A nucleic acid sample preparation is a process in which RNA and DNA is extracted and purified from biological samples that may contain tissue, blood, or other organic matter and prepare them for use. For different research processes such as clinical and medical research, life science or pharmaceutical research, nucleic acid sample preparation is a required step. The main two types of procedures of obtaining DNA or RNA from a sample are by phenol-chloroform extraction and column based extraction. In phenol- chloroform extraction, the DNA or RNA is isolated in aqueous phase while rest of sample is partitioned into the organic phase. In case of column based extraction, the nucleic acid remains adhered to column and the organic material is washed away. Further steps are cutting fragments, labeling and amplifying them. Apart from these, procedures such as centrifugation, electrophoresis, and affinity separation can also be used for obtaining pure nucleic acid. This purified nucleic acid has applications in genetic engineering, molecular diagnosis, and forensics research related to life sciences.
Market Dynamics
Different efforts such as collaborations between key market players and increasing government initiatives like funding to promote research in biotechnological industry is estimated to drive growth of global DNA and RNA sample preparation market. For instance, on February 27, 2020, Purdue university, a U.S.-based public land-grant research university affiliated startups- Amplified Sciences LLC., a U.S.-based life science diagnostic company, and Brightlamp Inc., a U.S.-based computational medicine company, received approvals for up to US$ 250,000 each from the Purdue Foundry Investment Fund for research and development in life science technologies.
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