Global Cell Isolation Market- 2020-2027
Global Cell Isolation Market is segmented By Cell Type (Animal Cells, Human Cells, Stem Cells, Differentiated Cells), By Cell Source (Bone Marrow, Adipose Tissue, Cord Blood/Embryonic Stem Cells), By Technique (Surface Marker-Based Cell Isolation, Centrifugation-Based Cell Isolation, Filtration-Based Cell Isolation), By Product (Consumables, Reagents & kits, Disposables, Beads, Instruments, Flow cytometers, Centrifuges, Magnetic-activated cell separator systems, Filtration systems), By Application (Cancer Research, Stem Cell Research, In Vitro Diagnostics, Biomolecule Isolation, Tissue Regeneration, Others), By End-User (Hospitals and Diagnostic Laboratories, Research Laboratories and Institutes, Biotechnology and Biopharmaceutical Companies, Cell Banks, Others), and By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2020-2027
Cell Isolation Market Overview
The Cell Isolation Market is expected to grow at a high CAGR of 16.2 % during the forecasting period (2020-2027).
Cell isolation (or cell separation) is a process used for sorting cells from a heterogeneous group of cells into the specific populations without contamination. This technique helps many cell-based therapies to improve the quality of the treatment. Cell isolation techniques are widely used for biomolecule isolation for the production of vaccines, drugs, antibodies, enzymes, proteins, and other biotechnology products.
Cell Isolation Market Dynamics
The cell isolation market growth is majorly driven by the rising prevalence of chronic diseases with growing geriatric population, technological advancement in cell isolation, increasing demand for biopharmaceuticals, and increasing stem cell research.
As per the World Health Organization (WHO), cancer is the second leading cause of death worldwide and is responsible for around 9.6 million deaths in 2018. Globally, about 1 in 6 deaths is due to cancer. Around 70% of deaths from cancer occur in low- and middle-income countries. In 2019, there are about 1,762,450 cancer cases diagnosed, which is the equivalent of more than 4,800 new cases each day. In addition, there will be approximately 62,930 new cases of female breast carcinoma in situ and 95,830 new cases of melanoma in situ of the skin. By region, cancer incidence is highest in Asia compared to other regions. Contextually, the incidence population of cancers in Asia was 6.67 million in 2012 and is anticipated to reach 10.84 by 2030. The cancer incidence in Asia is higher compared to the cumulative incidence population of all other regions. In terms of growth rate too, the incidence rate of cancers is growing at a notable CAGR of 2.7% in this region. Europe has the second-highest cancer incidence, followed by North America. In terms of the increase in cancer incidence, Europe is anticipated to have the slowest growth in the forecast period. In terms of growth of cancer incidence, Middle and North Africa and South America are considered to the top two regions with CAGR of 3.1% and 2.9%, from 2012 to 2030, respectively. Hence, with the rising prevalence of cancer globally is driving the growth of the cell isolation market.
In addition, rising government funding for cell-based research is also expected to fuel market growth. Researchers use isolated cells to develop new cell therapies and treatments. Several government authorities and organizations have increased their support for the growth of such research activities globally due to rising focus on cell-based research. For instance, in January 2016, the Federal Government of Canada granted US$ 20 million to the Centre for Commercialization of Regenerative Medicine. This grant was utilized to establish a stem-cell therapy development facility in Canada. In addition, the NIH funding for the development of cell therapies has been increasing significantly over the years, which is leading to rise in demand for equipment, media, reagents, and accessories used in cell isolation research.
However, the cell isolation market is hampered by several factors such as stringent regulations, high cost of cell isolation instruments, and ethical issues related to embryonic stem cell research. Cell biology research necessitates the use of animals and humans. These cells are also used for in vivo toxicity and pharmacokinetic testing of drugs, which may harm animals and humans. Also, stem cell research studies use human embryos for clinical applications that often lead to the destruction of embryos. Monitoring of such activities requires stringent regulations which are implemented by regulatory bodies globally. Some of the regulating authorities include Central Ethics Committee for Stem Cell Research (ZES), Human Fertilization and Embryology Authority (HFEA), Human Tissue Authority (HTA), Medicines and Healthcare Products Regulatory Agency (MHRA) and, among others. Hence, with the presence of such ethical concerns and restrictions on the use of cells for research is limiting cell biology research.
Due to the outbreak of COVID-19, research labs have increased their research and development to find solutions which can minimize the symptoms of coronavirus at early stages. This ongoing clinical trials and research is expected to increase the demand for cell isolation products, and hence driving the market growth.
Cell Isolation Market Market Segment Analysis
The cell isolation market is segmented by product type into consumables and instruments. The consumables segment accounted for the largest market share in 2019, due to rising investments by major companies to develop technologically advanced products as well as the repetitive use of consumables. Consumables are further classified into reagents & kits, disposables, and beads. On the other hand, the instruments segment is anticipated to grow at the fastest growth rate over the forecast period, owing to advancements in products such as flow cytometers, centrifuges, magnetic-activated cell separator systems, and filtration systems. The innovations in instruments provide efficient cell separation in diagnostics, research, and other applications.
By cell type, the human cell segment is expected to dominate the global cell isolation market over the forecast period (2020-2027). In human cell therapy, live cells are injected into a patient with cell isolation techniques for the treatment of several chronic diseases. For instance, T-cells are injected into a patient for the treatment of various cancers as these cells are capable of fighting cancer cells during the immunotherapy treatment. On the other hand, the animal type segment is projected to grow significantly over the forecast period, owing to the rising focus on new drug discovery. The drug discovery involves the use of animal cells to examine preliminary efficacy, toxicity, and pharmacokinetics of a new drug molecule.
Based on application, the cell isolation market is segmented into cancer research, stem cell research, in-vitro diagnostics, biomolecule isolation, tissue regeneration, and others. Among these, the biomolecule isolation segment accounted for the largest market share in 2019, owing to increasing focus on the production of biopharmaceuticals, including biosimilars, monoclonal antibodies, and recombinant proteins. Cancer and stem cell research segment are projected to grow at the highest CAGR over the forecast period, due to rising investment in cell-based research by major companies and research laboratories. These are investing heavily for cancer research due to the rising incidence of cancer cases globally.
Based on the technique, the cell isolation market is segmented into the surface marker, centrifugation, and filtration. Among these, the centrifugation-based cell isolation segment is expected to gain maximum share in the coming years, owing to the extensive application of this technique by biotechnology & biopharmaceutical companies, research laboratories, academic institutes, and cell banks. Filtration-based cell isolation is projected to grow significantly over the forecast period due to the advancement in products. The major manufacturers are using advanced filtration systems surface marker to conduct the research and production process for a better quality of the product.
Cell Isolation Market Geographical Analysis
North America region is dominating the global cell isolation market accounted for the largest market share in 2019, owing to advanced healthcare infrastructure for life science research, the large presence of major players focusing on the development of novel treatments, and rising prevalence of cancer in this region. For instance, as per the National Cancer Institute, there were an estimated 1,735,350 new cases of cancer in 2018 that were being diagnosed in the United States. In addition, increasing government support for cancer and stem cell research and the expansion of biotechnology and biopharmaceutical industries globally are contributing to the growth of the market. In April 2018, STEMCELL Technologies announced a US$ 45 million joint agreement between the governments of Canada and British Columbia to help the company build an advanced manufacturing facility.
Europe is the second-largest market for cell isolation growing over the forecast period, owing to several factors such as increasing incidence of chronic diseases, rising research & development in pharmaceutical and biotechnology industries, and growing government investments in life sciences research. In November 2018, GE Healthcare opened a biotechnology manufacturing centre at the Stevenage Bioscience Catalyst (SBC) Open Innovation Campus, in Stevenage, UK. The center would produce a fibre-based purification platform can improve the efficiency in the purification steps of manufacturing biopharmaceuticals, gene therapies and viral vectors.
On the other hand, the Asia-Pacific region is estimated to grow at the fastest growth rate over the forecast period, owing to growing investments by clinical research organizations and biopharmaceutical companies in this region. For instance, in 2018, Merck has invested in the Asia region to build a robust manufacturing and distribution platform for over two years. This investment leads to new biopharmaceutical manufacturing and distribution centers in South Korea and India. Also, in 2018, Terumo has entered into an agreement with UniCAR (China) to advance its CAR T-Cell Therapies research and establish its Center of Excellence in Shanghai, China.
Cell Isolation Market Competitive Landscape
The global cell isolation market is fragmented with major players dominating the market. Some of the major players contributing to the growth of the cell isolation market are Becton Dickinson and Company, Beckman Coulter, Inc., GE Healthcare, Merck KgaA, Miltenyi Biotec, Thermo Fisher Scientific, Bio-Rad Laboratories Inc., among others. The key players are adopting several growth strategies such as product launches, acquisitions, and collaborations, which are contributing to the growth of the Cell Isolation market globally. For instance,
In November 2019, MicroMedicine, Inc., a life sciences technology company, launched its patented one-of-a-kind white blood cell isolation technology, the Sorterra Cell Isolation System. This new automated technology gently and reliably isolates white blood cells from human peripheral blood using microfluidic channels without the use of centrifugation or labelling. Sorterra is intended for use in research and development and clinical research labs.
In 2018, Thermo Fisher Scientific acquired BD Advanced Bioprocessing Unit which includes cell culture media and supplements. It is used in biopharmaceutical applications, including the production of vaccines, monoclonal antibodies, and biosimilar to improve the yield and reduce variability.
In August 2016, GE Healthcare signed an agreement with STEMCELL Technologies Inc., to provide T-Cell reagents for commercial-scale cell therapy production, thus expanding its cell therapy product portfolio.
In November 2016, Thermo Fisher Scientific Inc. acquired MTI-GlobalStem which develops reagents for cell transfection, neurobiology, and stem cell research.
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