaction Market – By End user

Hospitals & Clinics

Diagnostic Centers

Pharmaceutical and Biotechnology Industries

Academic and Research Organizations

Others

Global Polymerase Chain Reaction Market - By Region

North America

South America

Europe

Asia

Middle East & Africa